ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min ribonucleoprotein_complex GO:0030529 12133 569 47 25 9264 46 2 false 6.303056623094677E-19 6.303056623094677E-19 0.0 translational_initiation GO:0006413 12133 160 47 14 7667 38 2 false 1.0516673402183013E-14 1.0516673402183013E-14 0.0 ribosomal_subunit GO:0044391 12133 132 47 13 7199 44 4 false 4.666693720212853E-13 4.666693720212853E-13 2.5906239763169356E-285 translational_elongation GO:0006414 12133 121 47 14 3388 33 2 false 1.193772222578436E-12 1.193772222578436E-12 5.332026529203484E-226 mRNA_metabolic_process GO:0016071 12133 573 47 26 3294 38 1 false 3.6357474386571557E-12 3.6357474386571557E-12 0.0 ribosome GO:0005840 12133 210 47 14 6755 41 3 false 8.593925336918929E-12 8.593925336918929E-12 0.0 cytosolic_part GO:0044445 12133 178 47 13 5117 32 2 false 1.3778923595167913E-11 1.3778923595167913E-11 0.0 multi-organism_cellular_process GO:0044764 12133 634 47 19 9702 46 2 false 1.8540762818257772E-11 1.8540762818257772E-11 0.0 viral_transcription GO:0019083 12133 145 47 13 2964 31 3 false 5.208290777932431E-10 5.208290777932431E-10 1.0927707330622845E-250 RNA_catabolic_process GO:0006401 12133 203 47 14 4368 40 3 false 1.1204876153358061E-9 1.1204876153358061E-9 0.0 macromolecular_complex GO:0032991 12133 3462 47 35 10701 46 1 false 1.364691580668421E-9 1.364691580668421E-9 0.0 RNA_binding GO:0003723 12133 763 47 24 2849 30 1 false 1.485826733655307E-9 1.485826733655307E-9 0.0 protein_targeting GO:0006605 12133 443 47 16 2378 20 2 false 3.867878060308095E-9 3.867878060308095E-9 0.0 protein_complex_disassembly GO:0043241 12133 154 47 13 1031 16 2 false 4.375391219406914E-9 4.375391219406914E-9 4.7545827865276796E-188 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 47 14 1239 17 2 false 4.672171139951601E-9 4.672171139951601E-9 4.427655683668096E-244 cellular_component_disassembly GO:0022411 12133 351 47 13 7663 38 2 false 5.996612138511903E-9 5.996612138511903E-9 0.0 translation GO:0006412 12133 457 47 17 5433 42 3 false 1.3907997450635455E-8 1.3907997450635455E-8 0.0 cellular_process_involved_in_reproduction GO:0048610 12133 469 47 14 9699 46 2 false 1.816650172003581E-8 1.816650172003581E-8 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 47 19 6457 44 3 false 1.9061114480377737E-8 1.9061114480377737E-8 0.0 protein_targeting_to_ER GO:0045047 12133 104 47 13 721 18 3 false 2.7068280234871368E-8 2.7068280234871368E-8 1.514347826459292E-128 macromolecular_complex_disassembly GO:0032984 12133 199 47 13 1380 18 2 false 3.6058341920003086E-8 3.6058341920003086E-8 1.9082717261040364E-246 multi-organism_process GO:0051704 12133 1180 47 20 10446 47 1 false 4.7431632107953296E-8 4.7431632107953296E-8 0.0 structural_molecule_activity GO:0005198 12133 526 47 14 10257 47 1 false 5.2242471721564644E-8 5.2242471721564644E-8 0.0 translational_termination GO:0006415 12133 92 47 13 513 17 2 false 1.1986895728081435E-7 1.1986895728081435E-7 3.4634519853301643E-104 reproductive_process GO:0022414 12133 1275 47 20 10446 47 2 false 1.739618969439042E-7 1.739618969439042E-7 0.0 macromolecule_catabolic_process GO:0009057 12133 820 47 19 6846 44 2 false 1.8962256445892161E-7 1.8962256445892161E-7 0.0 organelle_part GO:0044422 12133 5401 47 40 10701 46 2 false 2.0325015318696944E-7 2.0325015318696944E-7 0.0 reproduction GO:0000003 12133 1345 47 20 10446 47 1 false 4.206028218784068E-7 4.206028218784068E-7 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 47 13 516 16 1 false 6.453554414246057E-7 6.453554414246057E-7 8.917305549619806E-119 structural_constituent_of_ribosome GO:0003735 12133 152 47 13 526 14 1 false 7.032274146025052E-7 7.032274146025052E-7 1.18011379183299E-136 cytosolic_ribosome GO:0022626 12133 92 47 13 296 14 2 false 1.4068408414360795E-6 1.4068408414360795E-6 4.2784789004852985E-79 RNA_processing GO:0006396 12133 601 47 19 3762 39 2 false 1.6364149227629033E-6 1.6364149227629033E-6 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 47 39 6846 44 2 false 2.2220497455185053E-6 2.2220497455185053E-6 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 47 41 7341 43 5 false 4.190580981435903E-6 4.190580981435903E-6 0.0 cellular_metabolic_process GO:0044237 12133 7256 47 45 10007 46 2 false 6.750323761264978E-6 6.750323761264978E-6 0.0 intracellular_protein_transport GO:0006886 12133 658 47 17 1672 19 3 false 7.897841489806129E-6 7.897841489806129E-6 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 47 35 8962 43 1 false 9.340734149103376E-6 9.340734149103376E-6 0.0 organic_cyclic_compound_binding GO:0097159 12133 4407 47 35 8962 43 1 false 1.2686417530765508E-5 1.2686417530765508E-5 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 47 27 10701 46 1 false 1.3051975390484121E-5 1.3051975390484121E-5 0.0 cytosol GO:0005829 12133 2226 47 26 5117 32 1 false 1.3314791928351258E-5 1.3314791928351258E-5 0.0 cellular_macromolecule_localization GO:0070727 12133 918 47 17 2206 19 2 false 1.972539324823301E-5 1.972539324823301E-5 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 47 44 7569 45 2 false 2.3046511809639628E-5 2.3046511809639628E-5 0.0 intracellular_transport GO:0046907 12133 1148 47 19 2815 23 2 false 4.665796885453842E-5 4.665796885453842E-5 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 47 41 7451 44 1 false 5.7762011702349444E-5 5.7762011702349444E-5 0.0 RNA_metabolic_process GO:0016070 12133 3294 47 38 5627 44 2 false 6.233661964043336E-5 6.233661964043336E-5 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 47 41 8027 45 1 false 6.570640732739115E-5 6.570640732739115E-5 0.0 protein_targeting_to_membrane GO:0006612 12133 145 47 13 443 16 1 false 6.951770958604799E-5 6.951770958604799E-5 5.648405296311656E-121 macromolecular_complex_subunit_organization GO:0043933 12133 1256 47 18 3745 25 1 false 9.1639333947615E-5 9.1639333947615E-5 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 47 44 7451 44 1 false 1.0311215815900698E-4 1.0311215815900698E-4 0.0 multi-organism_reproductive_process GO:0044703 12133 707 47 19 1275 20 1 false 1.1715507457375834E-4 1.1715507457375834E-4 0.0 intracellular_organelle_part GO:0044446 12133 5320 47 39 9083 46 3 false 1.235460178637514E-4 1.235460178637514E-4 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 47 24 7502 44 2 false 1.2431541219513952E-4 1.2431541219513952E-4 0.0 catabolic_process GO:0009056 12133 2164 47 24 8027 45 1 false 1.5286820898648511E-4 1.5286820898648511E-4 0.0 cellular_catabolic_process GO:0044248 12133 1972 47 24 7289 45 2 false 1.6156882835751128E-4 1.6156882835751128E-4 0.0 viral_genome_expression GO:0019080 12133 153 47 13 557 19 2 false 1.8214054922662592E-4 1.8214054922662592E-4 1.6461772406083414E-141 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 47 20 5462 41 2 false 2.2543667988758688E-4 2.2543667988758688E-4 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 47 20 5528 41 2 false 2.3597814062886274E-4 2.3597814062886274E-4 0.0 gene_expression GO:0010467 12133 3708 47 38 6052 44 1 false 2.442160505816848E-4 2.442160505816848E-4 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 47 41 7256 45 1 false 2.5146693881810105E-4 2.5146693881810105E-4 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 47 20 5392 41 2 false 2.619687015074274E-4 2.619687015074274E-4 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 47 41 7256 45 1 false 2.6363884558095347E-4 2.6363884558095347E-4 0.0 cellular_localization GO:0051641 12133 1845 47 19 7707 37 2 false 2.720261949188921E-4 2.720261949188921E-4 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 47 20 5388 41 2 false 2.8367654200994746E-4 2.8367654200994746E-4 0.0 viral_infectious_cycle GO:0019058 12133 213 47 15 557 19 1 false 2.8970862445266906E-4 2.8970862445266906E-4 3.455075709157513E-160 spliceosomal_complex GO:0005681 12133 150 47 8 3020 37 2 false 3.467482045551722E-4 3.467482045551722E-4 2.455159410572961E-258 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 47 13 220 14 2 false 3.6282183957036705E-4 3.6282183957036705E-4 1.3850176335002185E-65 cellular_protein_localization GO:0034613 12133 914 47 17 1438 17 2 false 4.269746710925889E-4 4.269746710925889E-4 0.0 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 47 2 6481 36 2 false 4.4377169204547207E-4 4.4377169204547207E-4 9.738359623180132E-21 metabolic_process GO:0008152 12133 8027 47 45 10446 47 1 false 4.661934699431181E-4 4.661934699431181E-4 0.0 establishment_of_protein_localization GO:0045184 12133 1153 47 17 3010 23 2 false 5.453872581933622E-4 5.453872581933622E-4 0.0 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 47 41 7275 45 2 false 5.816045461240232E-4 5.816045461240232E-4 0.0 protein_localization_to_organelle GO:0033365 12133 516 47 16 914 17 1 false 7.773090698706479E-4 7.773090698706479E-4 5.634955900168089E-271 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 47 20 4878 41 5 false 8.187039950307748E-4 8.187039950307748E-4 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 47 28 7980 43 1 false 9.068094999860192E-4 9.068094999860192E-4 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 47 28 7958 43 2 false 9.547683889436309E-4 9.547683889436309E-4 0.0 organelle GO:0043226 12133 7980 47 43 10701 46 1 false 9.978688599658117E-4 9.978688599658117E-4 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 47 4 3151 28 3 false 0.0010079148518267545 0.0010079148518267545 1.4828410310444421E-114 biosynthetic_process GO:0009058 12133 4179 47 34 8027 45 1 false 0.0010316500884454058 0.0010316500884454058 0.0 establishment_of_localization GO:0051234 12133 2833 47 23 10446 47 2 false 0.0011397021374320408 0.0011397021374320408 0.0 nuclear_part GO:0044428 12133 2767 47 27 6936 42 2 false 0.0011711288035991347 0.0011711288035991347 0.0 nuclear_lumen GO:0031981 12133 2490 47 27 3186 27 2 false 0.001248209799372999 0.001248209799372999 0.0 viral_reproductive_process GO:0022415 12133 557 47 19 783 19 2 false 0.0014143170486502757 0.0014143170486502757 1.4346997744229993E-203 macromolecule_localization GO:0033036 12133 1642 47 19 3467 24 1 false 0.0014357920801377187 0.0014357920801377187 0.0 single-organism_transport GO:0044765 12133 2323 47 20 8134 38 2 false 0.0014919297435641982 0.0014919297435641982 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 47 9 2370 13 1 false 0.0018621095192925844 0.0018621095192925844 0.0 nucleus GO:0005634 12133 4764 47 31 7259 35 1 false 0.001968518773481567 0.001968518773481567 0.0 negative_regulation_of_RNA_splicing GO:0033119 12133 15 47 3 1037 19 3 false 0.0020681404863793283 0.0020681404863793283 8.39457188486895E-34 organic_substance_biosynthetic_process GO:1901576 12133 4134 47 34 7470 44 2 false 0.0021032738734948248 0.0021032738734948248 0.0 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 47 2 3020 37 2 false 0.0021245023770970753 0.0021245023770970753 9.537822615543818E-19 macromolecule_biosynthetic_process GO:0009059 12133 3475 47 33 6537 44 2 false 0.0023881997127106497 0.0023881997127106497 0.0 ligase_activity GO:0016874 12133 504 47 6 4901 15 1 false 0.002551783152651689 0.002551783152651689 0.0 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 47 3 243 5 2 false 0.002632446095006018 0.002632446095006018 1.7559807727942103E-26 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 47 14 174 14 1 false 0.0029415453251384035 0.0029415453251384035 2.5039480990851377E-47 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 47 7 201 13 3 false 0.003106920235867228 0.003106920235867228 2.854176062301069E-41 cytoplasmic_transport GO:0016482 12133 666 47 17 1148 19 1 false 0.003152272241143736 0.003152272241143736 0.0 immune_response-regulating_signaling_pathway GO:0002764 12133 310 47 5 3626 14 2 false 0.004636158136278155 0.004636158136278155 0.0 regulation_of_ligase_activity GO:0051340 12133 98 47 3 2061 8 2 false 0.004905246681297977 0.004905246681297977 1.6310105681359867E-170 nucleic_acid_binding GO:0003676 12133 2849 47 30 4407 35 2 false 0.0049715130650466585 0.0049715130650466585 0.0 cellular_biosynthetic_process GO:0044249 12133 4077 47 34 7290 45 2 false 0.00507280180674457 0.00507280180674457 0.0 establishment_of_localization_in_cell GO:0051649 12133 1633 47 19 2978 23 2 false 0.005097666239199543 0.005097666239199543 0.0 Prp19_complex GO:0000974 12133 78 47 3 2976 14 1 false 0.005119947421013519 0.005119947421013519 3.570519754703887E-156 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 47 33 6146 44 3 false 0.005162273092111403 0.005162273092111403 0.0 small_molecule_binding GO:0036094 12133 2102 47 18 8962 43 1 false 0.005598547598006024 0.005598547598006024 0.0 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 47 32 5597 41 2 false 0.005717067305850133 0.005717067305850133 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 47 32 5588 41 2 false 0.006027019100273496 0.006027019100273496 0.0 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 47 32 5686 41 2 false 0.006223748167770555 0.006223748167770555 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 47 4 2025 9 2 false 0.006243466405478172 0.006243466405478172 5.184659787643375E-271 intracellular_receptor_signaling_pathway GO:0030522 12133 217 47 4 3547 13 1 false 0.006283916015656976 0.006283916015656976 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 47 32 5629 41 2 false 0.006719959402083921 0.006719959402083921 0.0 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 47 3 1385 13 2 false 0.006852319302487002 0.006852319302487002 3.166663017097352E-84 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 47 5 1525 9 1 false 0.007170185875538124 0.007170185875538124 1.2095302863090285E-289 localization GO:0051179 12133 3467 47 24 10446 47 1 false 0.008361247277743872 0.008361247277743872 0.0 organic_substance_transport GO:0071702 12133 1580 47 19 2783 23 1 false 0.008470532120812658 0.008470532120812658 0.0 positive_regulation_of_ligase_activity GO:0051351 12133 84 47 3 1424 8 3 false 0.00894015304905541 0.00894015304905541 5.130084211911676E-138 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 47 13 145 13 1 false 0.00926149380222918 0.00926149380222918 1.7288474062512548E-37 positive_regulation_of_chromosome_organization GO:2001252 12133 49 47 2 847 3 3 false 0.009481883488733338 0.009481883488733338 8.5635846172251E-81 mRNA_catabolic_process GO:0006402 12133 181 47 14 592 26 2 false 0.009756215187312966 0.009756215187312966 1.4563864024176219E-157 clathrin_coat_of_coated_pit GO:0030132 12133 14 47 1 1370 1 3 false 0.010218978102197114 0.010218978102197114 1.135698186932346E-33 negative_regulation_of_dephosphorylation GO:0035305 12133 6 47 1 562 1 3 false 0.01067615658362861 0.01067615658362861 2.3471675405869638E-14 RNA_splicing GO:0008380 12133 307 47 15 601 19 1 false 0.0112002670934714 0.0112002670934714 4.262015823312228E-180 negative_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060266 12133 3 47 1 738 3 8 false 0.012162042985682775 0.012162042985682775 1.4988203684165303E-8 response_to_growth_factor_stimulus GO:0070848 12133 545 47 6 1783 8 1 false 0.012297429056281622 0.012297429056281622 0.0 intracellular_part GO:0044424 12133 9083 47 46 9983 46 2 false 0.01282517927892043 0.01282517927892043 0.0 immune_response GO:0006955 12133 1006 47 9 5335 22 2 false 0.01368302440401005 0.01368302440401005 0.0 molecular_function GO:0003674 12133 10257 47 47 11221 47 1 false 0.014538837123103204 0.014538837123103204 0.0 pigment_granule GO:0048770 12133 87 47 3 712 5 1 false 0.014697052830415247 0.014697052830415247 3.4546414966613156E-114 maturation_of_SSU-rRNA GO:0030490 12133 8 47 2 104 3 2 false 0.015068312612572342 0.015068312612572342 3.8823564737710265E-12 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 47 25 10446 47 1 false 0.015487176250208748 0.015487176250208748 0.0 regulation_of_RNA_stability GO:0043487 12133 37 47 2 2240 12 2 false 0.015791884204517482 0.015791884204517482 2.0388833014238124E-81 mesangial_cell_development GO:0072143 12133 5 47 1 1256 4 2 false 0.015847559641176404 0.015847559641176404 3.869857243416382E-14 regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060264 12133 4 47 1 1701 7 6 false 0.016373930254631103 0.016373930254631103 2.8769144126071423E-12 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 47 2 705 4 3 false 0.01668278529979959 0.01668278529979959 4.9570646354646075E-65 negative_regulation_of_muscle_cell_differentiation GO:0051148 12133 33 47 2 584 4 3 false 0.017313416799157676 0.017313416799157676 1.1148204606376211E-54 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 47 3 987 6 2 false 0.017473306549173177 0.017473306549173177 9.48284116235963E-143 cellular_sodium_ion_homeostasis GO:0006883 12133 5 47 1 283 1 3 false 0.017667844522967165 0.017667844522967165 6.84978827344915E-11 regulation_of_immune_response GO:0050776 12133 533 47 7 2461 14 3 false 0.017678877447357848 0.017678877447357848 0.0 positive_regulation_of_myelination GO:0031643 12133 3 47 1 2842 17 4 false 0.01784422338675721 0.01784422338675721 2.6166016024347513E-10 positive_regulation_of_immune_response GO:0050778 12133 394 47 6 1600 10 4 false 0.017987491964926848 0.017987491964926848 0.0 neurotrophin_signaling_pathway GO:0038179 12133 253 47 4 2018 9 2 false 0.01819701687013019 0.01819701687013019 0.0 nuclear_body GO:0016604 12133 272 47 5 805 6 1 false 0.01861349497147087 0.01861349497147087 8.12188174084084E-223 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 47 2 1977 11 3 false 0.01864377816820114 0.01864377816820114 8.49513097758148E-83 chorion_development GO:0060717 12133 5 47 1 3152 12 2 false 0.018903049923116137 0.018903049923116137 3.8692669693383385E-16 renal_interstitial_cell_development GO:0072141 12133 6 47 1 1256 4 2 false 0.01899433003401099 0.01899433003401099 1.8560466395284897E-16 multi-organism_transport GO:0044766 12133 29 47 2 3441 26 2 false 0.019668956523387418 0.019668956523387418 2.716860412473803E-72 intracellular GO:0005622 12133 9171 47 46 9983 46 1 false 0.020005956953034712 0.020005956953034712 0.0 positive_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060265 12133 2 47 1 589 6 7 false 0.020286892346074205 0.020286892346074205 5.774805677789514E-6 phosphoprotein_binding GO:0051219 12133 42 47 2 6397 34 1 false 0.020673389724355912 0.020673389724355912 2.265958128878875E-109 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 47 11 374 13 2 false 0.021052269263075667 0.021052269263075667 2.0954491420584897E-111 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 47 2 3208 18 2 false 0.021426986294141342 0.021426986294141342 7.591030632914061E-95 regulation_of_myelination GO:0031641 12133 13 47 1 601 1 4 false 0.021630615640600453 0.021630615640600453 5.31705801100533E-27 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 47 4 1097 10 3 false 0.021780783714287662 0.021780783714287662 8.208279871491876E-172 positive_regulation_of_histone_modification GO:0031058 12133 40 47 2 963 6 4 false 0.02270865128174636 0.02270865128174636 8.380486405163906E-72 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 47 3 856 3 3 false 0.02295692502285049 0.02295692502285049 2.175375701359491E-221 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 47 2 1014 3 1 false 0.023490747235918784 0.023490747235918784 2.468210871514413E-134 glomerular_mesangial_cell_development GO:0072144 12133 4 47 1 167 1 4 false 0.023952095808382517 0.023952095808382517 3.199328908768443E-8 smooth_muscle_contractile_fiber GO:0030485 12133 4 47 1 159 1 2 false 0.025157232704403044 0.025157232704403044 3.900612243998485E-8 negative_regulation_of_respiratory_burst GO:0060268 12133 3 47 1 1370 12 3 false 0.026066746419598927 0.026066746419598927 2.3385202648234984E-9 pseudopodium GO:0031143 12133 13 47 1 976 2 1 false 0.026475409836085474 0.026475409836085474 9.253153669613935E-30 clathrin_coat_of_trans-Golgi_network_vesicle GO:0030130 12133 11 47 1 414 1 3 false 0.02657004830918312 0.02657004830918312 7.453188898335812E-22 negative_regulation_of_protein_dephosphorylation GO:0035308 12133 4 47 1 444 3 4 false 0.02684427581518413 0.02684427581518413 6.259846539070891E-10 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 47 7 1975 9 1 false 0.027297544578030346 0.027297544578030346 0.0 protein_transport GO:0015031 12133 1099 47 17 1627 19 2 false 0.028034451398786873 0.028034451398786873 0.0 positive_regulation_of_immune_system_process GO:0002684 12133 540 47 7 3595 21 3 false 0.028541265874257725 0.028541265874257725 0.0 DNA_repair GO:0006281 12133 368 47 5 977 6 2 false 0.03080377829719192 0.03080377829719192 3.284245924949814E-280 receptor_signaling_protein_activity GO:0005057 12133 339 47 3 1070 3 1 false 0.03160920432211269 0.03160920432211269 2.5248591221043436E-289 protein_metabolic_process GO:0019538 12133 3431 47 27 7395 44 2 false 0.032534697723760525 0.032534697723760525 0.0 negative_regulation_of_glial_cell_proliferation GO:0060253 12133 8 47 1 472 2 4 false 0.03364640685162486 0.03364640685162486 1.7373419800577642E-17 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 47 2 1199 10 2 false 0.03390882647561764 0.03390882647561764 9.194442294553035E-70 positive_regulation_of_respiratory_burst GO:0060267 12133 5 47 1 1885 13 3 false 0.034046047105899355 0.034046047105899355 5.069092992061398E-15 biological_process GO:0008150 12133 10446 47 47 11221 47 1 false 0.03436011404806191 0.03436011404806191 0.0 DNA_catabolic_process,_exonucleolytic GO:0000738 12133 9 47 1 257 1 2 false 0.03501945525291883 0.03501945525291883 8.548342373692236E-17 RNA_helicase_activity GO:0003724 12133 27 47 2 140 2 1 false 0.03607399794449906 0.03607399794449906 1.8047202528374888E-29 ubiquitin_ligase_complex GO:0000151 12133 147 47 3 9248 46 2 false 0.036330433739791695 0.036330433739791695 0.0 negative_regulation_of_sodium_ion_transport GO:0010766 12133 5 47 1 135 1 3 false 0.03703703703703773 0.03703703703703773 2.884335739945468E-9 ubiquitin_conjugating_enzyme_complex GO:0031371 12133 8 47 1 9248 46 2 false 0.03912103502414612 0.03912103502414612 7.5588062911204355E-28 snRNA_modification GO:0040031 12133 3 47 1 76 1 2 false 0.03947368421052582 0.03947368421052582 1.4224751066856055E-5 LUBAC_complex GO:0071797 12133 2 47 1 147 3 1 false 0.04053676265026619 0.04053676265026619 9.318796011554947E-5 positive_regulation_of_defense_response GO:0031349 12133 229 47 4 1621 10 3 false 0.04065273777402867 0.04065273777402867 6.85443065618377E-286 cell_part GO:0044464 12133 9983 47 46 10701 46 2 false 0.040687268365966575 0.040687268365966575 0.0 cell GO:0005623 12133 9984 47 46 10701 46 1 false 0.04087559744057598 0.04087559744057598 0.0 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 47 32 4989 41 5 false 0.040904298591048494 0.040904298591048494 0.0 water_homeostasis GO:0030104 12133 14 47 1 677 2 1 false 0.04096125440292892 0.04096125440292892 2.3492827505763342E-29 glial_cell_proliferation GO:0014009 12133 19 47 1 1373 3 2 false 0.04097252547587459 0.04097252547587459 3.3395512559534237E-43 male_sex_determination GO:0030238 12133 13 47 1 3069 10 2 false 0.04162060087097136 0.04162060087097136 2.9810795844016348E-36 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 47 2 22 2 1 false 0.04329004329004321 0.04329004329004321 3.79737221842484E-5 regulation_of_response_to_stimulus GO:0048583 12133 2074 47 13 7292 29 2 false 0.043731516540913104 0.043731516540913104 0.0 ribonucleoprotein_complex_assembly GO:0022618 12133 117 47 3 646 5 3 false 0.0437857910114512 0.0437857910114512 4.631331466925404E-132 regulation_of_glial_cell_proliferation GO:0060251 12133 15 47 1 1013 3 3 false 0.04381060082247432 0.04381060082247432 1.1956112131119994E-33 cardiovascular_system_development GO:0072358 12133 655 47 5 2686 9 2 false 0.044021461347206914 0.044021461347206914 0.0 circulatory_system_development GO:0072359 12133 655 47 5 2686 9 1 false 0.044021461347206914 0.044021461347206914 0.0 endocytosis GO:0006897 12133 411 47 4 895 4 2 false 0.04411967273380709 0.04411967273380709 2.7872223899360555E-267 regulation_of_protein_ubiquitination GO:0031396 12133 176 47 4 1344 11 2 false 0.0445838349978632 0.0445838349978632 8.0617715234352E-226 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 47 6 1356 8 2 false 0.04474276473580815 0.04474276473580815 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 47 8 5778 22 3 false 0.045445675802321964 0.045445675802321964 0.0 cytoplasmic_part GO:0044444 12133 5117 47 32 9083 46 2 false 0.0463013469522348 