ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min ribonucleoprotein_complex GO:0030529 12133 569 66 30 9264 66 2 false 1.4583127109282E-19 1.4583127109282E-19 0.0 multi-organism_cellular_process GO:0044764 12133 634 66 27 9702 65 2 false 8.198005717645723E-16 8.198005717645723E-16 0.0 macromolecular_complex GO:0032991 12133 3462 66 52 10701 66 1 false 9.976438503532844E-15 9.976438503532844E-15 0.0 mRNA_metabolic_process GO:0016071 12133 573 66 30 3294 46 1 false 5.136285670010331E-13 5.136285670010331E-13 0.0 translational_elongation GO:0006414 12133 121 66 15 3388 40 2 false 1.5574444374699893E-12 1.5574444374699893E-12 5.332026529203484E-226 cytosolic_part GO:0044445 12133 178 66 16 5117 49 2 false 2.886439221846452E-12 2.886439221846452E-12 0.0 translational_initiation GO:0006413 12133 160 66 14 7667 57 2 false 5.9459728990595486E-12 5.9459728990595486E-12 0.0 ribosomal_subunit GO:0044391 12133 132 66 14 7199 65 4 false 6.6710392219021046E-12 6.6710392219021046E-12 2.5906239763169356E-285 ribosome GO:0005840 12133 210 66 15 6755 61 3 false 2.965673476982317E-10 2.965673476982317E-10 0.0 reproduction GO:0000003 12133 1345 66 29 10446 66 1 false 4.2575672967855234E-10 4.2575672967855234E-10 0.0 viral_transcription GO:0019083 12133 145 66 14 2964 37 3 false 5.587776697314076E-10 5.587776697314076E-10 1.0927707330622845E-250 RNA_catabolic_process GO:0006401 12133 203 66 16 4368 52 3 false 6.211521740703873E-10 6.211521740703873E-10 0.0 multi-organism_process GO:0051704 12133 1180 66 27 10446 66 1 false 6.231161919092233E-10 6.231161919092233E-10 0.0 reproductive_process GO:0022414 12133 1275 66 28 10446 66 2 false 6.597700376516508E-10 6.597700376516508E-10 0.0 cellular_metabolic_process GO:0044237 12133 7256 66 65 10007 65 2 false 7.78339139341847E-10 7.78339139341847E-10 0.0 macromolecule_catabolic_process GO:0009057 12133 820 66 27 6846 64 2 false 9.298279148617533E-10 9.298279148617533E-10 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 66 25 6457 65 3 false 2.0196355879078194E-9 2.0196355879078194E-9 0.0 organelle_part GO:0044422 12133 5401 66 56 10701 66 2 false 4.845790031613435E-9 4.845790031613435E-9 0.0 translational_termination GO:0006415 12133 92 66 14 513 17 2 false 6.3626682765604086E-9 6.3626682765604086E-9 3.4634519853301643E-104 cellular_process_involved_in_reproduction GO:0048610 12133 469 66 17 9699 65 2 false 7.028400294856166E-9 7.028400294856166E-9 0.0 cytosol GO:0005829 12133 2226 66 41 5117 49 1 false 7.083692285104039E-9 7.083692285104039E-9 0.0 protein_complex_disassembly GO:0043241 12133 154 66 14 1031 21 2 false 7.258048238497006E-8 7.258048238497006E-8 4.7545827865276796E-188 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 66 64 7569 65 2 false 7.887259273940073E-8 7.887259273940073E-8 0.0 catabolic_process GO:0009056 12133 2164 66 38 8027 65 1 false 8.167998143816669E-8 8.167998143816669E-8 0.0 structural_molecule_activity GO:0005198 12133 526 66 16 10257 66 1 false 1.4345356939964934E-7 1.4345356939964934E-7 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 66 14 516 17 1 false 1.6074801095782863E-7 1.6074801095782863E-7 8.917305549619806E-119 cellular_component_disassembly GO:0022411 12133 351 66 14 7663 58 2 false 2.2339248518667966E-7 2.2339248518667966E-7 0.0 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 66 15 1239 23 2 false 2.399988634931423E-7 2.399988634931423E-7 4.427655683668096E-244 protein_targeting_to_ER GO:0045047 12133 104 66 14 721 24 3 false 4.230018700001548E-7 4.230018700001548E-7 1.514347826459292E-128 RNA_binding GO:0003723 12133 763 66 25 2849 38 1 false 4.690036991691049E-7 4.690036991691049E-7 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 66 37 7502 65 2 false 4.702963298593399E-7 4.702963298593399E-7 0.0 metabolic_process GO:0008152 12133 8027 66 65 10446 66 1 false 5.573172990640572E-7 5.573172990640572E-7 0.0 macromolecular_complex_disassembly GO:0032984 12133 199 66 14 1380 24 2 false 5.711691875664563E-7 5.711691875664563E-7 1.9082717261040364E-246 RNA_processing GO:0006396 12133 601 66 22 3762 47 2 false 5.856115779720345E-7 5.856115779720345E-7 0.0 single-organism_transport GO:0044765 12133 2323 66 34 8134 57 2 false 8.901581919201709E-7 8.901581919201709E-7 0.0 protein_targeting GO:0006605 12133 443 66 19 2378 34 2 false 1.1099957800123475E-6 1.1099957800123475E-6 0.0 cellular_catabolic_process GO:0044248 12133 1972 66 36 7289 65 2 false 1.2057185794835028E-6 1.2057185794835028E-6 0.0 structural_constituent_of_ribosome GO:0003735 12133 152 66 14 526 16 1 false 1.2223120829467579E-6 1.2223120829467579E-6 1.18011379183299E-136 multi-organism_reproductive_process GO:0044703 12133 707 66 27 1275 28 1 false 1.2914053489513406E-6 1.2914053489513406E-6 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 66 64 7451 64 1 false 1.5576227782502889E-6 1.5576227782502889E-6 0.0 cellular_localization GO:0051641 12133 1845 66 30 7707 56 2 false 1.5624694400758734E-6 1.5624694400758734E-6 0.0 establishment_of_localization GO:0051234 12133 2833 66 36 10446 66 2 false 2.168087149864185E-6 2.168087149864185E-6 0.0 protein_metabolic_process GO:0019538 12133 3431 66 48 7395 64 2 false 2.7986385702855955E-6 2.7986385702855955E-6 0.0 intracellular_organelle_part GO:0044446 12133 5320 66 56 9083 66 3 false 3.7735841197665757E-6 3.7735841197665757E-6 0.0 localization GO:0051179 12133 3467 66 40 10446 66 1 false 4.299542969219847E-6 4.299542969219847E-6 0.0 intracellular_transport GO:0046907 12133 1148 66 28 2815 36 2 false 6.107751794112233E-6 6.107751794112233E-6 0.0 organelle GO:0043226 12133 7980 66 63 10701 66 1 false 7.752576638897347E-6 7.752576638897347E-6 0.0 translation GO:0006412 12133 457 66 17 5433 63 3 false 1.0428288364371477E-5 1.0428288364371477E-5 0.0 cytosolic_ribosome GO:0022626 12133 92 66 14 296 17 2 false 1.0494227437012493E-5 1.0494227437012493E-5 4.2784789004852985E-79 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 66 27 5528 56 2 false 2.5873973781603063E-5 2.5873973781603063E-5 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 66 27 5462 57 2 false 3.632637105863186E-5 3.632637105863186E-5 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 66 27 5392 57 2 false 4.4226976853538726E-5 4.4226976853538726E-5 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 66 27 5388 57 2 false 4.909494227337756E-5 4.909494227337756E-5 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 66 27 4878 54 5 false 6.07174398579709E-5 6.07174398579709E-5 0.0 intracellular_protein_transport GO:0006886 12133 658 66 22 1672 29 3 false 6.226741182898829E-5 6.226741182898829E-5 0.0 viral_reproductive_process GO:0022415 12133 557 66 27 783 27 2 false 8.420125238122684E-5 8.420125238122684E-5 1.4346997744229993E-203 cellular_macromolecule_localization GO:0070727 12133 918 66 23 2206 30 2 false 9.289420240044959E-5 9.289420240044959E-5 0.0 cellular_protein_metabolic_process GO:0044267 12133 3038 66 48 5899 64 2 false 9.33652607087955E-5 9.33652607087955E-5 0.0 Prp19_complex GO:0000974 12133 78 66 6 2976 30 1 false 9.606942246920134E-5 9.606942246920134E-5 3.570519754703887E-156 regulation_of_signaling GO:0023051 12133 1793 66 24 6715 45 2 false 1.2874851710078546E-4 1.2874851710078546E-4 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 66 33 10701 66 1 false 1.2879417654817473E-4 1.2879417654817473E-4 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 66 14 220 15 2 false 1.7289017598000821E-4 1.7289017598000821E-4 1.3850176335002185E-65 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 66 39 10446 66 1 false 1.7803810023672007E-4 1.7803810023672007E-4 0.0 protein_targeting_to_membrane GO:0006612 12133 145 66 14 443 19 1 false 2.2635345909788736E-4 2.2635345909788736E-4 5.648405296311656E-121 intracellular_receptor_signaling_pathway GO:0030522 12133 217 66 8 3547 29 1 false 2.4147415247782614E-4 2.4147415247782614E-4 0.0 regulation_of_cell_communication GO:0010646 12133 1796 66 24 6469 45 2 false 2.479036057813903E-4 2.479036057813903E-4 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 66 5 3151 36 3 false 2.576578157642901E-4 2.576578157642901E-4 1.4828410310444421E-114 spliceosomal_complex GO:0005681 12133 150 66 9 3020 45 2 false 2.755642246030363E-4 2.755642246030363E-4 2.455159410572961E-258 apoptotic_signaling_pathway GO:0097190 12133 305 66 9 3954 30 2 false 2.8786265513380767E-4 2.8786265513380767E-4 0.0 macromolecular_complex_subunit_organization GO:0043933 12133 1256 66 24 3745 39 1 false 2.9558852466156116E-4 2.9558852466156116E-4 0.0 nucleus GO:0005634 12133 4764 66 47 7259 54 1 false 3.3124802152470007E-4 3.3124802152470007E-4 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 66 54 7341 63 5 false 3.3953329881204893E-4 3.3953329881204893E-4 0.0 innate_immune_response GO:0045087 12133 626 66 14 1268 15 2 false 3.8738815126390387E-4 3.8738815126390387E-4 0.0 I-kappaB/NF-kappaB_complex GO:0033256 12133 5 66 2 9248 66 2 false 4.947495579335431E-4 4.947495579335431E-4 1.775872679278938E-18 neurotrophin_signaling_pathway GO:0038179 12133 253 66 9 2018 21 2 false 4.978788529329933E-4 4.978788529329933E-4 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 66 44 8962 63 1 false 5.118433667712517E-4 5.118433667712517E-4 0.0 regulation_of_response_to_stimulus GO:0048583 12133 2074 66 24 7292 46 2 false 5.696284132472643E-4 5.696284132472643E-4 0.0 ubiquitin_ligase_complex GO:0000151 12133 147 66 6 9248 66 2 false 6.036983654350551E-4 6.036983654350551E-4 0.0 organic_cyclic_compound_binding GO:0097159 12133 4407 66 44 8962 63 1 false 6.890889078777051E-4 6.890889078777051E-4 0.0 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 66 4 1977 23 3 false 8.751839578014193E-4 8.751839578014193E-4 8.49513097758148E-83 nucleic_acid_metabolic_process GO:0090304 12133 3799 66 48 6846 64 2 false 9.54609237143957E-4 9.54609237143957E-4 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 66 16 5778 38 3 false 9.660107172328384E-4 9.660107172328384E-4 0.0 regulation_of_signal_transduction GO:0009966 12133 1603 66 22 3826 31 4 false 9.71394525303656E-4 9.71394525303656E-4 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 66 38 7980 63 1 false 0.0010811497860023652 0.0010811497860023652 0.0 nucleic_acid_binding GO:0003676 12133 2849 66 38 4407 44 2 false 0.0011311427214538104 0.0011311427214538104 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 66 38 7958 63 2 false 0.0011496684974821767 0.0011496684974821767 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 66 54 8027 65 1 false 0.0012092695099938807 0.0012092695099938807 0.0 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 66 16 174 16 1 false 0.0012147749679994263 0.0012147749679994263 2.5039480990851377E-47 cellular_protein_localization GO:0034613 12133 914 66 23 1438 25 2 false 0.0012704595596489802 0.0012704595596489802 0.0 negative_regulation_of_dephosphorylation GO:0035305 12133 6 66 2 562 6 3 false 0.0014002709419340179 0.0014002709419340179 2.3471675405869638E-14 receptor_signaling_protein_activity GO:0005057 12133 339 66 7 1070 8 1 false 0.0017849690871875154 0.0017849690871875154 2.5248591221043436E-289 intracellular_part GO:0044424 12133 9083 66 66 9983 66 2 false 0.0019169693329938833 0.0019169693329938833 0.0 regulation_of_transferase_activity GO:0051338 12133 667 66 11 2708 19 2 false 0.0019383109491190366 0.0019383109491190366 0.0 cytoplasmic_part GO:0044444 12133 5117 66 49 9083 66 2 false 0.0019567896600849195 0.0019567896600849195 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 66 7 2025 21 2 false 0.0020022648867756214 0.0020022648867756214 5.184659787643375E-271 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 66 54 7451 64 1 false 0.0020395302550831594 0.0020395302550831594 0.0 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 66 6 3020 45 2 false 0.002240743224257516 0.002240743224257516 1.1070924240418437E-179 positive_regulation_of_signaling GO:0023056 12133 817 66 13 4861 34 3 false 0.0022587232911989137 0.0022587232911989137 0.0 establishment_of_localization_in_cell GO:0051649 12133 1633 66 29 2978 37 2 false 0.0024710975616341257 0.0024710975616341257 0.0 positive_regulation_of_cell_communication GO:0010647 12133 820 66 13 4819 34 3 false 0.0025321129001142366 0.0025321129001142366 0.0 molecular_function GO:0003674 12133 10257 66 66 11221 66 1 false 0.002614724027200984 0.002614724027200984 0.0 establishment_of_protein_localization GO:0045184 12133 1153 66 23 3010 37 2 false 0.0026515081107044572 0.0026515081107044572 0.0 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 66 8 201 16 3 false 0.002720172505097281 0.002720172505097281 2.854176062301069E-41 immune_response-regulating_signaling_pathway GO:0002764 12133 310 66 8 3626 30 2 false 0.002863746341744036 0.002863746341744036 0.0 GABA_receptor_binding GO:0050811 12133 8 66 2 918 10 1 false 0.002890474823861316 0.002890474823861316 8.242553036140362E-20 positive_regulation_of_molecular_function GO:0044093 12133 1303 66 17 10257 66 2 false 0.002954201618480961 0.002954201618480961 0.0 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 66 8 2035 18 3 false 0.002992218907326903 0.002992218907326903 0.0 response_to_growth_factor_stimulus GO:0070848 12133 545 66 12 1783 19 1 false 0.003205565041256669 0.003205565041256669 0.0 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 66 21 4597 36 2 false 0.003294411635771856 0.003294411635771856 0.0 receptor_tyrosine_kinase_binding GO:0030971 12133 31 66 3 918 10 1 false 0.003568814192113 0.003568814192113 1.9469822979582718E-58 intracellular GO:0005622 12133 9171 66 66 9983 66 1 false 0.0036305385341250294 0.0036305385341250294 0.0 autophagic_vacuole GO:0005776 12133 32 66 3 310 4 1 false 0.0037489470461219425 0.0037489470461219425 2.6078243370159197E-44 regulation_of_protein_metabolic_process GO:0051246 12133 1388 66 23 5563 55 3 false 0.0043240796939031535 0.0043240796939031535 0.0 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 66 9 3842 31 3 false 0.004499488529595469 0.004499488529595469 0.0 phosphoprotein_binding GO:0051219 12133 42 66 3 6397 52 1 false 0.004651902373677089 0.004651902373677089 2.265958128878875E-109 heterocycle_metabolic_process GO:0046483 12133 4933 66 54 7256 65 1 false 0.004652041204310119 0.004652041204310119 0.0 negative_regulation_of_RNA_splicing GO:0033119 12133 15 66 3 1037 25 3 false 0.004657291089784378 0.004657291089784378 8.39457188486895E-34 ligase_activity GO:0016874 12133 504 66 9 4901 33 1 false 0.004827896803956784 0.004827896803956784 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 66 54 7256 65 1 false 0.00487290188591986 0.00487290188591986 0.0 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 66 3 243 6 2 false 0.005034453582328388 0.005034453582328388 