0.0463013469522348 0.0 regulation_of_signal_transduction GO:0009966 12133 1603 47 10 3826 15 4 false 0.04677714001088461 0.04677714001088461 0.0 positive_regulation_of_histone_H3-K36_methylation GO:0000416 12133 1 47 1 21 1 3 false 0.04761904761904764 0.04761904761904764 0.04761904761904764 hormone_receptor_binding GO:0051427 12133 122 47 2 918 3 1 false 0.04801370752195857 0.04801370752195857 1.5301276126382055E-155 intracellular_organelle_lumen GO:0070013 12133 2919 47 27 5320 39 2 false 0.04815032730279571 0.04815032730279571 0.0 protein_linear_polyubiquitination GO:0097039 12133 2 47 1 163 4 1 false 0.048625312428993664 0.048625312428993664 7.574036203892231E-5 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 47 2 1663 10 2 false 0.049281107500122136 0.049281107500122136 5.186655572840897E-113 regulation_of_isotype_switching GO:0045191 12133 17 47 1 1018 3 6 false 0.049313937858007126 0.049313937858007126 3.003945250869009E-37 immune_system_process GO:0002376 12133 1618 47 12 10446 47 1 false 0.05058675669001224 0.05058675669001224 0.0 regulation_of_respiratory_burst GO:0060263 12133 9 47 1 4476 26 2 false 0.05112508895545006 0.05112508895545006 5.072797550268562E-28 intracellular_transport_of_viral_material GO:0075733 12133 23 47 2 355 6 2 false 0.051409945127484105 0.051409945127484105 1.1844258992565298E-36 negative_regulation_of_metabolic_process GO:0009892 12133 1354 47 12 8327 45 3 false 0.051448214387258134 0.051448214387258134 0.0 connective_tissue_development GO:0061448 12133 156 47 2 1132 3 1 false 0.05151117489824355 0.05151117489824355 2.187737558502385E-196 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 47 3 1112 3 4 false 0.052497141606074 0.052497141606074 1.302733E-318 regulation_of_immune_system_process GO:0002682 12133 794 47 7 6789 30 2 false 0.0536022742773998 0.0536022742773998 0.0 small_conjugating_protein_binding GO:0032182 12133 71 47 2 6397 34 1 false 0.054245764573748 0.054245764573748 7.493300865579233E-169 vesicle_membrane GO:0012506 12133 312 47 4 9991 46 4 false 0.05458132317383 0.05458132317383 0.0 production_of_molecular_mediator_involved_in_inflammatory_response GO:0002532 12133 18 47 1 4184 13 2 false 0.054582547551231285 0.054582547551231285 4.3012458861645E-50 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 47 3 1130 6 2 false 0.05491032996036138 0.05491032996036138 1.9819409219356823E-214 regulation_of_potassium_ion_transmembrane_transport GO:1901379 12133 12 47 1 216 1 3 false 0.05555555555555571 0.05555555555555571 6.338882729411382E-20 positive_regulation_of_DNA-dependent_transcription,_initiation GO:2000144 12133 7 47 1 1100 9 4 false 0.05603522040195232 0.05603522040195232 2.6362658013915236E-18 respiratory_burst GO:0045730 12133 21 47 1 2877 8 1 false 0.05699152326809251 0.05699152326809251 1.2658513282149024E-53 positive_regulation_of_signal_transduction GO:0009967 12133 782 47 6 3650 14 5 false 0.0587871127609498 0.0587871127609498 0.0 regulation_of_potassium_ion_transmembrane_transporter_activity GO:1901016 12133 9 47 1 153 1 3 false 0.05882352941176151 0.05882352941176151 1.0038611131963863E-14 regulation_of_organelle_organization GO:0033043 12133 519 47 5 2487 11 2 false 0.05887158492843444 0.05887158492843444 0.0 positive_regulation_of_ion_transmembrane_transporter_activity GO:0032414 12133 28 47 1 473 1 3 false 0.059196617336147846 0.059196617336147846 8.750359231366189E-46 regulation_of_histone_ubiquitination GO:0033182 12133 4 47 1 265 4 3 false 0.05935341153100818 0.05935341153100818 4.978567515771174E-9 DNA-dependent_transcription,_termination GO:0006353 12133 80 47 3 2751 31 2 false 0.05936905324724063 0.05936905324724063 1.5820458311792457E-156 sex_determination GO:0007530 12133 21 47 1 340 1 1 false 0.0617647058823462 0.0617647058823462 6.623492102010024E-34 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 47 3 750 3 3 false 0.06297950208128138 0.06297950208128138 3.090255244762607E-218 epithelial_cell_differentiation_involved_in_kidney_development GO:0035850 12133 31 47 1 491 1 3 false 0.06313645621180647 0.06313645621180647 8.158001597817135E-50 phosphoserine_binding GO:0050815 12133 4 47 1 125 2 2 false 0.06322580645161026 0.06322580645161026 1.0318453263855228E-7 regulation_of_histone_H3-K36_methylation GO:0000414 12133 2 47 1 31 1 2 false 0.0645161290322579 0.0645161290322579 0.002150537634408595 regulation_of_histone_modification GO:0031056 12133 77 47 2 1240 7 3 false 0.06521879633886025 0.06521879633886025 1.0351200557646026E-124 telomeric_DNA_binding GO:0042162 12133 16 47 1 1189 5 1 false 0.0656042849521189 0.0656042849521189 1.4512187070438412E-36 channel_inhibitor_activity GO:0016248 12133 20 47 1 304 1 2 false 0.06578947368420382 0.06578947368420382 1.0141079171115058E-31 positive_regulation_of_sodium_ion_transport GO:0010765 12133 11 47 1 166 1 3 false 0.06626506024096748 0.06626506024096748 2.123209741249517E-17 adipose_tissue_development GO:0060612 12133 19 47 1 1929 7 2 false 0.06704469406011337 0.06704469406011337 5.039701939128339E-46 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 47 2 695 4 3 false 0.06731225658088678 0.06731225658088678 3.5521820546065696E-107 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 47 3 912 3 2 false 0.0691921927803203 0.0691921927803203 2.059888800891414E-267 mitogen-activated_protein_kinase_kinase_binding GO:0031434 12133 12 47 1 341 2 1 false 0.06924271174744936 0.06924271174744936 2.356690583847287E-22 sodium_channel_inhibitor_activity GO:0019871 12133 3 47 1 43 1 3 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 ion_channel_inhibitor_activity GO:0008200 12133 20 47 1 286 1 2 false 0.06993006993007066 0.06993006993007066 3.5818833657211076E-31 positive_regulation_of_cell_communication GO:0010647 12133 820 47 6 4819 18 3 false 0.07065920612437904 0.07065920612437904 0.0 respiratory_burst_involved_in_defense_response GO:0002679 12133 9 47 1 1100 9 3 false 0.0715238998134488 0.0715238998134488 1.590299388551981E-22 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 47 1 856 7 3 false 0.07156024342260274 0.07156024342260274 1.5339974177634096E-21 DNA_double-strand_break_processing GO:0000729 12133 8 47 1 110 1 2 false 0.07272727272727175 0.07272727272727175 2.4407768686605466E-12 organelle_lumen GO:0043233 12133 2968 47 27 5401 40 2 false 0.07346193467127274 0.07346193467127274 0.0 cellular_response_to_oxygen_levels GO:0071453 12133 85 47 2 1663 9 2 false 0.07357175923623682 0.07357175923623682 4.192529980934564E-145 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 47 2 2735 16 4 false 0.07444372714240784 0.07444372714240784 2.836340851870023E-153 RNA_biosynthetic_process GO:0032774 12133 2751 47 31 4191 40 3 false 0.07460848762374364 0.07460848762374364 0.0 positive_regulation_of_cation_channel_activity GO:2001259 12133 17 47 1 224 1 3 false 0.07589285714285353 0.07589285714285353 7.366387194248368E-26 establishment_of_RNA_localization GO:0051236 12133 124 47 3 2839 23 2 false 0.07619739075248069 0.07619739075248069 1.4765023034812589E-220 response_to_hypoxia GO:0001666 12133 200 47 3 2540 13 2 false 0.07640816066639235 0.07640816066639235 2.6634431659671552E-303 trivalent_inorganic_cation_transport GO:0072512 12133 24 47 1 606 2 1 false 0.07770231568614161 0.07770231568614161 1.6359412389907096E-43 trans-Golgi_network_transport_vesicle_membrane GO:0012510 12133 12 47 1 151 1 4 false 0.07947019867549363 0.07947019867549363 5.3388603233551054E-18 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 47 6 200 13 3 false 0.0800460795361982 0.0800460795361982 7.491323649368413E-49 nucleolus_organization GO:0007000 12133 5 47 1 62 1 1 false 0.08064516129032337 0.08064516129032337 1.545355726980193E-7 RNA_export_from_nucleus GO:0006405 12133 72 47 3 165 3 2 false 0.08112850788296484 0.08112850788296484 1.3059643179360761E-48 translation_initiation_factor_binding GO:0031369 12133 16 47 1 6397 34 1 false 0.0818248007332668 0.0818248007332668 2.711136666436817E-48 regulation_of_protein_dephosphorylation GO:0035304 12133 14 47 1 1152 7 3 false 0.08223663943583057 0.08223663943583057 1.3017113495112525E-32 negative_regulation_of_ligase_activity GO:0051352 12133 71 47 2 1003 7 3 false 0.08229531999617463 0.08229531999617463 8.698138776450475E-111 activation_of_MAPKK_activity GO:0000186 12133 64 47 2 496 4 3 false 0.0828100223989465 0.0828100223989465 2.7437381948522894E-82 exon-exon_junction_complex GO:0035145 12133 12 47 1 4399 32 2 false 0.08398427488954317 0.08398427488954317 9.260000367357379E-36 rRNA_processing GO:0006364 12133 102 47 3 231 3 3 false 0.08467325346002468 0.08467325346002468 2.6685808966337758E-68 positive_regulation_of_signaling GO:0023056 12133 817 47 6 4861 19 3 false 0.08480113010152975 0.08480113010152975 0.0 cellular_monovalent_inorganic_cation_homeostasis GO:0030004 12133 26 47 1 306 1 2 false 0.08496732026142838 0.08496732026142838 2.8281153145438213E-38 eukaryotic_translation_initiation_factor_3_complex GO:0005852 12133 16 47 1 6481 36 2 false 0.08536163187942238 0.08536163187942238 2.1998593675926732E-48 Leydig_cell_differentiation GO:0033327 12133 10 47 1 2446 22 4 false 0.08654128555588958 0.08654128555588958 4.821684083574537E-28 activation_of_immune_response GO:0002253 12133 341 47 5 1618 12 2 false 0.0869352827449904 0.0869352827449904 0.0 sodium_ion_homeostasis GO:0055078 12133 26 47 1 299 1 2 false 0.08695652173913307 0.08695652173913307 5.299686091705976E-38 positive_regulation_of_organelle_organization GO:0010638 12133 217 47 3 2191 11 3 false 0.08704288814770014 0.08704288814770014 1.6765812392172608E-306 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 47 6 742 7 2 false 0.08787095750783266 0.08787095750783266 9.121396596563632E-222 cellular_protein_complex_localization GO:0034629 12133 5 47 1 930 17 2 false 0.08830009659507855 0.08830009659507855 1.7435880605018067E-13 signal_transduction_by_phosphorylation GO:0023014 12133 307 47 3 3947 14 2 false 0.08938597018127756 0.08938597018127756 0.0 cell_cycle GO:0007049 12133 1295 47 10 7541 37 1 false 0.08945476790983756 0.08945476790983756 0.0 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 47 3 522 5 3 false 0.08982589817173127 0.08982589817173127 1.2617392241842968E-123 trans-Golgi_network_transport_vesicle GO:0030140 12133 23 47 1 256 1 3 false 0.08984374999999867 0.08984374999999867 2.9196979468044646E-33 regulation_of_chromosome_organization GO:0033044 12133 114 47 2 1070 5 2 false 0.09079287181549021 0.09079287181549021 5.856752364330647E-157 histone_H3-K36_methylation GO:0010452 12133 6 47 1 66 1 1 false 0.09090909090909147 0.09090909090909147 1.1006092444484753E-8 cellular_response_to_hypoxia GO:0071456 12133 79 47 2 1210 8 3 false 0.09119420841252757 0.09119420841252757 3.484581288071841E-126 positive_regulation_of_DNA_metabolic_process GO:0051054 12133 92 47 2 2322 13 4 false 0.09123348810224213 0.09123348810224213 1.6937907011714837E-167 ephrin_receptor_binding GO:0046875 12133 29 47 1 918 3 1 false 0.09190589577385679 0.09190589577385679 1.6526990639165767E-55 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 47 2 86 2 2 false 0.09603283173734763 0.09603283173734763 6.233113581740502E-23 regulation_of_DNA-dependent_transcription,_initiation GO:2000142 12133 15 47 1 2670 18 3 false 0.09673011335997732 0.09673011335997732 5.444282950561458E-40 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 47 9 4597 17 2 false 0.09728930263031679 0.09728930263031679 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 47 4 1384 13 2 false 0.0975655365246157 0.0975655365246157 1.3395090025049634E-243 cell_motility GO:0048870 12133 785 47 5 1249 5 3 false 0.09760552403245856 0.09760552403245856 0.0 defense_response GO:0006952 12133 1018 47 8 2540 13 1 false 0.09813664675338907 0.09813664675338907 0.0 MAP_kinase_kinase_activity GO:0004708 12133 74 47 2 521 4 3 false 0.09864488412296014 0.09864488412296014 6.903948166738437E-92 positive_regulation_of_innate_immune_response GO:0045089 12133 178 47 4 740 8 4 false 0.0999757332622427 0.0999757332622427 1.4450011889246649E-176 regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060260 12133 13 47 1 1243 10 3 false 0.10014445418648181 0.10014445418648181 3.9219319072235074E-31 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 47 2 197 3 3 false 0.10058013052937212 0.10058013052937212 3.777320475653026E-42 regulation_of_cell_communication GO:0010646 12133 1796 47 11 6469 27 2 false 0.10062250642412207 0.10062250642412207 0.0 regulation_of_signaling GO:0023051 12133 1793 47 11 6715 28 2 false 0.10062633101262944 0.10062633101262944 0.0 sodium_channel_activity GO:0005272 12133 26 47 1 256 1 3 false 0.10156249999999863 0.10156249999999863 3.647595212320824E-36 renal_system_vasculature_development GO:0061437 12133 20 47 1 571 3 2 false 0.10161311669169311 0.10161311669169311 2.509501501235589E-37 cytoplasmic_vesicle_membrane GO:0030659 12133 302 47 4 719 5 3 false 0.10254119386710471 0.10254119386710471 1.2351303462379864E-211 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 47 3 3020 37 2 false 0.10366703394828963 0.10366703394828963 1.1070924240418437E-179 paraspeckles GO:0042382 12133 6 47 1 272 5 1 false 0.10628418301342021 0.10628418301342021 1.8794561691225117E-12 response_to_abiotic_stimulus GO:0009628 12133 676 47 5 5200 20 1 false 0.10784652835099379 0.10784652835099379 0.0 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 47 2 1056 8 3 false 0.1078891051945269 0.1078891051945269 4.764817151311381E-118 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 47 3 859 6 3 false 0.10872328386940822 0.10872328386940822 3.480270935062193E-190 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 47 4 587 5 2 false 0.10898669616026918 0.10898669616026918 2.854325455984618E-173 muscle_cell_differentiation GO:0042692 12133 267 47 3 2218 10 2 false 0.10904468544685832 0.10904468544685832 0.0 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 47 2 2180 11 2 false 0.10954834630252996 0.10954834630252996 1.341003616993524E-193 response_to_stress GO:0006950 12133 2540 47 13 5200 20 1 false 0.11022924102550019 0.11022924102550019 0.0 cellular_response_to_stress GO:0033554 12133 1124 47 7 4743 18 2 false 0.11049624168487882 0.11049624168487882 0.0 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 47 2 6380 27 3 false 0.11073298801488413 0.11073298801488413 2.5067679665083333E-283 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 47 11 7606 45 4 false 0.11136784735756891 0.11136784735756891 0.0 response_to_virus GO:0009615 12133 230 47 3 475 3 1 false 0.11276259801429628 0.11276259801429628 3.548520767075247E-142 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 47 6 1730 10 2 false 0.11350615736965206 0.11350615736965206 0.0 vascular_smooth_muscle_contraction GO:0014829 12133 10 47 1 88 1 2 false 0.11363636363636048 0.11363636363636048 2.215493107028815E-13 coated_membrane GO:0048475 12133 66 47 1 4398 8 1 false 0.11402062923121394 0.11402062923121394 3.1181974111959693E-148 virion_assembly GO:0019068 12133 11 47 1 2070 23 4 false 0.11591835814173561 0.11591835814173561 1.3710102562261885E-29 protein_deneddylation GO:0000338 12133 9 47 1 77 1 1 false 0.1168831168831165 0.1168831168831165 6.198761061406022E-12 U12-type_spliceosomal_complex GO:0005689 12133 24 47 3 150 8 1 false 0.11709685952868545 0.11709685952868545 2.5760759444825708E-28 positive_regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060261 12133 6 47 1 196 4 3 false 0.11780388832898002 0.11780388832898002 1.3719812583394723E-11 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 47 3 417 3 4 false 0.11792410371980254 0.11792410371980254 8.022991700655629E-125 positive_regulation_of_protein_acetylation GO:1901985 12133 17 47 1 823 6 3 false 0.11805087664834522 0.11805087664834522 1.1521858928998402E-35 regulation_of_blood_pressure GO:0008217 12133 117 47 2 2120 11 2 false 0.11996056146160647 0.11996056146160647 6.820682324461924E-196 histone_pre-mRNA_DCP_binding GO:0071208 12133 4 47 1 763 24 1 false 0.1202316296304116 0.1202316296304116 7.13729230310747E-11 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 47 5 2556 7 1 false 0.12159906537309446 0.12159906537309446 0.0 cellular_protein_metabolic_process GO:0044267 12133 3038 47 27 5899 44 2 false 0.12223699760480265 0.12223699760480265 0.0 positive_regulation_of_transporter_activity GO:0032411 12133 34 47 1 2101 8 4 false 0.12255488427687236 0.12255488427687236 4.2098203958278254E-75 positive_regulation_of_biological_process GO:0048518 12133 3081 47 18 10446 47 2 false 0.12297955497592394 0.12297955497592394 0.0 glomerulus_vasculature_development GO:0072012 12133 19 47 1 444 3 3 false 0.12322897650205968 0.12322897650205968 9.004361904208676E-34 trans-Golgi_network_membrane GO:0032588 12133 26 47 1 9083 46 3 false 0.12382688581848855 0.12382688581848855 5.095783492585907E-77 kidney_vasculature_development GO:0061440 12133 20 47 1 161 1 2 false 0.1242236024844735 0.1242236024844735 6.083753393714536E-26 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 47 5 1079 7 3 false 0.12429187446995911 0.12429187446995911 5.98264E-319 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 47 3 362 6 4 false 0.12460576966852555 0.12460576966852555 1.827388630734988E-82 fibroblast_growth_factor_binding GO:0017134 12133 17 47 1 135 1 1 false 0.12592592592592816 0.12592592592592816 6.193063943061966E-22 response_to_peptide GO:1901652 12133 322 47 2 904 2 2 false 0.1266207038486307 0.1266207038486307 7.8711156655671515E-255 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 47 2 1813 9 1 false 0.12683297325944345 0.12683297325944345 4.219154160176784E-199 regulation_of_developmental_process GO:0050793 12133 1233 47 8 7209 30 2 false 0.12691610324515215 0.12691610324515215 0.0 negative_regulation_of_gliogenesis GO:0014014 12133 25 47 1 196 1 3 false 0.12755102040816754 0.12755102040816754 3.789218356295807E-32 positive_regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902110 12133 37 47 1 1374 5 3 false 0.127760586973444 0.127760586973444 1.7604614397711276E-73 cellular_process GO:0009987 12133 9675 47 46 10446 47 1 false 0.12860618496725448 0.12860618496725448 0.0 negative_regulation_of_inflammatory_response GO:0050728 12133 56 47 1 432 1 4 false 0.12962962962960567 0.12962962962960567 7.653768457766755E-72 glomerular_mesangium_development GO:0072109 12133 11 47 1 163 2 2 false 0.13080360524121898 0.13080360524121898 2.611469323021833E-17 hippo_signaling_cascade GO:0035329 12133 28 47 1 1813 9 1 false 0.13098345038937115 0.13098345038937115 2.187819615524224E-62 nucleoside_metabolic_process GO:0009116 12133 1083 47 5 2072 6 4 false 0.1317579477863481 0.1317579477863481 0.0 regulation_of_gliogenesis GO:0014013 12133 55 47 1 415 1 2 false 0.13253012048192345 0.13253012048192345 5.469629156149037E-70 helicase_activity GO:0004386 12133 140 47 2 1059 5 1 false 0.1325937728451892 0.1325937728451892 6.632628106941949E-179 homeostasis_of_number_of_cells GO:0048872 12133 166 47 2 990 4 1 false 0.13299872798134393 0.13299872798134393 1.128853988781411E-193 positive_regulation_of_peptidyl-lysine_acetylation GO:2000758 12133 17 47 1 127 1 3 false 0.13385826771653558 0.13385826771653558 1.8751500945612253E-21 regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902108 12133 39 47 1 1375 5 3 false 0.13418243260070947 0.13418243260070947 1.4191902379759833E-76 regulation_of_potassium_ion_transport GO:0043266 12133 32 47 1 238 1 2 false 0.13445378151259108 0.13445378151259108 2.0777607490676014E-40 multivesicular_body_sorting_pathway GO:0071985 12133 17 47 1 2490 21 2 false 0.13450019434803023 0.13450019434803023 6.909596477174519E-44 negative_regulation_of_innate_immune_response GO:0045824 12133 14 47 1 685 7 4 false 0.13514348553762542 0.13514348553762542 1.989838073929195E-29 regulation_of_cation_channel_activity GO:2001257 12133 33 47 1 244 1 2 false 0.13524590163933084 0.13524590163933084 1.3783310605710322E-41 regulation_of_tight_junction_assembly GO:2000810 12133 8 47 1 58 1 2 false 0.13793103448276028 0.13793103448276028 5.217035699399583E-10 regulation_of_transmembrane_transporter_activity GO:0022898 12133 78 47 1 563 1 3 false 0.13854351687388652 0.13854351687388652 8.813007984613145E-98 vacuolar_protein_catabolic_process GO:0007039 12133 10 47 1 409 6 1 false 0.13881853174982475 0.13881853174982475 3.095189671373722E-20 glomerular_mesangial_cell_differentiation GO:0072008 12133 5 47 1 36 1 4 false 0.13888888888888903 0.13888888888888903 2.6525761819879548E-6 platelet_activation GO:0030168 12133 203 47 2 863 3 2 false 0.1396310037335863 0.1396310037335863 1.0918730712206789E-203 regulation_of_metabolic_process GO:0019222 12133 4469 47 26 9189 45 2 false 0.1398989922814255 0.1398989922814255 0.0 positive_regulation_of_transferase_activity GO:0051347 12133 445 47 3 2275 7 3 false 0.1402478056449964 0.1402478056449964 0.0 Notch_receptor_processing GO:0007220 12133 17 47 1 3038 27 1 false 0.14115302855840667 0.14115302855840667 2.325698863690895E-45 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 47 3 835 6 2 false 0.1417656058609556 0.1417656058609556 8.0742416973675315E-196 cellular_protein_catabolic_process GO:0044257 12133 409 47 6 3174 28 3 false 0.14223648007313744 0.14223648007313744 0.0 positive_regulation_of_DNA_recombination GO:0045911 12133 13 47 1 260 3 3 false 0.1431489629164187 0.1431489629164187 3.404510615248639E-22 regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900739 12133 24 47 1 315 2 3 false 0.14680012132240666 0.14680012132240666 1.6734366655590734E-36 positive_regulation_of_kinase_activity GO:0033674 12133 438 47 3 1181 4 3 false 0.14690046477455157 0.14690046477455157 0.0 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 47 3 2035 9 3 false 0.14760330502090904 0.14760330502090904 0.0 excretion GO:0007588 12133 50 47 1 1272 4 1 false 0.1483671576196445 0.1483671576196445 4.8139348402185623E-91 ubiquitin-dependent_protein_catabolic_process_via_the_multivesicular_body_sorting_pathway GO:0043162 12133 10 47 1 379 6 3 false 0.14915097071341488 0.14915097071341488 6.689174917849262E-20 regulation_of_protein_kinase_activity GO:0045859 12133 621 47 3 1169 3 3 false 0.1495704253511343 0.1495704253511343 0.0 mesangial_cell_differentiation GO:0072007 12133 6 47 1 40 1 1 false 0.15000000000000094 0.15000000000000094 2.6052657631605334E-7 regulation_of_ion_transmembrane_transporter_activity GO:0032412 12133 73 47 1 485 1 3 false 0.15051546391749993 0.15051546391749993 1.1784649326580688E-88 positive_regulation_of_protein_modification_process GO:0031401 12133 708 47 6 2417 13 3 false 0.15056211610745318 0.15056211610745318 0.0 intracellular_signal_transduction GO:0035556 12133 1813 47 9 3547 13 1 false 0.15125153218494541 0.15125153218494541 0.0 positive_regulation_of_cellular_process GO:0048522 12133 2811 47 17 9694 46 3 false 0.1516788066102854 0.1516788066102854 0.0 DNA_recombination GO:0006310 12133 190 47 3 791 6 1 false 0.15347109068455161 0.15347109068455161 1.2250789605162758E-188 regulation_of_cell_differentiation GO:0045595 12133 872 47 6 6612 28 3 false 0.15463305249302048 0.15463305249302048 0.0 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 47 3 389 6 3 false 0.1548674898395691 0.1548674898395691 8.074632425282073E-93 intracellular_organelle GO:0043229 12133 7958 47 43 9096 46 2 false 0.1556302907615038 0.1556302907615038 0.0 cellular_response_to_peptide GO:1901653 12133 247 47 2 625 2 3 false 0.15580000000000666 0.15580000000000666 2.2359681686760748E-181 organic_substance_metabolic_process GO:0071704 12133 7451 47 44 8027 45 1 false 0.156226868653145 0.156226868653145 0.0 positive_regulation_of_neurological_system_process GO:0031646 12133 51 47 1 1224 4 3 false 0.1567164357739716 0.1567164357739716 1.4877707667450444E-91 intracellular_protein_kinase_cascade GO:0007243 12133 806 47 6 1813 9 1 false 0.15694620260762632 0.15694620260762632 0.0 protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:0001844 12133 25 47 1 305 2 3 false 0.15746333045727867 0.15746333045727867 3.3284741778861134E-37 regulation_of_Rac_protein_signal_transduction GO:0035020 12133 23 47 1 278 2 2 false 0.15889670934732794 0.15889670934732794 4.034778444759645E-34 innate_immune_response GO:0045087 12133 626 47 7 1268 10 2 false 0.1607471850287015 0.1607471850287015 0.0 hippocampus_development GO:0021766 12133 46 47 1 3152 12 4 false 0.16199250783342878 0.16199250783342878 8.889994332374666E-104 