1.7559807727942103E-26 viral_genome_expression GO:0019080 12133 153 66 14 557 27 2 false 0.005121292643127755 0.005121292643127755 1.6461772406083414E-141 positive_regulation_of_signal_transduction GO:0009967 12133 782 66 13 3650 30 5 false 0.005618325140781668 0.005618325140781668 0.0 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 66 8 835 14 2 false 0.006026347611526083 0.006026347611526083 8.0742416973675315E-196 negative_regulation_of_metabolic_process GO:0009892 12133 1354 66 19 8327 65 3 false 0.006096129588347755 0.006096129588347755 0.0 negative_regulation_of_biological_process GO:0048519 12133 2732 66 27 10446 66 2 false 0.006211455225101758 0.006211455225101758 0.0 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 66 14 145 14 1 false 0.006314654865156731 0.006314654865156731 1.7288474062512548E-37 mRNA_catabolic_process GO:0006402 12133 181 66 16 592 30 2 false 0.006449174103068702 0.006449174103068702 1.4563864024176219E-157 RNA_helicase_activity GO:0003724 12133 27 66 3 140 3 1 false 0.006535144555163191 0.006535144555163191 1.8047202528374888E-29 Peyer's_patch_morphogenesis GO:0061146 12133 1 66 1 2812 19 3 false 0.006756756756760372 0.006756756756760372 3.5561877667107997E-4 SH2_domain_binding GO:0042169 12133 31 66 3 486 7 1 false 0.006929058950546908 0.006929058950546908 1.1318841086292139E-49 protein_kinase_CK2_complex GO:0005956 12133 1 66 1 9248 66 2 false 0.007136678200692098 0.007136678200692098 1.081314878885772E-4 heat_shock_protein_binding GO:0031072 12133 49 66 3 6397 52 1 false 0.007173850039023573 0.007173850039023573 2.351284918255247E-124 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 66 2 856 13 3 false 0.007224143498430884 0.007224143498430884 1.5339974177634096E-21 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 66 8 650 13 2 false 0.007321170158937562 0.007321170158937562 6.010278185218431E-162 macromolecule_localization GO:0033036 12133 1642 66 27 3467 40 1 false 0.007818907752116296 0.007818907752116296 0.0 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 66 6 1130 13 2 false 0.00796442749393662 0.00796442749393662 2.620015602340521E-209 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 66 3 201 3 3 false 0.007995199879996553 0.007995199879996553 9.949481941404742E-44 nuclear_part GO:0044428 12133 2767 66 35 6936 63 2 false 0.00829709331031665 0.00829709331031665 0.0 IkappaB_kinase_complex GO:0008385 12133 10 66 2 3063 44 2 false 0.00843639709687181 0.00843639709687181 5.066173975414688E-29 cellular_response_to_progesterone_stimulus GO:0071393 12133 1 66 1 117 1 3 false 0.008547008547008409 0.008547008547008409 0.008547008547008409 positive_regulation_of_cyclic-nucleotide_phosphodiesterase_activity GO:0051343 12133 1 66 1 578 5 3 false 0.008650519031144657 0.008650519031144657 0.001730103806228656 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 66 11 3702 30 3 false 0.00865317442812208 0.00865317442812208 0.0 positive_regulation_of_biological_process GO:0048518 12133 3081 66 29 10446 66 2 false 0.008728066425536963 0.008728066425536963 0.0 biological_process GO:0008150 12133 10446 66 66 11221 66 1 false 0.008758586549340147 0.008758586549340147 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 66 15 1779 15 1 false 0.009271011026454548 0.009271011026454548 0.0 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 66 9 587 11 2 false 0.009416532803162368 0.009416532803162368 2.854325455984618E-173 positive_regulation_of_ion_transmembrane_transporter_activity GO:0032414 12133 28 66 2 473 3 3 false 0.009784888342737223 0.009784888342737223 8.750359231366189E-46 immune_system_process GO:0002376 12133 1618 66 18 10446 66 1 false 0.00979177206126614 0.00979177206126614 0.0 RNA_splicing GO:0008380 12133 307 66 17 601 22 1 false 0.00989355672410738 0.00989355672410738 4.262015823312228E-180 signal_transduction_by_phosphorylation GO:0023014 12133 307 66 7 3947 32 2 false 0.009922138273176596 0.009922138273176596 0.0 cell_part GO:0044464 12133 9983 66 66 10701 66 2 false 0.010067809085588023 0.010067809085588023 0.0 cell GO:0005623 12133 9984 66 66 10701 66 1 false 0.0101348060001807 0.0101348060001807 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 66 21 5303 55 3 false 0.010241584743898902 0.010241584743898902 0.0 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 66 10 742 11 2 false 0.010412762365245784 0.010412762365245784 9.121396596563632E-222 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 66 54 7275 65 2 false 0.01046182265739368 0.01046182265739368 0.0 positive_regulation_of_cellular_process GO:0048522 12133 2811 66 28 9694 65 3 false 0.010560277155926178 0.010560277155926178 0.0 cellular_membrane_organization GO:0016044 12133 784 66 12 7541 56 2 false 0.011065185922558568 0.011065185922558568 0.0 mRNA_splice_site_selection GO:0006376 12133 18 66 3 117 4 2 false 0.011309325094537932 0.011309325094537932 1.505085052005422E-21 positive_regulation_of_metabolic_process GO:0009893 12133 1872 66 23 8366 65 3 false 0.011310474822760336 0.011310474822760336 0.0 immune_response GO:0006955 12133 1006 66 14 5335 40 2 false 0.011496630028933218 0.011496630028933218 0.0 enzyme_binding GO:0019899 12133 1005 66 15 6397 52 1 false 0.011607248610885112 0.011607248610885112 0.0 N-terminal_myristoylation_domain_binding GO:0031997 12133 1 66 1 85 1 1 false 0.011764705882353043 0.011764705882353043 0.011764705882353043 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 66 13 5051 34 3 false 0.01181218464195935 0.01181218464195935 0.0 activation_of_MAPKK_activity GO:0000186 12133 64 66 4 496 8 3 false 0.011862600927267628 0.011862600927267628 2.7437381948522894E-82 posterior_midgut_development GO:0007497 12133 2 66 1 3099 19 2 false 0.012226397611364351 0.012226397611364351 2.0831810007242536E-7 mRNA_3'-splice_site_recognition GO:0000389 12133 5 66 3 18 3 1 false 0.01225490196078434 0.01225490196078434 1.1671335200746984E-4 regulation_of_innate_immune_response GO:0045088 12133 226 66 8 868 14 3 false 0.012649521709746108 0.012649521709746108 2.196344369914344E-215 small_molecule_binding GO:0036094 12133 2102 66 23 8962 63 1 false 0.013282859440927854 0.013282859440927854 0.0 sperm_entry GO:0035037 12133 1 66 1 2708 36 4 false 0.013293943870018025 0.013293943870018025 3.692762186116122E-4 protein_transport GO:0015031 12133 1099 66 23 1627 26 2 false 0.01342736570518338 0.01342736570518338 0.0 regulation_of_molecular_function GO:0065009 12133 2079 66 21 10494 66 2 false 0.013968995681447669 0.013968995681447669 0.0 regulation_of_immune_response GO:0050776 12133 533 66 11 2461 26 3 false 0.014011477718880496 0.014011477718880496 0.0 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 66 14 1975 21 1 false 0.014017563557913976 0.014017563557913976 0.0 Cul5-RING_ubiquitin_ligase_complex GO:0031466 12133 5 66 2 90 4 1 false 0.014306176840078386 0.014306176840078386 2.2753507521444733E-8 maturation_of_SSU-rRNA GO:0030490 12133 8 66 2 104 3 2 false 0.015068312612572342 0.015068312612572342 3.8823564737710265E-12 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 66 7 856 11 3 false 0.015596631755858561 0.015596631755858561 2.175375701359491E-221 positive_regulation_of_cation_channel_activity GO:2001259 12133 17 66 2 224 3 3 false 0.015599840711947892 0.015599840711947892 7.366387194248368E-26 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 66 18 7606 65 4 false 0.015632262117596073 0.015632262117596073 0.0 intracellular_signal_transduction GO:0035556 12133 1813 66 21 3547 29 1 false 0.0159876779695759 0.0159876779695759 0.0 regulation_of_protein_dephosphorylation GO:0035304 12133 14 66 2 1152 17 3 false 0.016814450032436038 0.016814450032436038 1.3017113495112525E-32 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 66 5 1881 22 2 false 0.017220285834546326 0.017220285834546326 3.367676499542027E-210 cellular_response_to_organic_substance GO:0071310 12133 1347 66 19 1979 21 2 false 0.017253654260501114 0.017253654260501114 0.0 regulation_of_mRNA_processing GO:0050684 12133 49 66 3 3175 36 3 false 0.01725693362126815 0.01725693362126815 2.292701139367024E-109 regulation_of_immune_system_process GO:0002682 12133 794 66 11 6789 47 2 false 0.017401297025916924 0.017401297025916924 0.0 cellular_response_to_cold GO:0070417 12133 2 66 1 1140 10 2 false 0.017474546770793936 0.017474546770793936 1.540286185173837E-6 negative_regulation_of_cellular_process GO:0048523 12133 2515 66 25 9689 65 3 false 0.017848190326814554 0.017848190326814554 0.0 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 66 3 1642 22 2 false 0.018212578596744987 0.018212578596744987 5.767987369966462E-86 negative_regulation_of_molecular_function GO:0044092 12133 735 66 10 10257 66 2 false 0.018322140486630896 0.018322140486630896 0.0 RNA_metabolic_process GO:0016070 12133 3294 66 46 5627 64 2 false 0.01859740678962421 0.01859740678962421 0.0 regulation_of_cyclic-nucleotide_phosphodiesterase_activity GO:0051342 12133 2 66 1 836 8 2 false 0.019058533650411526 0.019058533650411526 2.8650832306672945E-6 viral_infectious_cycle GO:0019058 12133 213 66 16 557 27 1 false 0.01908249403640063 0.01908249403640063 3.455075709157513E-160 positive_regulation_of_immune_system_process GO:0002684 12133 540 66 10 3595 33 3 false 0.01916210400189145 0.01916210400189145 0.0 replication_fork_protection_complex GO:0031298 12133 2 66 1 3062 30 3 false 0.019502213963833066 0.019502213963833066 2.133838170991397E-7 positive_regulation_of_transferase_activity GO:0051347 12133 445 66 8 2275 19 3 false 0.02002854433946754 0.02002854433946754 0.0 organ_maturation GO:0048799 12133 3 66 1 1934 13 2 false 0.02004051126352603 0.02004051126352603 8.30722176927825E-10 negative_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060266 12133 3 66 1 738 5 8 false 0.020215039954932623 0.020215039954932623 1.4988203684165303E-8 regulation_of_cell_communication_by_electrical_coupling_involved_in_cardiac_conduction GO:1901844 12133 2 66 1 2510 26 4 false 0.020613917387430826 0.020613917387430826 3.1758180510276897E-7 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 66 39 5597 54 2 false 0.021430102531649543 0.021430102531649543 0.0 activation_of_immune_response GO:0002253 12133 341 66 8 1618 18 2 false 0.021472370466940144 0.021472370466940144 0.0 defense_response GO:0006952 12133 1018 66 15 2540 24 1 false 0.02157290556859231 0.02157290556859231 0.0 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 66 11 2776 26 3 false 0.022280972294888596 0.022280972294888596 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 66 39 5588 54 2 false 0.022564505536802303 0.022564505536802303 0.0 cell_cycle GO:0007049 12133 1295 66 16 7541 56 1 false 0.023080805769914493 0.023080805769914493 0.0 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 66 17 4044 50 3 false 0.02309050734043747 0.02309050734043747 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway_involved_in_phagocytosis GO:0002433 12133 72 66 3 500 5 2 false 0.023131128171620267 0.023131128171620267 6.2427882790248544E-89 interferon-gamma_receptor_binding GO:0005133 12133 2 66 1 172 2 1 false 0.02318781449748341 0.02318781449748341 6.799945600435015E-5 positive_regulation_of_protein_modification_process GO:0031401 12133 708 66 14 2417 29 3 false 0.023192443813309066 0.023192443813309066 0.0 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 66 39 5686 54 2 false 0.023281907647093637 0.023281907647093637 0.0 positive_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060265 12133 2 66 1 589 7 7 false 0.0236478292505407 0.0236478292505407 5.774805677789514E-6 cell_motility GO:0048870 12133 785 66 8 1249 8 3 false 0.024025528509763226 0.024025528509763226 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 66 39 5629 54 2 false 0.02508712870565935 0.02508712870565935 0.0 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 66 13 1730 22 2 false 0.025301230431588273 0.025301230431588273 0.0 binding GO:0005488 12133 8962 66 63 10257 66 1 false 0.025829178923863196 0.025829178923863196 0.0 NF-kappaB_binding GO:0051059 12133 21 66 2 715 9 1 false 0.02613724960460843 0.02613724960460843 7.883315092172008E-41 autophagic_vacuole_membrane GO:0000421 12133 15 66 2 149 3 2 false 0.02688450675027829 0.02688450675027829 6.842145126024584E-21 filtration_diaphragm GO:0036056 12133 6 66 1 222 1 1 false 0.02702702702702625 0.02702702702702625 6.438789470640111E-12 MAP_kinase_kinase_activity GO:0004708 12133 74 66 4 521 9 3 false 0.02704958295557875 0.02704958295557875 6.903948166738437E-92 activation_of_MAPK_activity GO:0000187 12133 158 66 6 286 6 2 false 0.027224135057754856 0.027224135057754856 8.207976102051858E-85 intracellular_organelle GO:0043229 12133 7958 66 63 9096 66 2 false 0.02735540009352437 0.02735540009352437 0.0 biosynthetic_process GO:0009058 12133 4179 66 42 8027 65 1 false 0.027387697037077007 0.027387697037077007 0.0 gene_expression GO:0010467 12133 3708 66 47 6052 64 1 false 0.02790565302785814 0.02790565302785814 0.0 negative_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043154 12133 63 66 3 1373 15 3 false 0.02822740330634976 0.02822740330634976 1.783777218833555E-110 beta-tubulin_binding GO:0048487 12133 26 66 2 150 2 1 false 0.029082774049217185 0.029082774049217185 1.0631424532785207E-29 positive_regulation_of_integrin_activation GO:0033625 12133 3 66 1 103 1 3 false 0.029126213592232487 0.029126213592232487 5.654477498006604E-6 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 66 6 859 13 3 false 0.029147316681986155 0.029147316681986155 4.662302019201105E-186 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 66 12 1356 19 2 false 0.029195425181968222 0.029195425181968222 0.0 negative_regulation_of_nucleocytoplasmic_transport GO:0046823 12133 54 66 3 343 5 3 false 0.029327548083761562 0.029327548083761562 2.3530708460848664E-64 cysteine-type_endopeptidase_activity GO:0004197 12133 219 66 4 527 4 2 false 0.029344529034444275 0.029344529034444275 1.229090165658057E-154 protein_binding GO:0005515 12133 6397 66 52 8962 63 1 false 0.029635594325563546 0.029635594325563546 0.0 platelet_activation GO:0030168 12133 203 66 4 863 6 2 false 0.029850512182719988 0.029850512182719988 1.0918730712206789E-203 regulation_of_cell_junction_assembly GO:1901888 12133 35 66 2 1245 10 3 false 0.02999814310776507 0.02999814310776507 7.812749785355693E-69 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 66 6 1525 16 1 false 0.03020969312640689 0.03020969312640689 1.2095302863090285E-289 embryonic_cleavage GO:0040016 12133 5 66 1 1138 7 2 false 0.030432539408481684 0.030432539408481684 6.342949764440575E-14 cytoplasmic_vesicle_membrane GO:0030659 12133 302 66 4 719 4 3 false 0.03076666118967767 0.03076666118967767 1.2351303462379864E-211 negative_regulation_of_mRNA_processing GO:0050686 12133 13 66 2 1096 24 3 false 0.030950595175686005 0.030950595175686005 2.031276795679201E-30 neuron_cell-cell_adhesion GO:0007158 12133 9 66 1 284 1 1 false 0.03169014084507238 0.03169014084507238 3.431681294200574E-17 endocytic_vesicle GO:0030139 12133 152 66 3 712 4 1 false 0.03227555847690703 0.03227555847690703 1.2528026489004738E-159 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 66 4 1014 14 1 false 0.03240856032470541 0.03240856032470541 2.468210871514413E-134 negative_regulation_of_protein_homooligomerization GO:0032463 12133 6 66 1 184 1 3 false 0.03260869565217537 0.03260869565217537 2.0145965447507594E-11 glomerulus_development GO:0032835 12133 48 66 2 3152 19 3 false 0.03293503288240106 0.03293503288240106 2.079589057162791E-107 protein_catabolic_process GO:0030163 12133 498 66 12 3569 49 2 false 0.03308329288691636 0.03308329288691636 0.0 intracellular_protein_kinase_cascade GO:0007243 12133 806 66 14 1813 21 1 false 0.033098578214965 0.033098578214965 0.0 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 66 12 374 15 2 false 0.03322557475945664 0.03322557475945664 2.0954491420584897E-111 negative_regulation_of_cysteine-type_endopeptidase_activity GO:2000117 12133 66 66 3 303 4 3 false 0.033593178683768 0.033593178683768 1.924144504065005E-68 phosphatase_activator_activity GO:0019211 12133 7 66 1 616 3 3 false 0.03375921766325402 0.03375921766325402 1.5496135150275104E-16 DNA_catabolic_process,_exonucleolytic GO:0000738 12133 9 66 1 257 1 2 false 0.03501945525291883 0.03501945525291883 8.548342373692236E-17 regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060334 12133 22 66 2 114 2 3 false 0.035863996273872246 0.035863996273872246 5.496543393824805E-24 calcium-dependent_protein_binding GO:0048306 12133 37 66 2 6397 52 1 false 0.036013810801578054 0.036013810801578054 2.3062856812384995E-98 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 66 16 5183 42 2 false 0.03618803193604572 0.03618803193604572 0.0 positive_regulation_of_immune_response GO:0050778 12133 394 66 9 1600 20 4 false 0.036442128805327476 0.036442128805327476 0.0 positive_regulation_of_transporter_activity GO:0032411 12133 34 66 2 2101 19 4 false 0.03660146114238025 0.03660146114238025 4.2098203958278254E-75 regulation_of_epithelial_cell_migration GO:0010632 12133 90 66 3 1654 14 3 false 0.03665041989574499 0.03665041989574499 3.756993278892793E-151 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 66 2 3208 24 2 false 0.03683669167890674 0.03683669167890674 7.591030632914061E-95 negative_regulation_of_sodium_ion_transport GO:0010766 12133 5 66 1 135 1 3 false 0.03703703703703773 0.03703703703703773 2.884335739945468E-9 ephrin_receptor_binding GO:0046875 12133 29 66 2 918 10 1 false 0.03707022836398003 0.03707022836398003 1.6526990639165767E-55 negative_regulation_of_peptidase_activity GO:0010466 12133 156 66 3 695 4 3 false 0.03717212134242 0.03717212134242 5.1885244604442586E-160 protein_C-terminus_binding GO:0008022 12133 157 66 4 6397 52 1 false 0.038022712723782846 0.038022712723782846 2.34014E-319 smooth_endoplasmic_reticulum GO:0005790 12133 11 66 1 854 3 1 false 0.03819027206887999 0.03819027206887999 2.416597178942871E-25 microtubule_cytoskeleton GO:0015630 12133 734 66 9 1430 11 1 false 0.03910325624596098 0.03910325624596098 0.0 cellular_process GO:0009987 12133 9675 66 65 10446 66 1 false 0.039276105945669555 0.039276105945669555 0.0 unfolded_protein_binding GO:0051082 12133 93 66 3 6397 52 1 false 0.039401134781078095 0.039401134781078095 2.507796527596117E-210 pre-mRNA_binding GO:0036002 12133 10 66 2 763 25 1 false 0.039497863494917004 0.039497863494917004 5.757557985229243E-23 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 66 6 599 11 2 false 0.04003395938356652 0.04003395938356652 1.7219296535416308E-148 energy_derivation_by_oxidation_of_organic_compounds GO:0015980 12133 271 66 3 788 3 2 false 0.04037958388111394 0.04037958388111394 1.8657076333624725E-219 positive_regulation_of_metanephros_development GO:0072216 12133 3 66 1 74 1 3 false 0.04054054054054041 0.04054054054054041 1.5426385289399006E-5 negative_regulation_of_respiratory_burst GO:0060268 12133 3 66 1 1370 19 3 false 0.04106106007377606 0.04106106007377606 2.3385202648234984E-9 regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033146 12133 20 66 3 56 3 2 false 0.04112554112554134 0.04112554112554134 1.2728904491493287E-15 organic_substance_transport GO:0071702 12133 1580 66 26 2783 36 1 false 0.041157364550947664 0.041157364550947664 0.0 regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060264 12133 4 66 1 1701 18 6 false 0.041697099050312804 0.041697099050312804 2.8769144126071423E-12 regulation_of_metabolic_process GO:0019222 12133 4469 66 39 9189 65 2 false 0.04295439839437727 0.04295439839437727 0.0 response_to_redox_state GO:0051775 12133 6 66 1 5200 38 1 false 0.043073215659514934 0.043073215659514934 3.652293320951714E-20 cellular_component GO:0005575 12133 10701 66 66 11221 66 1 false 0.04323889070208863 0.04323889070208863 0.0 RNA-dependent_ATPase_activity GO:0008186 12133 21 66 2 228 4 1 false 0.043395866376402914 0.043395866376402914 4.020483440001667E-30 single-organism_process GO:0044699 12133 8052 66 57 10446 66 1 false 0.043554287680543244 0.043554287680543244 0.0 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 66 16 3771 50 4 false 0.043705616565871866 0.043705616565871866 0.0 positive_regulation_of_angiogenesis GO:0045766 12133 71 66 2 774 4 3 false 0.044097889303112585 0.044097889303112585 1.852564870808831E-102 SNARE_binding GO:0000149 12133 42 66 2 6397 52 1 false 0.0453820339439011 0.0453820339439011 2.265958128878875E-109 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 66 37 8688 65 3 false 0.04561843963266608 0.04561843963266608 0.0 positive_regulation_of_circadian_rhythm GO:0042753 12133 5 66 1 3105 29 3 false 0.04586366753208624 0.04586366753208624 4.1713112204170434E-16 DNA_topological_change GO:0006265 12133 9 66 1 194 1 1 false 0.04639175257732184 0.04639175257732184 1.1254898761359862E-15 regulation_of_protein_kinase_activity GO:0045859 12133 621 66 11 1169 14 3 false 0.046674420969565325 0.046674420969565325 0.0 cytoplasmic_transport GO:0016482 12133 666 66 21 1148 28 1 false 0.04676364238442966 0.04676364238442966 0.0 organic_substance_metabolic_process GO:0071704 12133 7451 66 64 8027 65 1 false 0.047022718496129406 0.047022718496129406 0.0 nuclear_body GO:0016604 12133 272 66 5 805 7 1 false 0.04720967407052695 0.04720967407052695 8.12188174084084E-223 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 66 2 1199 12 2 false 0.047896334314409726 0.047896334314409726 9.194442294553035E-70 glomerular_epithelial_cell_development GO:0072310 12133 8 66 1 167 1 2 false 0.04790419161676506 0.04790419161676506 7.90168466842574E-14 clathrin-sculpted_glutamate_transport_vesicle_membrane GO:0060203 12133 3 66 1 124 2 3 false 0.04799370574350717 0.04799370574350717 3.2245166449548196E-6 regulation_of_cation_channel_activity GO:2001257 12133 33 66 2 244 3 2 false 0.04886754613529337 0.04886754613529337 1.3783310605710322E-41 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 66 21 3547 29 1 false 0.049033495676883164 0.049033495676883164 0.0 regulation_of_kinase_activity GO:0043549 12133 654 66 11 1335 15 3 false 0.049562402900163095 0.049562402900163095 0.0 regulation_of_transmembrane_transporter_activity GO:0022898 12133 78 66 2 563 3 3 false 0.05180276569455496 0.05180276569455496 8.813007984613145E-98 cellular_sodium_ion_homeostasis GO:0006883 12133 5 66 1 283 3 3 false 0.05225438592501784 0.05225438592501784 6.84978827344915E-11 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 66 7 750 10 3 false 0.05259606871844705 0.05259606871844705 3.090255244762607E-218 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 66 12 2370 28 1 false 0.05300086730018912 0.05300086730018912 0.0 clathrin-sculpted_glutamate_transport_vesicle GO:0060199 12133 3 66 1 112 2 2 false 0.053088803088802324 0.053088803088802324 4.387504387504258E-6 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 66 1 6481 59 2 false 0.053413211193865086 0.053413211193865086 9.738359623180132E-21 response_to_stress GO:0006950 12133 2540 66 24 5200 38 1 false 0.053471272601537695 0.053471272601537695 0.0 tissue_migration GO:0090130 12133 131 66 3 4095 27 1 false 0.05349419417310506 0.05349419417310506 4.3202440607580954E-251 primary_metabolic_process GO:0044238 12133 7288 66 63 8027 65 1 false 0.053729626793989654 0.053729626793989654 0.0 type_I_interferon_production GO:0032606 12133 71 66 3 362 5 1 false 0.05373302340837874 0.05373302340837874 2.8677775679244762E-77 mitochondrial_DNA_replication GO:0006264 12133 5 66 1 93 1 2 false 0.05376344086021428 0.05376344086021428 1.9241395291318295E-8 zymogen_granule GO:0042588 12133 11 66 1 202 1 1 false 0.054455445544553525 0.054455445544553525 2.304850985097709E-18 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 66 4 217 8 1 false 0.05536892226565209 0.05536892226565209 4.514459380304185E-47 extrinsic_apoptotic_signaling_pathway GO:0097191 12133 77 66 3 2096 24 2 false 0.05542585759721558 0.05542585759721558 1.0680041317028193E-142 regulation_of_viral_genome_replication GO:0045069 12133 43 66 2 181 2 3 false 0.055432780847142024 0.055432780847142024 1.1493804978494703E-42 response_to_osmotic_stress GO:0006970 12133 43 66 2 2681 24 2 false 0.05549897842402794 0.05549897842402794 3.246680302266631E-95 ubiquitin_conjugating_enzyme_complex GO:0031371 12133 8 66 1 9248 66 2 false 0.05570806129412606 0.05570806129412606 7.5588062911204355E-28 adiponectin-mediated_signaling_pathway GO:0033211 12133 3 66 1 318 6 1 false 0.055714736690629145 0.055714736690629145 1.8835527421137004E-7 maintenance_of_DNA_methylation GO:0010216 12133 5 66 1 791 9 2 false 0.0557479933179108 0.0557479933179108 3.9246390269706394E-13 DNA_topoisomerase_activity GO:0003916 12133 8 66 1 2199 16 2 false 0.056835540075745414 0.056835540075745414 7.468869718379493E-23 positive_regulation_of_podosome_assembly GO:0071803 12133 6 66 1 104 1 4 false 0.05769230769230619 0.05769230769230619 6.590300114226586E-10 morphogenesis_of_an_endothelium GO:0003159 12133 7 66 1 352 3 2 false 0.058644133644143386 0.058644133644143386 7.992864813964357E-15 prostate_gland_growth GO:0060736 12133 10 66 1 498 3 3 false 0.05915594617061803 0.05915594617061803 4.236088489692508E-21 regulation_of_histone_ubiquitination GO:0033182 12133 4 66 1 265 4 3 false 0.05935341153100818 0.05935341153100818 4.978567515771174E-9 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 66 3 1679 15 3 false 0.05950276380443448 0.05950276380443448 1.5952227787322578E-167 positive_regulation_of_respiratory_burst GO:0060267 12133 5 66 1 1885 23 3 false 0.05959894912492133 0.05959894912492133 5.069092992061398E-15 ion_channel_binding GO:0044325 12133 49 66 2 6397 52 1 false 0.059811361235411725 0.059811361235411725 2.351284918255247E-124 regulation_of_ion_transmembrane_transporter_activity GO:0032412 12133 73 66 2 485 3 3 false 0.060589408554015886 0.060589408554015886 1.1784649326580688E-88 water_homeostasis GO:0030104 12133 14 66 1 677 3 1 false 0.060852428385694865 0.060852428385694865 2.3492827505763342E-29 death GO:0016265 12133 1528 66 16 8052 57 1 false 0.061032096919123216 0.061032096919123216 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 66 42 7470 64 2 false 0.06121248139101445 0.06121248139101445 0.0 regulation_of_type_I_interferon_production GO:0032479 12133 67 66 3 325 5 2 false 0.06129146488586309 0.06129146488586309 2.788484219003069E-71 ribonucleoprotein_complex_assembly GO:0022618 12133 117 66 4 646 9 3 false 0.06142364605199731 0.06142364605199731 4.631331466925404E-132 enteric_nervous_system_development GO:0048484 12133 10 66 1 2686 17 2 false 0.061619010529764436 0.061619010529764436 1.8879370584191156E-28 single-organism_cellular_process GO:0044763 12133 7541 66 56 9888 66 2 false 0.06192653665459137 0.06192653665459137 0.0 positive_regulation_of_phosphoprotein_phosphatase_activity GO:0032516 12133 7 66 1 222 2 4 false 0.062207003383467255 0.062207003383467255 2.0866447358555543E-13 inositol_phosphate_metabolic_process GO:0043647 12133 44 66 2 2783 26 3 false 0.06247670094893208 0.06247670094893208 1.0337589650636944E-97 positive_regulation_of_response_to_DNA_damage_stimulus GO:2001022 12133 44 66 2 3212 30 4 false 0.06262518554955167 0.06262518554955167 1.7987290458431554E-100 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 66 21 7638 65 4 false 0.06299243000984531 0.06299243000984531 0.0 phosphoserine_binding GO:0050815 12133 4 66 1 125 2 2 false 0.06322580645161026 0.06322580645161026 1.0318453263855228E-7 cysteine-type_peptidase_activity GO:0008234 12133 295 66 4 586 4 1 false 0.06357478998987709 0.06357478998987709 1.2148857586981575E-175 regulation_of_cellular_component_movement GO:0051270 12133 412 66 6 6475 45 3 false 0.06365539832582062 0.06365539832582062 0.0 nucleoside_metabolic_process GO:0009116 12133 1083 66 10 2072 13 4 false 0.06367078571174181 0.06367078571174181 0.0 positive_regulation_of_defense_response GO:0031349 12133 229 66 6 1621 21 3 false 0.06391159908950107 0.06391159908950107 6.85443065618377E-286 negative_regulation_of_tyrosine_phosphorylation_of_STAT_protein GO:0042532 12133 5 66 1 78 1 4 false 0.0641025641025628 0.0641025641025628 4.736846842109758E-8 regulation_of_skeletal_muscle_cell_differentiation GO:2001014 12133 27 66 2 105 2 3 false 0.06428571428571116 0.06428571428571116 1.1402717682449654E-25 protein_localization_to_organelle GO:0033365 12133 516 66 17 914 23 1 false 0.06480833804859214 0.06480833804859214 5.634955900168089E-271 pseudopodium GO:0031143 12133 13 66 1 976 5 1 false 0.06497743558501831 0.06497743558501831 9.253153669613935E-30 regulation_of_cell_communication_by_electrical_coupling GO:0010649 12133 5 66 1 1800 24 2 false 0.06498275212793359 0.06498275212793359 6.386067148425523E-15 endocytic_vesicle_membrane GO:0030666 12133 97 66 3 352 4 2 false 0.0652992979640645 0.0652992979640645 2.1109282121886535E-89 regulation_of_cell_death GO:0010941 12133 1062 66 12 6437 46 2 false 0.06532116360711585 0.06532116360711585 0.0 cytoplasmic_mRNA_processing_body GO:0000932 12133 44 66 2 5117 49 2 false 0.06588476364659779 0.06588476364659779 2.0344134807470182E-109 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 66 8 912 12 2 false 0.0660075741084472 0.0660075741084472 2.059888800891414E-267 mitochondrial_DNA_metabolic_process GO:0032042 12133 6 66 1 796 9 2 false 0.06615249732138331 0.06615249732138331 2.8844096855332024E-15 positive_regulation_of_sodium_ion_transport GO:0010765 12133 11 66 1 166 1 3 false 