cellular_response_to_organic_substance GO:0071310 12133 1347 47 8 1979 9 2 false 0.1631419719476264 0.1631419719476264 0.0 negative_regulation_of_systemic_arterial_blood_pressure GO:0003085 12133 11 47 1 67 1 2 false 0.16417910447761364 0.16417910447761364 7.781717560880856E-13 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 47 13 2643 20 1 false 0.16492253494489786 0.16492253494489786 0.0 M_phase GO:0000279 12133 22 47 1 253 2 1 false 0.16666666666662772 0.16666666666662772 3.8938574183719536E-32 cytoplasmic_stress_granule GO:0010494 12133 29 47 1 5117 32 2 false 0.16675443661796088 0.16675443661796088 2.627932865737447E-77 activation_of_MAPK_activity GO:0000187 12133 158 47 3 286 3 2 false 0.1671675988948046 0.1671675988948046 8.207976102051858E-85 positive_regulation_of_isotype_switching GO:0045830 12133 12 47 1 137 2 5 false 0.16809789609273765 0.16809789609273765 1.7989734568189992E-17 ribose_phosphate_metabolic_process GO:0019693 12133 1207 47 6 3007 10 3 false 0.16819405927706166 0.16819405927706166 0.0 glomerulus_development GO:0032835 12133 48 47 1 3152 12 3 false 0.16845630512020573 0.16845630512020573 2.079589057162791E-107 cell_differentiation_involved_in_kidney_development GO:0061005 12133 40 47 1 2189 10 2 false 0.1687342749346424 0.1687342749346424 2.8675090543885934E-86 monovalent_inorganic_cation_homeostasis GO:0055067 12133 56 47 1 330 1 1 false 0.16969696969696543 0.16969696969696543 9.24814230107908E-65 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 47 5 5051 15 3 false 0.1705288080154276 0.1705288080154276 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 47 3 6813 30 2 false 0.1713073352494537 0.1713073352494537 0.0 protein_binding GO:0005515 12133 6397 47 34 8962 43 1 false 0.17176971044717465 0.17176971044717465 0.0 regulation_of_sodium_ion_transport GO:0002028 12133 37 47 1 215 1 2 false 0.17209302325580766 0.17209302325580766 1.8499074186131244E-42 vasculature_development GO:0001944 12133 441 47 3 2686 9 2 false 0.1721792390845655 0.1721792390845655 0.0 clathrin_vesicle_coat GO:0030125 12133 20 47 1 116 1 3 false 0.1724137931034499 0.1724137931034499 7.110456703810784E-23 ncRNA_metabolic_process GO:0034660 12133 258 47 5 3294 38 1 false 0.17250096938863385 0.17250096938863385 0.0 Rac_protein_signal_transduction GO:0016601 12133 33 47 1 365 2 1 false 0.17287370164083218 0.17287370164083218 1.0734561739608448E-47 respiratory_burst_involved_in_inflammatory_response GO:0002536 12133 4 47 1 23 1 2 false 0.1739130434782608 0.1739130434782608 1.1293054771315566E-4 cytoplasmic_vesicle_part GO:0044433 12133 366 47 4 7185 43 3 false 0.17399788616720085 0.17399788616720085 0.0 nucleoplasm GO:0005654 12133 1443 47 17 2767 27 2 false 0.17468293232189275 0.17468293232189275 0.0 renal_interstitial_cell_differentiation GO:0072071 12133 7 47 1 40 1 1 false 0.17500000000000104 0.17500000000000104 5.363782453565752E-8 RNA-dependent_ATPase_activity GO:0008186 12133 21 47 1 228 2 1 false 0.1760955251564932 0.1760955251564932 4.020483440001667E-30 regulation_of_mitochondrial_outer_membrane_permeabilization GO:1901028 12133 33 47 1 354 2 4 false 0.17799010899312492 0.17799010899312492 3.0911895026883726E-47 ribosome_assembly GO:0042255 12133 16 47 1 417 5 3 false 0.1784708775522256 0.1784708775522256 3.349634512578164E-29 cell_cycle_process GO:0022402 12133 953 47 7 7541 37 2 false 0.17897846570368559 0.17897846570368559 0.0 positive_regulation_of_protein_binding GO:0032092 12133 37 47 1 6397 34 3 false 0.1794148440541567 0.1794148440541567 2.3062856812384995E-98 sodium_channel_regulator_activity GO:0017080 12133 14 47 1 78 1 2 false 0.17948717948717585 0.17948717948717585 9.768201397951623E-16 SH2_domain_binding GO:0042169 12133 31 47 1 486 3 1 false 0.17975785134477879 0.17975785134477879 1.1318841086292139E-49 lymphocyte_activation_involved_in_immune_response GO:0002285 12133 78 47 1 432 1 2 false 0.18055555555552838 0.18055555555552838 5.057484756456232E-88 cellular_membrane_organization GO:0016044 12133 784 47 6 7541 37 2 false 0.18104287819844245 0.18104287819844245 0.0 protein_binding_transcription_factor_activity GO:0000988 12133 488 47 4 10311 47 3 false 0.18127339307272594 0.18127339307272594 0.0 kinesin_complex GO:0005871 12133 20 47 1 110 1 1 false 0.18181818181817921 0.18181818181817921 2.27584542759169E-22 RNA_methyltransferase_activity GO:0008173 12133 23 47 1 126 1 2 false 0.1825396825396866 0.1825396825396866 1.0792211566104033E-25 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 47 2 217 4 1 false 0.18364127079832696 0.18364127079832696 4.514459380304185E-47 ATP-dependent_helicase_activity GO:0008026 12133 98 47 2 228 2 2 false 0.18366952623849817 0.18366952623849817 4.1384935546953996E-67 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 47 4 723 4 2 false 0.18393277883218373 0.18393277883218373 2.0953844092707462E-201 regulation_of_innate_immune_response GO:0045088 12133 226 47 4 868 9 3 false 0.18457989421031873 0.18457989421031873 2.196344369914344E-215 response_to_oxygen_levels GO:0070482 12133 214 47 3 676 5 1 false 0.18491303749934163 0.18491303749934163 1.6255941364061853E-182 positive_regulation_of_B_cell_activation GO:0050871 12133 52 47 1 280 1 3 false 0.18571428571426857 0.18571428571426857 7.083953117162652E-58 MAP_kinase_kinase_kinase_activity GO:0004709 12133 26 47 1 520 4 3 false 0.18599052743674738 0.18599052743674738 1.8429565665115438E-44 regulation_of_steroid_metabolic_process GO:0019218 12133 56 47 1 301 1 2 false 0.18604651162788827 0.18604651162788827 2.659882776337694E-62 nuclear_matrix GO:0016363 12133 81 47 2 2767 27 2 false 0.18616921437825884 0.18616921437825884 2.9785824972298125E-158 protein_catabolic_process GO:0030163 12133 498 47 6 3569 28 2 false 0.1864784284177659 0.1864784284177659 0.0 outer_membrane GO:0019867 12133 112 47 1 4398 8 1 false 0.18660181759216263 0.18660181759216263 7.412183245910406E-226 limbic_system_development GO:0021761 12133 61 47 1 2686 9 2 false 0.187030707747455 0.187030707747455 6.732470891549266E-126 protein_polyubiquitination GO:0000209 12133 163 47 4 548 8 1 false 0.1879738384399298 0.1879738384399298 3.681189236491621E-144 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 47 5 982 5 1 false 0.18860492831538925 0.18860492831538925 2.6984349291053464E-253 RNA_localization GO:0006403 12133 131 47 3 1642 19 1 false 0.18891427649504994 0.18891427649504994 1.0675246049472868E-197 positive_regulation_of_metabolic_process GO:0009893 12133 1872 47 13 8366 45 3 false 0.1893637444558155 0.1893637444558155 0.0 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 47 3 650 6 2 false 0.18976859002774452 0.18976859002774452 6.010278185218431E-162 response_to_osmotic_stress GO:0006970 12133 43 47 1 2681 13 2 false 0.1899588162181031 0.1899588162181031 3.246680302266631E-95 negative_regulation_of_ion_transport GO:0043271 12133 50 47 1 974 4 3 false 0.19033208156814752 0.19033208156814752 4.081641839466338E-85 Cul4B-RING_ubiquitin_ligase_complex GO:0031465 12133 4 47 1 21 1 1 false 0.19047619047619052 0.19047619047619052 1.6708437761069314E-4 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 47 24 8688 45 3 false 0.1906338224979072 0.1906338224979072 0.0 activating_transcription_factor_binding GO:0033613 12133 294 47 3 715 4 1 false 0.19168632231528435 0.19168632231528435 1.6086726333731214E-209 regulation_of_cellular_component_organization GO:0051128 12133 1152 47 8 7336 36 2 false 0.1936891901894511 0.1936891901894511 0.0 Golgi-associated_vesicle_membrane GO:0030660 12133 29 47 1 553 4 3 false 0.19431977401853107 0.19431977401853107 5.3948858906392845E-49 myeloid_cell_homeostasis GO:0002262 12133 111 47 2 1628 12 2 false 0.19486820834089186 0.19486820834089186 2.626378318706563E-175 type_I_interferon_production GO:0032606 12133 71 47 1 362 1 1 false 0.19613259668509953 0.19613259668509953 2.8677775679244762E-77 regulation_of_protein_acetylation GO:1901983 12133 34 47 1 1097 7 2 false 0.1982859922890945 0.1982859922890945 2.1258425781065562E-65 protein_phosphorylated_amino_acid_binding GO:0045309 12133 19 47 2 42 2 1 false 0.19860627177700557 0.19860627177700557 2.238261550776809E-12 postreplication_repair GO:0006301 12133 16 47 1 368 5 1 false 0.20028861513027715 0.20028861513027715 2.574562678585272E-28 muscle_structure_development GO:0061061 12133 413 47 3 3152 12 2 false 0.200714122981634 0.200714122981634 0.0 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 47 1 818 3 2 false 0.20137786697215734 0.20137786697215734 1.6613120232447818E-91 primary_metabolic_process GO:0044238 12133 7288 47 43 8027 45 1 false 0.2031581579121401 0.2031581579121401 0.0 regulation_of_membrane_potential GO:0042391 12133 216 47 2 478 2 1 false 0.20367885055660395 0.20367885055660395 3.2092050959317294E-142 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 47 1 201 1 3 false 0.20398009950248341 0.20398009950248341 9.949481941404742E-44 negative_regulation_of_mRNA_processing GO:0050686 12133 13 47 1 1096 19 3 false 0.20435844617779866 0.20435844617779866 2.031276795679201E-30 regulation_of_cell_junction_assembly GO:1901888 12133 35 47 1 1245 8 3 false 0.20449214823455455 0.20449214823455455 7.812749785355693E-69 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 47 2 195 3 4 false 0.2050416438964213 0.2050416438964213 1.081664723883568E-50 regulation_of_type_I_interferon_production GO:0032479 12133 67 47 1 325 1 2 false 0.2061538461538324 0.2061538461538324 2.788484219003069E-71 cerebral_cortex_development GO:0021987 12133 60 47 1 3152 12 3 false 0.2062889629060164 0.2062889629060164 1.7800361131587683E-128 activation_of_protein_kinase_activity GO:0032147 12133 247 47 3 417 3 1 false 0.20678577619830135 0.20678577619830135 9.475379918718814E-122 blood_vessel_development GO:0001568 12133 420 47 3 3152 12 3 false 0.20787124055468148 0.20787124055468148 0.0 signalosome GO:0008180 12133 32 47 1 4399 32 2 false 0.20900305185533477 0.20900305185533477 7.6195658646057E-82 pore_complex GO:0046930 12133 84 47 1 5051 14 3 false 0.20949882449492838 0.20949882449492838 5.4712090537168384E-185 negative_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043154 12133 63 47 1 1373 5 3 false 0.20959199130720074 0.20959199130720074 1.783777218833555E-110 coated_pit GO:0005905 12133 52 47 1 10213 46 3 false 0.20968980229682588 0.20968980229682588 3.070128605674566E-141 mitotic_spindle_organization GO:0007052 12133 37 47 1 648 4 2 false 0.21001217530366648 0.21001217530366648 3.6765869552528886E-61 positive_regulation_of_histone_acetylation GO:0035066 12133 16 47 1 144 2 4 false 0.2105672105671897 0.2105672105671897 1.4536629180584386E-21 U7_snRNP GO:0005683 12133 7 47 1 93 3 1 false 0.2113496601575085 0.2113496601575085 1.0555624376114707E-10 regulation_of_mitochondrial_membrane_permeability GO:0046902 12133 46 47 1 2152 11 3 false 0.2119861361511031 0.2119861361511031 4.367031159968052E-96 sodium_ion_transmembrane_transporter_activity GO:0015081 12133 67 47 1 316 1 3 false 0.21202531645569045 0.21202531645569045 2.2934303131006308E-70 regulation_of_B_cell_mediated_immunity GO:0002712 12133 30 47 1 140 1 3 false 0.21428571428570842 0.21428571428570842 3.1294479390270554E-31 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 47 2 227 3 2 false 0.21432198874639413 0.21432198874639413 1.1311225924750782E-59 monocyte_chemotaxis GO:0002548 12133 23 47 1 107 1 1 false 0.21495327102804263 0.21495327102804263 6.985599683738772E-24 clathrin-coated_endocytic_vesicle GO:0045334 12133 31 47 1 272 2 2 false 0.2153245061862137 0.2153245061862137 1.6415618681542047E-41 nucleobase-containing_compound_transport GO:0015931 12133 135 47 3 1584 19 2 false 0.21617478551193936 0.21617478551193936 1.0378441909200412E-199 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 47 1 148 1 3 false 0.21621621621620796 0.21621621621620796 3.492638478654734E-33 ribosomal_small_subunit_assembly GO:0000028 12133 6 47 1 128 5 3 false 0.2164991321649225 0.2164991321649225 1.8437899825856603E-10 negative_regulation_of_cysteine-type_endopeptidase_activity GO:2000117 12133 66 47 1 303 1 3 false 0.21782178217821413 0.21782178217821413 1.924144504065005E-68 vasculogenesis GO:0001570 12133 62 47 1 3056 12 4 false 0.21839625752952163 0.21839625752952163 4.885889713794216E-131 ERBB_signaling_pathway GO:0038127 12133 199 47 3 586 5 1 false 0.2184014332158294 0.2184014332158294 2.435227003721618E-162 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 47 2 198 3 2 false 0.21855350354261407 0.21855350354261407 2.9049351003528108E-52 regulation_of_dephosphorylation GO:0035303 12133 87 47 1 1455 4 2 false 0.2187710435183987 0.2187710435183987 1.9687002630039133E-142 mitochondrial_outer_membrane_permeabilization GO:0097345 12133 37 47 1 319 2 3 false 0.21884426568875764 0.21884426568875764 2.7662883808425E-49 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 47 1 594 3 3 false 0.21942681797238892 0.21942681797238892 7.186758669481106E-71 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 47 9 5447 42 3 false 0.220193969217342 0.220193969217342 0.0 B_cell_activation_involved_in_immune_response GO:0002312 12133 42 47 1 189 1 2 false 0.22222222222221422 0.22222222222221422 4.7631707498717995E-43 regulation_of_response_to_stress GO:0080134 12133 674 47 5 3466 17 2 false 0.22277675459864457 0.22277675459864457 0.0 negative_regulation_of_viral_reproduction GO:0048525 12133 28 47 1 2903 26 4 false 0.22360127181932982 0.22360127181932982 3.8119989558045655E-68 cell-substrate_junction GO:0030055 12133 133 47 1 588 1 1 false 0.22619047619048865 0.22619047619048865 7.571970094553597E-136 negative_regulation_of_striated_muscle_cell_differentiation GO:0051154 12133 17 47 1 208 3 3 false 0.22670024677729736 0.22670024677729736 2.72756232006883E-25 negative_regulation_of_biological_process GO:0048519 12133 2732 47 15 10446 47 2 false 0.22773571385910263 0.22773571385910263 0.0 protein_complex_subunit_organization GO:0071822 12133 989 47 16 1256 18 1 false 0.22839327389656788 0.22839327389656788 2.2763776011987297E-281 positive_regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033148 12133 8 47 1 35 1 3 false 0.22857142857142917 0.22857142857142917 4.248842827655879E-8 basal_transcription_machinery_binding GO:0001098 12133 464 47 4 6397 34 1 false 0.2303954449239644 0.2303954449239644 0.0 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 47 2 1130 6 2 false 0.23056623708079244 0.23056623708079244 2.620015602340521E-209 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 47 1 953 7 4 false 0.23107869174991114 0.23107869174991114 1.0482452124052062E-64 positive_regulation_of_response_to_DNA_damage_stimulus GO:2001022 12133 44 47 1 3212 19 4 false 0.23111618490378955 0.23111618490378955 1.7987290458431554E-100 negative_regulation_of_translation GO:0017148 12133 61 47 2 1470 22 4 false 0.23113639308031525 0.23113639308031525 1.1152524521517982E-109 ephrin_receptor_signaling_pathway GO:0048013 12133 30 47 1 586 5 1 false 0.2317830595474496 0.2317830595474496 5.184030943639595E-51 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 47 2 1663 11 2 false 0.23285026685308416 0.23285026685308416 7.181952736648417E-207 Cul4-RING_ubiquitin_ligase_complex GO:0080008 12133 21 47 1 90 1 1 false 0.23333333333333656 0.23333333333333656 5.884575201651408E-21 negative_regulation_of_neurogenesis GO:0050768 12133 81 47 1 956 3 3 false 0.23347894124022173 0.23347894124022173 7.263496623051508E-120 regulation_of_transferase_activity GO:0051338 12133 667 47 3 2708 7 2 false 0.23576329910108348 0.23576329910108348 0.0 Rho_protein_signal_transduction GO:0007266 12133 178 47 2 365 2 1 false 0.23713683576697228 0.23713683576697228 3.561371803691081E-109 regulation_of_transporter_activity GO:0032409 12133 88 47 1 2973 9 3 false 0.23722323677647184 0.23722323677647184 1.555650039308817E-171 regulation_of_viral_genome_replication GO:0045069 12133 43 47 1 181 1 3 false 0.23756906077349124 0.23756906077349124 1.1493804978494703E-42 response_to_DNA_damage_stimulus GO:0006974 12133 570 47 5 1124 7 1 false 0.23768394728372022 0.23768394728372022 0.0 negative_regulation_of_mitosis GO:0045839 12133 43 47 1 656 4 5 false 0.2380142090566087 0.2380142090566087 1.8426541499010044E-68 negative_regulation_of_protein_complex_assembly GO:0031333 12133 63 47 1 954 4 3 false 0.23945713431490256 0.23945713431490256 3.124938390294621E-100 nuclear_speck GO:0016607 12133 147 47 4 272 5 1 false 0.23986830806027115 0.23986830806027115 6.6218564870724965E-81 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 47 3 252 3 2 false 0.24007209258204606 0.24007209258204606 5.925442745937436E-72 Golgi-associated_vesicle GO:0005798 12133 52 47 1 975 5 2 false 0.24013982497964836 0.24013982497964836 1.201522273090165E-87 regulation_of_protein_catabolic_process GO:0042176 12133 150 47 2 1912 12 3 false 0.2414239288505498 0.2414239288505498 1.3832082048306078E-227 positive_regulation_of_molecular_function GO:0044093 12133 1303 47 8 10257 47 2 false 0.2414929795473007 0.2414929795473007 0.0 organelle_fission GO:0048285 12133 351 47 3 2031 10 1 false 0.24181901609570505 0.24181901609570505 0.0 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 47 9 3547 13 1 false 0.24285272722595078 0.24285272722595078 0.0 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 47 3 1256 18 1 false 0.24316079938639185 0.24316079938639185 3.1457660386089413E-171 nuclear_periphery GO:0034399 12133 97 47 2 2767 27 2 false 0.2440133406248156 0.2440133406248156 7.041791399430774E-182 DNA-dependent_transcription,_initiation GO:0006352 12133 225 47 4 2751 31 2 false 0.24482431261474702 0.24482431261474702 0.0 post-embryonic_development GO:0009791 12133 81 47 1 4373 15 3 false 0.24489681595494936 0.24489681595494936 1.5270071764931075E-174 positive_regulation_of_lyase_activity GO:0051349 12133 64 47 1 1165 5 3 false 0.24648882758154175 0.24648882758154175 4.208539259642897E-107 transition_metal_ion_transport GO:0000041 12133 60 47 1 455 2 1 false 0.24659921576230573 0.24659921576230573 1.613674695371724E-76 circulatory_system_process GO:0003013 12133 307 47 2 1272 4 1 false 0.24703161066527038 0.24703161066527038 1.974873217376429E-304 regulation_of_action_potential_in_neuron GO:0019228 12133 80 47 1 605 2 2 false 0.2471676427126179 0.2471676427126179 4.887986277192938E-102 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 47 2 299 2 2 false 0.24749163879601563 0.24749163879601563 2.1331125641940734E-89 extracellular_membrane-bounded_organelle GO:0065010 12133 59 47 1 7284 35 2 false 0.2482275937466312 0.2482275937466312 2.3146567535480854E-148 regulation_of_B_cell_activation GO:0050864 12133 78 47 1 314 1 2 false 0.24840764331208454 0.24840764331208454 6.891800701996175E-76 RNA_methylation GO:0001510 12133 25 47 1 188 2 2 false 0.24889065877798863 0.24889065877798863 1.1533363650630908E-31 positive_regulation_of_cell_division GO:0051781 12133 51 47 1 3061 17 3 false 0.24902462635148778 0.24902462635148778 3.9220691729316426E-112 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 47 2 254 3 3 false 0.24964542475661802 0.24964542475661802 3.7262148804586973E-69 UBC13-MMS2_complex GO:0031372 12133 2 47 1 8 1 1 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 UBC13-UEV1A_complex GO:0035370 12133 2 47 1 8 1 1 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 leukocyte_activation_involved_in_immune_response GO:0002366 12133 119 47 1 475 1 2 false 0.2505263157894802 0.2505263157894802 1.7839978104873963E-115 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 47 5 7293 35 3 false 0.2527468888347769 0.2527468888347769 0.0 protein_insertion_into_mitochondrial_membrane GO:0051204 12133 25 47 1 1644 19 4 false 0.25380417888686474 0.25380417888686474 7.460154269678152E-56 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 47 1 1642 11 2 false 0.253833878430629 0.253833878430629 5.767987369966462E-86 response_to_peptide_hormone_stimulus GO:0043434 12133 313 47 2 619 2 2 false 0.2552817729818599 0.2552817729818599 1.4916788604957572E-185 positive_regulation_of_histone_H3-K4_methylation GO:0051571 12133 10 47 1 39 1 3 false 0.2564102564102556 0.2564102564102556 1.5729567312509424E-9 regulation_of_peptidyl-lysine_acetylation GO:2000756 12133 33 47 1 128 1 2 false 0.25781249999999833 0.25781249999999833 2.3260819461485724E-31 positive_regulation_of_immune_effector_process GO:0002699 12133 87 47 2 706 8 3 false 0.2578280136379325 0.2578280136379325 7.573271162497966E-114 mitochondrial_outer_membrane GO:0005741 12133 96 47 1 372 1 2 false 0.25806451612902936 0.25806451612902936 1.1824719222700171E-91 negative_regulation_of_catalytic_activity GO:0043086 12133 588 47 3 4970 15 3 false 0.25814205482412866 0.25814205482412866 0.0 snRNA_metabolic_process GO:0016073 12133 15 47 1 258 5 1 false 0.2605971279669072 0.2605971279669072 1.3254371174076553E-24 regulation_of_muscle_organ_development GO:0048634 12133 106 47 1 1105 3 2 false 0.26127240214967756 0.26127240214967756 5.2870889259577626E-151 channel_regulator_activity GO:0016247 12133 66 47 1 10257 47 2 false 0.26220511970484295 0.26220511970484295 1.2576121117294417E-172 apoptotic_mitochondrial_changes GO:0008637 12133 87 47 1 1476 5 2 false 0.26227456280628025 0.26227456280628025 5.447605955370739E-143 nephron_development GO:0072006 12133 79 47 1 3152 12 3 false 0.2629756097341407 0.2629756097341407 9.804100439545243E-160 extracellular_organelle GO:0043230 12133 59 47 1 8358 43 2 false 0.26316306314350985 0.26316306314350985 6.7158083402639515E-152 positive_regulation_of_cyclase_activity GO:0031281 12133 63 47 1 1064 5 3 false 0.2634459753510187 0.2634459753510187 2.5891490792503797E-103 positive_regulation_of_DNA_repair GO:0045739 12133 26 47 1 440 5 4 false 0.26359953522455065 0.26359953522455065 1.5959457492821637E-42 protein_tetramerization GO:0051262 12133 76 47 1 288 1 1 false 0.26388888888887596 0.26388888888887596 1.240191410365077E-71 apoptotic_signaling_pathway GO:0097190 12133 305 47 2 3954 13 2 false 0.2650623843488469 0.2650623843488469 0.0 methyltransferase_complex GO:0034708 12133 62 47 1 9248 46 2 false 0.26669037546442964 0.26669037546442964 4.919625587422917E-161 regulation_of_primary_metabolic_process GO:0080090 12133 3921 47 25 7507 43 2 false 0.266770669702598 0.266770669702598 0.0 nucleus_organization GO:0006997 12133 62 47 1 2031 10 1 false 0.26708439102181913 0.26708439102181913 6.73570952581451E-120 negative_regulation_of_nuclear_division GO:0051784 12133 43 47 1 436 3 3 false 0.26820422283667583 0.26820422283667583 1.634686522119006E-60 histone_ubiquitination GO:0016574 12133 31 47 1 813 8 2 false 0.26830012638930334 0.26830012638930334 8.990376944152675E-57 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 47 5 3605 30 4 false 0.2700729722636917 0.2700729722636917 0.0 regulation_of_protein_metabolic_process GO:0051246 12133 1388 47 11 5563 36 3 false 0.27198072641680004 0.27198072641680004 0.0 regulation_of_cell_division GO:0051302 12133 75 47 1 6427 27 2 false 0.27208898545977905 0.27208898545977905 9.599183496643589E-177 membrane_coat GO:0030117 12133 66 47 1 7525 36 4 false 0.2723124221489625 0.2723124221489625 1.024710613883824E-163 histone_deacetylase_binding GO:0042826 12133 62 47 1 1005 5 1 false 0.27315273897610554 0.27315273897610554 1.577479125629217E-100 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 47 3 5157 21 3 false 0.27335206108980925 0.27335206108980925 0.0 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 47 1 278 1 3 false 0.27338129496405167 0.27338129496405167 2.8121052478162137E-70 regulation_of_biological_quality GO:0065008 12133 2082 47 11 6908 30 1 false 0.2749012606583289 0.2749012606583289 0.0 pre-mRNA_binding GO:0036002 12133 10 47 1 763 24 1 false 0.2749631472141094 0.2749631472141094 5.757557985229243E-23 binding GO:0005488 12133 8962 47 43 10257 47 1 false 0.2755316160995914 0.2755316160995914 0.0 regulation_of_protein_complex_assembly GO:0043254 12133 185 47 2 1610 9 3 false 0.27706672288588485 0.27706672288588485 1.34790682725651E-248 mRNA_3'-splice_site_recognition GO:0000389 12133 5 47 1 18 1 1 false 0.2777777777777786 0.2777777777777786 1.1671335200746984E-4 anatomical_structure_development GO:0048856 12133 3099 47 12 3447 12 1 false 0.2782451061255065 0.2782451061255065 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 47 2 341 5 4 false 0.2791015290944245 0.2791015290944245 3.257446469032824E-75 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 47 9 5032 42 4 false 0.2802281716853596 0.2802281716853596 0.0 regulation_of_protein_modification_process GO:0031399 12133 1001 47 7 2566 14 2 false 0.28026754342751153 0.28026754342751153 0.0 positive_regulation_of_phosphorylation GO:0042327 12133 563 47 3 1487 5 3 false 0.2809153047013332 0.2809153047013332 0.0 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 47 2 506 3 3 false 0.2810733247237542 0.2810733247237542 1.5079927652081954E-141 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 47 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 47 11 6103 44 3 false 0.28292300931117376 0.28292300931117376 0.0 positive_regulation_of_histone_methylation GO:0031062 12133 16 47 1 104 2 3 false 0.28528752800596324 0.28528752800596324 3.7681406369703167E-19 regulation_of_lyase_activity GO:0051339 12133 117 47 1 1793 5 2 false 0.2866556248431259 0.2866556248431259 4.0773224530305873E-187 regulation_of_steroid_biosynthetic_process GO:0050810 12133 42 47 1 146 1 3 false 0.2876712328767199 0.2876712328767199 1.231507741439357E-37 nucleoside_phosphate_binding GO:1901265 12133 1998 47 18 4407 35 2 false 0.288053538761343 0.288053538761343 0.0 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 47 1 2474 13 3 false 0.2893419931199271 0.2893419931199271 1.917782059478808E-128 negative_regulation_of_viral_genome_replication GO:0045071 12133 27 47 1 93 1 4 false 0.2903225806451571 0.2903225806451571 5.123998834104114E-24 endocytic_vesicle GO:0030139 12133 152 47 2 712 5 1 false 0.29032798075282107 0.29032798075282107 1.2528026489004738E-159 negative_regulation_of_protein_modification_process GO:0031400 12133 328 47 3 2431 14 3 false 0.2903319835976721 0.2903319835976721 0.0 regulation_of_defense_response GO:0031347 12133 387 47 4 1253 9 2 false 0.29035127573263514 0.29035127573263514 0.0 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 47 2 415 3 3 false 0.29035582270131366 0.29035582270131366 9.462933237946419E-117 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 47 1 415 3 1 false 0.29192800256720985 0.29192800256720985 2.1919403735850567E-61 potassium_ion_transmembrane_transporter_activity GO:0015079 12133 92 47 1 315 1 3 false 0.2920634920635222 0.2920634920635222 4.7759735730125735E-82 negative_regulation_of_cellular_process GO:0048523 12133 2515 47 14 9689 46 3 false 0.29299950844070155 0.29299950844070155 0.0 male_sex_differentiation GO:0046661 12133 105 47 1 3074 10 2 false 0.2939458133700586 0.2939458133700586 4.0305150218166505E-198 regulation_of_Schwann_cell_proliferation GO:0010624 12133 5 47 1 17 1 2 false 0.2941176470588238 0.2941176470588238 1.6160310277957323E-4 response_to_biotic_stimulus GO:0009607 12133 494 47 3 5200 20 1 false 0.2945543686380262 0.2945543686380262 0.0 positive_regulation_of_binding GO:0051099 12133 73 47 1 9050 43 3 false 0.29465712727037446 0.29465712727037446 8.738239425278628E-184 protein_complex_localization GO:0031503 12133 29 47 1 1434 17 1 false 0.2948116280385834 0.2948116280385834 3.39152835029198E-61 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 47 4 309 5 2 false 0.29500520490392124 0.29500520490392124 7.558729588417702E-91 smooth_muscle_contraction GO:0006939 12133 65 47 1 220 1 1 false 0.29545454545454364 0.29545454545454364 1.7294918023527772E-57 pallium_development GO:0021543 12133 89 47 1 3099 12 2 false 0.2955261758607715 0.2955261758607715 1.1299570779339424E-174 regulation_of_cyclase_activity GO:0031279 12133 115 47 1 1700 5 2 false 0.29576755239868063 0.29576755239868063 4.764508019192963E-182 regulation_of_kinase_activity GO:0043549 12133 654 47 3 1335 4 3 false 0.2971945445039263 0.2971945445039263 0.0 regulation_of_DNA_metabolic_process GO:0051052 12133 188 47 2 4316 25 3 false 0.297657670535128 0.297657670535128 0.0 ensheathment_of_neurons GO:0007272 12133 72 47 1 7590 37 3 false 0.29777863044705344 0.29777863044705344 3.5999955823156774E-176 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 47 1 222 2 3 false 0.29864253393661766 0.29864253393661766 2.5456303013282065E-42 methylation GO:0032259 12133 195 47 2 8027 45 1 false 0.29895135924906313 0.29895135924906313 0.0 negative_regulation_of_immune_response GO:0050777 12133 48 47 1 1512 11 4 false 0.2995748497930993 0.2995748497930993 6.35137019676024E-92 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 47 1 385 3 3 false 0.2997249160761194 0.2997249160761194 4.6200993055738E-58 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 47 5 3910 30 3 false 0.3015485981825893 0.3015485981825893 0.0 negative_regulation_of_response_to_external_stimulus GO:0032102 12133 105 47 1 1508 5 3 false 0.303268143359365 0.303268143359365 8.164414473234676E-165 regulation_of_neurological_system_process GO:0031644 12133 172 47 1 1040 2 2 false 0.30355001110540974 0.30355001110540974 8.112526166227745E-202 clathrin-coated_endocytic_vesicle_membrane GO:0030669 12133 26 47 1 157 2 3 false 0.3046709129511338 0.3046709129511338 2.9127380680410067E-30 endocytic_vesicle_membrane GO:0030666 12133 97 47 2 352 4 2 false 0.3050858724211628 0.3050858724211628 2.1109282121886535E-89 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 47 6 2807 10 3 false 0.30512787582699175 0.30512787582699175 0.0 positive_regulation_of_transcription_factor_import_into_nucleus GO:0042993 12133 29 47 1 95 1 3 false 0.3052631578947292 0.3052631578947292 4.6592240238436785E-25 negative_regulation_of_immune_effector_process GO:0002698 12133 45 47 1 518 4 3 false 0.3055441016604462 0.3055441016604462 6.135357945972138E-66 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 47 1 206 1 2 false 0.3058252427184593 0.3058252427184593 1.364605297408496E-54 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 47 2 220 3 1 false 0.3060084316839271 0.3060084316839271 2.4407604211478482E-62 response_to_organic_substance GO:0010033 12133 1783 47 8 2369 9 1 false 0.30621791345533034 0.30621791345533034 0.0 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 47 2 442 2 3 false 0.3117246898760163 0.3117246898760163 4.945935388068452E-131 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 47 3 3842 18 3 false 0.312320965856299 0.312320965856299 0.0 regulation_of_DNA_recombination GO:0000018 12133 38 47 1 324 3 2 false 0.31304889105398015 0.31304889105398015 1.9894741609704344E-50 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 47 2 759 9 3 false 0.3133642261168991 0.3133642261168991 1.1458874617943115E-123 transferrin_transport GO:0033572 12133 24 47 1 1099 17 2 false 0.31487315596304116 0.31487315596304116 8.291143924248354E-50 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 47 2 53 2 2 false 0.31567489114658837 0.31567489114658837 1.6040955778771873E-15 regulation_of_MAP_kinase_activity GO:0043405 12133 268 47 3 533 4 3 false 0.3160343858982104 0.3160343858982104 1.0382438249699724E-159 transferase_activity,_transferring_one-carbon_groups GO:0016741 12133 130 47 1 1779 5 1 false 0.31603993646737805 0.31603993646737805 2.4341608753326182E-201 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 47 1 1679 6 3 false 0.31643635942987813 0.31643635942987813 1.5952227787322578E-167 cyclase_activity GO:0009975 12133 123 47 1 4901 15 1 false 0.31737586287957786 0.31737586287957786 7.077862449152851E-249 sodium_ion_transport GO:0006814 12133 95 47 1 545 2 2 false 0.3185037776579273 0.3185037776579273 6.918862196703055E-109 mRNA_binding GO:0003729 12133 91 47 4 763 24 1 false 0.31864284794399267 0.31864284794399267 1.7788235024198917E-120 sodium_ion_transmembrane_transport GO:0035725 12133 68 47 1 565 3 2 false 0.31984590445849154 0.31984590445849154 1.2033655972436562E-89 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 47 2 202 11 1 false 0.31988072717957183 0.31988072717957183 5.801734415928739E-29 cell-cell_junction_assembly GO:0007043 12133 58 47 1 181 1 2 false 0.3204419889502846 0.3204419889502846 7.851737058026464E-49 negative_regulation_of_endopeptidase_activity GO:0010951 12133 152 47 1 474 1 3 false 0.3206751054852057 0.3206751054852057 1.8080345918982332E-128 localization_within_membrane GO:0051668 12133 37 47 1 1845 19 1 false 0.32078117025618796 0.32078117025618796 2.8489513256034824E-78 metallopeptidase_activity GO:0008237 12133 103 47 1 586 2 1 false 0.3208891222543883 0.3208891222543883 1.108136232226785E-117 immunoglobulin_production_involved_in_immunoglobulin_mediated_immune_response GO:0002381 12133 37 47 1 115 1 2 false 0.3217391304347844 0.3217391304347844 5.328533934457324E-31 response_to_endogenous_stimulus GO:0009719 12133 982 47 5 5200 20 1 false 0.3219701829890776 0.3219701829890776 0.0 regulation_of_immunoglobulin_mediated_immune_response GO:0002889 12133 29 47 1 90 1 2 false 0.322222222222227 0.322222222222227 3.0207008278323007E-24 single-stranded_DNA_binding GO:0003697 12133 58 47 1 179 1 1 false 0.32402234636869975 0.32402234636869975 1.7047154028422047E-48 macromolecule_methylation GO:0043414 12133 149 47 2 5645 44 3 false 0.3243370163191028 0.3243370163191028 2.745935058350772E-298 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 47 2 207 3 2 false 0.32496096256869944 0.32496096256869944 2.976076769798144E-59 regulation_of_cellular_response_to_stress GO:0080135 12133 270 47 2 6503 28 3 false 0.3251088252062593 0.3251088252062593 0.0 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 47 1 2578 12 4 false 0.3253467015242574 0.3253467015242574 1.0942419479084622E-158 regulation_of_immunoglobulin_production GO:0002637 12133 29 47 1 89 1 2 false 0.32584269662921084 0.32584269662921084 4.456771713195185E-24 extracellular_vesicular_exosome GO:0070062 12133 58 47 1 763 5 2 false 0.3272515636654442 0.3272515636654442 1.4131645972383266E-88 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 47 3 803 7 1 false 0.32755577377381506 0.32755577377381506 7.141936114023743E-209 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 47 1 591 5 3 false 0.3279262295619928 0.3279262295619928 1.267222544612779E-68 regulation_of_cell_cycle GO:0051726 12133 659 47 4 6583 29 2 false 0.32957462000612603 0.32957462000612603 0.0 negative_regulation_of_developmental_process GO:0051093 12133 463 47 3 4566 20 3 false 0.3310269824264721 0.3310269824264721 0.0 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 47 1 242 2 2 false 0.3311957751791627 0.3311957751791627 2.220259827778367E-49 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 47 4 5027 31 3 false 0.3314352951451461 0.3314352951451461 0.0 negative_regulation_of_cell_differentiation GO:0045596 12133 381 47 3 3552 19 4 false 0.33387146234523535 0.33387146234523535 0.0 neuron_migration GO:0001764 12133 89 47 1 1360 6 2 false 0.3342617650188366 0.3342617650188366 4.085890514650152E-142 response_to_ionizing_radiation GO:0010212 12133 98 47 1 293 1 1 false 0.3344709897611002 0.3344709897611002 1.6270830108212225E-80 anchoring_junction GO:0070161 12133 197 47 1 588 1 1 false 0.3350340136054925 0.3350340136054925 4.1212451424432254E-162 somatic_diversification_of_immune_receptors GO:0002200 12133 54 47 1 1618 12 2 false 0.33551656665297225 0.33551656665297225 2.9301103973458922E-102 regulation_of_cell_cycle_arrest GO:0071156 12133 89 47 1 481 2 2 false 0.33613998614007884 0.33613998614007884 1.91357850692127E-99 positive_regulation_of_ion_transport GO:0043270 12133 86 47 1 1086 5 3 false 0.33853638014963144 0.33853638014963144 6.3756507891276546E-130 single-organism_process GO:0044699 12133 8052 47 38 10446 47 1 false 0.3387751666269052 0.3387751666269052 0.0 anion_binding GO:0043168 12133 2280 47 9 4448 15 1 false 0.33879943809297036 0.33879943809297036 0.0 negative_regulation_of_multi-organism_process GO:0043901 12133 51 47 1 3360 27 3 false 0.3393837417042609 0.3393837417042609 3.258164733926273E-114 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 47 4 5830 25 3 false 0.3394945931533733 0.3394945931533733 0.0 regulation_of_histone_acetylation GO:0035065 12133 31 47 1 166 2 3 false 0.3395399780942128 0.3395399780942128 2.4571391045681945E-34 protein_serine/threonine_kinase_activity GO:0004674 12133 709 47 3 1014 3 1 false 0.3414058777627787 0.3414058777627787 1.8231541307779663E-268 mitochondrial_membrane_organization GO:0007006 12133 62 47 1 924 6 2 false 0.3415806587727505 0.3415806587727505 3.431124286579491E-98 rRNA_metabolic_process GO:0016072 12133 107 47 3 258 5 1 false 0.3420037365891129 0.3420037365891129 1.860360860420455E-75 response_to_cytokine_stimulus GO:0034097 12133 461 47 3 1783 8 1 false 0.34274496240523666 0.34274496240523666 0.0 vesicle_coat GO:0030120 12133 38 47 1 381 4 3 false 0.34428677945603126 0.34428677945603126 2.9673810590707202E-53 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 47 1 1209 6 3 false 0.3444702493631746 0.3444702493631746 1.376514335843937E-129 protein_export_from_nucleus GO:0006611 12133 46 47 1 2428 22 3 false 0.34469281705908994 0.34469281705908994 1.6048237175829586E-98 tissue_migration GO:0090130 12133 131 47 1 4095 13 1 false 0.34511857538926366 0.34511857538926366 4.3202440607580954E-251 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 47 2 859 6 3 false 0.34521303752135896 0.34521303752135896 4.662302019201105E-186 peptidyl-serine_phosphorylation GO:0018105 12133 121 47 1 1201 4 2 false 0.3464491110452555 0.3464491110452555 1.0029038835537004E-169 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 47 1 230 2 4 false 0.3466869185493838 0.3466869185493838 2.6271911283291635E-48 RNA_stabilization GO:0043489 12133 22 47 2 37 2 1 false 0.3468468468468479 0.3468468468468479 1.0678969112465738E-10 proteolysis GO:0006508 12133 732 47 7 3431 27 1 false 0.3492701134980515 0.3492701134980515 0.0 cellular_component GO:0005575 12133 10701 47 46 11221 47 1 false 0.35246387099276283 0.35246387099276283 0.0 steroid_hormone_receptor_binding GO:0035258 12133 62 47 2 104 2 1 false 0.3530619865571091 0.3530619865571091 4.2931773052216616E-30 regulation_of_mRNA_processing GO:0050684 12133 49 47 1 3175 28 3 false 0.35426903749583094 0.35426903749583094 2.292701139367024E-109 regulation_of_ion_homeostasis GO:2000021 12133 124 47 1 630 2 2 false 0.35516188457374487 0.35516188457374487 4.993626171436977E-135 insulin_receptor_signaling_pathway GO:0008286 12133 151 47 2 617 5 2 false 0.35604045959913444 0.35604045959913444 2.0667953594506098E-148 regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033146 12133 20 47 1 56 1 2 false 0.35714285714286187 0.35714285714286187 1.2728904491493287E-15 cytoplasmic_vesicle GO:0031410 12133 764 47 5 8540 44 3 false 0.35789676214174126 0.35789676214174126 0.0 protein_insertion_into_membrane GO:0051205 12133 32 47 1 1452 20 3 false 0.3615275112469267 0.3615275112469267 2.4360077014496946E-66 single-stranded_RNA_binding GO:0003727 12133 40 47 2 763 24 1 false 0.3619407740528288 0.3619407740528288 1.1547828689277465E-67 MAP_kinase_activity GO:0004707 12133 277 47 3 520 4 2 false 0.36245039965351483 0.36245039965351483 2.5282679507054518E-155 small_ribosomal_subunit GO:0015935 12133 60 47 7 132 13 1 false 0.36265753010460083 0.36265753010460083 4.556510204279982E-39 negative_regulation_of_Schwann_cell_proliferation GO:0010626 12133 4 47 1 11 1 3 false 0.36363636363636415 0.36363636363636415 0.003030303030303028 regulation_of_histone_H3-K4_methylation GO:0051569 12133 16 47 1 44 1 2 false 0.3636363636363643 0.3636363636363643 2.3997227499672215E-12 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 47 1 1402 8 4 false 0.36432224368439425 0.36432224368439425 6.104501177954134E-129 positive_regulation_of_inflammatory_response GO:0050729 12133 58 47 1 543 4 4 false 0.36438940452405766 0.36438940452405766 1.3309637222630526E-79 cellular_potassium_ion_transport GO:0071804 12133 92 47 1 7541 37 2 false 0.36572297899530837 0.36572297899530837 4.105440908779901E-215 peptidyl-serine_modification GO:0018209 12133 127 47 1 623 2 1 false 0.366409810428807 0.366409810428807 3.781982241942545E-136 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 47 1 286 1 3 false 0.36713286713287985 0.36713286713287985 4.516187028693684E-81 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 47 2 5033 21 3 false 0.3681357520555207 0.3681357520555207 0.0 Schwann_cell_proliferation GO:0014010 12133 7 47 1 19 1 1 false 0.3684210526315784 0.3684210526315784 1.9845995078193256E-5 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 47 3 673 4 2 false 0.36852591405447754 0.36852591405447754 4.9348138289436974E-201 receptor_internalization GO:0031623 12133 54 47 1 2372 20 3 false 0.3702618419139019 0.3702618419139019 2.350294022700988E-111 histone_methyltransferase_complex GO:0035097 12133 60 47 1 807 6 2 false 0.37189689920773605 0.37189689920773605 3.052234764972827E-92 regulation_of_histone_methylation GO:0031060 12133 27 47 1 130 2 2 false 0.3735241502683365 0.3735241502683365 1.667447080919269E-28 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 47 2 217 2 2 false 0.37455197132611834 0.37455197132611834 2.2668758893633536E-62 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 47 2 1631 10 2 false 0.3757726885182071 0.3757726885182071 3.3133814045702313E-271 potassium_ion_transport GO:0006813 12133 115 47 1 545 2 2 false 0.37779951430121167 0.37779951430121167 2.5935886393871475E-121 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 47 3 1398 8 2 false 0.37817550442676395 0.37817550442676395 0.0 regulation_of_DNA_repair GO:0006282 12133 46 47 1 508 5 3 false 0.3790812233625401 0.3790812233625401 1.525242689490639E-66 regulation_of_cell_shape GO:0008360 12133 91 47 1 2150 11 2 false 0.379268049711057 0.379268049711057 5.225328409063172E-163 SH3/SH2_adaptor_activity GO:0005070 12133 48 47 1 126 1 2 false 0.38095238095239137 0.38095238095239137 5.926155314091347E-36 snRNA_binding GO:0017069 12133 15 47 1 763 24 1 false 0.3836431986323491 0.3836431986323491 8.685184804619145E-32 signaling_adaptor_activity GO:0035591 12133 65 47 1 839 6 2 false 0.38451289720940335 0.38451289720940335 9.48818477040309E-99 negative_regulation_of_cytokine_production GO:0001818 12133 114 47 1 529 2 3 false 0.38488142292488925 0.38488142292488925 4.407958658606205E-119 negative_regulation_of_defense_response GO:0031348 12133 72 47 1 1505 10 3 false 0.38843640170645904 0.38843640170645904 5.674310231559274E-125 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 47 2 599 5 2 false 0.3892613508432296 0.3892613508432296 1.7219296535416308E-148 negative_regulation_of_cell_development GO:0010721 12133 106 47 1 1346 6 3 false 0.3892761999236762 0.3892761999236762 1.6785551446261856E-160 negative_regulation_of_signal_transduction GO:0009968 12133 571 47 3 3588 14 5 false 0.38972904349214815 0.38972904349214815 0.0 membrane_invagination GO:0010324 12133 411 47 4 784 6 1 false 0.3897424263544369 0.3897424263544369 8.658368437912315E-235 nucleotide_binding GO:0000166 12133 1997 47 18 2103 18 2 false 0.3926553564122497 0.3926553564122497 1.0169073992212018E-181 regulation_of_lipid_biosynthetic_process GO:0046890 12133 85 47 1 3279 19 3 false 0.39372261306481593 0.39372261306481593 1.2266874982723732E-170 transcription_coactivator_activity GO:0003713 12133 264 47 3 478 4 2 false 0.39415523749414827 0.39415523749414827 4.798051856605128E-142 trans-Golgi_network GO:0005802 12133 103 47 1 7259 35 1 false 0.3942970035912934 0.3942970035912934 4.3774465508031144E-234 regulation_of_tube_size GO:0035150 12133 101 47 1 256 1 1 false 0.39453124999999944 0.39453124999999944 5.262447585157191E-74 gliogenesis GO:0042063 12133 145 47 1 940 3 1 false 0.39540502378484144 0.39540502378484144 7.8288038403024E-175 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 47 1 162 2 5 false 0.39613526570044455 0.39613526570044455 7.1760328941400225E-37 spindle_checkpoint GO:0031577 12133 45 47 1 202 2 1 false 0.3967784838184953 0.3967784838184953 4.3818533729449334E-46 B_cell_activation GO:0042113 12133 160 47 1 403 1 1 false 0.3970223325061876 0.3970223325061876 6.533922499780693E-117 mRNA_splice_site_selection GO:0006376 12133 18 47 1 117 3 2 false 0.3970360973359451 0.3970360973359451 1.505085052005422E-21 NF-kappaB_import_into_nucleus GO:0042348 12133 34 47 1 220 3 2 false 0.3971917236966783 0.3971917236966783 9.912199511410154E-41 epithelial_cell_development GO:0002064 12133 164 47 1 1381 4 2 false 0.397256037173805 0.397256037173805 8.032286414365126E-218 poly(A)_RNA_binding GO:0008143 12133 11 47 1 94 4 2 false 0.39740305053187397 0.39740305053187397 1.4483869139240058E-14 regulation_of_lymphocyte_mediated_immunity GO:0002706 12133 63 47 1 158 1 2 false 0.39873417721520893 0.39873417721520893 1.105088874754345E-45 negative_regulation_of_peptidase_activity GO:0010466 12133 156 47 1 695 2 3 false 0.3987892107065618 0.3987892107065618 5.1885244604442586E-160 regulation_of_protein_binding GO:0043393 12133 95 47 1 6398 34 2 false 0.3994786622534804 0.3994786622534804 5.5524328548337306E-214 positive_regulation_of_endocytosis GO:0045807 12133 63 47 1 1023 8 4 false 0.39968283690740547 0.39968283690740547 3.3235317732048763E-102 regulation_of_mitochondrion_organization GO:0010821 12133 64 47 1 661 5 2 false 0.39999257858682696 0.39999257858682696 9.542606350434685E-91 positive_regulation_of_adenylate_cyclase_activity GO:0045762 12133 52 47 1 130 1 5 false 0.3999999999999939 0.3999999999999939 1.4124265749856537E-37 microtubule_associated_complex GO:0005875 12133 110 47 1 3267 15 3 false 0.4024229647637605 0.4024229647637605 2.821671595839563E-208 skeletal_muscle_cell_differentiation GO:0035914 12133 57 47 1 251 2 2 false 0.40331474103583304 0.40331474103583304 6.638453930425573E-58 poly-pyrimidine_tract_binding GO:0008187 12133 9 47 1 40 2 1 false 0.4038461538461555 0.4038461538461555 3.657124400158464E-9 negative_regulation_of_reproductive_process GO:2000242 12133 65 47 1 3420 27 3 false 0.4055364643823251 0.4055364643823251 2.9542142879788904E-139 antigen_processing_and_presentation GO:0019882 12133 185 47 2 1618 12 1 false 0.4065914870010909 0.4065914870010909 5.091289488805967E-249 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 47 1 2191 10 3 false 0.40892967038570294 0.40892967038570294 2.495063769189982E-191 post-Golgi_vesicle-mediated_transport GO:0006892 12133 70 47 1 170 1 1 false 0.4117647058823321 0.4117647058823321 1.5403758302393128E-49 viral_protein_processing GO:0019082 12133 10 47 1 256 13 2 false 0.41187151411926887 0.41187151411926887 3.5864633505920636E-18 Notch_signaling_pathway GO:0007219 12133 113 47 1 1975 9 1 false 0.4121976093505769 0.4121976093505769 2.33429872590278E-187 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 47 3 2776 10 3 false 0.4154317447001965 0.4154317447001965 0.0 cysteine-type_endopeptidase_activity GO:0004197 12133 219 47 1 527 1 2 false 0.4155597722959447 0.4155597722959447 1.229090165658057E-154 regulation_of_viral_reproduction GO:0050792 12133 101 47 1 6451 34 3 false 0.4160382289584799 0.4160382289584799 3.49743359338843E-225 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 47 2 541 3 2 false 0.41838125492735057 0.41838125492735057 1.01164377942614E-160 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 47 2 417 2 2 false 0.41868428334271485 0.41868428334271485 7.174398789465976E-117 potassium_ion_transmembrane_transport GO:0071805 12133 92 47 1 556 3 2 false 0.41941821311218713 0.41941821311218713 1.0312185181817459E-107 coagulation GO:0050817 12133 446 47 2 4095 13 1 false 0.42197745450908586 0.42197745450908586 0.0 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 47 2 2943 17 3 false 0.42200902142406554 0.42200902142406554 0.0 single-organism_cellular_process GO:0044763 12133 7541 47 37 9888 47 2 false 0.42226550956748055 0.42226550956748055 0.0 negative_regulation_of_blood_pressure GO:0045776 12133 28 47 1 117 2 1 false 0.4229295608605921 0.4229295608605921 1.267799191286988E-27 protein_alkylation GO:0008213 12133 98 47 1 2370 13 1 false 0.42328531746455733 0.42328531746455733 1.3558052911433636E-176 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 47 11 307 15 1 false 0.4256745783124616 0.4256745783124616 1.4733469150792184E-83 telencephalon_development GO:0021537 12133 141 47 1 3099 12 2 false 0.42868304367970544 0.42868304367970544 2.6342742970069075E-248 ion_transmembrane_transport GO:0034220 12133 556 47 3 970 4 2 false 0.42921600957535105 0.42921600957535105 1.3121997139332702E-286 regulation_of_adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002822 12133 70 47 1 163 1 2 false 0.42944785276073405 0.42944785276073405 6.913027082032024E-48 immune_effector_process GO:0002252 12133 445 47 