0.06626506024096748 0.06626506024096748 2.123209741249517E-17 rhythmic_process GO:0048511 12133 148 66 3 10446 66 1 false 0.06686511438361614 0.06686511438361614 0.0 regulation_of_podosome_assembly GO:0071801 12133 7 66 1 202 2 3 false 0.06827249889167446 0.06827249889167446 4.0795527185171627E-13 regulation_of_metanephric_glomerulus_development GO:0072298 12133 5 66 1 73 1 4 false 0.06849315068493189 0.06849315068493189 6.657641567757416E-8 clathrin_coat_of_coated_pit GO:0030132 12133 14 66 1 1370 7 3 false 0.06952457680234837 0.06952457680234837 1.135698186932346E-33 MAP_kinase_kinase_kinase_activity GO:0004709 12133 26 66 2 520 9 3 false 0.06973152925794662 0.06973152925794662 1.8429565665115438E-44 sodium_channel_inhibitor_activity GO:0019871 12133 3 66 1 43 1 3 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 prostaglandin-E_synthase_activity GO:0050220 12133 3 66 1 43 1 1 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 regulation_of_localization GO:0032879 12133 1242 66 14 7621 57 2 false 0.07001660448393902 0.07001660448393902 0.0 homeostasis_of_number_of_cells GO:0048872 12133 166 66 4 990 10 1 false 0.07005410230470689 0.07005410230470689 1.128853988781411E-193 rRNA_metabolic_process GO:0016072 12133 107 66 3 258 3 1 false 0.07015944541217921 0.07015944541217921 1.860360860420455E-75 regulation_of_biological_quality GO:0065008 12133 2082 66 19 6908 46 1 false 0.07022275528586283 0.07022275528586283 0.0 negative_regulation_of_protein_dephosphorylation GO:0035308 12133 4 66 1 444 8 4 false 0.07037923304022037 0.07037923304022037 6.259846539070891E-10 ureter_development GO:0072189 12133 11 66 1 2877 19 3 false 0.07041168009510741 0.07041168009510741 3.640238366547604E-31 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 66 2 1385 14 2 false 0.07047355378629244 0.07047355378629244 3.166663017097352E-84 uterus_development GO:0060065 12133 11 66 1 2873 19 3 false 0.07050665250107131 0.07050665250107131 3.6964769721782132E-31 ameboidal_cell_migration GO:0001667 12133 185 66 4 734 7 1 false 0.07150361699324519 0.07150361699324519 3.1688746703355204E-179 regulation_of_integrin_activation GO:0033623 12133 7 66 1 190 2 2 false 0.07251461988303691 0.07251461988303691 6.305407803350028E-13 regulation_of_catalytic_activity GO:0050790 12133 1692 66 16 6953 46 3 false 0.07257234207477675 0.07257234207477675 0.0 DNA_double-strand_break_processing GO:0000729 12133 8 66 1 110 1 2 false 0.07272727272727175 0.07272727272727175 2.4407768686605466E-12 actin_filament GO:0005884 12133 48 66 2 3318 31 3 false 0.07307203103199329 0.07307203103199329 1.7385873776725597E-108 protein_polyubiquitination GO:0000209 12133 163 66 6 548 11 1 false 0.07331157892795817 0.07331157892795817 3.681189236491621E-144 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 66 16 2780 26 2 false 0.07349281590967452 0.07349281590967452 0.0 regulation_of_phosphorylation GO:0042325 12133 845 66 13 1820 20 2 false 0.07358717863513814 0.07358717863513814 0.0 regulation_of_protein_homooligomerization GO:0032462 12133 14 66 1 189 1 2 false 0.07407407407407184 0.07407407407407184 1.9240310274561344E-21 nucleus_organization GO:0006997 12133 62 66 2 2031 15 1 false 0.07460845739953265 0.07460845739953265 6.73570952581451E-120 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 66 9 504 9 1 false 0.07507767824287245 0.07507767824287245 6.011520399617331E-122 pigment_granule GO:0048770 12133 87 66 2 712 4 1 false 0.07515232378481648 0.07515232378481648 3.4546414966613156E-114 GTPase_inhibitor_activity GO:0005095 12133 13 66 1 836 5 3 false 0.07554573002908307 0.07554573002908307 7.01976356108195E-29 regulation_of_respiratory_burst GO:0060263 12133 9 66 1 4476 39 2 false 0.07580542205653851 0.07580542205653851 5.072797550268562E-28 protein_dephosphorylation GO:0006470 12133 146 66 4 2505 28 2 false 0.07626982858223566 0.07626982858223566 5.1980515318736674E-241 regulation_of_dephosphorylation GO:0035303 12133 87 66 3 1455 17 2 false 0.0764305834209328 0.0764305834209328 1.9687002630039133E-142 regulation_of_DNA_binding GO:0051101 12133 67 66 2 2162 15 2 false 0.07663951450617504 0.07663951450617504 3.7616659824415835E-129 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 66 3 987 10 2 false 0.07690944911391816 0.07690944911391816 9.48284116235963E-143 lymphocyte_migration_into_lymphoid_organs GO:0097021 12133 2 66 1 26 1 1 false 0.07692307692307682 0.07692307692307682 0.003076923076923083 protein_phosphatase_activator_activity GO:0072542 12133 4 66 1 52 1 2 false 0.07692307692307719 0.07692307692307719 3.6937852063902836E-6 BRCA1-A_complex GO:0070531 12133 7 66 1 4399 50 2 false 0.07695205373721882 0.07695205373721882 1.5886457483779712E-22 male_sex_determination GO:0030238 12133 13 66 1 3069 19 2 false 0.07770593478543966 0.07770593478543966 2.9810795844016348E-36 clathrin_coat_of_trans-Golgi_network_vesicle GO:0030130 12133 11 66 1 414 3 3 false 0.07779417080526002 0.07779417080526002 7.453188898335812E-22 mucosal-associated_lymphoid_tissue_development GO:0048537 12133 10 66 1 491 4 1 false 0.07924630470992496 0.07924630470992496 4.886639260320744E-21 clathrin-sculpted_monoamine_transport_vesicle_membrane GO:0070083 12133 5 66 1 124 2 3 false 0.07933385785470452 0.07933385785470452 4.441482982031481E-9 signal_transduction GO:0007165 12133 3547 66 29 6702 45 4 false 0.07942192111750834 0.07942192111750834 0.0 nuclear_lumen GO:0031981 12133 2490 66 32 3186 36 2 false 0.07946598028907711 0.07946598028907711 0.0 skeletal_muscle_acetylcholine-gated_channel_clustering GO:0071340 12133 4 66 1 50 1 3 false 0.07999999999999938 0.07999999999999938 4.342162396873629E-6 nephron_development GO:0072006 12133 79 66 2 3152 19 3 false 0.08057763178514575 0.08057763178514575 9.804100439545243E-160 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 66 7 309 8 2 false 0.08073828066666866 0.08073828066666866 7.558729588417702E-91 protein_kinase_activity GO:0004672 12133 1014 66 14 1347 15 3 false 0.08253405289141207 0.08253405289141207 0.0 polyol_metabolic_process GO:0019751 12133 63 66 2 218 2 1 false 0.08256880733943553 0.08256880733943553 2.003050842244071E-56 macromolecule_biosynthetic_process GO:0009059 12133 3475 66 40 6537 64 2 false 0.08332251350859168 0.08332251350859168 0.0 BRCA1-BARD1_complex GO:0031436 12133 2 66 1 24 1 1 false 0.08333333333333307 0.08333333333333307 0.0036231884057970967 positive_regulation_of_activin_receptor_signaling_pathway GO:0032927 12133 6 66 1 72 1 3 false 0.08333333333333329 0.08333333333333329 6.400454360574509E-9 regulation_of_ligase_activity GO:0051340 12133 98 66 3 2061 22 2 false 0.08339500711009913 0.08339500711009913 1.6310105681359867E-170 endothelial_tube_morphogenesis GO:0061154 12133 7 66 1 245 3 2 false 0.08362101367565489 0.08362101367565489 1.0371147261725795E-13 cytokine_production GO:0001816 12133 362 66 5 4095 27 1 false 0.08410299530194952 0.08410299530194952 0.0 positive_regulation_of_kidney_development GO:0090184 12133 10 66 1 917 8 4 false 0.08429286444350234 0.08429286444350234 9.066837179798457E-24 DNA_topoisomerase_type_II_(ATP-hydrolyzing)_activity GO:0003918 12133 6 66 1 71 1 2 false 0.08450704225352183 0.08450704225352183 6.9823138478995105E-9 rRNA_processing GO:0006364 12133 102 66 3 231 3 3 false 0.08467325346002468 0.08467325346002468 2.6685808966337758E-68 icosanoid_metabolic_process GO:0006690 12133 52 66 1 614 1 2 false 0.08469055374594564 0.08469055374594564 7.712236630953538E-77 regulation_of_defense_response GO:0031347 12133 387 66 8 1253 16 2 false 0.08509987799502688 0.08509987799502688 0.0 cell_death GO:0008219 12133 1525 66 16 7542 56 2 false 0.08526585994896968 0.08526585994896968 0.0 negative_regulation_of_mRNA_3'-end_processing GO:0031441 12133 2 66 1 92 4 3 false 0.08552317247969338 0.08552317247969338 2.3889154323936682E-4 response_to_chemical_stimulus GO:0042221 12133 2369 66 22 5200 38 1 false 0.08572277764893997 0.08572277764893997 0.0 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 66 1 3020 45 2 false 0.08620769955851816 0.08620769955851816 9.537822615543818E-19 signal_transduction_in_absence_of_ligand GO:0038034 12133 11 66 1 3547 29 1 false 0.08646436948019849 0.08646436948019849 3.6259640720530813E-32 regulation_of_blood_vessel_endothelial_cell_migration GO:0043535 12133 36 66 3 80 3 2 false 0.08690360272638521 0.08690360272638521 1.3816777818746476E-23 cell_communication_by_electrical_coupling GO:0010644 12133 12 66 1 3962 30 1 false 0.08728928247969799 0.08728928247969799 3.2554041064980747E-35 clathrin-sculpted_monoamine_transport_vesicle GO:0070081 12133 5 66 1 112 2 2 false 0.08767696267696147 0.08767696267696147 7.454135894502656E-9 response_to_endogenous_stimulus GO:0009719 12133 982 66 11 5200 38 1 false 0.08787963758080894 0.08787963758080894 0.0 mitotic_nuclear_envelope_reassembly GO:0007084 12133 8 66 1 1043 12 3 false 0.08870602963054057 0.08870602963054057 2.957556257561267E-20 cell_cycle_process GO:0022402 12133 953 66 11 7541 56 2 false 0.08872468842872792 0.08872468842872792 0.0 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 66 13 5447 55 3 false 0.09032759086335088 0.09032759086335088 0.0 response_to_cytokine_stimulus GO:0034097 12133 461 66 8 1783 19 1 false 0.09040654482405514 0.09040654482405514 0.0 cellular_protein_catabolic_process GO:0044257 12133 409 66 10 3174 49 3 false 0.0906957362797568 0.0906957362797568 0.0 regulation_of_MAP_kinase_activity GO:0043405 12133 268 66 7 533 9 3 false 0.09076886464627995 0.09076886464627995 1.0382438249699724E-159 midgut_development GO:0007494 12133 8 66 1 88 1 1 false 0.09090909090908832 0.09090909090908832 1.5557684929357358E-11 RNA_biosynthetic_process GO:0032774 12133 2751 66 37 4191 49 3 false 0.09242442207536658 0.09242442207536658 0.0 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 66 4 53 4 2 false 0.09358832066934064 0.09358832066934064 1.6040955778771873E-15 positive_regulation_of_innate_immune_response GO:0045089 12133 178 66 6 740 14 4 false 0.09369144586659994 0.09369144586659994 1.4450011889246649E-176 negative_regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060336 12133 4 66 1 83 2 4 false 0.09462239200705054 0.09462239200705054 5.441821486487924E-7 titin_binding GO:0031432 12133 11 66 1 556 5 1 false 0.09541364023943265 0.09541364023943265 2.809097474179898E-23 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 66 2 86 2 2 false 0.09603283173734763 0.09603283173734763 6.233113581740502E-23 positive_regulation_of_phosphorylation GO:0042327 12133 563 66 10 1487 18 3 false 0.09616707503948636 0.09616707503948636 0.0 podosome_assembly GO:0071800 12133 11 66 1 878 8 2 false 0.09630907941234751 0.09630907941234751 1.7784038056438803E-25 protein_domain_specific_binding GO:0019904 12133 486 66 7 6397 52 1 false 0.09641349846492342 0.09641349846492342 0.0 positive_regulation_of_ligase_activity GO:0051351 12133 84 66 3 1424 19 3 false 0.09689739286226834 0.09689739286226834 5.130084211911676E-138 cellular_biosynthetic_process GO:0044249 12133 4077 66 42 7290 65 2 false 0.09741901298787736 0.09741901298787736 0.0 signal_complex_assembly GO:0007172 12133 8 66 1 1808 23 2 false 0.0975327521414524 0.0975327521414524 3.5864785118030747E-22 negative_regulation_of_macrophage_derived_foam_cell_differentiation GO:0010745 12133 10 66 1 395 4 3 false 0.0978429321396656 0.0978429321396656 4.4022037255229464E-20 negative_regulation_of_protein_oligomerization GO:0032460 12133 7 66 1 343 5 3 false 0.09851262677317632 0.09851262677317632 9.596894376022029E-15 negative_regulation_of_transport GO:0051051 12133 243 66 5 4618 47 3 false 0.09872422632051914 0.09872422632051914 0.0 negative_regulation_of_catalytic_activity GO:0043086 12133 588 66 7 4970 34 3 false 0.09892315531613795 0.09892315531613795 0.0 membrane_organization GO:0061024 12133 787 66 12 3745 39 1 false 0.09924636959996608 0.09924636959996608 0.0 negative_regulation_of_endopeptidase_activity GO:0010951 12133 152 66 3 474 4 3 false 0.09925814950013288 0.09925814950013288 1.8080345918982332E-128 telomerase_holoenzyme_complex GO:0005697 12133 7 66 1 3020 45 2 false 0.09985091572297108 0.09985091572297108 2.2151545557067955E-21 negative_regulation_of_response_to_interferon-gamma GO:0060331 12133 4 66 1 117 3 3 false 0.09992695959712435 0.09992695959712435 1.348853238697819E-7 positive_regulation_of_kinase_activity GO:0033674 12133 438 66 8 1181 14 3 false 0.10114949575181045 0.10114949575181045 0.0 transcription_factor_import_into_nucleus GO:0042991 12133 64 66 2 200 2 1 false 0.10130653266330894 0.10130653266330894 5.887023324562289E-54 protein_complex_binding GO:0032403 12133 306 66 5 6397 52 1 false 0.10133963330889734 0.10133963330889734 0.0 signaling GO:0023052 12133 3878 66 30 10446 66 1 false 0.10170053860432404 0.10170053860432404 0.0 neurotrophin_receptor_binding GO:0005165 12133 9 66 1 172 2 1 false 0.10220318237453835 0.10220318237453835 3.4075419916065225E-15 renal_filtration_cell_differentiation GO:0061318 12133 14 66 1 2196 17 2 false 0.10338182839508649 0.10338182839508649 1.4982675159565203E-36 positive_regulation_of_extrinsic_apoptotic_signaling_pathway_in_absence_of_ligand GO:2001241 12133 3 66 1 29 1 3 false 0.1034482758620689 0.1034482758620689 2.7367268746579103E-4 NEDD8_ligase_activity GO:0019788 12133 4 66 1 335 9 1 false 0.10365561445528555 0.10365561445528555 1.9401604650455913E-9 phosphorylation GO:0016310 12133 1421 66 17 2776 26 1 false 0.10366921358691199 0.10366921358691199 0.0 negative_regulation_of_JAK-STAT_cascade GO:0046426 12133 8 66 1 223 3 3 false 0.10426050098959579 0.10426050098959579 7.485721025490751E-15 regulation_of_protein_modification_process GO:0031399 12133 1001 66 16 2566 31 2 false 0.10445136964495992 0.10445136964495992 0.0 positive_regulation_of_cell_migration_involved_in_sprouting_angiogenesis GO:0090050 12133 5 66 1 93 2 4 false 0.10518934081346172 0.10518934081346172 1.9241395291318295E-8 Fc-gamma_receptor_signaling_pathway_involved_in_phagocytosis GO:0038096 12133 72 66 3 151 3 4 false 0.10603137917240933 0.10603137917240933 6.349846956956757E-45 paraspeckles GO:0042382 12133 6 66 1 272 5 1 false 0.10628418301342021 0.10628418301342021 1.8794561691225117E-12 positive_regulation_of_organelle_assembly GO:1902117 12133 12 66 1 649 6 3 false 0.10632782501640374 0.10632782501640374 9.502313168071326E-26 negative_regulation_of_NF-kappaB_import_into_nucleus GO:0042347 12133 17 66 2 51 2 3 false 0.10666666666666579 0.10666666666666579 6.76999067656327E-14 intracellular_estrogen_receptor_signaling_pathway GO:0030520 12133 34 66 3 102 4 1 false 0.10666666666666605 0.10666666666666605 7.615480469304384E-28 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 66 8 1112 14 4 false 0.1070965367432535 0.1070965367432535 1.302733E-318 synaptobrevin_2-SNAP-25-syntaxin-1a_complex GO:0070044 12133 3 66 1 28 1 1 false 0.10714285714285729 0.10714285714285729 3.052503052503051E-4 regulation_of_potassium_ion_transmembrane_transport GO:1901379 12133 12 66 1 216 2 3 false 0.10826873385011943 0.10826873385011943 6.338882729411382E-20 clathrin-sculpted_vesicle GO:0060198 12133 9 66 1 162 2 1 false 0.10835058661144625 0.10835058661144625 5.920675767894615E-15 mitochondrial_genome_maintenance GO:0000002 12133 12 66 1 215 2 1 false 0.10875896544228764 0.10875896544228764 6.711758184082603E-20 negative_regulation_of_interleukin-2_production GO:0032703 12133 8 66 1 143 2 3 false 0.1091303063133948 0.1091303063133948 2.8144635666603867E-13 nuclear_replication_fork GO:0043596 12133 28 66 1 256 1 3 false 0.10937499999999821 0.10937499999999821 5.235583786811974E-38 positive_regulation_of_phosphatase_activity GO:0010922 12133 16 66 1 839 6 3 false 0.10941448614895398 0.10941448614895398 4.008024101855588E-34 glutamate_secretion GO:0014047 12133 24 66 1 633 3 4 false 0.10965276271780788 0.10965276271780788 5.63332818189107E-44 production_of_molecular_mediator_involved_in_inflammatory_response GO:0002532 12133 18 66 1 4184 27 2 false 0.1102114015065182 0.1102114015065182 4.3012458861645E-50 transport_vesicle GO:0030133 12133 108 66 2 712 4 1 false 0.11121465444515873 0.11121465444515873 5.898553548536589E-131 CMG_complex GO:0071162 12133 28 66 1 251 1 4 false 0.11155378486055467 0.11155378486055467 9.388589672695531E-38 ruffle GO:0001726 12133 119 66 2 990 5 2 false 0.11234994671368409 0.11234994671368409 2.995179002772035E-157 signal_sequence_binding GO:0005048 12133 20 66 1 178 1 1 false 0.11235955056180288 0.11235955056180288 7.23132468780732E-27 positive_regulation_of_cellular_component_movement GO:0051272 12133 216 66 4 3234 28 3 false 0.11264477485638168 0.11264477485638168 0.0 small_conjugating_protein_binding GO:0032182 12133 71 66 2 6397 52 1 false 0.11308420770426444 0.11308420770426444 7.493300865579233E-169 calmodulin_binding GO:0005516 12133 145 66 3 6397 52 1 false 0.11314975462685609 0.11314975462685609 5.666124490309724E-300 negative_regulation_of_cell_junction_assembly GO:1901889 12133 9 66 1 454 6 3 false 0.11379875406277264 0.11379875406277264 4.796392891885268E-19 negative_regulation_of_protein_complex_assembly GO:0031333 12133 63 66 2 954 9 3 false 0.11446586659309617 0.11446586659309617 3.124938390294621E-100 regulation_of_potassium_ion_transmembrane_transporter_activity GO:1901016 12133 9 66 1 153 2 3 false 0.11455108359131388 0.11455108359131388 1.0038611131963863E-14 Notch_signaling_pathway GO:0007219 12133 113 66 3 1975 21 1 false 0.11458983726738702 0.11458983726738702 2.33429872590278E-187 cytoplasm GO:0005737 12133 6938 66 55 9083 66 1 false 0.11473715790598618 0.11473715790598618 0.0 GINS_complex GO:0000811 12133 28 66 1 244 1 2 false 0.1147540983606434 0.1147540983606434 2.171851500338737E-37 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 66 3 202 12 1 false 0.11526564549176421 0.11526564549176421 5.801734415928739E-29 respiratory_burst_involved_in_defense_response GO:0002679 12133 9 66 1 1100 15 3 false 0.11664360965577356 0.11664360965577356 1.590299388551981E-22 copper_ion_binding GO:0005507 12133 36 66 1 1457 5 1 false 0.11773925162319877 0.11773925162319877 7.504507501554246E-73 negative_regulation_of_NF-kappaB_transcription_factor_activity GO:0032088 12133 51 66 3 103 3 1 false 0.11775449389598729 0.11775449389598729 1.2633713261943138E-30 regulation_of_peptide_secretion GO:0002791 12133 133 66 2 385 2 3 false 0.11874999999999115 0.11874999999999115 3.9095885277458606E-107 response_to_muramyl_dipeptide GO:0032495 12133 10 66 1 322 4 1 false 0.11908584031806788 0.11908584031806788 3.4874136507196575E-19 negative_regulation_of_protein_import_into_nucleus GO:0042308 12133 46 66 2 212 3 4 false 0.1194351119684135 0.1194351119684135 1.0466208389531854E-47 negative_regulation_of_cell-matrix_adhesion GO:0001953 12133 17 66 1 142 1 3 false 0.11971830985915556 0.11971830985915556 2.484430929274803E-22 cellular_response_to_stimulus GO:0051716 12133 4236 66 35 7871 56 2 false 0.11993285285520561 0.11993285285520561 0.0 Leydig_cell_differentiation GO:0033327 12133 10 66 1 2446 31 4 false 0.11995679462234192 0.11995679462234192 4.821684083574537E-28 cytokine-mediated_signaling_pathway GO:0019221 12133 318 66 6 2013 22 2 false 0.12004272986906891 0.12004272986906891 0.0 transcription_factor_binding GO:0008134 12133 715 66 9 6397 52 1 false 0.12031054717366771 0.12031054717366771 0.0 negative_regulation_of_lipid_storage GO:0010888 12133 13 66 1 2747 27 3 false 0.120754010574784 0.120754010574784 1.263188358714261E-35 response_to_corticosterone_stimulus GO:0051412 12133 16 66 1 257 2 4 false 0.12086575875485739 0.12086575875485739 9.304160154844702E-26 negative_regulation_of_tyrosine_phosphorylation_of_Stat3_protein GO:0042518 12133 4 66 1 33 1 3 false 0.12121212121212037 0.12121212121212037 2.4437927663734027E-5 leukocyte_homeostasis GO:0001776 12133 55 66 2 1628 18 2 false 0.12148534797955957 0.12148534797955957 7.300149261907148E-104 negative_regulation_of_ion_transmembrane_transporter_activity GO:0032413 12133 20 66 1 474 3 3 false 0.12156221409895245 0.12156221409895245 1.1144988320643829E-35 epithelial_cell_differentiation_involved_in_kidney_development GO:0035850 12133 31 66 1 491 2 3 false 0.122407415104536 0.122407415104536 8.158001597817135E-50 translation_initiation_factor_binding GO:0031369 12133 16 66 1 6397 52 1 false 0.1225597832327763 0.1225597832327763 2.711136666436817E-48 integrin_activation GO:0033622 12133 12 66 1 743 8 1 false 0.12268006076427039 0.12268006076427039 1.850332428419763E-26 cation_channel_activity GO:0005261 12133 216 66 3 433 3 2 false 0.1232699077820164 0.1232699077820164 1.1777872542675005E-129 respiratory_burst GO:0045730 12133 21 66 1 2877 18 1 false 0.12388800918851946 0.12388800918851946 1.2658513282149024E-53 positive_regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033148 12133 8 66 2 35 3 3 false 0.12406417112299364 0.12406417112299364 4.248842827655879E-8 MAP_kinase_activity GO:0004707 12133 277 66 7 520 9 2 false 0.12429126584504806 0.12429126584504806 2.5282679507054518E-155 negative_regulation_of_cell-substrate_adhesion GO:0010812 12133 29 66 1 231 1 3 false 0.12554112554112543 0.12554112554112543 1.5797205063531615E-37 regulation_of_locomotion GO:0040012 12133 398 66 5 6714 45 2 false 0.12554473834162364 0.12554473834162364 0.0 response_to_stimulus GO:0050896 12133 5200 66 38 10446 66 1 false 0.12556475683953178 0.12556475683953178 0.0 fibroblast_growth_factor_binding GO:0017134 12133 17 66 1 135 1 1 false 0.12592592592592816 0.12592592592592816 6.193063943061966E-22 protein_neddylation GO:0045116 12133 7 66 1 578 11 1 false 0.1264694650057949 0.1264694650057949 2.4253477298996185E-16 phospholipase_binding GO:0043274 12133 9 66 1 1005 15 1 false 0.12705850402638189 0.12705850402638189 3.596411174936099E-22 telomeric_DNA_binding GO:0042162 12133 16 66 1 1189 10 1 false 0.12715693708371506 0.12715693708371506 1.4512187070438412E-36 ATPase_activity GO:0016887 12133 307 66 5 1069 10 2 false 0.1281164294439227 0.1281164294439227 1.5605649392254874E-277 exon-exon_junction_complex GO:0035145 12133 12 66 1 4399 50 2 false 0.1283336030697396 0.1283336030697396 9.260000367357379E-36 protein_phosphatase_type_2A_complex GO:0000159 12133 19 66 1 9083 66 2 false 0.12951272503067068 0.12951272503067068 7.7076041303239345E-59 14-3-3_protein_binding GO:0071889 12133 17 66 1 6397 52 1 false 0.12971021283241033 0.12971021283241033 7.222899753868919E-51 skeletal_muscle_cell_differentiation GO:0035914 12133 57 66 2 251 3 2 false 0.13013353813661946 0.13013353813661946 6.638453930425573E-58 regulation_of_cell_differentiation GO:0045595 12133 872 66 9 6612 45 3 false 0.13017882466859493 0.13017882466859493 0.0 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 66 10 2556 17 1 false 0.1308241099759982 0.1308241099759982 0.0 regulation_of_response_to_interferon-gamma GO:0060330 12133 23 66 2 319 9 3 false 0.13135587338203877 0.13135587338203877 1.507111625705858E-35 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 66 6 417 8 4 false 0.1314422438272641 0.1314422438272641 8.022991700655629E-125 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 66 13 5032 55 4 false 0.1315853350723188 0.1315853350723188 0.0 negative_regulation_of_Notch_signaling_pathway GO:0045746 12133 13 66 1 646 7 3 false 0.13322490847963409 0.13322490847963409 2.0608061601230117E-27 positive_regulation_of_cell_adhesion_mediated_by_integrin GO:0033630 12133 18 66 1 135 1 3 false 0.1333333333333354 0.1333333333333354 9.447046692806282E-23 taxis GO:0042330 12133 488 66 5 1496 9 2 false 0.13344101790396248 0.13344101790396248 0.0 estrogen_receptor_binding GO:0030331 12133 23 66 2 62 2 1 false 0.13379164463247292 0.13379164463247292 1.6756493074771417E-17 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 66 39 4989 54 5 false 0.13439140681667894 0.13439140681667894 0.0 helicase_activity GO:0004386 12133 140 66 3 1059 10 1 false 0.1349554537057021 0.1349554537057021 6.632628106941949E-179 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 66 10 982 11 1 false 0.13592152171183255 0.13592152171183255 2.6984349291053464E-253 icosanoid_biosynthetic_process GO:0046456 12133 31 66 1 226 1 3 false 0.13716814159292384 0.13716814159292384 7.488265257194256E-39 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 66 14 6622 45 1 false 0.13744523267458736 0.13744523267458736 0.0 negative_regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010771 12133 20 66 1 822 6 4 false 0.13778261684181586 0.13778261684181586 1.5483743712673206E-40 single-stranded_RNA_binding GO:0003727 12133 40 66 3 763 25 1 false 0.13799537378555404 0.13799537378555404 1.1547828689277465E-67 muscle_cell_differentiation GO:0042692 12133 267 66 4 2218 17 2 false 0.13867359019605294 0.13867359019605294 0.0 peptide_secretion GO:0002790 12133 157 66 2 668 3 2 false 0.13932214989769323 0.13932214989769323 1.7691212755864333E-157 phospholipid_catabolic_process GO:0009395 12133 17 66 1 1245 11 3 false 0.14088350859260265 0.14088350859260265 9.568448457906033E-39 reproductive_structure_development GO:0048608 12133 216 66 3 3110 19 3 false 0.14095441896801053 0.14095441896801053 0.0 regulation_of_protein_catabolic_process GO:0042176 12133 150 66 4 1912 26 3 false 0.14133392422601945 0.14133392422601945 1.3832082048306078E-227 regulation_of_cardiac_muscle_contraction_by_calcium_ion_signaling GO:0010882 12133 16 66 1 113 1 2 false 0.14159292035398585 0.14159292035398585 9.020381142741722E-20 synaptobrevin_2-SNAP-25-syntaxin-1a-complexin_I_complex GO:0070032 12133 4 66 1 28 1 1 false 0.14285714285714302 0.14285714285714302 4.884004884004907E-5 pre-autophagosomal_structure GO:0000407 12133 16 66 1 5117 49 1 false 0.14288251190505802 0.14288251190505802 9.695449886980499E-47 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 66 40 6146 64 3 false 0.14301538754008808 0.14301538754008808 0.0 SH3/SH2_adaptor_activity GO:0005070 12133 48 66 2 126 2 2 false 0.14323809523809652 0.14323809523809652 5.926155314091347E-36 lateral_plasma_membrane GO:0016328 12133 29 66 1 1329 7 1 false 0.14340604008068522 0.14340604008068522 3.147363576559954E-60 regulation_of_cytokine_production GO:0001817 12133 323 66 5 1562 14 2 false 0.14389490304964525 0.14389490304964525 0.0 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 66 3 2191 26 3 false 0.14437616344263238 0.14437616344263238 2.495063769189982E-191 blood_vessel_endothelial_cell_migration GO:0043534 12133 53 66 3 100 3 1 false 0.14487322201607722 0.14487322201607722 1.1846448146925151E-29 cellular_response_to_ketone GO:1901655 12133 13 66 1 590 7 2 false 0.14509918775378045 0.14509918775378045 6.776870487169301E-27 zymogen_granule_membrane GO:0042589 12133 7 66 1 48 1 2 false 0.14583333333333262 0.14583333333333262 1.3581591792980692E-8 positive_regulation_of_glomerulus_development GO:0090193 12133 4 66 1 53 2 3 false 0.14658925979680634 0.14658925979680634 3.4150089643984966E-6 cell_communication_involved_in_cardiac_conduction GO:0086065 12133 21 66 1 3963 30 2 false 0.147839881328574 0.147839881328574 1.488989072793613E-56 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 66 10 1350 18 4 false 0.14787927347797258 0.14787927347797258 0.0 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 66 17 6103 64 3 false 0.14818128271441122 0.14818128271441122 0.0 energy_reserve_metabolic_process GO:0006112 12133 144 66 3 271 3 1 false 0.14855987965083234 0.14855987965083234 9.26157273052589E-81 trivalent_inorganic_cation_transport GO:0072512 12133 24 66 1 606 4 1 false 0.14959966078474574 0.14959966078474574 1.6359412389907096E-43 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 66 8 312 8 1 false 0.15062337717183003 0.15062337717183003 8.216510305576978E-69 vesicle_membrane GO:0012506 12133 312 66 4 9991 66 4 false 0.15065285878530796 0.15065285878530796 0.0 reproductive_system_development GO:0061458 12133 216 66 3 2686 17 1 false 0.15142192600272222 0.15142192600272222 0.0 positive_regulation_of_signal_transduction_by_p53_class_mediator GO:1901798 12133 11 66 1 881 13 3 false 0.15165473507298105 0.15165473507298105 1.712543759931694E-25 negative_regulation_of_epithelial_to_mesenchymal_transition GO:0010719 12133 12 66 1 79 1 3 false 0.15189873417721364 0.15189873417721364 1.9527570787405553E-14 trans-Golgi_network_transport_vesicle_membrane GO:0012510 12133 12 66 1 151 2 4 false 0.15311258278144615 0.15311258278144615 5.3388603233551054E-18 regulation_of_response_to_stress GO:0080134 12133 674 66 9 3466 32 2 false 0.15312063110291319 0.15312063110291319 0.0 negative_regulation_of_cell_death GO:0060548 12133 567 66 8 3054 29 3 false 0.15443590682639377 0.15443590682639377 0.0 cardiac_conduction GO:0061337 12133 27 66 1 657 4 2 false 0.15485714888057595 0.15485714888057595 1.5773283461446355E-48 clathrin-sculpted_gamma-aminobutyric_acid_transport_vesicle_membrane GO:0061202 12133 7 66 1 87 2 2 false 0.15530606789628804 0.15530606789628804 1.7113453422294462E-10 circulatory_system_process GO:0003013 12133 307 66 3 1272 6 1 false 0.15551523415667642 0.15551523415667642 1.974873217376429E-304 intrinsic_apoptotic_signaling_pathway_in_response_to_oxidative_stress GO:0008631 12133 11 66 1 332 5 2 false 0.1559225131509187 0.1559225131509187 8.736829109234905E-21 nucleolus_organization GO:0007000 12133 5 66 1 62 2 1 false 0.1560021152829227 0.1560021152829227 1.545355726980193E-7 vacuolar_membrane GO:0005774 12133 133 66 2 1670 9 2 false 0.1568168166221323 0.1568168166221323 7.884319611118448E-201 cell_junction_organization