4 1618 12 1 false 0.4295837835009456 0.4295837835009456 0.0 leukocyte_chemotaxis GO:0030595 12133 107 47 1 249 1 2 false 0.4297188755020236 0.4297188755020236 2.556499812614757E-73 organelle_outer_membrane GO:0031968 12133 110 47 1 9084 46 4 false 0.4298322541889728 0.4298322541889728 1.1973077012984011E-257 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 47 1 1054 6 3 false 0.4298668076475244 0.4298668076475244 5.573854633657796E-137 regulation_of_production_of_molecular_mediator_of_immune_response GO:0002700 12133 55 47 1 225 2 2 false 0.4299603174602877 0.4299603174602877 7.316653969426907E-54 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 47 1 557 19 2 false 0.4305373651259772 0.4305373651259772 3.0295698614548545E-31 positive_regulation_of_NF-kappaB_import_into_nucleus GO:0042346 12133 19 47 1 44 1 3 false 0.43181818181818316 0.43181818181818316 7.09808102783351E-13 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 47 9 3631 39 4 false 0.4323607494894836 0.4323607494894836 0.0 GTP_binding GO:0005525 12133 292 47 2 1635 8 3 false 0.4325342213188544 0.4325342213188544 0.0 membrane_organization GO:0061024 12133 787 47 6 3745 25 1 false 0.433248616063377 0.433248616063377 0.0 histone_methylation GO:0016571 12133 80 47 1 324 2 2 false 0.4334365325077039 0.4334365325077039 4.398247108446164E-78 cyclic_nucleotide_biosynthetic_process GO:0009190 12133 151 47 1 348 1 2 false 0.4339080459770588 0.4339080459770588 8.533554981861938E-103 RNA_modification GO:0009451 12133 64 47 1 4775 42 2 false 0.43402338016664344 0.43402338016664344 6.812362595459872E-147 positive_regulation_of_cell_cycle GO:0045787 12133 98 47 1 3492 20 3 false 0.4349756462671036 0.4349756462671036 2.23767062140918E-193 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 47 1 722 3 3 false 0.4351506961067408 0.4351506961067408 8.18717732691146E-144 regulation_of_NF-kappaB_import_into_nucleus GO:0042345 12133 34 47 1 197 3 3 false 0.4353600714006958 0.4353600714006958 5.91301474468331E-39 response_to_extracellular_stimulus GO:0009991 12133 260 47 1 1046 2 1 false 0.4355256296488402 0.4355256296488402 6.4524154237794786E-254 cAMP_biosynthetic_process GO:0006171 12133 124 47 1 284 1 3 false 0.4366197183098948 0.4366197183098948 6.647675853046176E-84 mRNA_stabilization GO:0048255 12133 22 47 2 33 2 2 false 0.43750000000000067 0.43750000000000067 5.166978132108427E-9 negative_regulation_of_molecular_function GO:0044092 12133 735 47 4 10257 47 2 false 0.4377410441199368 0.4377410441199368 0.0 development_of_primary_sexual_characteristics GO:0045137 12133 174 47 1 3105 10 3 false 0.43873533776470075 0.43873533776470075 2.1612319791507408E-290 immune_response-activating_signal_transduction GO:0002757 12133 299 47 5 352 5 2 false 0.4399822269587197 0.4399822269587197 2.8561568566531905E-64 double-strand_break_repair_via_homologous_recombination GO:0000724 12133 48 47 1 109 1 2 false 0.4403669724770689 0.4403669724770689 4.364037891784993E-32 clathrin-coated_vesicle_membrane GO:0030665 12133 87 47 1 197 1 2 false 0.44162436548220174 0.44162436548220174 3.3450134544276105E-58 response_to_salt_stress GO:0009651 12133 19 47 1 43 1 1 false 0.44186046511627686 0.44186046511627686 1.2492622608986976E-12 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 47 1 953 7 3 false 0.44215496917769853 0.44215496917769853 1.5807807987211998E-114 positive_regulation_of_response_to_external_stimulus GO:0032103 12133 126 47 1 1783 8 3 false 0.44428873625551474 0.44428873625551474 4.953245093659787E-197 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 47 1 574 2 3 false 0.4443451240795597 0.4443451240795597 1.1371703790830463E-140 positive_regulation_of_cyclic_nucleotide_metabolic_process GO:0030801 12133 80 47 1 180 1 3 false 0.44444444444442294 0.44444444444442294 3.3247573319336413E-53 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 47 5 1541 14 3 false 0.44494101901573835 0.44494101901573835 0.0 ATPase_activity GO:0016887 12133 307 47 2 1069 5 2 false 0.44540128214072716 0.44540128214072716 1.5605649392254874E-277 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 47 1 1198 9 4 false 0.4467314217374293 0.4467314217374293 2.335035261625238E-122 cellular_response_to_insulin_stimulus GO:0032869 12133 185 47 2 276 2 2 false 0.44848484848485837 0.44848484848485837 1.999097443178639E-75 positive_regulation_of_lymphocyte_activation GO:0051251 12133 188 47 1 419 1 3 false 0.44868735083532396 0.44868735083532396 1.71987955515036E-124 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 47 10 2595 20 2 false 0.44873406337138966 0.44873406337138966 0.0 mitosis GO:0007067 12133 326 47 3 953 7 2 false 0.4495632115797583 0.4495632115797583 4.8424843971573165E-265 regulation_of_skeletal_muscle_cell_differentiation GO:2001014 12133 27 47 1 105 2 3 false 0.4499999999999779 0.4499999999999779 1.1402717682449654E-25 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 47 7 4044 30 3 false 0.4521398404222498 0.4521398404222498 0.0 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 47 9 5558 41 3 false 0.45469314488196605 0.45469314488196605 0.0 positive_regulation_of_cAMP_metabolic_process GO:0030816 12133 71 47 1 155 1 4 false 0.4580645161290261 0.4580645161290261 5.885583975701031E-46 recombinational_repair GO:0000725 12133 48 47 1 416 5 2 false 0.4599920167755236 0.4599920167755236 4.005015877906007E-64 vasoconstriction GO:0042310 12133 46 47 1 100 1 1 false 0.4600000000000129 0.4600000000000129 1.3610812764552173E-29 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 47 2 7778 38 4 false 0.4625221429004994 0.4625221429004994 0.0 covalent_chromatin_modification GO:0016569 12133 312 47 2 458 2 1 false 0.46358919476766813 0.46358919476766813 7.826311589520491E-124 protein_binding,_bridging GO:0030674 12133 116 47 1 6397 34 2 false 0.4641081318987441 0.4641081318987441 3.1111419589573665E-251 immune_response-regulating_cell_surface_receptor_signaling_pathway_involved_in_phagocytosis GO:0002433 12133 72 47 1 500 4 2 false 0.4641862037326785 0.4641862037326785 6.2427882790248544E-89 binding,_bridging GO:0060090 12133 129 47 1 8962 43 1 false 0.4646961163415361 0.4646961163415361 1.7318913122999068E-292 mitotic_spindle_checkpoint GO:0071174 12133 38 47 1 140 2 2 false 0.4706063720451865 0.4706063720451865 3.73538767395573E-35 vesicle GO:0031982 12133 834 47 5 7980 43 1 false 0.47210588138646514 0.47210588138646514 0.0 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 47 1 1376 5 3 false 0.4725303142624345 0.4725303142624345 2.059495184181185E-218 gonad_development GO:0008406 12133 150 47 1 2876 12 4 false 0.47483748266060777 0.47483748266060777 4.529833702866928E-255 positive_regulation_of_protein_import_into_nucleus GO:0042307 12133 61 47 1 222 2 4 false 0.47495006318529487 0.47495006318529487 3.438523611225612E-56 response_to_insulin_stimulus GO:0032868 12133 216 47 2 313 2 1 false 0.4755468173998091 0.4755468173998091 1.4650294580642456E-83 Fc-gamma_receptor_signaling_pathway_involved_in_phagocytosis GO:0038096 12133 72 47 1 151 1 4 false 0.47682119205296153 0.47682119205296153 6.349846956956757E-45 regulation_of_muscle_tissue_development GO:1901861 12133 105 47 1 1351 8 2 false 0.4774352585963489 0.4774352585963489 1.3105194568745759E-159 positive_regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030804 12133 75 47 1 157 1 4 false 0.4777070063694132 0.4777070063694132 1.0054402594300752E-46 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 47 3 305 5 2 false 0.4783484247821383 0.4783484247821383 3.640759676212702E-91 blood_vessel_morphogenesis GO:0048514 12133 368 47 2 2812 12 3 false 0.4788336847268184 0.4788336847268184 0.0 monovalent_inorganic_cation_transmembrane_transporter_activity GO:0015077 12133 198 47 1 413 1 2 false 0.47941888619856315 0.47941888619856315 1.708187099767858E-123 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 47 9 5303 36 3 false 0.4806505068287264 0.4806505068287264 0.0 T_cell_receptor_signaling_pathway GO:0050852 12133 88 47 3 112 3 1 false 0.4814671814671709 0.4814671814671709 5.828412725788921E-25 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 47 2 129 3 1 false 0.4824236632484805 0.4824236632484805 2.169508265339551E-38 protein_domain_specific_binding GO:0019904 12133 486 47 3 6397 34 1 false 0.4834680297839091 0.4834680297839091 0.0 purine_nucleoside_catabolic_process GO:0006152 12133 939 47 5 1085 5 3 false 0.4847915589422494 0.4847915589422494 2.1746006434797338E-185 cytokine-mediated_signaling_pathway GO:0019221 12133 318 47 2 2013 10 2 false 0.48507248746261095 0.48507248746261095 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 47 2 442 3 3 false 0.48639595698429194 0.48639595698429194 2.4953498472018727E-132 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 47 2 140 2 1 false 0.4884892086330724 0.4884892086330724 9.838676628741767E-37 negative_regulation_of_cell_communication GO:0010648 12133 599 47 3 4860 21 3 false 0.4886135991644433 0.4886135991644433 0.0 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 47 1 1881 9 2 false 0.48919597931826553 0.48919597931826553 3.367676499542027E-210 ribonucleotide_catabolic_process GO:0009261 12133 946 47 5 1294 6 3 false 0.48931961266204416 0.48931961266204416 0.0 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 47 11 7638 45 4 false 0.4906194112705773 0.4906194112705773 0.0 regulation_of_cAMP_metabolic_process GO:0030814 12133 133 47 1 465 2 3 false 0.49067482387843386 0.49067482387843386 3.255746313776628E-120 BMP_signaling_pathway GO:0030509 12133 83 47 1 1276 10 2 false 0.4908724318499221 0.4908724318499221 9.874891335860256E-133 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 47 3 129 3 1 false 0.4912676249771082 0.4912676249771082 2.104544859412626E-28 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 47 25 6638 44 2 false 0.49164148089321996 0.49164148089321996 0.0 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 47 1 130 1 2 false 0.4923076923076922 0.4923076923076922 1.0680656075518395E-38 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 47 2 129 3 1 false 0.49414026735030403 0.49414026735030403 2.1037655906323275E-38 nuclear_pore GO:0005643 12133 69 47 1 2781 27 3 false 0.4941856305759811 0.4941856305759811 8.971129873692015E-140 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 47 3 3702 15 3 false 0.4942230956427439 0.4942230956427439 0.0 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 47 1 676 8 2 false 0.49469495571096733 0.49469495571096733 2.737610529852072E-82 renal_system_development GO:0072001 12133 196 47 1 2686 9 2 false 0.49489593897745043 0.49489593897745043 5.871867151923005E-304 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 47 3 312 3 1 false 0.4949045742142752 0.4949045742142752 8.216510305576978E-69 negative_regulation_of_NF-kappaB_transcription_factor_activity GO:0032088 12133 51 47 1 103 1 1 false 0.4951456310679525 0.4951456310679525 1.2633713261943138E-30 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 47 3 2935 22 1 false 0.49582751309006773 0.49582751309006773 0.0 cytoskeleton_organization GO:0007010 12133 719 47 4 2031 10 1 false 0.49718145399745056 0.49718145399745056 0.0 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 47 1 741 6 2 false 0.49739143861842805 0.49739143861842805 1.553661553762129E-109 cation_channel_activity GO:0005261 12133 216 47 1 433 1 2 false 0.4988452655890016 0.4988452655890016 1.1777872542675005E-129 nucleotide_catabolic_process GO:0009166 12133 969 47 5 1318 6 2 false 0.4989127590945578 0.4989127590945578 0.0 kidney_development GO:0001822 12133 161 47 1 2877 12 3 false 0.49963533679647565 0.49963533679647565 9.385342690705625E-269 histone_H3-K4_methylation GO:0051568 12133 33 47 1 66 1 1 false 0.5000000000000062 0.5000000000000062 1.3851512057218646E-19 ATP_catabolic_process GO:0006200 12133 318 47 2 1012 5 4 false 0.5011075246236468 0.5011075246236468 1.0026310858617265E-272 cell_chemotaxis GO:0060326 12133 132 47 1 2155 11 3 false 0.5019086224710185 0.5019086224710185 6.49351277121459E-215 nucleolus GO:0005730 12133 1357 47 13 4208 39 3 false 0.502438332865828 0.502438332865828 0.0 peptidyl-lysine_modification GO:0018205 12133 185 47 1 623 2 1 false 0.5060566804127797 0.5060566804127797 7.634244791194444E-164 cellular_response_to_interferon-gamma GO:0071346 12133 83 47 1 392 3 2 false 0.5112124448441729 0.5112124448441729 2.629901965674187E-87 cellular_chemical_homeostasis GO:0055082 12133 525 47 2 734 2 2 false 0.5113173810732686 0.5113173810732686 1.1478565010718528E-189 regulation_of_mitosis GO:0007088 12133 100 47 1 611 4 4 false 0.5117068254339328 0.5117068254339328 1.2375244614825155E-117 regulation_of_metal_ion_transport GO:0010959 12133 159 47 1 527 2 2 false 0.5127885080195242 0.5127885080195242 1.9143009234930405E-139 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 47 13 106 13 2 false 0.5128363307220508 0.5128363307220508 9.867686559172291E-9 locomotion GO:0040011 12133 1045 47 5 10446 47 1 false 0.5128365967370732 0.5128365967370732 0.0 production_of_molecular_mediator_of_immune_response GO:0002440 12133 94 47 1 1618 12 1 false 0.5136159204662798 0.5136159204662798 3.880703619863946E-155 histone_modification GO:0016570 12133 306 47 2 2375 13 2 false 0.5140574671481924 0.5140574671481924 0.0 lyase_activity GO:0016829 12133 230 47 1 4901 15 1 false 0.5142437530093671 0.5142437530093671 0.0 activation_of_innate_immune_response GO:0002218 12133 155 47 3 362 6 2 false 0.5143524555811783 0.5143524555811783 1.0665156090103768E-106 positive_regulation_of_cAMP_biosynthetic_process GO:0030819 12133 69 47 1 134 1 5 false 0.5149253731343213 0.5149253731343213 7.0817799397690005E-40 negative_regulation_of_signaling GO:0023057 12133 597 47 3 4884 22 3 false 0.5151108047697657 0.5151108047697657 0.0 regulation_of_transcription_factor_import_into_nucleus GO:0042990 12133 63 47 1 122 1 2 false 0.5163934426229579 0.5163934426229579 2.784334919854664E-36 growth_factor_binding GO:0019838 12133 135 47 1 6397 34 1 false 0.5166917298594429 0.5166917298594429 1.7435678435075742E-283 male_gonad_development GO:0008584 12133 84 47 1 162 1 2 false 0.5185185185184836 0.5185185185184836 3.0520910486495067E-48 negative_regulation_of_mRNA_splicing,_via_spliceosome GO:0048025 12133 11 47 1 207 13 4 false 0.5190150983628539 0.5190150983628539 1.749347829328537E-18 SH3_domain_binding GO:0017124 12133 105 47 1 486 3 1 false 0.5190228853144792 0.5190228853144792 1.6190468269923415E-109 regulation_of_leukocyte_mediated_immunity GO:0002703 12133 84 47 1 274 2 2 false 0.5199326221222871 0.5199326221222871 8.733942624679482E-73 regulation_of_cellular_component_movement GO:0051270 12133 412 47 2 6475 27 3 false 0.5200371958121663 0.5200371958121663 0.0 GTPase_binding GO:0051020 12133 137 47 1 1005 5 1 false 0.5201736896141022 0.5201736896141022 4.2154504665352884E-173 regulation_of_endocytosis GO:0030100 12133 113 47 1 1437 9 3 false 0.5225273119951465 0.5225273119951465 3.3139638850760945E-171 microtubule_cytoskeleton GO:0015630 12133 734 47 3 1430 5 1 false 0.5249357489978962 0.5249357489978962 0.0 taxis GO:0042330 12133 488 47 2 1496 5 2 false 0.5251404535254655 0.5251404535254655 0.0 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 47 3 178 4 1 false 0.5256522567131074 0.5256522567131074 1.7238002808689451E-50 mRNA_export_from_nucleus GO:0006406 12133 60 47 2 116 3 2 false 0.5260790657303032 0.5260790657303032 1.7435958103584361E-34 regulation_of_immune_effector_process GO:0002697 12133 188 47 2 891 8 2 false 0.5292815320393316 0.5292815320393316 1.2449327492079068E-198 reproductive_system_development GO:0061458 12133 216 47 1 2686 9 1 false 0.5303131973181445 0.5303131973181445 0.0 peptidase_activity GO:0008233 12133 614 47 2 2556 7 1 false 0.5305928282920387 0.5305928282920387 0.0 regulation_of_transmembrane_transport GO:0034762 12133 183 47 1 6614 27 3 false 0.5319104043498624 0.5319104043498624 0.0 ribonucleoside_catabolic_process GO:0042454 12133 946 47 5 1073 5 2 false 0.5320005406987649 0.5320005406987649 9.25790942536024E-169 protein_K63-linked_ubiquitination GO:0070534 12133 28 47 1 163 4 1 false 0.5331088290210505 0.5331088290210505 4.092462206953933E-32 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 47 9 5151 41 4 false 0.5341423610716336 0.5341423610716336 0.0 tight_junction_assembly GO:0070830 12133 31 47 1 58 1 2 false 0.5344827586206974 0.5344827586206974 3.809192954277456E-17 phosphorus-oxygen_lyase_activity GO:0016849 12133 123 47 1 230 1 1 false 0.5347826086956033 0.5347826086956033 1.920154677041111E-68 cAMP_metabolic_process GO:0046058 12133 143 47 1 1194 6 2 false 0.5356498942520943 0.5356498942520943 2.6525041284959264E-189 carboxylic_acid_binding GO:0031406 12133 186 47 1 2280 9 1 false 0.5357351672105026 0.5357351672105026 4.771798836819993E-279 ubiquitin-protein_ligase_activity GO:0004842 12133 321 47 5 558 8 2 false 0.5362869741075862 0.5362869741075862 1.7708856343357755E-164 transcription_factor_binding GO:0008134 12133 715 47 4 6397 34 1 false 0.5366952192277237 0.5366952192277237 0.0 cellular_component_organization GO:0016043 12133 3745 47 25 3839 25 1 false 0.537015980525344 0.537015980525344 4.153510440731863E-191 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 47 5 504 6 1 false 0.538080519695495 0.538080519695495 6.011520399617331E-122 transcription_factor_import_into_nucleus GO:0042991 12133 64 47 1 200 2 1 false 0.5386934673366423 0.5386934673366423 5.887023324562289E-54 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 47 5 1054 5 2 false 0.5399275587687933 0.5399275587687933 2.3625686453162704E-163 B_cell_mediated_immunity GO:0019724 12133 92 47 1 170 1 2 false 0.541176470588214 0.541176470588214 1.940857539818752E-50 development_of_primary_male_sexual_characteristics GO:0046546 12133 97 47 1 179 1 2 false 0.5418994413407667 0.5418994413407667 4.0970386268467766E-53 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 47 3 1813 9 1 false 0.5420280188224533 0.5420280188224533 0.0 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 47 1 260 2 3 false 0.5426195426195495 0.5426195426195495 1.712440969539876E-70 protein_dephosphorylation GO:0006470 12133 146 47 1 2505 13 2 false 0.5427824270636799 0.5427824270636799 5.1980515318736674E-241 purine_nucleotide_metabolic_process GO:0006163 12133 1208 47 6 1337 6 2 false 0.5433645969325496 0.5433645969325496 1.5771526523631757E-183 stress-activated_MAPK_cascade GO:0051403 12133 207 47 2 504 4 2 false 0.543623715025094 0.543623715025094 1.7060805667457382E-147 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 47 7 2877 21 6 false 0.5439695788457658 0.5439695788457658 0.0 regulation_of_blood_vessel_size GO:0050880 12133 100 47 1 308 2 3 false 0.5446507889503569 0.5446507889503569 9.949875270663928E-84 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 47 5 1060 5 3 false 0.5448401233302466 0.5448401233302466 8.715047292960447E-163 regulation_of_cyclic_nucleotide_metabolic_process GO:0030799 12133 156 47 1 478 2 2 false 0.546669824478405 0.546669824478405 1.998151187516486E-130 small_conjugating_protein_ligase_binding GO:0044389 12133 147 47 1 1005 5 1 false 0.5472448977031441 0.5472448977031441 6.302468729220369E-181 protein_import GO:0017038 12133 225 47 2 2509 20 2 false 0.5472579875708076 0.5472579875708076 0.0 ribonucleoprotein_granule GO:0035770 12133 75 47 1 3365 35 2 false 0.5475024275789182 0.5475024275789182 1.704323678285534E-155 regulation_of_endopeptidase_activity GO:0052548 12133 264 47 1 480 1 2 false 0.550000000000017 0.550000000000017 9.691263405564588E-143 cellular_response_to_organic_nitrogen GO:0071417 12133 323 47 2 1478 8 4 false 0.5502715242867118 0.5502715242867118 0.0 ATPase_activity,_coupled GO:0042623 12133 228 47 2 307 2 1 false 0.5509356837196387 0.5509356837196387 1.7947531856464704E-75 response_to_interferon-gamma GO:0034341 12133 97 47 1 900 7 2 false 0.5511710475393112 0.5511710475393112 5.665951698458868E-133 receptor_metabolic_process GO:0043112 12133 101 47 1 5613 44 1 false 0.5515901925501836 0.5515901925501836 4.997034842501505E-219 structure-specific_DNA_binding GO:0043566 12133 179 47 1 2091 9 1 false 0.5538275973364155 0.5538275973364155 1.2928223396172998E-264 urogenital_system_development GO:0001655 12133 231 47 1 2686 9 1 false 0.5554091891467671 0.5554091891467671 0.0 G1_DNA_damage_checkpoint GO:0044783 12133 70 47 1 126 1 1 false 0.5555555555555676 0.5555555555555676 3.590272155218709E-37 intracellular_estrogen_receptor_signaling_pathway GO:0030520 12133 34 47 1 102 2 1 false 0.5577557755775552 0.5577557755775552 7.615480469304384E-28 positive_regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900740 12133 24 47 1 43 1 3 false 0.558139534883719 0.558139534883719 1.2492622608986976E-12 DNA_catabolic_process GO:0006308 12133 66 47 1 2145 26 3 false 0.5584284524007118 0.5584284524007118 1.9973602853494904E-127 skeletal_muscle_organ_development GO:0060538 12133 172 47 1 308 1 1 false 0.5584415584415203 0.5584415584415203 3.4535917571053045E-91 cellular_macromolecular_complex_assembly GO:0034622 12133 517 47 3 973 5 1 false 0.5587409227216424 0.5587409227216424 3.312522477266262E-291 passive_transmembrane_transporter_activity GO:0022803 12133 304 47 1 544 1 1 false 0.5588235294118147 0.5588235294118147 2.1953421087848878E-161 regulation_of_binding GO:0051098 12133 172 47 1 9142 43 2 false 0.558960405203256 0.558960405203256 0.0 protein_localization GO:0008104 12133 1434 47 17 1642 19 1 false 0.5603907868653142 0.5603907868653142 3.426309620265761E-270 chromatin GO:0000785 12133 287 47 1 512 1 1 false 0.5605468749999285 0.5605468749999285 9.050120143931621E-152 regulation_of_peptidase_activity GO:0052547 12133 276 47 1 1151 3 2 false 0.5610242427403002 0.5610242427403002 1.6233323078676786E-274 transport_vesicle_membrane GO:0030658 12133 63 47 1 340 4 2 false 0.5612199317237726 0.5612199317237726 3.001775130471713E-70 cyclic_purine_nucleotide_metabolic_process GO:0052652 12133 151 47 1 269 1 2 false 0.5613382899628113 0.5613382899628113 1.6379011785432358E-79 transport_vesicle GO:0030133 12133 108 47 1 712 5 1 false 0.5617831946787781 0.5617831946787781 5.898553548536589E-131 negative_regulation_of_organelle_organization GO:0010639 12133 168 47 1 2125 10 3 false 0.5619467140650254 0.5619467140650254 2.2467097914760192E-254 regulation_of_body_fluid_levels GO:0050878 12133 527 47 2 4595 16 2 false 0.5628142736302454 0.5628142736302454 0.0 endosome_membrane GO:0010008 12133 248 47 1 1627 5 2 false 0.5630793693628897 0.5630793693628897 8.244139595488818E-301 regulation_of_actin_filament-based_process GO:0032970 12133 192 47 1 6365 27 2 false 0.5633882129531971 0.5633882129531971 0.0 metal_ion_transport GO:0030001 12133 455 47 2 606 2 1 false 0.5634290701797242 0.5634290701797242 4.665536224038032E-147 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 47 14 181 14 1 false 0.5635503843363997 0.5635503843363997 8.905994863592909E-13 negative_regulation_of_hydrolase_activity GO:0051346 12133 241 47 1 2738 9 3 false 0.5641735726590011 0.5641735726590011 0.0 cellular_developmental_process GO:0048869 12133 2267 47 11 7817 38 2 false 0.5641921777811862 0.5641921777811862 0.0 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 47 2 129 3 1 false 0.5642996932796249 0.5642996932796249 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 47 2 129 3 1 false 0.5642996932796249 0.5642996932796249 3.3394798770258706E-38 regulation_of_lymphocyte_activation GO:0051249 12133 245 47 1 434 1 2 false 0.5645161290321338 0.5645161290321338 2.1869753110099554E-128 regulation_of_translation GO:0006417 12133 210 47 2 3605 32 4 false 0.564525491187696 0.564525491187696 0.0 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 47 1 308 1 2 false 0.5649350649350205 0.5649350649350205 5.66231040699253E-91 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 47 1 3406 19 3 false 0.5659836954050764 0.5659836954050764 5.390613252169377E-261 cellular_component_movement GO:0006928 12133 1012 47 5 7541 37 1 false 0.5661809693318851 0.5661809693318851 0.0 nuclear_export GO:0051168 12133 116 47 3 688 17 2 false 0.5672399533917314 0.5672399533917314 6.892155989004194E-135 substrate-specific_channel_activity GO:0022838 12133 291 47 1 512 1 2 false 0.5683593749999285 0.5683593749999285 2.547694139879492E-151 cell_junction_assembly GO:0034329 12133 159 47 1 1406 7 2 false 0.5691380672854452 0.5691380672854452 9.423437086545545E-215 cellular_response_to_nitrogen_compound