GO:0034330 12133 181 66 3 7663 58 2 false 0.15687233832897707 0.15687233832897707 0.0 positive_regulation_of_dephosphorylation GO:0035306 12133 12 66 1 925 13 3 false 0.15706936610354158 0.15706936610354158 1.3114534767097792E-27 transport_vesicle_membrane GO:0030658 12133 63 66 2 340 4 2 false 0.157670379878747 0.157670379878747 3.001775130471713E-70 regulation_of_cytokinesis GO:0032465 12133 27 66 1 486 3 3 false 0.15788579326529364 0.15788579326529364 6.566322229250514E-45 cellular_response_to_hypoxia GO:0071456 12133 79 66 2 1210 11 3 false 0.15800433768916408 0.15800433768916408 3.484581288071841E-126 regulation_of_bone_resorption GO:0045124 12133 21 66 1 255 2 3 false 0.15822139879570452 0.15822139879570452 3.4565530791576048E-31 ribonucleotide_catabolic_process GO:0009261 12133 946 66 10 1294 11 3 false 0.1597302132245248 0.1597302132245248 0.0 protein_heterotrimerization GO:0070208 12133 6 66 1 71 2 2 false 0.16297786720322102 0.16297786720322102 6.9823138478995105E-9 coagulation GO:0050817 12133 446 66 5 4095 27 1 false 0.16370504342242148 0.16370504342242148 0.0 response_to_ketone GO:1901654 12133 70 66 2 1822 19 2 false 0.1637643856414002 0.1637643856414002 2.649255790995827E-128 negative_regulation_of_systemic_arterial_blood_pressure GO:0003085 12133 11 66 1 67 1 2 false 0.16417910447761364 0.16417910447761364 7.781717560880856E-13 DNA_methylation GO:0006306 12133 37 66 1 225 1 4 false 0.16444444444444917 0.16444444444444917 2.946192449924989E-43 monooxygenase_activity GO:0004497 12133 81 66 1 491 1 1 false 0.1649694501018149 0.1649694501018149 6.642019443621914E-95 positive_regulation_of_lipid_transport GO:0032370 12133 23 66 1 522 4 3 false 0.16537954199639465 0.16537954199639465 1.317211240339607E-40 axon_guidance GO:0007411 12133 295 66 4 611 5 2 false 0.16573452863587282 0.16573452863587282 5.229199602535248E-183 thioesterase_binding GO:0031996 12133 12 66 1 1005 15 1 false 0.16594611462466935 0.16594611462466935 4.819194628239847E-28 protein_heterooligomerization GO:0051291 12133 55 66 2 288 4 1 false 0.1659672163522771 0.1659672163522771 1.7091560629948947E-60 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 66 7 639 10 3 false 0.16611063444951896 0.16611063444951896 1.399157780258238E-191 negative_regulation_of_cation_channel_activity GO:2001258 12133 13 66 1 222 3 3 false 0.16629570747216652 0.16629570747216652 2.8004565982805043E-21 regulation_of_angiogenesis GO:0045765 12133 127 66 2 665 4 3 false 0.1666174224775729 0.1666174224775729 3.739492527906887E-140 chaperone_cofactor-dependent_protein_refolding GO:0070389 12133 5 66 1 30 1 2 false 0.1666666666666663 0.1666666666666663 7.017248396558763E-6 cellular_response_to_interferon-gamma GO:0071346 12133 83 66 3 392 7 2 false 0.16708134557735696 0.16708134557735696 2.629901965674187E-87 regulation_of_transporter_activity GO:0032409 12133 88 66 2 2973 25 3 false 0.16795475709694946 0.16795475709694946 1.555650039308817E-171 response_to_organic_substance GO:0010033 12133 1783 66 19 2369 22 1 false 0.16806419238325696 0.16806419238325696 0.0 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 66 5 5157 34 3 false 0.1682319978025945 0.1682319978025945 0.0 regulation_of_circadian_rhythm GO:0042752 12133 27 66 1 6628 45 2 false 0.1683148324608843 0.1683148324608843 7.632819797986817E-76 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 66 4 129 5 1 false 0.16837552646035123 0.16837552646035123 2.169508265339551E-38 neuron_maturation GO:0042551 12133 26 66 1 720 5 2 false 0.16841254597852395 0.16841254597852395 3.261114080626707E-48 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 66 2 741 7 2 false 0.1691572760837359 0.1691572760837359 1.553661553762129E-109 negative_regulation_of_focal_adhesion_assembly GO:0051895 12133 9 66 1 53 1 4 false 0.16981132075471547 0.16981132075471547 2.2565144472039573E-10 U2-type_spliceosomal_complex GO:0005684 12133 3 66 1 150 9 1 false 0.1704879376020239 0.1704879376020239 1.813894431344149E-6 kinase_binding GO:0019900 12133 384 66 8 1005 15 1 false 0.1713380958513095 0.1713380958513095 2.0091697589355545E-289 trans-Golgi_network_transport_vesicle GO:0030140 12133 23 66 1 256 2 3 false 0.1719362745097841 0.1719362745097841 2.9196979468044646E-33 protein_kinase_B_binding GO:0043422 12133 9 66 1 341 7 1 false 0.17215042162535288 0.17215042162535288 6.4745360410051145E-18 skeletal_muscle_organ_development GO:0060538 12133 172 66 3 308 3 1 false 0.17280764837764112 0.17280764837764112 3.4535917571053045E-91 trans-Golgi_network_membrane GO:0032588 12133 26 66 1 9083 66 3 false 0.17293872477553252 0.17293872477553252 5.095783492585907E-77 passive_transmembrane_transporter_activity GO:0022803 12133 304 66 3 544 3 1 false 0.17375013041648396 0.17375013041648396 2.1953421087848878E-161 respiratory_burst_involved_in_inflammatory_response GO:0002536 12133 4 66 1 23 1 2 false 0.1739130434782608 0.1739130434782608 1.1293054771315566E-4 autonomic_nervous_system_development GO:0048483 12133 30 66 1 2686 17 2 false 0.17429359000532973 0.17429359000532973 4.179007035511996E-71 detection_of_calcium_ion GO:0005513 12133 10 66 1 110 2 2 false 0.17431192660550376 0.17431192660550376 2.1323036126912744E-14 regulation_of_muscle_organ_development GO:0048634 12133 106 66 2 1105 8 2 false 0.1744211322106152 0.1744211322106152 5.2870889259577626E-151 sex_determination GO:0007530 12133 21 66 1 340 3 1 false 0.17456714790432024 0.17456714790432024 6.623492102010024E-34 ATP_catabolic_process GO:0006200 12133 318 66 5 1012 10 4 false 0.1746504540263068 0.1746504540263068 1.0026310858617265E-272 urogenital_system_development GO:0001655 12133 231 66 3 2686 17 1 false 0.17483365418347024 0.17483365418347024 0.0 neuron_projection_development GO:0031175 12133 575 66 5 812 5 2 false 0.1771514499813026 0.1771514499813026 3.771933680434825E-212 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 66 22 6129 64 3 false 0.1774063752750621 0.1774063752750621 0.0 positive_regulation_of_sterol_transport GO:0032373 12133 11 66 1 62 1 3 false 0.1774193548387111 0.1774193548387111 1.967453119166065E-12 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 66 4 129 5 1 false 0.17775376915094623 0.17775376915094623 2.1037655906323275E-38 negative_regulation_of_protein_export_from_nucleus GO:0046826 12133 6 66 1 96 3 4 false 0.1777715565509501 0.1777715565509501 1.0786924431932882E-9 cellular_cation_homeostasis GO:0030003 12133 289 66 3 513 3 2 false 0.1779770487863327 0.1779770487863327 6.525965777081911E-152 trans-Golgi_network GO:0005802 12133 103 66 2 7259 54 1 false 0.17818158162806277 0.17818158162806277 4.3774465508031144E-234 positive_regulation_of_ATPase_activity GO:0032781 12133 18 66 1 837 9 3 false 0.17849042922288771 0.17849042922288771 1.8933419964451444E-37 transferase_activity GO:0016740 12133 1779 66 15 4901 33 1 false 0.17918879741379815 0.17918879741379815 0.0 endocytosis GO:0006897 12133 411 66 6 895 9 2 false 0.17924362290248957 0.17924362290248957 2.7872223899360555E-267 anatomical_structure_maturation GO:0071695 12133 32 66 1 3102 19 2 false 0.17929985460693423 0.17929985460693423 5.7189056029869944E-77 sodium_channel_regulator_activity GO:0017080 12133 14 66 1 78 1 2 false 0.17948717948717585 0.17948717948717585 9.768201397951623E-16 virion_assembly GO:0019068 12133 11 66 1 2070 37 4 false 0.18035341248054557 0.18035341248054557 1.3710102562261885E-29 response_to_progesterone_stimulus GO:0032570 12133 26 66 1 275 2 2 false 0.18046449900463885 0.18046449900463885 5.162609167223972E-37 cellular_response_to_epidermal_growth_factor_stimulus GO:0071364 12133 13 66 1 860 13 3 false 0.18079246523390555 0.18079246523390555 4.8459863580015324E-29 neuromuscular_junction GO:0031594 12133 35 66 1 368 2 1 false 0.18140623148915067 0.18140623148915067 8.605587895687818E-50 regulation_of_primary_metabolic_process GO:0080090 12133 3921 66 37 7507 63 2 false 0.1814481332004957 0.1814481332004957 0.0 branching_involved_in_mammary_gland_duct_morphogenesis GO:0060444 12133 26 66 1 143 1 2 false 0.18181818181817405 0.18181818181817405 4.1538343756792934E-29 regulation_of_endothelial_cell_migration GO:0010594 12133 69 66 3 121 3 2 false 0.1819362455726155 0.1819362455726155 1.7052033231209872E-35 response_to_DNA_damage_stimulus GO:0006974 12133 570 66 7 1124 10 1 false 0.18270356039545127 0.18270356039545127 0.0 substrate-specific_channel_activity GO:0022838 12133 291 66 3 512 3 2 false 0.18277962940308515 0.18277962940308515 2.547694139879492E-151 postsynaptic_membrane_organization GO:0001941 12133 13 66 1 784 12 1 false 0.18297154432558765 0.18297154432558765 1.6278367536663342E-28 female_gamete_generation GO:0007292 12133 65 66 1 355 1 1 false 0.18309859154930105 0.18309859154930105 7.344010792750422E-73 synaptic_vesicle_exocytosis GO:0016079 12133 30 66 1 312 2 3 false 0.18334157803610154 0.18334157803610154 1.6771400949131276E-42 protein_kinase_C_binding GO:0005080 12133 39 66 2 341 7 1 false 0.18513215339387712 0.18513215339387712 3.262596721977534E-52 channel_inhibitor_activity GO:0016248 12133 20 66 1 304 3 2 false 0.18523806894453362 0.18523806894453362 1.0141079171115058E-31 cell_adhesion_mediated_by_integrin GO:0033627 12133 47 66 1 712 3 1 false 0.18549208301536832 0.18549208301536832 1.0479034632189167E-74 dephosphorylation GO:0016311 12133 328 66 5 2776 26 1 false 0.1855294023785058 0.1855294023785058 0.0 regulation_of_cell_cycle GO:0051726 12133 659 66 7 6583 47 2 false 0.18572719939897825 0.18572719939897825 0.0 regulation_of_steroid_metabolic_process GO:0019218 12133 56 66 1 301 1 2 false 0.18604651162788827 0.18604651162788827 2.659882776337694E-62 perikaryon GO:0043204 12133 31 66 1 9983 66 2 false 0.18611770583135248 0.18611770583135248 9.08193271158762E-91 foam_cell_differentiation GO:0090077 12133 26 66 1 2154 17 1 false 0.18716206976555308 0.18716206976555308 1.0162913510282805E-60 positive_regulation_of_metanephric_glomerulus_development GO:0072300 12133 3 66 1 16 1 4 false 0.18749999999999992 0.18749999999999992 0.001785714285714283 negative_regulation_of_nuclear_division GO:0051784 12133 43 66 1 436 2 3 false 0.18772540335334276 0.18772540335334276 1.634686522119006E-60 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 66 13 3631 48 4 false 0.1881407430634608 0.1881407430634608 0.0 negative_regulation_of_apoptotic_process GO:0043066 12133 537 66 8 1377 15 3 false 0.18889328820302426 0.18889328820302426 0.0 response_to_epidermal_growth_factor_stimulus GO:0070849 12133 18 66 1 1130 13 2 false 0.1893123107888804 0.1893123107888804 8.12901015644845E-40 nucleoid GO:0009295 12133 34 66 1 10701 66 1 false 0.18996304239331768 0.18996304239331768 3.1083356769773746E-99 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 66 4 1256 24 1 false 0.190024787768869 0.190024787768869 3.1457660386089413E-171 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 66 2 2578 25 4 false 0.19135955419095235 0.19135955419095235 1.0942419479084622E-158 positive_regulation_of_lipase_activity GO:0060193 12133 104 66 2 632 5 3 false 0.19166234930162437 0.19166234930162437 4.344193956592552E-122 regulation_of_phosphoprotein_phosphatase_activity GO:0043666 12133 25 66 1 247 2 2 false 0.19255455712450345 0.19255455712450345 8.299751896094759E-35 regulation_of_anoikis GO:2000209 12133 18 66 1 1020 12 2 false 0.19331882877769965 0.19331882877769965 5.212641819611591E-39 positive_regulation_of_protein_dephosphorylation GO:0035307 12133 11 66 1 831 16 4 false 0.1935948543183997 0.1935948543183997 3.2689645244858276E-25 clathrin-coated_vesicle_membrane GO:0030665 12133 87 66 2 197 2 2 false 0.19377395628300154 0.19377395628300154 3.3450134544276105E-58 activation-induced_cell_death_of_T_cells GO:0006924 12133 7 66 1 36 1 2 false 0.19444444444444467 0.19444444444444467 1.1979376305751926E-7 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 66 6 200 16 3 false 0.19458135897683965 0.19458135897683965 7.491323649368413E-49 regulation_of_vascular_permeability GO:0043114 12133 24 66 1 2120 19 3 false 0.19527136199674583 0.19527136199674583 1.040867174042963E-56 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 66 7 1541 16 3 false 0.195794857567584 0.195794857567584 0.0 response_to_mineralocorticoid_stimulus GO:0051385 12133 20 66 1 102 1 1 false 0.19607843137254846 0.19607843137254846 1.2028902656335573E-21 ion_channel_inhibitor_activity GO:0008200 12133 20 66 1 286 3 2 false 0.19609967497291256 0.19609967497291256 3.5818833657211076E-31 positive_regulation_of_cyclic_nucleotide_metabolic_process GO:0030801 12133 80 66 2 180 2 3 false 0.19615145872126577 0.19615145872126577 3.3247573319336413E-53 neuromuscular_junction_development GO:0007528 12133 31 66 1 158 1 2 false 0.19620253164557866 0.19620253164557866 1.3366963401022166E-33 negative_regulation_of_transcription_factor_import_into_nucleus GO:0042992 12133 34 66 2 76 2 3 false 0.19684210526315704 0.19684210526315704 2.199973770519916E-22 lipoprotein_lipase_activity GO:0004465 12133 23 66 1 222 2 2 false 0.1968937263054701 0.1968937263054701 9.097839743552619E-32 skeletal_muscle_tissue_development GO:0007519 12133 168 66 3 288 3 2 false 0.19701233725620948 0.19701233725620948 2.348024843062379E-84 SNARE_complex GO:0031201 12133 28 66 1 7525 59 3 false 0.19812134052587027 0.19812134052587027 9.200280097492742E-80 anoikis GO:0043276 12133 20 66 1 1373 15 1 false 0.19847987267193853 0.19847987267193853 4.932867438631412E-45 Golgi_membrane GO:0000139 12133 322 66 3 1835 9 3 false 0.19893654824177007 0.19893654824177007 0.0 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 66 2 2735 29 4 false 0.19962497231941756 0.19962497231941756 2.836340851870023E-153 postreplication_repair GO:0006301 12133 16 66 1 368 5 1 false 0.20028861513027715 0.20028861513027715 2.574562678585272E-28 isomerase_activity GO:0016853 12133 123 66 2 4901 33 1 false 0.20031424252812485 0.20031424252812485 7.077862449152851E-249 positive_regulation_of_lymphocyte_activation GO:0051251 12133 188 66 2 419 2 3 false 0.2007285516895596 0.2007285516895596 1.71987955515036E-124 positive_regulation_of_T_cell_activation GO:0050870 12133 145 66 2 323 2 3 false 0.20075764859720874 0.20075764859720874 7.1027996669547384E-96 protein_binding_transcription_factor_activity GO:0000988 12133 488 66 5 10311 66 3 false 0.2016104579358245 0.2016104579358245 0.0 negative_regulation_of_anoikis GO:2000811 12133 15 66 1 542 8 3 false 0.20228823212934388 0.20228823212934388 1.5538364959648575E-29 regulation_of_response_to_cytokine_stimulus GO:0060759 12133 76 66 2 2275 25 2 false 0.20242748187771084 0.20242748187771084 4.9547358949088833E-144 spindle_pole GO:0000922 12133 87 66 2 3232 31 3 false 0.20245316184227918 0.20245316184227918 3.214023535487519E-173 