GO:1901699 12133 347 47 2 1721 9 2 false 0.5692266459117273 0.5692266459117273 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 47 4 701 6 2 false 0.5692446785574488 0.5692446785574488 1.5434745144062482E-202 nuclear_import GO:0051170 12133 203 47 2 2389 22 3 false 0.5697261136117424 0.5697261136117424 7.452348105569065E-301 protein_C-terminus_binding GO:0008022 12133 157 47 1 6397 34 1 false 0.5713345728297852 0.5713345728297852 2.34014E-319 regulation_of_vesicle-mediated_transport GO:0060627 12133 196 47 1 6585 28 3 false 0.5716565934586415 0.5716565934586415 0.0 organelle_organization GO:0006996 12133 2031 47 10 7663 38 2 false 0.5722871536292624 0.5722871536292624 0.0 ribonucleotide_metabolic_process GO:0009259 12133 1202 47 6 1318 6 2 false 0.5747195280802102 0.5747195280802102 7.680938106405399E-170 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 47 2 129 3 1 false 0.5759161554660286 0.5759161554660286 4.0186961232005657E-38 regulation_of_actin_cytoskeleton_organization GO:0032956 12133 166 47 1 476 2 3 false 0.576337903582687 0.576337903582687 5.437988564533384E-133 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 47 22 6094 42 2 false 0.5775402193165615 0.5775402193165615 0.0 regulation_of_transmission_of_nerve_impulse GO:0051969 12133 160 47 1 2127 11 4 false 0.5778284550519166 0.5778284550519166 7.858109974637731E-246 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 47 5 1319 6 1 false 0.5788190907221463 0.5788190907221463 6.536050345296563E-309 reproductive_structure_development GO:0048608 12133 216 47 1 3110 12 3 false 0.5791105959393256 0.5791105959393256 0.0 cyclic_nucleotide_metabolic_process GO:0009187 12133 177 47 1 1317 6 1 false 0.5801016658784943 0.5801016658784943 5.758082552903037E-225 negative_regulation_of_cell_cycle GO:0045786 12133 298 47 2 3131 20 3 false 0.5808598160306326 0.5808598160306326 0.0 contractile_fiber_part GO:0044449 12133 144 47 1 7199 43 3 false 0.5816382462008838 0.5816382462008838 8.364096489052254E-306 chemotaxis GO:0006935 12133 488 47 2 2369 9 2 false 0.5820925847913465 0.5820925847913465 0.0 mRNA_3'-end_processing GO:0031124 12133 86 47 3 386 13 2 false 0.5826185879324897 0.5826185879324897 2.4694341980396157E-88 skeletal_muscle_tissue_development GO:0007519 12133 168 47 1 288 1 2 false 0.5833333333332881 0.5833333333332881 2.348024843062379E-84 poly-purine_tract_binding GO:0070717 12133 14 47 1 40 2 1 false 0.5833333333333363 0.5833333333333363 4.309057712047628E-11 negative_regulation_of_immune_system_process GO:0002683 12133 144 47 1 3524 21 3 false 0.5846733146793528 0.5846733146793528 1.8096661454151343E-260 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 47 2 929 6 2 false 0.5857535836075194 0.5857535836075194 1.7613668775256747E-246 protein_acylation GO:0043543 12133 155 47 1 2370 13 1 false 0.5858800619584206 0.5858800619584206 6.767829300235778E-248 regulation_of_reproductive_process GO:2000241 12133 171 47 1 6891 35 2 false 0.5859160876412088 0.5859160876412088 0.0 transition_metal_ion_binding GO:0046914 12133 1457 47 4 2699 7 1 false 0.5866716046913927 0.5866716046913927 0.0 proteasomal_protein_catabolic_process GO:0010498 12133 231 47 3 498 6 2 false 0.5869207604722881 0.5869207604722881 1.2543475178088858E-148 muscle_system_process GO:0003012 12133 252 47 1 1272 4 1 false 0.5870047261698814 0.5870047261698814 3.711105192357829E-274 regulation_of_phosphorylation GO:0042325 12133 845 47 3 1820 6 2 false 0.5873097095916107 0.5873097095916107 0.0 JNK_cascade GO:0007254 12133 159 47 2 207 2 1 false 0.5891374700998838 0.5891374700998838 3.1556682987155503E-48 clathrin_coat GO:0030118 12133 39 47 1 66 1 1 false 0.5909090909090968 0.5909090909090968 4.080314872103393E-19 steroid_biosynthetic_process GO:0006694 12133 98 47 1 3573 32 3 false 0.590940061803741 0.590940061803741 2.291833143174281E-194 amino_acid_binding GO:0016597 12133 110 47 1 186 1 1 false 0.5913978494623976 0.5913978494623976 3.905422178213833E-54 contractile_fiber GO:0043292 12133 159 47 1 6670 37 2 false 0.591449280336098 0.591449280336098 0.0 MAPK_cascade GO:0000165 12133 502 47 4 806 6 1 false 0.5917184991112021 0.5917184991112021 3.7900857366173457E-231 regulation_of_programmed_cell_death GO:0043067 12133 1031 47 4 1410 5 2 false 0.5931607591278806 0.5931607591278806 0.0 cell_cycle_phase GO:0022403 12133 253 47 2 953 7 1 false 0.5935418049386614 0.5935418049386614 1.0384727319913012E-238 erythrocyte_differentiation GO:0030218 12133 88 47 1 243 2 2 false 0.5940890385333677 0.5940890385333677 1.540826297870933E-68 sex_differentiation GO:0007548 12133 202 47 1 340 1 1 false 0.5941176470587681 0.5941176470587681 4.342696063294865E-99 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 47 2 136 2 2 false 0.5947712418300675 0.5947712418300675 2.4301849830786213E-31 muscle_tissue_development GO:0060537 12133 295 47 1 1132 3 1 false 0.5961400979081191 0.5961400979081191 3.412889797328503E-281 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 47 3 1350 7 4 false 0.5964763344958695 0.5964763344958695 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 47 4 1779 5 1 false 0.5969406854877479 0.5969406854877479 0.0 cell_junction_organization GO:0034330 12133 181 47 1 7663 38 2 false 0.5976997073334887 0.5976997073334887 0.0 DNA_metabolic_process GO:0006259 12133 791 47 6 5627 44 2 false 0.5983613111460249 0.5983613111460249 0.0 iron_ion_transport GO:0006826 12133 36 47 1 60 1 1 false 0.6000000000000054 0.6000000000000054 2.7737414075406367E-17 cell_cortex GO:0005938 12133 175 47 1 6402 33 2 false 0.6002620453563831 0.6002620453563831 0.0 positive_regulation_of_nucleocytoplasmic_transport GO:0046824 12133 75 47 1 367 4 3 false 0.6009472726764089 0.6009472726764089 3.7707577442500014E-80 somatic_cell_DNA_recombination GO:0016444 12133 50 47 1 190 3 1 false 0.6022147567500091 0.6022147567500091 4.229558413024195E-47 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 47 1 3297 19 3 false 0.602892785791233 0.602892785791233 4.623981712175632E-272 ion_channel_activity GO:0005216 12133 286 47 1 473 1 2 false 0.6046511627906472 0.6046511627906472 3.7303800171637374E-137 regulation_of_ion_transmembrane_transport GO:0034765 12133 176 47 1 662 3 3 false 0.6049791810449912 0.6049791810449912 9.171243521861199E-166 response_to_chemical_stimulus GO:0042221 12133 2369 47 9 5200 20 1 false 0.6055335748775313 0.6055335748775313 0.0 cell_activation_involved_in_immune_response GO:0002263 12133 119 47 1 1341 10 3 false 0.6064517264333338 0.6064517264333338 8.435334491810511E-174 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 47 1 766 1 2 false 0.6070496083553625 0.6070496083553625 4.217322594612318E-222 regulation_of_apoptotic_process GO:0042981 12133 1019 47 4 1381 5 2 false 0.6072043666016679 0.6072043666016679 0.0 estrogen_receptor_binding GO:0030331 12133 23 47 1 62 2 1 false 0.6081438392385131 0.6081438392385131 1.6756493074771417E-17 double-stranded_DNA_binding GO:0003690 12133 109 47 1 179 1 1 false 0.6089385474860085 0.6089385474860085 1.5496409193142626E-51 purine_nucleotide_catabolic_process GO:0006195 12133 956 47 5 1223 6 3 false 0.6103320141827606 0.6103320141827606 6.80299167777575E-278 rRNA_binding GO:0019843 12133 29 47 1 763 24 1 false 0.6111549438662003 0.6111549438662003 3.8668021308986908E-53 protein_maturation GO:0051604 12133 123 47 1 5551 42 2 false 0.6111809764332387 0.6111809764332387 1.3126924681575497E-255 chromatin_organization GO:0006325 12133 539 47 2 689 2 1 false 0.6117350727373879 0.6117350727373879 4.375882251809235E-156 system_process GO:0003008 12133 1272 47 4 4095 13 1 false 0.6122356437296638 0.6122356437296638 0.0 ATP_metabolic_process GO:0046034 12133 381 47 2 1209 6 3 false 0.6124243990735292 0.6124243990735292 0.0 mRNA_processing GO:0006397 12133 374 47 13 763 27 2 false 0.6125697901447558 0.6125697901447558 8.270510506831645E-229 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 47 1 170 2 3 false 0.6126000696135618 0.6126000696135618 2.004129732487635E-48 spindle_organization GO:0007051 12133 78 47 1 1776 21 3 false 0.612732069484281 0.612732069484281 2.2015050227101385E-138 transmission_of_nerve_impulse GO:0019226 12133 586 47 2 4105 14 3 false 0.6148557406239681 0.6148557406239681 0.0 somatic_diversification_of_immunoglobulins GO:0016445 12133 45 47 1 73 1 2 false 0.6164383561643858 0.6164383561643858 8.158943815315171E-21 forebrain_development GO:0030900 12133 242 47 1 3152 12 3 false 0.6172429556306499 0.6172429556306499 0.0 ion_homeostasis GO:0050801 12133 532 47 2 677 2 1 false 0.6172637724733726 0.6172637724733726 5.041033537922393E-152 programmed_cell_death GO:0012501 12133 1385 47 5 1525 5 1 false 0.6174633498792961 0.6174633498792961 2.142172117700311E-202 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 47 1 269 2 2 false 0.6200688009764193 0.6200688009764193 3.613555574654199E-77 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 47 1 768 1 1 false 0.6210937499998362 0.6210937499998362 1.6461815804374103E-220 regulation_of_inflammatory_response GO:0050727 12133 151 47 1 702 4 3 false 0.6213509727799741 0.6213509727799741 5.1007818439049374E-158 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 47 6 3771 30 4 false 0.621659071174177 0.621659071174177 0.0 vascular_process_in_circulatory_system GO:0003018 12133 118 47 1 307 2 1 false 0.6217666219580926 0.6217666219580926 3.250495259622763E-88 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 47 2 129 3 1 false 0.6219528245742534 0.6219528245742534 1.1512773005265922E-37 RNA_3'-end_processing GO:0031123 12133 98 47 3 601 19 1 false 0.6232562170296746 0.6232562170296746 1.9130441150898719E-115 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 47 5 1202 6 3 false 0.6234256527068106 0.6234256527068106 1.616697592155103E-269 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 47 12 6129 44 3 false 0.6237152046613623 0.6237152046613623 0.0 multicellular_organismal_signaling GO:0035637 12133 604 47 2 5594 19 2 false 0.6240285407904387 0.6240285407904387 0.0 in_utero_embryonic_development GO:0001701 12133 295 47 1 471 1 1 false 0.6263269639064891 0.6263269639064891 1.719393530200133E-134 histone_acetylation GO:0016573 12133 121 47 1 309 2 2 false 0.6306056403142446 0.6306056403142446 3.1224257129978892E-89 kinase_binding GO:0019900 12133 384 47 2 1005 5 1 false 0.6318876615800691 0.6318876615800691 2.0091697589355545E-289 U5_snRNP GO:0005682 12133 80 47 3 93 3 1 false 0.6331396513724712 0.6331396513724712 3.852654648545616E-16 actin_filament-based_process GO:0030029 12133 431 47 2 7541 37 1 false 0.6331988305905211 0.6331988305905211 0.0 polysome GO:0005844 12133 22 47 1 569 25 1 false 0.6349198024777066 0.6349198024777066 4.138788255326549E-40 positive_regulation_of_cytokine_production GO:0001819 12133 175 47 1 614 3 3 false 0.6352126245125008 0.6352126245125008 1.2195240299259301E-158 membrane-bounded_vesicle GO:0031988 12133 762 47 5 834 5 1 false 0.6359906155818421 0.6359906155818421 6.820230733401612E-106 cell_activation GO:0001775 12133 656 47 3 7541 37 1 false 0.6360918103935744 0.6360918103935744 0.0 mRNA_3'-UTR_binding GO:0003730 12133 20 47 1 91 4 1 false 0.6364553049946136 0.6364553049946136 1.5304206568397613E-20 enzyme_binding GO:0019899 12133 1005 47 5 6397 34 1 false 0.6366108465966247 0.6366108465966247 0.0 interaction_with_host GO:0051701 12133 387 47 6 417 6 2 false 0.6371288476432639 0.6371288476432639 1.9217516081652173E-46 apical_junction_assembly GO:0043297 12133 37 47 1 58 1 1 false 0.6379310344827669 0.6379310344827669 2.991639077401756E-16 cellular_protein_complex_disassembly GO:0043624 12133 149 47 13 154 13 1 false 0.6394957406263921 0.6394957406263921 1.4793035521715585E-9 egress_of_virus_within_host_cell GO:0046788 12133 11 47 1 28 2 2 false 0.640211640211643 0.640211640211643 4.656755228837597E-8 peptidyl-lysine_acetylation GO:0018394 12133 127 47 1 198 1 2 false 0.6414141414141271 0.6414141414141271 1.293028032371008E-55 GTPase_activity GO:0003924 12133 612 47 3 1061 5 2 false 0.6420364666593191 0.6420364666593191 4.702100395E-313 cell_division GO:0051301 12133 438 47 2 7541 37 1 false 0.6421339105343622 0.6421339105343622 0.0 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 47 6 2771 24 5 false 0.6426636876833285 0.6426636876833285 0.0 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 47 2 217 4 1 false 0.6427939873263465 0.6427939873263465 1.2933579260360868E-64 regulatory_region_DNA_binding GO:0000975 12133 1169 47 5 2091 9 2 false 0.6429427157282782 0.6429427157282782 0.0 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 47 2 1399 5 3 false 0.6438593527660524 0.6438593527660524 0.0 cellular_response_to_hormone_stimulus GO:0032870 12133 384 47 2 1510 8 3 false 0.6441867931448424 0.6441867931448424 0.0 regulation_of_adaptive_immune_response GO:0002819 12133 78 47 1 570 7 2 false 0.6451260775267613 0.6451260775267613 3.127506712292269E-98 regulation_of_multi-organism_process GO:0043900 12133 193 47 1 6817 36 2 false 0.6453503611734501 0.6453503611734501 0.0 negative_regulation_of_apoptotic_process GO:0043066 12133 537 47 2 1377 5 3 false 0.6458686244922099 0.6458686244922099 0.0 protein_K48-linked_ubiquitination GO:0070936 12133 37 47 1 163 4 1 false 0.6468502711834003 0.6468502711834003 1.6289154422281443E-37 wound_healing GO:0042060 12133 543 47 2 905 3 1 false 0.6481595272399266 0.6481595272399266 1.120707554751266E-263 blood_coagulation GO:0007596 12133 443 47 2 550 2 3 false 0.6484716012585028 0.6484716012585028 4.662213706291943E-117 protein_heterodimerization_activity GO:0046982 12133 317 47 1 779 2 1 false 0.6485805082650417 0.6485805082650417 8.49214053182804E-228 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 47 2 1759 11 2 false 0.6496417289190721 0.6496417289190721 0.0 regulation_of_homeostatic_process GO:0032844 12133 239 47 1 6742 29 2 false 0.6496829950854855 0.6496829950854855 0.0 regulation_of_Rho_GTPase_activity GO:0032319 12133 95 47 1 233 2 2 false 0.650251590942715 0.650251590942715 7.3761210037366725E-68 protein_ubiquitination GO:0016567 12133 548 47 8 578 8 1 false 0.6511179672550621 0.6511179672550621 7.913703273197485E-51 phosphorylation GO:0016310 12133 1421 47 5 2776 10 1 false 0.6521948395416199 0.6521948395416199 0.0 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 47 1 2776 10 3 false 0.6525083708176205 0.6525083708176205 0.0 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 47 3 639 6 3 false 0.6525625443700662 0.6525625443700662 1.399157780258238E-191 kinase_activity GO:0016301 12133 1174 47 4 1546 5 2 false 0.6526159370466273 0.6526159370466273 0.0 ATP_binding GO:0005524 12133 1212 47 6 1638 8 3 false 0.6534303688247163 0.6534303688247163 0.0 regulation_of_nuclear_division GO:0051783 12133 100 47 1 712 7 2 false 0.6550206466868154 0.6550206466868154 7.811073934054147E-125 cell_cycle_phase_transition GO:0044770 12133 415 47 3 953 7 1 false 0.6553714274168021 0.6553714274168021 1.4433288987581492E-282 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 47 2 129 3 1 false 0.6558694607215028 0.6558694607215028 3.5310664374642874E-37 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 47 7 4429 36 3 false 0.6559457167581434 0.6559457167581434 0.0 regulation_of_lipid_metabolic_process GO:0019216 12133 182 47 1 4352 25 2 false 0.6573367368233073 0.6573367368233073 0.0 regulation_of_cell_development GO:0060284 12133 446 47 2 1519 7 2 false 0.6574410564654289 0.6574410564654289 0.0 response_to_nitrogen_compound GO:1901698 12133 552 47 2 2369 9 1 false 0.6574711033749003 0.6574711033749003 0.0 zinc_ion_binding GO:0008270 12133 1314 47 4 1457 4 1 false 0.6612235173177182 0.6612235173177182 2.194714234876188E-202 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 47 2 81 2 2 false 0.6620370370370483 0.6620370370370483 1.2278945146862784E-16 localization_of_cell GO:0051674 12133 785 47 5 3467 24 1 false 0.6624161416478056 0.6624161416478056 0.0 transport GO:0006810 12133 2783 47 23 2833 23 1 false 0.6628755119421446 0.6628755119421446 1.147202604491021E-108 cell-substrate_adherens_junction GO:0005924 12133 125 47 1 188 1 2 false 0.6648936170212674 0.6648936170212674 1.3846447149399673E-51 sequence-specific_DNA_binding GO:0043565 12133 1189 47 5 2091 9 1 false 0.6650172869889166 0.6650172869889166 0.0 actin_cytoskeleton_organization GO:0030036 12133 373 47 2 768 4 2 false 0.6661741392198718 0.6661741392198718 3.0657297438498186E-230 ferric_iron_transport GO:0015682 12133 24 47 1 36 1 2 false 0.6666666666666695 0.6666666666666695 7.989277111831545E-10 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 47 5 1007 5 2 false 0.6676794120268628 0.6676794120268628 1.4040993054667365E-118 mitochondrial_membrane GO:0031966 12133 359 47 1 1810 5 3 false 0.6693645417065379 0.6693645417065379 0.0 regulation_of_GTPase_activity GO:0043087 12133 277 47 1 1145 4 3 false 0.6702923858528408 0.6702923858528408 2.6919247726004267E-274 endomembrane_system GO:0012505 12133 1211 47 5 9983 46 1 false 0.6710108480279883 0.6710108480279883 0.0 ribosome_biogenesis GO:0042254 12133 144 47 3 243 5 1 false 0.671036189309024 0.671036189309024 8.984879194471426E-71 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 47 1 183 2 2 false 0.6721311475409307 0.6721311475409307 1.0111677973178846E-53 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 47 7 4298 36 4 false 0.6727221869170212 0.6727221869170212 0.0 regulation_of_cell_death GO:0010941 12133 1062 47 4 6437 27 2 false 0.6730407051625651 0.6730407051625651 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 47 3 147 3 1 false 0.6738530650805338 0.6738530650805338 1.843896992838607E-23 response_to_inorganic_substance GO:0010035 12133 277 47 1 2369 9 1 false 0.6740931533184193 0.6740931533184193 0.0 mitochondrion_organization GO:0007005 12133 215 47 1 2031 10 1 false 0.674226160793816 0.674226160793816 4.082912305313268E-297 adenyl_ribonucleotide_binding GO:0032559 12133 1231 47 6 1645 8 2 false 0.6745548630715769 0.6745548630715769 0.0 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 47 5 1006 5 2 false 0.674638232892963 0.674638232892963 2.1893990019353197E-116 adenyl_nucleotide_binding GO:0030554 12133 1235 47 6 1650 8 1 false 0.6749460680970498 0.6749460680970498 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 47 2 129 3 1 false 0.6781038271379052 0.6781038271379052 8.751505837166389E-37 acid-amino_acid_ligase_activity GO:0016881 12133 351 47 5 379 5 1 false 0.6798574075111385 0.6798574075111385 5.324332733169013E-43 immunoglobulin_production GO:0002377 12133 64 47 1 94 1 1 false 0.68085106382981 0.68085106382981 3.0952886871689963E-25 mitochondrial_transport GO:0006839 12133 124 47 1 2454 22 2 false 0.6820189775921319 0.6820189775921319 1.607876790046367E-212 organelle_assembly GO:0070925 12133 210 47 1 2677 14 2 false 0.6822908036533111 0.6822908036533111 7.5039E-319 response_to_metal_ion GO:0010038 12133 189 47 1 277 1 1 false 0.6823104693141068 0.6823104693141068 1.2236423246824455E-74 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 47 2 185 2 1 false 0.6831962397181021 0.6831962397181021 1.2806047113744547E-36 protein_modification_by_small_protein_removal GO:0070646 12133 77 47 1 645 9 1 false 0.6839320784299717 0.6839320784299717 7.565398504158586E-102 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 47 5 1002 5 3 false 0.6845391878397185 0.6845391878397185 5.68242981185093E-113 regulation_of_alternative_mRNA_splicing,_via_spliceosome GO:0000381 12133 16 47 1 37 2 2 false 0.6846846846846875 0.6846846846846875 7.76652299088412E-11 myeloid_cell_differentiation GO:0030099 12133 237 47 1 2177 10 2 false 0.6849837778643912 0.6849837778643912 0.0 positive_regulation_of_catabolic_process GO:0009896 12133 137 47 1 3517 29 3 false 0.6855567534589284 0.6855567534589284 1.0965595914697655E-250 Golgi_membrane GO:0000139 12133 322 47 1 1835 6 3 false 0.6863394180544921 0.6863394180544921 0.0 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 47 3 1053 5 1 false 0.686498997974067 0.686498997974067 1.6418245301060377E-306 regulation_of_cytokine_production GO:0001817 12133 323 47 1 1562 5 2 false 0.6865090704865826 0.6865090704865826 0.0 transferase_activity GO:0016740 12133 1779 47 5 4901 15 1 false 0.6867145543270052 0.6867145543270052 0.0 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 47 1 1586 6 3 false 0.6874241817099958 0.6874241817099958 1.5665E-319 guanyl_nucleotide_binding GO:0019001 12133 450 47 2 1650 8 1 false 0.6875563359722685 0.6875563359722685 0.0 ameboidal_cell_migration GO:0001667 12133 185 47 1 734 4 1 false 0.6878923746429604 0.6878923746429604 3.1688746703355204E-179 S-adenosylmethionine-dependent_methyltransferase_activity GO:0008757 12133 87 47 1 126 1 1 false 0.6904761904761948 0.6904761904761948 1.8124217932719872E-33 cellular_ion_homeostasis GO:0006873 12133 478 47 2 575 2 2 false 0.6908226026360981 0.6908226026360981 1.064446434652655E-112 guanyl_ribonucleotide_binding GO:0032561 12133 450 47 2 1641 8 2 false 0.6909314039120336 0.6909314039120336 0.0 biological_regulation GO:0065007 12133 6908 47 30 10446 47 1 false 0.6916268640954847 0.6916268640954847 0.0 regulation_of_nervous_system_development GO:0051960 12133 381 47 1 1805 5 2 false 0.6948460875932139 0.6948460875932139 0.0 negative_regulation_of_cell_proliferation GO:0008285 12133 455 47 2 2949 15 3 false 0.6981726127258174 0.6981726127258174 0.0 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 47 2 129 3 1 false 0.6999834050540257 0.6999834050540257 2.4714073881998435E-36 cytokine_production GO:0001816 12133 362 47 1 4095 13 1 false 0.7003259155767496 0.7003259155767496 0.0 GTP_metabolic_process GO:0046039 12133 625 47 3 1193 6 3 false 0.7003697346604754 0.7003697346604754 0.0 single-organism_developmental_process GO:0044767 12133 2776 47 12 8064 38 2 false 0.7010960855160724 0.7010960855160724 0.0 transmembrane_transport GO:0055085 12133 728 47 3 7606 37 2 false 0.7014728536965038 0.7014728536965038 0.0 epithelial_cell_migration GO:0010631 12133 130 47 1 185 1 2 false 0.7027027027027377 0.7027027027027377 1.9916445787710798E-48 antigen_processing_and_presentation_of_peptide_or_polysaccharide_antigen_via_MHC_class_II GO:0002504 12133 84 47 1 185 2 1 false 0.7032902467685117 0.7032902467685117 7.577866882274746E-55 protein_homodimerization_activity GO:0042803 12133 471 47 1 1035 2 2 false 0.7032938076413167 0.7032938076413167 7.159384282986134E-309 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 47 1 361 3 1 false 0.7037065615217533 0.7037065615217533 4.560830022372086E-99 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 47 8 4456 34 4 false 0.7079754740451185 0.7079754740451185 0.0 endosomal_transport GO:0016197 12133 133 47 1 2454 22 2 false 0.708085253595358 0.708085253595358 7.966947585336105E-224 neuron_projection_development GO:0031175 12133 575 47 1 812 1 2 false 0.7081280788176632 0.7081280788176632 3.771933680434825E-212 somatic_diversification_of_immunoglobulins_involved_in_immune_response GO:0002208 12133 34 47 1 48 1 2 false 0.708333333333333 0.708333333333333 2.0733096446974964E-12 adenylate_cyclase_activity GO:0004016 12133 103 47 1 145 1 3 false 0.710344827586197 0.710344827586197 1.7288474062512548E-37 nitrogen_compound_transport GO:0071705 12133 428 47 3 2783 23 1 false 0.710377444549956 0.710377444549956 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 47 6 400 6 2 false 0.7106143107441765 0.7106143107441765 1.150456419433401E-36 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 47 7 3453 33 4 false 0.7114508648356137 0.7114508648356137 0.0 DNA_damage_checkpoint GO:0000077 12133 126 47 1 574 5 2 false 0.7118027251590315 0.7118027251590315 1.5833464450994651E-130 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 47 1 158 2 2 false 0.7121664113520566 0.7121664113520566 6.794891168245598E-47 positive_regulation_of_cellular_component_movement GO:0051272 12133 216 47 1 3234 18 3 false 0.7128228229531344 0.7128228229531344 0.0 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 47 5 803 7 1 false 0.7138644380897674 0.7138644380897674 1.0286714317927864E-202 dephosphorylation GO:0016311 12133 328 47 1 2776 10 1 false 0.7162251281712066 0.7162251281712066 0.0 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 47 7 3780 35 4 false 0.7172358792894359 0.7172358792894359 0.0 cellular_component_biogenesis GO:0044085 12133 1525 47 9 3839 25 1 false 0.7176907124792116 0.7176907124792116 0.0 