SCF-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031146 12133 16 66 1 220 3 1 false 0.20355775931997488 0.20355775931997488 1.2148210927332739E-24 DNA_replication_preinitiation_complex GO:0031261 12133 28 66 1 877 7 3 false 0.20381869231936922 0.20381869231936922 1.8592053486968803E-53 receptor_binding GO:0005102 12133 918 66 10 6397 52 1 false 0.20428862209122914 0.20428862209122914 0.0 cell_junction_assembly GO:0034329 12133 159 66 3 1406 14 2 false 0.2045806906755188 0.2045806906755188 9.423437086545545E-215 phosphatidylinositol_3-kinase_binding GO:0043548 12133 28 66 1 6397 52 1 false 0.2046893517203439 0.2046893517203439 8.759965627665317E-78 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 66 2 195 3 4 false 0.2050416438964213 0.2050416438964213 1.081664723883568E-50 divalent_inorganic_cation_transmembrane_transporter_activity GO:0072509 12133 126 66 2 431 3 2 false 0.205822613150166 0.205822613150166 1.8747555941678357E-112 regulation_of_viral_reproduction GO:0050792 12133 101 66 2 6451 54 3 false 0.20691243476799692 0.20691243476799692 3.49743359338843E-225 positive_regulation_of_blood_vessel_endothelial_cell_migration GO:0043536 12133 21 66 2 71 3 3 false 0.2069810165339874 0.2069810165339874 1.8270708961531386E-18 regulation_of_muscle_tissue_development GO:1901861 12133 105 66 2 1351 11 2 false 0.2083144509752561 0.2083144509752561 1.3105194568745759E-159 leukocyte_migration GO:0050900 12133 224 66 4 1975 21 2 false 0.20835183772859278 0.20835183772859278 1.7898344026900835E-302 multivesicular_body_sorting_pathway GO:0071985 12133 17 66 1 2490 34 2 false 0.20902380185656538 0.20902380185656538 6.909596477174519E-44 regulation_of_metanephros_development GO:0072215 12133 18 66 1 86 1 2 false 0.20930232558139594 0.20930232558139594 6.553866278525698E-19 response_to_peptide GO:1901652 12133 322 66 4 904 7 2 false 0.2093714498193442 0.2093714498193442 7.8711156655671515E-255 regulation_of_cell_migration_involved_in_sprouting_angiogenesis GO:0090049 12133 11 66 1 147 3 3 false 0.20943190691486474 0.20943190691486474 8.456079340960635E-17 deacetylase_activity GO:0019213 12133 35 66 1 2556 17 1 false 0.2095366819478374 0.2095366819478374 7.098365746650995E-80 regulation_of_NIK/NF-kappaB_cascade GO:1901222 12133 17 66 1 1605 22 2 false 0.21007667757073833 0.21007667757073833 1.2442844653745033E-40 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 66 4 7778 58 4 false 0.21041809131615868 0.21041809131615868 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 66 12 1180 27 1 false 0.21069147115583226 0.21069147115583226 0.0 mesenchymal_cell_differentiation GO:0048762 12133 118 66 2 256 2 2 false 0.2114889705882156 0.2114889705882156 3.77778946596228E-76 response_to_cold GO:0009409 12133 25 66 1 2544 24 2 false 0.21187532728435587 0.21187532728435587 1.270858440616409E-60 regulation_of_cytokine-mediated_signaling_pathway GO:0001959 12133 70 66 2 1785 22 3 false 0.21244021405713825 0.21244021405713825 1.145730192869727E-127 programmed_cell_death GO:0012501 12133 1385 66 16 1525 16 1 false 0.21251993588330054 0.21251993588330054 2.142172117700311E-202 ATP-dependent_helicase_activity GO:0008026 12133 98 66 3 228 4 2 false 0.21325169772118874 0.21325169772118874 4.1384935546953996E-67 protein_refolding GO:0042026 12133 14 66 1 183 3 1 false 0.2134770401231755 0.2134770401231755 3.073045199995708E-21 response_to_interferon-gamma GO:0034341 12133 97 66 3 900 15 2 false 0.213651378009561 0.213651378009561 5.665951698458868E-133 excretion GO:0007588 12133 50 66 1 1272 6 1 false 0.21423188979551736 0.21423188979551736 4.8139348402185623E-91 regulation_of_macrophage_derived_foam_cell_differentiation GO:0010743 12133 23 66 1 874 9 2 false 0.21426432526667777 0.21426432526667777 7.665512649099911E-46 monocyte_chemotaxis GO:0002548 12133 23 66 1 107 1 1 false 0.21495327102804263 0.21495327102804263 6.985599683738772E-24 protein_complex_subunit_organization GO:0071822 12133 989 66 21 1256 24 1 false 0.2150435393496859 0.2150435393496859 2.2763776011987297E-281 cellular_carbohydrate_catabolic_process GO:0044275 12133 48 66 1 223 1 2 false 0.21524663677131184 0.21524663677131184 5.586362156501389E-50 ubiquitin-dependent_protein_catabolic_process_via_the_multivesicular_body_sorting_pathway GO:0043162 12133 10 66 1 379 9 3 false 0.2159401342258574 0.2159401342258574 6.689174917849262E-20 regulation_of_osteoblast_differentiation GO:0045667 12133 89 66 2 913 9 3 false 0.21609041444574567 0.21609041444574567 4.590259289121949E-126 glutamate_receptor_binding GO:0035254 12133 22 66 1 918 10 1 false 0.2163414331882853 0.2163414331882853 9.51424084577774E-45 nuclear_pre-replicative_complex GO:0005656 12133 28 66 1 821 7 4 false 0.216361331928128 0.216361331928128 1.2155097168867057E-52 response_to_abiotic_stimulus GO:0009628 12133 676 66 7 5200 38 1 false 0.21718214222414495 0.21718214222414495 0.0 progesterone_receptor_signaling_pathway GO:0050847 12133 6 66 1 102 4 1 false 0.21828418135930974 0.21828418135930974 7.426393311971009E-10 nucleoside_phosphate_binding GO:1901265 12133 1998 66 23 4407 44 2 false 0.21831249634361277 0.21831249634361277 0.0 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 66 7 5830 42 3 false 0.2197795457753834 0.2197795457753834 0.0 negative_regulation_of_transporter_activity GO:0032410 12133 27 66 1 1543 14 4 false 0.21979813617755556 0.21979813617755556 1.1232233083477821E-58 positive_regulation_of_cholesterol_transport GO:0032376 12133 11 66 1 50 1 3 false 0.219999999999998 0.219999999999998 2.677108188163444E-11 ion_channel_activity GO:0005216 12133 286 66 3 473 3 2 false 0.2201431551884613 0.2201431551884613 3.7303800171637374E-137 negative_regulation_of_intracellular_transport GO:0032387 12133 72 66 3 1281 29 3 false 0.22018654116105107 0.22018654116105107 8.445033635932749E-120 regulation_of_protein_stability GO:0031647 12133 99 66 2 2240 20 2 false 0.22033200728278846 0.22033200728278846 1.7785498552391114E-175 vacuolar_protein_catabolic_process GO:0007039 12133 10 66 1 409 10 1 false 0.22146311282083017 0.22146311282083017 3.095189671373722E-20 multicellular_organismal_homeostasis GO:0048871 12133 128 66 2 4332 30 2 false 0.2217110255047552 0.2217110255047552 8.184767611609268E-250 negative_regulation_of_DNA_binding GO:0043392 12133 35 66 1 2119 15 3 false 0.22171568721833074 0.22171568721833074 5.275494739019896E-77 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 66 2 206 3 2 false 0.2221657310804987 0.2221657310804987 1.364605297408496E-54 protein_serine/threonine_phosphatase_complex GO:0008287 12133 38 66 1 10006 66 2 false 0.22271452128263708 0.22271452128263708 5.4849454028851035E-108 regulation_of_organelle_assembly GO:1902115 12133 25 66 1 807 8 3 false 0.22342936441271077 0.22342936441271077 4.807442974661034E-48 mitogen-activated_protein_kinase_kinase_binding GO:0031434 12133 12 66 1 341 7 1 false 0.22356999889917795 0.22356999889917795 2.356690583847287E-22 regulation_of_protein_oligomerization GO:0032459 12133 22 66 1 447 5 2 false 0.22393050729694464 0.22393050729694464 9.37826543019211E-38 peptidyl-tyrosine_modification GO:0018212 12133 191 66 2 623 3 1 false 0.22394604156480657 0.22394604156480657 5.019013158282893E-166 fertilization GO:0009566 12133 65 66 1 546 2 2 false 0.2241153342071744 0.2241153342071744 5.279047514007133E-86 negative_regulation_of_cytokine-mediated_signaling_pathway GO:0001960 12133 21 66 1 839 10 4 false 0.22498373453092332 0.22498373453092332 2.6238685754498578E-42 positive_regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043517 12133 11 66 1 135 3 4 false 0.22661379817704372 0.22661379817704372 2.2345648964968075E-16 anatomical_structure_homeostasis GO:0060249 12133 166 66 3 990 10 1 false 0.22689610005175292 0.22689610005175292 1.128853988781411E-193 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 66 4 1097 21 3 false 0.22691648563476113 0.22691648563476113 8.208279871491876E-172 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 66 1 22 1 1 false 0.22727272727272646 0.22727272727272646 3.79737221842484E-5 lipase_activity GO:0016298 12133 187 66 2 814 4 1 false 0.22770331830758556 0.22770331830758556 8.941328372617339E-190 myosin_binding GO:0017022 12133 28 66 1 556 5 1 false 0.2284232654688578 0.2284232654688578 8.361733293720516E-48 binding,_bridging GO:0060090 12133 129 66 2 8962 63 1 false 0.22962028917622987 0.22962028917622987 1.7318913122999068E-292 positive_regulation_of_epithelial_cell_migration GO:0010634 12133 62 66 2 268 4 3 false 0.22971006219436632 0.22971006219436632 1.921249223488317E-62 regulation_of_cellular_localization GO:0060341 12133 603 66 7 6869 57 3 false 0.23073407432860898 0.23073407432860898 0.0 negative_regulation_of_hydrolase_activity GO:0051346 12133 241 66 3 2738 19 3 false 0.23083158091097195 0.23083158091097195 0.0 muscle_structure_development GO:0061061 12133 413 66 4 3152 19 2 false 0.23141674632337592 0.23141674632337592 0.0 negative_regulation_of_calcium_ion_transmembrane_transporter_activity GO:1901020 12133 15 66 1 122 2 3 false 0.23167592467145925 0.23167592467145925 1.6241841544551345E-19 hormone_secretion GO:0046879 12133 183 66 2 585 3 3 false 0.23193253287596194 0.23193253287596194 3.893297614002336E-157 negative_regulation_of_peptidyl-tyrosine_phosphorylation GO:0050732 12133 30 66 1 357 3 3 false 0.2321044575450385 0.2321044575450385 2.443461883518979E-44 cell_leading_edge GO:0031252 12133 252 66 3 9983 66 1 false 0.23237689968256672 0.23237689968256672 0.0 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 66 2 695 8 3 false 0.23239127153701433 0.23239127153701433 3.5521820546065696E-107 regulation_of_muscle_system_process GO:0090257 12133 112 66 1 481 1 2 false 0.23284823284823153 0.23284823284823153 9.996580757849421E-113 leukocyte_apoptotic_process GO:0071887 12133 63 66 1 270 1 1 false 0.23333333333332495 0.23333333333332495 3.449677973772266E-63 receptor_clustering GO:0043113 12133 22 66 1 94 1 1 false 0.23404255319149544 0.23404255319149544 6.3297515155617905E-22 purine_nucleoside_catabolic_process GO:0006152 12133 939 66 10 1085 10 3 false 0.23417480950995523 0.23417480950995523 2.1746006434797338E-185 cellular_monovalent_inorganic_cation_homeostasis GO:0030004 12133 26 66 1 306 3 2 false 0.23455818910822637 0.23455818910822637 2.8281153145438213E-38 protein_K6-linked_ubiquitination GO:0085020 12133 7 66 1 163 6 1 false 0.23478003142656126 0.23478003142656126 1.878573514862509E-12 lipid_storage GO:0019915 12133 43 66 1 181 1 1 false 0.23756906077349124 0.23756906077349124 1.1493804978494703E-42 Notch_receptor_processing GO:0007220 12133 17 66 1 3038 48 1 false 0.23773695170703799 0.23773695170703799 2.325698863690895E-45 cation_homeostasis GO:0055080 12133 330 66 3 532 3 1 false 0.23784918003369943 0.23784918003369943 1.1320770482912473E-152 regulation_of_epithelial_to_mesenchymal_transition GO:0010717 12133 37 66 1 975 7 4 false 0.23789133021221592 0.23789133021221592 7.014478245035562E-68 vacuole GO:0005773 12133 310 66 4 8213 66 2 false 0.2379196309227422 0.2379196309227422 0.0 ubiquitin-protein_ligase_activity GO:0004842 12133 321 66 8 558 11 2 false 0.23853617950302533 0.23853617950302533 1.7708856343357755E-164 regulation_of_cell_adhesion GO:0030155 12133 244 66 3 6487 45 2 false 0.23889924479850677 0.23889924479850677 0.0 phosphoric_diester_hydrolase_activity GO:0008081 12133 142 66 2 446 3 1 false 0.23902611736534862 0.23902611736534862 1.6123657849683337E-120 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 66 2 1056 13 3 false 0.23916018352045224 0.23916018352045224 4.764817151311381E-118 negative_regulation_of_blood_pressure GO:0045776 12133 28 66 1 117 1 1 false 0.2393162393162351 0.2393162393162351 1.267799191286988E-27 sodium_ion_homeostasis GO:0055078 12133 26 66 1 299 3 2 false 0.23957403035316438 0.23957403035316438 5.299686091705976E-38 M_phase GO:0000279 12133 22 66 1 253 3 1 false 0.23970783532531656 0.23970783532531656 3.8938574183719536E-32 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 66 7 1398 19 2 false 0.24029959602917128 0.24029959602917128 0.0 response_to_temperature_stimulus GO:0009266 12133 91 66 2 676 7 1 false 0.2403633182185817 0.2403633182185817 2.3046402907653703E-115 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 66 4 129 5 1 false 0.24052160267757036 0.24052160267757036 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 66 4 129 5 1 false 0.24052160267757036 0.24052160267757036 3.3394798770258706E-38 cell-cell_junction_assembly GO:0007043 12133 58 66 2 181 3 2 false 0.24092821794909877 0.24092821794909877 7.851737058026464E-49 ribosome_assembly GO:0042255 12133 16 66 1 417 7 3 false 0.24111458357968082 0.24111458357968082 3.349634512578164E-29 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 66 8 3605 51 4 false 0.241503621214747 0.241503621214747 0.0 mesenchyme_development GO:0060485 12133 139 66 2 2065 14 2 false 0.2419820487931033 0.2419820487931033 1.8744304993238498E-220 negative_regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001243 12133 8 66 1 150 5 3 false 0.2426093386100982 0.2426093386100982 1.902149109321368E-13 negative_regulation_of_inflammatory_response GO:0050728 12133 56 66 1 432 2 4 false 0.24271719515341908 0.24271719515341908 7.653768457766755E-72 protein_binding,_bridging GO:0030674 12133 116 66 2 6397 52 2 false 0.24294287496261557 0.24294287496261557 3.1111419589573665E-251 NIK/NF-kappaB_cascade GO:0038061 12133 24 66 1 1828 21 2 false 0.24351835725340482 0.24351835725340482 3.725046499789671E-55 ATP_metabolic_process GO:0046034 12133 381 66 5 1209 11 3 false 0.24394985219659193 0.24394985219659193 0.0 hippocampus_development GO:0021766 12133 46 66 1 3152 19 4 false 0.24431763490063105 0.24431763490063105 8.889994332374666E-104 negative_regulation_of_proteasomal_protein_catabolic_process GO:1901799 12133 18 66 1 267 4 4 false 0.24483754532510918 0.24483754532510918 2.4189460284559847E-28 caveola GO:0005901 12133 54 66 1 1371 7 2 false 0.24566440325403158 0.24566440325403158 2.6461252387361787E-98 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 66 2 6380 45 3 false 0.24636537495075053 0.24636537495075053 2.5067679665083333E-283 response_to_dsRNA GO:0043331 12133 36 66 1 784 6 2 false 0.2464512093883729 0.2464512093883729 5.364553057081943E-63 positive_regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0090263 12133 41 66 1 166 1 3 false 0.24698795180724134 0.24698795180724134 6.994942788129516E-40 regulation_of_glomerulus_development GO:0090192 12133 10 66 1 76 2 2 false 0.24736842105262835 0.24736842105262835 1.0476395999303413E-12 ribonucleoprotein_granule GO:0035770 12133 75 66 2 3365 43 2 false 0.24859229142957426 0.24859229142957426 1.704323678285534E-155 