positive_regulation_of_cell_activation GO:0050867 12133 215 47 1 3002 17 3 false 0.7182764355113627 0.7182764355113627 0.0 hemostasis GO:0007599 12133 447 47 2 527 2 1 false 0.7191939452097564 0.7191939452097564 7.174896528140087E-97 mitochondrial_envelope GO:0005740 12133 378 47 1 803 2 2 false 0.7201889423392217 0.7201889423392217 2.632819629334664E-240 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 47 1 134 2 2 false 0.7211311861743613 0.7211311861743613 8.460684206886756E-40 chromatin_modification GO:0016568 12133 458 47 2 539 2 1 false 0.7217896283219056 0.7217896283219056 1.802023694196357E-98 cytoplasm GO:0005737 12133 6938 47 34 9083 46 1 false 0.7223024594409865 0.7223024594409865 0.0 histone_mRNA_metabolic_process GO:0008334 12133 27 47 1 573 26 1 false 0.7230355468008396 0.7230355468008396 6.871324608301151E-47 organ_development GO:0048513 12133 1929 47 7 3099 12 2 false 0.7231630642507658 0.7231630642507658 0.0 regulation_of_stress-activated_protein_kinase_signaling_cascade GO:0070302 12133 147 47 1 765 6 3 false 0.7233531301883886 0.7233531301883886 7.281108340064304E-162 nuclear_hormone_receptor_binding GO:0035257 12133 104 47 2 122 2 1 false 0.7256469313101672 0.7256469313101672 6.677251530520905E-22 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 47 8 4582 35 3 false 0.7259098894539493 0.7259098894539493 0.0 response_to_organic_nitrogen GO:0010243 12133 519 47 2 1787 8 3 false 0.7259146241072608 0.7259146241072608 0.0 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 47 2 1211 6 2 false 0.7262630714498959 0.7262630714498959 0.0 multicellular_organismal_development GO:0007275 12133 3069 47 10 4373 15 2 false 0.727199382165892 0.727199382165892 0.0 actin_cytoskeleton GO:0015629 12133 327 47 1 1430 5 1 false 0.7275449693533956 0.7275449693533956 0.0 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 47 2 3447 12 2 false 0.7285660475688369 0.7285660475688369 0.0 cell_development GO:0048468 12133 1255 47 4 3306 12 4 false 0.7291431056618568 0.7291431056618568 0.0 regulation_of_systemic_arterial_blood_pressure GO:0003073 12133 56 47 1 117 2 1 false 0.7303271441202416 0.7303271441202416 9.090542259133476E-35 erythrocyte_homeostasis GO:0034101 12133 95 47 2 111 2 1 false 0.7313677313677038 0.7313677313677038 1.225965890705918E-19 axon_guidance GO:0007411 12133 295 47 1 611 2 2 false 0.7329290869580484 0.7329290869580484 5.229199602535248E-183 regulation_of_cell_activation GO:0050865 12133 303 47 1 6351 27 2 false 0.7335748878927446 0.7335748878927446 0.0 regulation_of_multicellular_organismal_development GO:2000026 12133 953 47 3 3481 13 3 false 0.7350081975936317 0.7350081975936317 0.0 ubiquitin_binding GO:0043130 12133 61 47 2 71 2 1 false 0.7364185110663888 0.7364185110663888 2.1657301017057942E-12 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 47 2 971 30 2 false 0.7377110043335127 0.7377110043335127 1.7939571902377886E-121 phagocytosis GO:0006909 12133 149 47 1 2417 21 2 false 0.7386630254166676 0.7386630254166676 3.130675140672653E-242 regulation_of_protein_import_into_nucleus GO:0042306 12133 121 47 1 248 2 4 false 0.7387684471724912 0.7387684471724912 4.6955049394038436E-74 regulation_of_molecular_function GO:0065009 12133 2079 47 8 10494 47 2 false 0.7397666664280611 0.7397666664280611 0.0 regulation_of_catabolic_process GO:0009894 12133 554 47 3 5455 37 2 false 0.7405816640627346 0.7405816640627346 0.0 somatic_recombination_of_immunoglobulin_gene_segments GO:0016447 12133 40 47 1 54 1 2 false 0.7407407407407403 0.7407407407407403 3.081310036937439E-13 Ras_protein_signal_transduction GO:0007265 12133 365 47 2 547 3 1 false 0.7419619945323741 0.7419619945323741 2.1494674666292624E-150 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 47 4 2780 10 2 false 0.74492690239794 0.74492690239794 0.0 neuron_projection_morphogenesis GO:0048812 12133 475 47 1 637 1 2 false 0.7456828885398858 0.7456828885398858 3.7535814082411355E-156 repressing_transcription_factor_binding GO:0070491 12133 207 47 1 715 4 1 false 0.7460549279514712 0.7460549279514712 4.3536836236667346E-186 regulation_of_adenylate_cyclase_activity GO:0045761 12133 103 47 1 138 1 4 false 0.7463768115942113 0.7463768115942113 1.4792034822830027E-33 angiogenesis GO:0001525 12133 300 47 1 2776 12 3 false 0.7472335653749982 0.7472335653749982 0.0 double-stranded_RNA_binding GO:0003725 12133 42 47 1 763 24 1 false 0.7485173383727974 0.7485173383727974 3.809412344480898E-70 mitochondrion GO:0005739 12133 1138 47 5 8213 44 2 false 0.7485940165044364 0.7485940165044364 0.0 monovalent_inorganic_cation_transport GO:0015672 12133 302 47 1 606 2 1 false 0.748760330578956 0.748760330578956 1.1660817479890875E-181 purine_nucleoside_metabolic_process GO:0042278 12133 1054 47 5 1257 6 2 false 0.749387902352061 0.749387902352061 1.399683863089717E-240 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 47 1 527 2 2 false 0.749525616698638 0.749525616698638 6.55805140577772E-158 maturation_of_SSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000462 12133 7 47 2 8 2 1 false 0.7500000000000001 0.7500000000000001 0.12499999999999997 GTP_catabolic_process GO:0006184 12133 614 47 3 957 5 4 false 0.7520983726720949 0.7520983726720949 2.3934835856107606E-270 regulation_of_Ras_GTPase_activity GO:0032318 12133 179 47 1 357 2 2 false 0.7521008403362168 0.7521008403362168 8.083441090582102E-107 hydrolase_activity GO:0016787 12133 2556 47 7 4901 15 1 false 0.7531781698026757 0.7531781698026757 0.0 steroid_metabolic_process GO:0008202 12133 182 47 1 5438 41 2 false 0.7536326674783168 0.7536326674783168 0.0 cysteine-type_peptidase_activity GO:0008234 12133 295 47 1 586 2 1 false 0.7538286514397947 0.7538286514397947 1.2148857586981575E-175 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_II GO:0002495 12133 83 47 1 164 2 2 false 0.7575938949573486 0.7575938949573486 6.958070805209033E-49 regulation_of_cell_morphogenesis GO:0022604 12133 267 47 1 1647 8 3 false 0.7578688740484412 0.7578688740484412 3.9027101E-316 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 47 3 956 5 2 false 0.7581211068017877 0.7581211068017877 3.936677708897206E-269 regulation_of_biological_process GO:0050789 12133 6622 47 28 10446 47 2 false 0.7588947888450659 0.7588947888450659 0.0 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 47 11 207 11 1 false 0.7589852188445828 0.7589852188445828 3.3148479610294504E-10 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 47 1 660 1 2 false 0.7606060606062449 0.7606060606062449 4.8010140095396714E-157 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 47 4 10311 47 3 false 0.761794725552789 0.761794725552789 0.0 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 47 8 645 9 1 false 0.7619037085595555 0.7619037085595555 7.3138241320053254E-93 neuron_projection GO:0043005 12133 534 47 1 1043 2 2 false 0.762080812950947 0.762080812950947 5.7946905775E-313 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 47 1 1265 6 3 false 0.7625252483902081 0.7625252483902081 1.9379490968147627E-283 lymphocyte_mediated_immunity GO:0002449 12133 139 47 1 182 1 1 false 0.7637362637362488 0.7637362637362488 8.778235670388515E-43 regulation_of_anatomical_structure_size GO:0090066 12133 256 47 1 2082 11 1 false 0.7647084798356788 0.7647084798356788 0.0 regulation_of_localization GO:0032879 12133 1242 47 5 7621 38 2 false 0.7649044918837498 0.7649044918837498 0.0 regulation_of_system_process GO:0044057 12133 373 47 1 2254 8 2 false 0.7653575197447782 0.7653575197447782 0.0 microtubule_organizing_center GO:0005815 12133 413 47 1 1076 3 2 false 0.7664671602366018 0.7664671602366018 2.6476518998275E-310 interspecies_interaction_between_organisms GO:0044419 12133 417 47 6 1180 20 1 false 0.766531019353409 0.766531019353409 0.0 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 47 22 5532 42 4 false 0.7678094475715396 0.7678094475715396 0.0 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 47 1 3568 18 3 false 0.7686337874727969 0.7686337874727969 0.0 endothelial_cell_migration GO:0043542 12133 100 47 1 130 1 1 false 0.7692307692307458 0.7692307692307458 3.8279880512589226E-30 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 47 2 4239 25 3 false 0.7698316956232023 0.7698316956232023 0.0 cation_transmembrane_transporter_activity GO:0008324 12133 365 47 1 701 2 2 false 0.7706134094151502 0.7706134094151502 5.744660517109641E-210 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_II GO:0019886 12133 80 47 1 154 2 2 false 0.7707325354383334 0.7707325354383334 7.662175327238918E-46 protein_oligomerization GO:0051259 12133 288 47 1 743 3 1 false 0.7709372214152936 0.7709372214152936 1.196705520432063E-214 nucleic_acid_transport GO:0050657 12133 124 47 3 135 3 1 false 0.7733862018230198 0.7733862018230198 2.2345648964967124E-16 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 47 1 1206 6 3 false 0.7751321315136926 0.7751321315136926 5.7559641067065754E-275 ribonucleotide_biosynthetic_process GO:0009260 12133 275 47 1 1250 6 3 false 0.7755638769665476 0.7755638769665476 3.3374763917028038E-285 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 47 2 185 2 1 false 0.7757344300823621 0.7757344300823621 5.464989090238489E-29 regulation_of_ion_transport GO:0043269 12133 307 47 1 1393 6 2 false 0.7761555849251545 0.7761555849251545 3.368915E-318 microtubule_cytoskeleton_organization GO:0000226 12133 259 47 1 831 4 2 false 0.7762540022588194 0.7762540022588194 4.0880234187670296E-223 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 47 1 90 1 3 false 0.7777777777777884 0.7777777777777884 1.9615250672171495E-20 regulation_of_action_potential GO:0001508 12133 114 47 1 216 2 1 false 0.7781653746768953 0.7781653746768953 2.440510173476933E-64 immune_system_development GO:0002520 12133 521 47 2 3460 18 2 false 0.778674861657495 0.778674861657495 0.0 glycosyl_compound_metabolic_process GO:1901657 12133 1093 47 5 7599 44 2 false 0.778734330746981 0.778734330746981 0.0 positive_regulation_of_transport GO:0051050 12133 413 47 2 4769 32 3 false 0.7787397471557318 0.7787397471557318 0.0 spliceosomal_snRNP_assembly GO:0000387 12133 30 47 1 259 12 2 false 0.7794757839799817 0.7794757839799817 6.073894661120439E-40 chromatin_binding GO:0003682 12133 309 47 1 8962 43 1 false 0.7796118845326572 0.7796118845326572 0.0 regulation_of_stress-activated_MAPK_cascade GO:0032872 12133 146 47 1 463 4 3 false 0.7815737533688549 0.7815737533688549 1.1657182873431035E-124 regulation_of_biosynthetic_process GO:0009889 12133 3012 47 19 5483 38 2 false 0.781825600659311 0.781825600659311 0.0 heart_development GO:0007507 12133 343 47 1 2876 12 3 false 0.7828287833104746 0.7828287833104746 0.0 positive_regulation_of_apoptotic_process GO:0043065 12133 362 47 1 1377 5 3 false 0.7829635044080008 0.7829635044080008 0.0 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 47 1 1393 5 3 false 0.7848498932238399 0.7848498932238399 0.0 muscle_organ_development GO:0007517 12133 308 47 1 1966 9 2 false 0.7849560931084063 0.7849560931084063 0.0 protein_kinase_binding GO:0019901 12133 341 47 2 384 2 1 false 0.7883213664057611 0.7883213664057611 5.20098898434574E-58 regulation_of_hydrolase_activity GO:0051336 12133 821 47 2 3094 10 2 false 0.7892631989709247 0.7892631989709247 0.0 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 47 1 163 2 1 false 0.7898204953418904 0.7898204953418904 2.2957799692832176E-48 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 47 3 381 6 2 false 0.789924074960594 0.789924074960594 4.820433761728018E-112 Golgi_vesicle_transport GO:0048193 12133 170 47 1 2599 23 3 false 0.7904383600490107 0.7904383600490107 6.28157499519694E-272 small_conjugating_protein_ligase_activity GO:0019787 12133 335 47 5 351 5 1 false 0.7908466482074769 0.7908466482074769 5.577217121688537E-28 cellular_homeostasis GO:0019725 12133 585 47 2 7566 37 2 false 0.7919222099494437 0.7919222099494437 0.0 endosomal_part GO:0044440 12133 257 47 1 7185 43 3 false 0.7921477807531734 0.7921477807531734 0.0 regulation_of_mRNA_stability GO:0043488 12133 33 47 2 37 2 1 false 0.792792792792794 0.792792792792794 1.5141191611779804E-5 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 47 1 116 2 3 false 0.7934032983508316 0.7934032983508316 2.4978330889301296E-34 cell_cycle_arrest GO:0007050 12133 202 47 1 998 7 2 false 0.7957569822363786 0.7957569822363786 1.5077994882682823E-217 negative_regulation_of_cell_death GO:0060548 12133 567 47 2 3054 15 3 false 0.797705454823619 0.797705454823619 0.0 mitotic_cell_cycle GO:0000278 12133 625 47 4 1295 10 1 false 0.799080065613973 0.799080065613973 0.0 spindle_assembly_checkpoint GO:0071173 12133 36 47 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 regulation_of_cAMP_biosynthetic_process GO:0030817 12133 124 47 1 155 1 4 false 0.8000000000000121 0.8000000000000121 2.5860077232155615E-33 regulation_of_neurogenesis GO:0050767 12133 344 47 1 1039 4 4 false 0.8003670652576513 0.8003670652576513 1.1807712079388562E-285 transcription_cofactor_activity GO:0003712 12133 456 47 4 482 4 2 false 0.800500170559153 0.800500170559153 1.3948726648763881E-43 nuclear_division GO:0000280 12133 326 47 3 351 3 1 false 0.8006549324604972 0.8006549324604972 8.671827254018066E-39 synapse GO:0045202 12133 368 47 1 10701 46 1 false 0.8007516611888835 0.8007516611888835 0.0 signal_transducer_activity GO:0004871 12133 1070 47 3 3547 13 2 false 0.8016196654685556 0.8016196654685556 0.0 coated_vesicle_membrane GO:0030662 12133 122 47 1 368 4 2 false 0.8019342154161937 0.8019342154161937 6.74679218492705E-101 clathrin-coated_vesicle GO:0030136 12133 162 47 1 202 1 1 false 0.8019801980198291 0.8019801980198291 3.1333299685548734E-43 negative_regulation_of_transport GO:0051051 12133 243 47 1 4618 30 3 false 0.8034642040582316 0.8034642040582316 0.0 envelope GO:0031975 12133 641 47 2 9983 46 1 false 0.8043752517939099 0.8043752517939099 0.0 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 47 1 1279 6 3 false 0.8068713872237524 0.8068713872237524 9.116385096369177E-305 isotype_switching GO:0045190 12133 34 47 1 42 1 2 false 0.8095238095238179 0.8095238095238179 8.472408985887957E-9 cellular_cation_homeostasis GO:0030003 12133 289 47 1 513 2 2 false 0.8098196881091319 0.8098196881091319 6.525965777081911E-152 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 47 5 6622 28 1 false 0.8104538265493613 0.8104538265493613 0.0 signal_transduction GO:0007165 12133 3547 47 13 6702 28 4 false 0.8105592119073366 0.8105592119073366 0.0 spindle GO:0005819 12133 221 47 1 4762 35 4 false 0.8116264874411236 0.8116264874411236 0.0 protein_complex_binding GO:0032403 12133 306 47 1 6397 34 1 false 0.8119401036463867 0.8119401036463867 0.0 neurogenesis GO:0022008 12133 940 47 3 2425 10 2 false 0.8124714292898381 0.8124714292898381 0.0 coated_vesicle GO:0030135 12133 202 47 1 712 5 1 false 0.8124907438678091 0.8124907438678091 1.1363731817938802E-183 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 47 2 1804 9 2 false 0.8141735601500875 0.8141735601500875 0.0 nucleotide_biosynthetic_process GO:0009165 12133 322 47 1 1318 6 2 false 0.8144502130323884 0.8144502130323884 2.1862113E-317 defense_response_to_virus GO:0051607 12133 160 47 1 1130 11 3 false 0.8150237705738765 0.8150237705738765 2.076664675339186E-199 leukocyte_migration GO:0050900 12133 224 47 1 1975 14 2 false 0.815713177881031 0.815713177881031 1.7898344026900835E-302 cell_projection_morphogenesis GO:0048858 12133 541 47 1 946 2 3 false 0.816973723950766 0.816973723950766 1.1683643564827775E-279 regulation_of_GTP_catabolic_process GO:0033124 12133 279 47 1 642 3 3 false 0.8198852142168194 0.8198852142168194 4.2701237450964594E-190 regulation_of_locomotion GO:0040012 12133 398 47 1 6714 28 2 false 0.8199650395219539 0.8199650395219539 0.0 response_to_hormone_stimulus GO:0009725 12133 611 47 2 1784 8 2 false 0.8201103983795826 0.8201103983795826 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 47 3 6358 27 2 false 0.8201158124818555 0.8201158124818555 0.0 adaptive_immune_response GO:0002250 12133 174 47 1 1006 9 1 false 0.8203374704248279 0.8203374704248279 1.8321069442753992E-200 regulation_of_response_to_external_stimulus GO:0032101 12133 314 47 1 2524 13 2 false 0.8229791854882902 0.8229791854882902 0.0 histone_lysine_methylation GO:0034968 12133 66 47 1 80 1 1 false 0.8249999999999986 0.8249999999999986 6.630630379305838E-16 positive_regulation_of_mitochondrial_membrane_permeability GO:0035794 12133 38 47 1 46 1 1 false 0.8260869565217287 0.8260869565217287 3.832404138206993E-9 system_development GO:0048731 12133 2686 47 9 3304 12 2 false 0.8281744270985537 0.8281744270985537 0.0 generation_of_neurons GO:0048699 12133 883 47 3 940 3 1 false 0.8287220853101755 0.8287220853101755 7.799501535546468E-93 double-strand_break_repair GO:0006302 12133 109 47 1 368 5 1 false 0.8292960688205664 0.8292960688205664 1.714085470943145E-96 substrate-specific_transporter_activity GO:0022892 12133 620 47 1 746 1 1 false 0.8310991957102674 0.8310991957102674 1.886990037563331E-146 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 47 1 630 4 2 false 0.833460566240513 0.833460566240513 4.4826406352842784E-178 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 47 21 4544 41 3 false 0.8349457138490727 0.8349457138490727 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 47 2 165 2 2 false 0.8370288248337823 0.8370288248337823 1.3866478491946915E-20 large_ribosomal_subunit GO:0015934 12133 73 47 6 132 13 1 false 0.8394708405381374 0.8394708405381374 5.5437540818743186E-39 cell-cell_junction_organization GO:0045216 12133 152 47 1 181 1 1 false 0.8397790055249296 0.8397790055249296 3.1886200066761254E-34 regulation_of_protein_localization GO:0032880 12133 349 47 2 2148 19 2 false 0.8398870538543949 0.8398870538543949 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 47 3 214 3 1 false 0.8403267426814965 0.8403267426814965 7.108512362452622E-20 regulation_of_cellular_process GO:0050794 12133 6304 47 27 9757 46 2 false 0.8403378071755011 0.8403378071755011 0.0 cell-cell_signaling GO:0007267 12133 859 47 2 3969 14 2 false 0.8403939289052045 0.8403939289052045 0.0 cellular_metal_ion_homeostasis GO:0006875 12133 259 47 1 308 1 2 false 0.8409090909089498 0.8409090909089498 3.9623191237847456E-58 nucleoplasm_part GO:0044451 12133 805 47 6 2767 27 2 false 0.8422494493515604 0.8422494493515604 0.0 metal_ion_homeostasis GO:0055065 12133 278 47 1 330 1 1 false 0.8424242424241729 0.8424242424241729 6.131976736615521E-62 nuclear_transport GO:0051169 12133 331 47 4 1148 19 1 false 0.8442209369500046 0.8442209369500046 1.3196682196913852E-298 brain_development GO:0007420 12133 420 47 1 2904 12 3 false 0.8471779350561853 0.8471779350561853 0.0 lymphocyte_activation GO:0046649 12133 403 47 1 475 1 1 false 0.8484210526316471 0.8484210526316471 3.3805466364584557E-87 regulation_of_cellular_localization GO:0060341 12133 603 47 2 6869 37 3 false 0.8484701601062195 0.8484701601062195 0.0 androgen_receptor_signaling_pathway GO:0030521 12133 62 47 1 102 2 1 false 0.8485730926033468 0.8485730926033468 2.6706454874295595E-29 transcription_corepressor_activity GO:0003714 12133 180 47 1 479 4 2 false 0.8493230325310998 0.8493230325310998 5.2319775680795235E-137 somatic_recombination_of_immunoglobulin_genes_involved_in_immune_response GO:0002204 12133 34 47 1 40 1 2 false 0.8500000000000089 0.8500000000000089 2.6052657631605196E-7 microtubule-based_process GO:0007017 12133 378 47 1 7541 37 1 false 0.8515392737586487 0.8515392737586487 0.0 homeostatic_process GO:0042592 12133 990 47 4 2082 11 1 false 0.8526351540531276 0.8526351540531276 0.0 regulation_of_intracellular_transport GO:0032386 12133 276 47 2 1731 20 3 false 0.8529699419963483 0.8529699419963483 0.0 androgen_receptor_binding GO:0050681 12133 38 47 1 62 2 1 false 0.8540454785827765 0.8540454785827765 1.0311688046013243E-17 negative_regulation_of_gene_expression GO:0010629 12133 817 47 6 3906 39 3 false 0.85500425232106 0.85500425232106 0.0 receptor-mediated_endocytosis GO:0006898 12133 157 47 1 411 4 1 false 0.8554495825002059 0.8554495825002059 4.873503831957431E-118 striated_muscle_cell_differentiation GO:0051146 12133 203 47 2 267 3 1 false 0.8562511855215267 0.8562511855215267 2.4098375851666058E-63 cation_homeostasis GO:0055080 12133 330 47 1 532 2 1 false 0.8562720360227958 0.8562720360227958 1.1320770482912473E-152 regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030802 12133 143 47 1 167 1 3 false 0.856287425149713 0.856287425149713 1.5904574919997758E-29 positive_regulation_of_intracellular_transport GO:0032388 12133 126 47 1 1370 20 3 false 0.8568358680342374 0.8568358680342374 5.304932497681123E-182 spliceosomal_complex_assembly GO:0000245 12133 38 47 1 259 12 2 false 0.8576209077128709 0.8576209077128709 1.791986159229858E-46 cellular_component_assembly GO:0022607 12133 1392 47 7 3836 25 2 false 0.8592859554854808 0.8592859554854808 0.0 metal_ion_binding GO:0046872 12133 2699 47 7 2758 7 1 false 0.8593853723950909 0.8593853723950909 2.6200760259069314E-123 epithelial_cell_differentiation GO:0030855 12133 397 47 1 2228 10 2 false 0.8600980779079048 0.8600980779079048 0.0 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 47 1 1088 6 3 false 0.8618167303416443 0.8618167303416443 1.7563474810306042E-279 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 47 1 450 5 2 false 0.8630918634058243 0.8630918634058243 8.40005869125793E-123 regulation_of_mRNA_splicing,_via_spliceosome GO:0048024 12133 32 47 1 231 13 3 false 0.86398344012693 0.86398344012693 5.789429371590664E-40 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 47 1 365 1 1 false 0.8657534246575868 0.8657534246575868 4.982755146780477E-62 organelle_envelope GO:0031967 12133 629 47 2 7756 42 3 false 0.8658097664131863 0.8658097664131863 0.0 viral_genome_replication GO:0019079 12133 55 47 1 557 19 2 false 0.8659818117090146 0.8659818117090146 1.9020892479615726E-77 cell_cycle_checkpoint GO:0000075 12133 202 47 2 217 2 1 false 0.8662314388120638 0.8662314388120638 1.925703524045096E-23 catalytic_step_2_spliceosome GO:0071013 12133 76 47 3 151 8 3 false 0.8664114683148082 0.8664114683148082 5.422089502503699E-45 methyltransferase_activity GO:0008168 12133 126 47 1 199 2 2 false 0.8666057560529297 0.8666057560529297 2.689097193899432E-56 translation_elongation_factor_activity GO:0003746 12133 22 47 1 180 15 2 false 0.8701844392565588 0.8701844392565588 1.0368938565383413E-28 cellular_response_to_stimulus GO:0051716 12133 4236 47 17 7871 37 2 false 0.8702350056245979 0.8702350056245979 0.0 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 47 1 3785 24 2 false 0.8704271782368036 0.8704271782368036 0.0 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 47 3 1304 4 1 false 0.8708008960068578 0.8708008960068578 1.004636319027547E-252 axonogenesis GO:0007409 12133 421 47 1 483 1 2 false 0.8716356107660534 0.8716356107660534 7.423880338325494E-80 response_to_stimulus GO:0050896 12133 5200 47 20 10446 47 1 false 0.8728398165582462 0.8728398165582462 0.0 death GO:0016265 12133 1528 47 5 8052 38 1 false 0.8730086870912704 0.8730086870912704 0.0 muscle_contraction GO:0006936 12133 220 47 1 252 1 1 false 0.8730158730158051 0.8730158730158051 2.9388717314840356E-41 tissue_development GO:0009888 12133 1132 47 3 3099 12 1 false 0.873218582300856 0.873218582300856 0.0 DNA_integrity_checkpoint GO:0031570 12133 130 47 1 202 2 1 false 0.8740948721737103 0.8740948721737103 1.23666756413938E-56 Fc_receptor_signaling_pathway GO:0038093 12133 76 47 1 188 4 1 false 0.8767814606968649 0.8767814606968649 1.381050418692459E-54 nuclear_envelope GO:0005635 12133 258 47 1 3962 31 3 false 0.8770064351028051 0.8770064351028051 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 47 2 1096 9 2 false 0.8781230664252223 0.8781230664252223 7.137372224746455E-307 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 47 6 1218 6 2 false 0.8783281168061138 0.8783281168061138 3.12960829510125E-54 leukocyte_mediated_immunity GO:0002443 12133 182 47 1 445 4 1 false 0.8791346209325446 0.8791346209325446 4.746005199012963E-130 molecular_transducer_activity GO:0060089 12133 1070 47 3 10257 47 1 false 0.8813696387472636 0.8813696387472636 0.0 small_molecule_metabolic_process GO:0044281 12133 2423 47 6 2877 8 1 false 0.8816009777594626 0.8816009777594626 0.0 central_nervous_system_development GO:0007417 12133 571 47 1 2686 9 2 false 0.8840517960527852 0.8840517960527852 0.0 protein_methylation GO:0006479 12133 98 47 1 149 2 2 false 0.8843642300017935 0.8843642300017935 3.8389402861551994E-41 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 47 7 3972 35 4 false 0.8847880581700226 0.8847880581700226 0.0 receptor_binding GO:0005102 12133 918 47 3 6397 34 1 false 0.8848321500921907 0.8848321500921907 0.0 signaling GO:0023052 12133 3878 47 14 10446 47 1 false 0.8852581937102753 0.8852581937102753 0.0 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 47 1 71 1 3 false 0.8873239436619828 0.8873239436619828 9.399268641403064E-11 organelle_membrane GO:0031090 12133 1619 47 5 9319 43 3 false 0.8897316800405732 0.8897316800405732 0.0 positive_regulation_of_cell_death GO:0010942 12133 383 47 1 3330 18 3 false 0.8897843564099579 0.8897843564099579 0.0 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 47 1 2896 12 3 false 0.8929043847712013 0.8929043847712013 0.0 positive_regulation_of_leukocyte_activation GO:0002696 12133 206 47 1 756 7 4 false 0.8932576270408341 0.8932576270408341 1.5163059036704027E-191 peptidyl-amino_acid_modification GO:0018193 12133 623 47 2 2370 13 1 false 0.8937346580945104 0.8937346580945104 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 47 7 4103 40 3 false 0.8940774508529787 0.8940774508529787 0.0 cell_morphogenesis GO:0000902 12133 766 47 2 810 2 1 false 0.8942452959754951 0.8942452959754951 9.285456073507826E-74 cell_death GO:0008219 12133 1525 47 5 7542 37 2 false 0.894559670316047 0.894559670316047 0.0 Fc_receptor_mediated_stimulatory_signaling_pathway GO:0002431 12133 76 47 1 178 4 1 false 0.894897570530945 0.894897570530945 2.9073989409378337E-52 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 47 19 4972 37 3 false 0.8951137318624486 0.8951137318624486 0.0 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 47 1 381 3 2 false 0.8954803958769892 0.8954803958769892 8.855041133991382E-114 protein_localization_to_mitochondrion GO:0070585 12133 67 47 1 516 16 1 false 0.8957339892748604 0.8957339892748604 5.765661430685337E-86 developmental_process GO:0032502 12133 3447 47 12 10446 47 1 false 0.8959220626047966 0.8959220626047966 0.0 response_to_wounding GO:0009611 12133 905 47 3 2540 13 1 false 0.8960504371199145 0.8960504371199145 0.0 response_to_oxygen-containing_compound GO:1901700 12133 864 47 2 2369 9 1 false 0.8964998616155051 0.8964998616155051 0.0 adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002460 12133 156 47 1 174 1 1 false 0.8965517241379637 0.8965517241379637 7.444259624063543E-25 cell_part_morphogenesis GO:0032990 12133 551 47 1 810 2 1 false 0.898026827816791 0.898026827816791 1.1709501739830369E-219 positive_regulation_of_protein_transport GO:0051222 12133 154 47 1 1301 18 3 false 0.8980877225409989 0.8980877225409989 9.736449433094532E-205 cell_differentiation GO:0030154 12133 2154 47 10 2267 11 1 false 0.899025221435007 0.899025221435007 2.602261335719434E-194 positive_regulation_of_intracellular_protein_transport GO:0090316 12133 92 47 1 737 17 4 false 0.8990861602135869 0.8990861602135869 7.301092489476398E-120 protein_complex_biogenesis GO:0070271 12133 746 47 3 1525 9 1 false 0.8997115328560774 0.8997115328560774 0.0 protein_kinase_activity GO:0004672 12133 1014 47 3 1347 5 3 false 0.8997895755652886 0.8997895755652886 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 47 10 2805 10 1 false 0.901141542748375 0.901141542748375 1.0460685646312495E-69 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 47 1 4251 34 6 false 0.902313344686763 0.902313344686763 0.0 protein_acetylation GO:0006473 12133 140 47 1 155 1 1 false 0.9032258064516349 0.9032258064516349 3.675799410957308E-21 chromosome_organization GO:0051276 12133 689 47 2 2031 10 1 false 0.903246582286495 0.903246582286495 0.0 chemical_homeostasis GO:0048878 12133 677 47 2 990 4 1 false 0.9039996154767402 0.9039996154767402 1.9931274413677286E-267 regulation_of_catalytic_activity GO:0050790 12133 1692 47 5 6953 31 3 false 0.9044836706543555 0.9044836706543555 0.0 nucleoside-triphosphatase_activity GO:0017111 12133 1059 47 5 1080 5 1 false 0.9063189430130167 0.9063189430130167 1.2343281293318376E-44 regulation_of_protein_phosphorylation GO:0001932 12133 787 47 3 1444 8 3 false 0.907393268836388 0.907393268836388 0.0 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 47 6 378 6 1 false 0.9078751437642244 0.9078751437642244 2.5686196448553377E-13 anatomical_structure_morphogenesis GO:0009653 12133 1664 47 4 3447 12 2 false 0.9092108271099911 0.9092108271099911 0.0 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 47 2 614 2 1 false 0.910803385921994 0.910803385921994 4.862693095923331E-49 epithelium_development GO:0060429 12133 627 47 1 1132 3 1 false 0.9115083232271376 0.9115083232271376 0.0 purine_ribonucleotide_binding GO:0032555 12133 1641 47 8 1660 8 2 false 0.9118404836621758 0.9118404836621758 8.870449707822982E-45 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 47 2 86 3 2 false 0.9124487004104362 0.9124487004104362 1.0344828145516245E-17 regulation_of_cytoskeleton_organization GO:0051493 12133 250 47 1 955 8 2 false 0.9127143998519853 0.9127143998519853 1.2229840665192896E-237 regulation_of_leukocyte_activation GO:0002694 12133 278 47 1 948 7 3 false 0.9127327441530223 0.9127327441530223 2.7935655578419027E-248 regulation_of_JNK_cascade GO:0046328 12133 126 47 1 179 2 2 false 0.9135019772769651 0.9135019772769651 9.08597934181437E-47 macromolecule_modification GO:0043412 12133 2461 47 14 6052 44 1 false 0.9136334371548956 0.9136334371548956 0.0 synaptic_transmission GO:0007268 12133 515 47 1 923 3 2 false 0.9139821954818378 0.9139821954818378 2.6714189194289816E-274 internal_protein_amino_acid_acetylation GO:0006475 12133 128 47 1 140 1 1 false 0.914285714285699 0.914285714285699 1.3721041217101573E-17 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 47 5 1072 5 2 false 0.9143124268728643 0.9143124268728643 3.811291228230986E-41 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 47 7 3847 40 4 false 0.9151853032505857 0.9151853032505857 0.0 inflammatory_response GO:0006954 12133 381 47 1 1437 8 2 false 0.9155515927396656 0.9155515927396656 0.0 identical_protein_binding GO:0042802 12133 743 47 2 6397 34 1 false 0.918382438385584 0.918382438385584 0.0 Golgi_apparatus_part GO:0044431 12133 406 47 1 7185 43 3 false 0.918625417447448 0.918625417447448 0.0 protein_processing GO:0016485 12133 113 47 1 123 1 1 false 0.918699186991829 0.918699186991829 6.665856545071852E-15 neurological_system_process GO:0050877 12133 894 47 2 1272 4 1 false 0.9187487558591358 0.9187487558591358 0.0 adherens_junction GO:0005912 12133 181 47 1 197 1 1 false 0.9187817258882387 0.9187817258882387 7.602023639007691E-24 endosome GO:0005768 12133 455 47 1 8213 44 2 false 0.9190968617564027 0.9190968617564027 0.0 small_GTPase_binding GO:0031267 12133 126 47 1 137 1 1 false 0.9197080291970834 0.9197080291970834 1.8889221296599312E-16 nervous_system_development GO:0007399 12133 1371 47 3 2686 9 1 false 0.9203468349628141 0.9203468349628141 0.0 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 47 1 3799 39 1 false 0.9208404903438019 0.9208404903438019 0.0 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 47 2 78 2 1 false 0.9240759240759076 0.9240759240759076 1.3144749986854762E-5 organophosphate_metabolic_process GO:0019637 12133 1549 47 6 7521 45 2 false 0.9248213791699337 0.9248213791699337 0.0 somatic_diversification_of_immune_receptors_via_germline_recombination_within_a_single_locus GO:0002562 12133 50 47 1 54 1 2 false 0.9259259259259376 0.9259259259259376 3.162045337406044E-6 cell_junction GO:0030054 12133 588 47 1 10701 46 1 false 0.9261228477326771 0.9261228477326771 0.0 developmental_process_involved_in_reproduction GO:0003006 12133 340 47 1 3959 29 2 false 0.9267371196400669 0.9267371196400669 0.0 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 47 4 5183 27 2 false 0.9284248265358948 0.9284248265358948 0.0 regulation_of_anatomical_structure_morphogenesis GO:0022603 12133 528 47 1 2074 9 2 false 0.9293643712173411 0.9293643712173411 0.0 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 47 6 7451 44 1 false 0.9295526059784944 0.9295526059784944 0.0 cation_binding GO:0043169 12133 2758 47 7 4448 15 1 false 0.9302078080944365 0.9302078080944365 0.0 protein_dimerization_activity GO:0046983 12133 779 47 2 6397 34 1 false 0.9313925212167048 0.9313925212167048 0.0 response_to_external_stimulus GO:0009605 12133 1046 47 2 5200 20 1 false 0.9327527052394287 0.9327527052394287 0.0 perinuclear_region_of_cytoplasm GO:0048471 12133 416 47 1 5117 32 1 false 0.9342564096236301 0.9342564096236301 0.0 cation_transport GO:0006812 12133 606 47 2 833 4 1 false 0.9360578328622643 0.9360578328622643 4.047492354513465E-211 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 47 1 1379 5 2 false 0.9366576856232821 0.9366576856232821 0.0 neuron_development GO:0048666 12133 654 47 1 1313 4 2 false 0.9368304230130314 0.9368304230130314 0.0 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 47 1 4156 34 3 false 0.9368485108102484 0.9368485108102484 0.0 transmembrane_transporter_activity GO:0022857 12133 544 47 1 904 3 2 false 0.9371627373734877 0.9371627373734877 4.222056161945909E-263 purine-containing_compound_metabolic_process GO:0072521 12133 1232 47 6 5323 41 5 false 0.9376999838199764 0.9376999838199764 0.0 hemopoiesis GO:0030097 12133 462 47 1 491 1 1 false 0.9409368635436436 0.9409368635436436 1.8682876304369947E-47 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 47 4 1546 15 3 false 0.9415938703864316 0.9415938703864316 0.0 single_organism_signaling GO:0044700 12133 3878 47 14 8052 38 2 false 0.941845403603607 0.941845403603607 0.0 response_to_radiation GO:0009314 12133 293 47 1 676 5 1 false 0.9422814760086866 0.9422814760086866 4.1946042901139895E-200 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 47 1 147 3 1 false 0.9435859369728128 0.9435859369728128 3.485982605742994E-42 mRNA_transport GO:0051028 12133 106 47 2 124 3 1 false 0.9450735834698398 0.9450735834698398 4.872659948511352E-22 ribonucleoside_metabolic_process GO:0009119 12133 1071 47 5 1083 5 1 false 0.9457144270360025 0.9457144270360025 1.9559437642804265E-28 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 47 8 2560 19 2 false 0.9458515364362414 0.9458515364362414 0.0 neuron_part GO:0097458 12133 612 47 1 9983 46 1 false 0.9459003994263679 0.9459003994263679 0.0 lipid_biosynthetic_process GO:0008610 12133 360 47 1 4386 34 2 false 0.9462496697893885 0.9462496697893885 0.0 internal_peptidyl-lysine_acetylation GO:0018393 12133 124 47 1 131 1 2 false 0.9465648854961779 0.9465648854961779 8.960493506706349E-12 Fc-gamma_receptor_signaling_pathway GO:0038094 12133 72 47 1 76 1 1 false 0.9473684210526206 0.9473684210526206 7.79438414622254E-7 cell_projection GO:0042995 12133 976 47 2 9983 46 1 false 0.9476846921122479 0.9476846921122479 0.0 regulation_of_cell_motility GO:2000145 12133 370 47 1 831 5 3 false 0.9479664295242851 0.9479664295242851 3.695619588048616E-247 protein_phosphorylation GO:0006468 12133 1195 47 4 2577 14 2 false 0.9489563051767747 0.9489563051767747 0.0 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 47 6 5657 41 2 false 0.9496365439091415 0.9496365439091415 0.0 centrosome GO:0005813 12133 327 47 1 3226 28 2 false 0.9505036495593226 0.9505036495593226 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 47 5 1014 5 1 false 0.9515596164819137 0.9515596164819137 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 47 5 1014 5 1 false 0.9515596164819137 0.9515596164819137 3.301546202575714E-24 nucleocytoplasmic_transport GO:0006913 12133 327 47 4 331 4 1 false 0.9523181216616468 0.9523181216616468 2.036102168267257E-9 Ras_GTPase_binding GO:0017016 12133 120 47 1 126 1 1 false 0.9523809523809658 0.9523809523809658 2.030392220357244E-10 regulation_of_protein_transport GO:0051223 12133 261 47 1 1665 18 3 false 0.9543253185100347 0.9543253185100347 3.65102727546E-313 ncRNA_processing GO:0034470 12133 186 47 3 649 20 2 false 0.9561014408364155 0.9561014408364155 4.048832162241149E-168 embryo_development GO:0009790 12133 768 47 1 3347 12 3 false 0.9564497574647652 0.9564497574647652 0.0 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 47 2 1192 17 2 false 0.9567298292399611 0.9567298292399611 5.168872172755415E-294 intrinsic_to_membrane GO:0031224 12133 2375 47 1 2995 2 1 false 0.9572009907374975 0.9572009907374975 0.0 apoptotic_process GO:0006915 12133 1373 47 5 1385 5 1 false 0.9573623706560377 0.9573623706560377 1.0085392941984968E-29 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 47 1 73 1 1 false 0.9589041095890459 0.9589041095890459 1.607820438613435E-5 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 47 3 149 3 1 false 0.9600036277888687 0.9600036277888687 9.06947215672054E-5 cell_proliferation GO:0008283 12133 1316 47 3 8052 38 1 false 0.9603184496906376 0.9603184496906376 0.0 transcription,_DNA-dependent GO:0006351 12133 2643 47 20 4063 38 3 false 0.9605864604548732 0.9605864604548732 0.0 endopeptidase_activity GO:0004175 12133 470 47 1 586 2 1 false 0.9610863160350294 0.9610863160350294 5.73935751356398E-126 purine_nucleoside_binding GO:0001883 12133 1631 47 8 1639 8 1 false 0.961531589076234 0.961531589076234 7.876250956196666E-22 activation_of_adenylate_cyclase_activity GO:0007190 12133 50 47 1 52 1 1 false 0.9615384615384723 0.9615384615384723 7.54147812971345E-4 ion_transport GO:0006811 12133 833 47 4 2323 20 1 false 0.9629893316979802 0.9629893316979802 0.0 extracellular_region_part GO:0044421 12133 740 47 1 10701 46 2 false 0.9632476801153845 0.9632476801153845 0.0 cell_migration GO:0016477 12133 734 47 4 785 5 1 false 0.963517162018025 0.963517162018025 1.8763224028220524E-81 positive_regulation_of_cell_proliferation GO:0008284 12133 558 47 1 3155 17 3 false 0.9637760374575256 0.9637760374575256 0.0 extracellular_region GO:0005576 12133 1152 47 2 10701 46 1 false 0.9655328523280161 0.9655328523280161 0.0 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 47 17 3120 25 4 false 0.9657136122890002 0.9657136122890002 0.0 striated_muscle_tissue_development GO:0014706 12133 285 47 1 295 1 1 false 0.9661016949152815 0.9661016949152815 8.482306621073292E-19 vesicle-mediated_transport GO:0016192 12133 895 47 4 2783 23 1 false 0.9662741250353215 0.9662741250353215 0.0 immunoglobulin_mediated_immune_response GO:0016064 12133 89 47 1 92 1 1 false 0.967391304347824 0.967391304347824 7.963051441312322E-6 cellular_component_morphogenesis GO:0032989 12133 810 47 2 5068 31 4 false 0.9691594266639674 0.9691594266639674 0.0 mitochondrial_part GO:0044429 12133 557 47 1 7185 43 3 false 0.9692042737153113 0.9692042737153113 0.0 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 47 3 199 3 1 false 0.9700015227652451 0.9700015227652451 5.075884472869322E-5 viral_reproduction GO:0016032 12133 633 47 19 634 19 1 false 0.9700315457414661 0.9700315457414661 0.0015772870662463625 transporter_activity GO:0005215 12133 746 47 1 10383 47 2 false 0.9701748791965191 0.9701748791965191 0.0 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 47 5 1007 5 2 false 0.970503501092729 0.970503501092729 7.008686204750717E-16 purine_ribonucleoside_binding GO:0032550 12133 1629 47 8 1635 8 2 false 0.9709550845429742 0.9709550845429742 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 47 8 1639 8 1 false 0.9710252105572678 0.9710252105572678 3.7483303336303164E-17 organophosphate_biosynthetic_process GO:0090407 12133 477 47 1 4948 35 2 false 0.9715864720137403 0.9715864720137403 0.0 myelination GO:0042552 12133 70 47 1 72 1 1 false 0.9722222222222209 0.9722222222222209 3.912363067292673E-4 regulation_of_intracellular_protein_transport GO:0033157 12133 160 47 1 847 17 3 false 0.972598993285585 0.972598993285585 1.5386851760422239E-177 nucleoside_binding GO:0001882 12133 1639 47 8 4455 35 3 false 0.9744006276068968 0.9744006276068968 0.0 cell_communication GO:0007154 12133 3962 47 14 7541 37 1 false 0.9752839746188643 0.9752839746188643 0.0 multicellular_organismal_process GO:0032501 12133 4223 47 13 10446 47 1 false 0.975860072172426 0.975860072172426 0.0 focal_adhesion GO:0005925 12133 122 47 1 125 1 1 false 0.9759999999999686 0.9759999999999686 3.1471282454758027E-6 integral_to_membrane GO:0016021 12133 2318 47 1 2375 1 1 false 0.9760000000014666 0.9760000000014666 3.0839384482043954E-116 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 47 6 7461 44 2 false 0.9762811393734149 0.9762811393734149 0.0 regulation_of_gene_expression GO:0010468 12133 2935 47 22 4361 41 2 false 0.9769743171644925 0.9769743171644925 0.0 protein_import_into_nucleus GO:0006606 12133 200 47 2 690 17 5 false 0.9776305317524713 0.9776305317524713 1.1794689955817937E-179 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 47 4 2528 17 3 false 0.9778619643857339 0.9778619643857339 0.0 regulation_of_cellular_catabolic_process GO:0031329 12133 494 47 1 5000 37 3 false 0.9790101634879168 0.9790101634879168 0.0 leukocyte_activation GO:0045321 12133 475 47 1 1729 12 2 false 0.9791206180106655 0.9791206180106655 0.0 cell_projection_organization GO:0030030 12133 744 47 1 7663 38 2 false 0.97957358273055 0.97957358273055 0.0 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 47 1 4947 35 2 false 0.9805707195972713 0.9805707195972713 0.0 chromosomal_part GO:0044427 12133 512 47 1 5337 39 2 false 0.9807081714892588 0.9807081714892588 0.0 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 47 1 5099 35 2 false 0.9815654630313025 0.9815654630313025 0.0 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 47 5 1085 5 1 false 0.9816686606152377 0.9816686606152377 1.7413918354446858E-11 ion_binding GO:0043167 12133 4448 47 15 8962 43 1 false 0.9824446328993041 0.9824446328993041 0.0 cytoskeletal_part GO:0044430 12133 1031 47 3 5573 40 2 false 0.9861957603224206 0.9861957603224206 0.0 catalytic_activity GO:0003824 12133 4901 47 15 10478 47 2 false 0.986817407813897 0.986817407813897 0.0 single-multicellular_organism_process GO:0044707 12133 4095 47 13 8057 38 2 false 0.987195592892172 0.987195592892172 0.0 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 47 35 7976 43 2 false 0.9873184756313086 0.9873184756313086 0.0 chordate_embryonic_development GO:0043009 12133 471 47 1 477 1 1 false 0.9874213836479633 0.9874213836479633 6.308586670641318E-14 regulation_of_transport GO:0051049 12133 942 47 3 3017 23 2 false 0.988631677774896 0.988631677774896 0.0 membrane-bounded_organelle GO:0043227 12133 7284 47 35 7980 43 1 false 0.9894899539064211 0.9894899539064211 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 47 4 1225 6 2 false 0.9898876664638337 0.9898876664638337 5.928244845001387E-155 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 47 18 4395 38 3 false 0.9902473986177915 0.9902473986177915 0.0 Golgi_apparatus GO:0005794 12133 828 47 1 8213 44 2 false 0.9908016021273827 0.9908016021273827 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 47 6 1319 6 1 false 0.9909194554665322 0.9909194554665322 1.1504554077729292E-6 lipid_metabolic_process GO:0006629 12133 769 47 1 7599 44 3 false 0.9909818915600326 0.9909818915600326 0.0 organophosphate_catabolic_process GO:0046434 12133 1000 47 5 2495 25 2 false 0.990999781191557 0.990999781191557 0.0 neuron_differentiation GO:0030182 12133 812 47 1 2154 10 2 false 0.9912992382748502 0.9912992382748502 0.0 translation_initiation_factor_activity GO:0003743 12133 50 47 1 191 15 2 false 0.9914353007504614 0.9914353007504614 3.1223441687767467E-47 ion_transmembrane_transporter_activity GO:0015075 12133 469 47 1 589 3 2 false 0.9917114322325029 0.9917114322325029 1.1842155919657181E-128 endoplasmic_reticulum GO:0005783 12133 854 47 1 8213 44 2 false 0.9921273633876799 0.9921273633876799 0.0 cell_periphery GO:0071944 12133 2667 47 6 9983 46 1 false 0.9923289783330055 0.9923289783330055 0.0 epithelium_migration GO:0090132 12133 130 47 1 131 1 1 false 0.9923664122137256 0.9923664122137256 0.007633587786259341 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 47 5 2517 25 2 false 0.9932707320488413 0.9932707320488413 0.0 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 47 6 672 19 1 false 0.9934037416236062 0.9934037416236062 6.935915883902889E-199 protein_modification_process GO:0036211 12133 2370 47 13 3518 28 2 false 0.9937024325682573 0.9937024325682573 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 47 10 7256 45 1 false 0.9940195397907013 0.9940195397907013 0.0 interphase GO:0051325 12133 233 47 1 253 2 1 false 0.9940397766482572 0.9940397766482572 4.555981744751407E-30 pyrophosphatase_activity GO:0016462 12133 1080 47 5 1081 5 1 false 0.995374653099011 0.995374653099011 9.250693802031629E-4 glycosyl_compound_catabolic_process GO:1901658 12133 956 47 5 2175 24 2 false 0.9953994185682944 0.9953994185682944 0.0 establishment_of_protein_localization_to_mitochondrion GO:0072655 12133 66 47 1 211 14 2 false 0.9957421061206475 0.9957421061206475 1.9619733177914497E-56 plasma_membrane GO:0005886 12133 2594 47 5 10252 46 3 false 0.9957932966234814 0.9957932966234814 0.0 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 47 5 2643 25 2 false 0.9958253624842139 0.9958253624842139 0.0 response_to_other_organism GO:0051707 12133 475 47 3 1194 20 2 false 0.9964050161726433 0.9964050161726433 0.0 chromosome GO:0005694 12133 592 47 1 3226 28 1 false 0.9966647419150872 0.9966647419150872 0.0 virus-host_interaction GO:0019048 12133 355 47 6 588 19 2 false 0.9976087756642151 0.9976087756642151 1.0104535019427035E-170 single-organism_metabolic_process GO:0044710 12133 2877 47 8 8027 45 1 false 0.9977160266707449 0.9977160266707449 0.0 plasma_membrane_part GO:0044459 12133 1329 47 1 10213 46 3 false 0.9983843957904367 0.9983843957904367 0.0 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 47 5 2849 30 1 false 0.9989965493463085 0.9989965493463085 0.0 protein_localization_to_nucleus GO:0034504 12133 233 47 2 516 16 1 false 0.9991794716276488 0.9991794716276488 1.4955266190313754E-153 protein_targeting_to_nucleus GO:0044744 12133 200 47 2 443 16 1 false 0.9991979385685249 0.9991979385685249 9.352491047681514E-132 cytoskeleton GO:0005856 12133 1430 47 5 3226 28 1 false 0.999266598748465 0.999266598748465 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 47 18 3611 34 3 false 0.9993046707466183 0.9993046707466183 0.0 macromolecular_complex_assembly GO:0065003 12133 973 47 5 1603 19 2 false 0.9995224272528996 0.9995224272528996 0.0 purine-containing_compound_catabolic_process GO:0072523 12133 959 47 5 1651 21 6 false 0.9997178820154156 0.9997178820154156 0.0 membrane GO:0016020 12133 4398 47 8 10701 46 1 false 0.9998531554891761 0.9998531554891761 0.0 cellular_protein_modification_process GO:0006464 12133 2370 47 13 3038 27 2 false 0.9998601415538761 0.9998601415538761 0.0 nucleoside_catabolic_process GO:0009164 12133 952 47 5 1516 20 5 false 0.9998939334834258 0.9998939334834258 0.0 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 47 5 1587 21 3 false 0.9999117314343535 0.9999117314343535 0.0 purine_nucleotide_binding GO:0017076 12133 1650 47 8 1997 18 1 false 0.9999625175093344 0.9999625175093344 0.0 ribonucleotide_binding GO:0032553 12133 1651 47 8 1997 18 1 false 0.9999635678257729 0.9999635678257729 0.0 protein_complex_assembly GO:0006461 12133 743 47 3 1214 18 3 false 0.9999857818861425 0.9999857818861425 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 47 17 3220 35 4 false 0.9999909240723904 0.9999909240723904 0.0 membrane_part GO:0044425 12133 2995 47 2 10701 46 2 false 0.9999949580098342 0.9999949580098342 0.0 DNA_binding GO:0003677 12133 2091 47 9 2849 30 1 false 0.9999998941119135 0.9999998941119135 0.0 protein_complex GO:0043234 12133 2976 47 14 3462 35 1 false 0.9999999999603778 0.9999999999603778 0.0 GO:0000000 12133 11221 47 47 0 0 0 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 47 2 307 2 1 true 1.0 1.0 1.0 axon_ensheathment GO:0008366 12133 72 47 1 72 1 1 true 1.0 1.0 1.0 cullin_deneddylation GO:0010388 12133 9 47 1 9 1 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 47 1 304 1 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 47 1 147 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 47 3 87 3 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 47 5 1169 5 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 47 6 417 6 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 47 3 124 3 2 true 1.0 1.0 1.0