regulation_of_biological_process GO:0050789 12133 6622 66 45 10446 66 2 false 0.2496929748722315 0.2496929748722315 0.0 UBC13-MMS2_complex GO:0031372 12133 2 66 1 8 1 1 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 UBC13-UEV1A_complex GO:0035370 12133 2 66 1 8 1 1 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 homophilic_cell_adhesion GO:0007156 12133 71 66 1 284 1 1 false 0.25000000000001327 0.25000000000001327 8.027709869164102E-69 coated_membrane GO:0048475 12133 66 66 1 4398 19 1 false 0.2501519932034113 0.2501519932034113 3.1181974111959693E-148 regulation_of_cell_motility GO:2000145 12133 370 66 5 831 8 3 false 0.25037063000368315 0.25037063000368315 3.695619588048616E-247 cyclic-nucleotide_phosphodiesterase_activity GO:0004112 12133 19 66 1 142 2 1 false 0.25052442313454554 0.25052442313454554 5.481776631044377E-24 negative_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043124 12133 32 66 2 297 9 3 false 0.2511758192418806 0.2511758192418806 1.1075051157890655E-43 regulation_of_potassium_ion_transport GO:0043266 12133 32 66 1 238 2 2 false 0.2513207814771204 0.2513207814771204 2.0777607490676014E-40 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 66 8 1399 16 3 false 0.25197471262692106 0.25197471262692106 0.0 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 66 4 129 5 1 false 0.25205693401696594 0.25205693401696594 4.0186961232005657E-38 regulation_of_ATPase_activity GO:0043462 12133 26 66 1 1091 12 4 false 0.25242926847645997 0.25242926847645997 5.656765596818151E-53 negative_regulation_of_innate_immune_response GO:0045824 12133 14 66 1 685 14 4 false 0.25316047103797046 0.25316047103797046 1.989838073929195E-29 tube_morphogenesis GO:0035239 12133 260 66 3 2815 19 3 false 0.2535322688162886 0.2535322688162886 0.0 catalytic_step_2_spliceosome GO:0071013 12133 76 66 6 151 9 3 false 0.2537922886865387 0.2537922886865387 5.422089502503699E-45 negative_regulation_of_response_to_cytokine_stimulus GO:0060761 12133 25 66 1 1041 12 3 false 0.2541815464295053 0.2541815464295053 7.595002579363509E-51 intracellular_ligand-gated_ion_channel_activity GO:0005217 12133 30 66 1 118 1 1 false 0.2542372881355917 0.2542372881355917 1.050262137135434E-28 pre-replicative_complex GO:0036387 12133 28 66 1 110 1 1 false 0.2545454545454507 0.2545454545454507 9.125355053770069E-27 ribosomal_small_subunit_assembly GO:0000028 12133 6 66 1 128 6 3 false 0.2547186866934553 0.2547186866934553 1.8437899825856603E-10 sterol_transport GO:0015918 12133 50 66 1 196 1 2 false 0.25510204081633736 0.25510204081633736 7.03456997808392E-48 osteoblast_differentiation GO:0001649 12133 126 66 2 2191 17 2 false 0.25553753353624076 0.25553753353624076 1.111366645898294E-208 chromosome,_telomeric_region GO:0000781 12133 48 66 1 512 3 1 false 0.256159347300493 0.256159347300493 1.088424225361165E-68 replication_fork GO:0005657 12133 48 66 1 512 3 1 false 0.256159347300493 0.256159347300493 1.088424225361165E-68 endothelium_development GO:0003158 12133 41 66 1 1132 8 1 false 0.2562601231533251 0.2562601231533251 4.316589414530117E-76 phosphatase_regulator_activity GO:0019208 12133 58 66 1 1010 5 2 false 0.25644157817375524 0.25644157817375524 7.00162504875011E-96 long-chain_fatty_acid_metabolic_process GO:0001676 12133 55 66 1 214 1 1 false 0.2570093457944013 0.2570093457944013 1.7338944688628492E-52 positive_regulation_of_chromosome_organization GO:2001252 12133 49 66 1 847 5 3 false 0.2582092593129238 0.2582092593129238 8.5635846172251E-81 small_ribosomal_subunit GO:0015935 12133 60 66 8 132 14 1 false 0.25877063783937637 0.25877063783937637 4.556510204279982E-39 regulation_of_tight_junction_assembly GO:2000810 12133 8 66 1 58 2 2 false 0.25892316999395243 0.25892316999395243 5.217035699399583E-10 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 66 4 2776 26 3 false 0.25937518423646094 0.25937518423646094 0.0 regulation_of_vasculature_development GO:1901342 12133 141 66 2 1139 8 2 false 0.259719438805404 0.259719438805404 1.7255097841170828E-184 regulation_of_cellular_process GO:0050794 12133 6304 66 45 9757 65 2 false 0.2598655215055908 0.2598655215055908 0.0 negative_regulation_of_ligase_activity GO:0051352 12133 71 66 2 1003 14 3 false 0.2604301237908384 0.2604301237908384 8.698138776450475E-111 gonad_development GO:0008406 12133 150 66 2 2876 19 4 false 0.26065840887007174 0.26065840887007174 4.529833702866928E-255 extrinsic_to_membrane GO:0019898 12133 111 66 1 2995 8 1 false 0.26102303838310476 0.26102303838310476 1.8304176420472748E-205 cyclooxygenase_pathway GO:0019371 12133 11 66 1 42 1 2 false 0.261904761904763 0.261904761904763 2.336142183608801E-10 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 66 14 1304 15 1 false 0.26384779567628136 0.26384779567628136 1.004636319027547E-252 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 66 3 1376 15 3 false 0.2645637502449577 0.2645637502449577 2.059495184181185E-218 regulation_of_transcription_factor_import_into_nucleus GO:0042990 12133 63 66 2 122 2 2 false 0.26459829291424314 0.26459829291424314 2.784334919854664E-36 mRNA_export_from_nucleus GO:0006406 12133 60 66 2 116 2 2 false 0.2653673163418319 0.2653673163418319 1.7435958103584361E-34 signaling_adaptor_activity GO:0035591 12133 65 66 2 839 13 2 false 0.26656488629761943 0.26656488629761943 9.48818477040309E-99 immune_response-activating_signal_transduction GO:0002757 12133 299 66 8 352 8 2 false 0.2671826586805798 0.2671826586805798 2.8561568566531905E-64 synaptic_transmission GO:0007268 12133 515 66 4 923 5 2 false 0.2676532626466668 0.2676532626466668 2.6714189194289816E-274 oxidoreductase_activity,_acting_on_paired_donors,_with_incorporation_or_reduction_of_molecular_oxygen GO:0016705 12133 132 66 1 491 1 1 false 0.2688391038696182 0.2688391038696182 1.8422051059015865E-123 purine_nucleotide_catabolic_process GO:0006195 12133 956 66 10 1223 11 3 false 0.26985561493765525 0.26985561493765525 6.80299167777575E-278 cell_differentiation_involved_in_kidney_development GO:0061005 12133 40 66 1 2189 17 2 false 0.2699773638274895 0.2699773638274895 2.8675090543885934E-86 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 66 4 3568 34 3 false 0.2709340290149115 0.2709340290149115 0.0 fatty_acid_derivative_biosynthetic_process GO:1901570 12133 31 66 1 4152 42 2 false 0.27118166038823166 0.27118166038823166 6.277722100859956E-79 integral_to_plasma_membrane GO:0005887 12133 801 66 2 2339 3 2 false 0.2714107774970916 0.2714107774970916 0.0 regulation_of_organelle_organization GO:0033043 12133 519 66 5 2487 17 2 false 0.27145601135381264 0.27145601135381264 0.0 extracellular_vesicular_exosome GO:0070062 12133 58 66 1 763 4 2 false 0.27158906822018636 0.27158906822018636 1.4131645972383266E-88 calcium_ion_transmembrane_transport GO:0070588 12133 131 66 2 640 5 2 false 0.27205276432476744 0.27205276432476744 3.4276218198079466E-140 regulation_of_signal_transduction_by_p53_class_mediator GO:1901796 12133 24 66 1 1685 22 2 false 0.2721091157846276 0.2721091157846276 2.665493557536061E-54 regulation_of_tyrosine_phosphorylation_of_STAT_protein GO:0042509 12133 46 66 1 169 1 3 false 0.2721893491124171 0.2721893491124171 1.5655998786815088E-42 ureter_maturation GO:0035799 12133 3 66 1 11 1 2 false 0.27272727272727315 0.27272727272727315 0.006060606060606057 positive_regulation_of_locomotion GO:0040017 12133 216 66 3 3440 29 3 false 0.2730174112557717 0.2730174112557717 0.0 protein_trimerization GO:0070206 12133 22 66 1 288 4 1 false 0.2735563894099662 0.2735563894099662 2.002068954416936E-33 regulation_of_protein_autophosphorylation GO:0031952 12133 21 66 1 870 13 2 false 0.27376504696289966 0.27376504696289966 1.2136753132364896E-42 positive_regulation_of_leukocyte_proliferation GO:0070665 12133 92 66 1 621 2 3 false 0.274551971326197 0.274551971326197 1.6338655399895727E-112 morphogenesis_of_an_epithelium GO:0002009 12133 328 66 3 691 4 2 false 0.27491081541308776 0.27491081541308776 7.776670515222191E-207 regulation_of_developmental_process GO:0050793 12133 1233 66 10 7209 47 2 false 0.27554358144139657 0.27554358144139657 0.0 sodium_channel_activity GO:0005272 12133 26 66 1 256 3 3 false 0.2757570055580811 0.2757570055580811 3.647595212320824E-36 calcium-release_channel_activity GO:0015278 12133 26 66 1 175 2 2 false 0.27579638752052504 0.27579638752052504 1.3660960212316165E-31 negative_regulation_of_intracellular_protein_kinase_cascade GO:0010741 12133 140 66 3 1142 15 3 false 0.2759246605877928 0.2759246605877928 8.254846485029262E-184 regulation_of_heart_contraction GO:0008016 12133 108 66 1 391 1 2 false 0.27621483375957145 0.27621483375957145 1.86290960303053E-99 negative_regulation_of_protein_transport GO:0051224 12133 90 66 3 1225 25 3 false 0.2766941479786745 0.2766941479786745 4.959816028960601E-139 mesenchymal_cell_development GO:0014031 12133 106 66 2 201 2 2 false 0.27686567164176223 0.27686567164176223 7.469742798600782E-60 Golgi-associated_vesicle_membrane GO:0030660 12133 29 66 1 553 6 3 false 0.27726264280147633 0.27726264280147633 5.3948858906392845E-49 cellular_polysaccharide_catabolic_process GO:0044247 12133 24 66 1 86 1 3 false 0.27906976744186296 0.27906976744186296 8.059362586714989E-22 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 66 9 10311 66 3 false 0.27983478659772987 0.27983478659772987 0.0 K63-linked_polyubiquitin_binding GO:0070530 12133 7 66 1 25 1 1 false 0.28000000000000047 0.28000000000000047 2.08029956313708E-6 hippo_signaling_cascade GO:0035329 12133 28 66 1 1813 21 1 false 0.2801307733823359 0.2801307733823359 2.187819615524224E-62 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 66 8 3910 51 3 false 0.2804940765512905 0.2804940765512905 0.0 microtubule_associated_complex GO:0005875 12133 110 66 2 3267 31 3 false 0.2805975160926469 0.2805975160926469 2.821671595839563E-208 Golgi-associated_vesicle GO:0005798 12133 52 66 1 975 6 2 false 0.28087459724867864 0.28087459724867864 1.201522273090165E-87 regulation_of_tissue_remodeling GO:0034103 12133 36 66 1 1553 14 2 false 0.28089836290138875 0.28089836290138875 7.34343779200805E-74 late_endosome GO:0005770 12133 119 66 2 455 4 1 false 0.28092334995589935 0.28092334995589935 6.550278762678856E-113 regulation_of_lipid_storage GO:0010883 12133 29 66 1 1250 14 2 false 0.28134132968121894 0.28134132968121894 1.8979804083255723E-59 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 66 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 ribonucleoside_catabolic_process GO:0042454 12133 946 66 10 1073 10 2 false 0.28213272250587995 0.28213272250587995 9.25790942536024E-169 histone_deacetylation GO:0016575 12133 48 66 1 314 2 2 false 0.2827781282431661 0.2827781282431661 7.70276345269051E-58 nuclear_ubiquitin_ligase_complex GO:0000152 12133 24 66 1 2846 39 2 false 0.2828797716665149 0.2828797716665149 8.576333877178578E-60 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 66 10 1202 11 3 false 0.28407098654421503 0.28407098654421503 1.616697592155103E-269 ATPase_binding GO:0051117 12133 22 66 1 1005 15 1 false 0.28420878729404736 0.28420878729404736 1.2695671951618567E-45 regulation_of_RNA_stability GO:0043487 12133 37 66 1 2240 20 2 false 0.28433918973453814 0.28433918973453814 2.0388833014238124E-81 negative_regulation_of_intracellular_protein_transport GO:0090317 12133 59 66 3 695 22 4 false 0.28473084846581426 0.28473084846581426 3.676422199192608E-87 single-organism_carbohydrate_catabolic_process GO:0044724 12133 110 66 1 386 1 2 false 0.2849740932642283 0.2849740932642283 1.4747416896601825E-99 unsaturated_fatty_acid_metabolic_process GO:0033559 12133 61 66 1 214 1 1 false 0.28504672897196576 0.28504672897196576 4.719714770473024E-55 chaperone_binding GO:0051087 12133 41 66 1 6397 52 1 false 0.28516119318822203 0.28516119318822203 3.429149968401103E-107 mitochondrial_nucleoid GO:0042645 12133 31 66 1 3636 39 4 false 0.2851616259308753 0.2851616259308753 3.9028204500854244E-77 multicellular_organismal_response_to_stress GO:0033555 12133 47 66 1 5076 36 2 false 0.2854137228411577 0.2854137228411577 2.217808696530823E-115 mammary_gland_morphogenesis GO:0060443 12133 50 66 1 175 1 2 false 0.2857142857142999 0.2857142857142999 5.092262443140402E-45 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 66 2 676 13 2 false 0.2860655965727774 0.2860655965727774 2.737610529852072E-82 coated_pit GO:0005905 12133 52 66 1 10213 66 3 false 0.28679056528739044 0.28679056528739044 3.070128605674566E-141 regulation_of_steroid_biosynthetic_process GO:0050810 12133 42 66 1 146 1 3 false 0.2876712328767199 0.2876712328767199 1.231507741439357E-37 kidney_development GO:0001822 12133 161 66 2 2877 19 3 false 0.28808932092457523 0.28808932092457523 9.385342690705625E-269 negative_regulation_of_mitosis GO:0045839 12133 43 66 1 656 5 5 false 0.28826787318324154 0.28826787318324154 1.8426541499010044E-68 response_to_amine_stimulus GO:0014075 12133 34 66 1 519 5 1 false 0.28832492752417815 0.28832492752417815 4.3087725202011926E-54 response_to_virus GO:0009615 12133 230 66 3 475 4 1 false 0.28835689788815666 0.28835689788815666 3.548520767075247E-142 development_of_primary_sexual_characteristics GO:0045137 12133 174 66 2 3105 19 3 false 0.2886482231443148 0.2886482231443148 2.1612319791507408E-290 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 66 5 673 7 2 false 0.2894159357121168 0.2894159357121168 4.9348138289436974E-201 microtubule GO:0005874 12133 288 66 4 3267 31 3 false 0.28979040153006397 0.28979040153006397 0.0 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 66 10 1054 10 2 false 0.29060975842205355 0.29060975842205355 2.3625686453162704E-163 regulation_of_hydrolase_activity GO:0051336 12133 821 66 8 3094 24 2 false 0.2910870315774377 0.2910870315774377 0.0 cell_communication_by_electrical_coupling_involved_in_cardiac_conduction GO:0086064 12133 7 66 1 24 1 2 false 0.29166666666666574 0.29166666666666574 2.889304948801504E-6 response_to_hypoxia GO:0001666 12133 200 66 3 2540 24 2 false 0.29185728810394485 0.29185728810394485 2.6634431659671552E-303 cellular_response_to_oxygen_levels GO:0071453 12133 85 66 2 1663 21 2 false 0.29189214964661064 0.29189214964661064 4.192529980934564E-145 T_cell_receptor_signaling_pathway GO:0050852 12133 88 66 5 112 5 1 false 0.2920213791773309 0.2920213791773309 5.828412725788921E-25 unsaturated_fatty_acid_biosynthetic_process GO:0006636 12133 33 66 1 113 1 2 false 0.2920353982300976 0.2920353982300976 2.7853278373724977E-29 DNA-dependent_transcription,_termination GO:0006353 12133 80 66 2 2751 37 2 false 0.2926671291715629 0.2926671291715629 1.5820458311792457E-156 single_organism_signaling GO:0044700 12133 3878 66 30 8052 57 2 false 0.2927682314160055 0.2927682314160055 0.0 regulation_of_Rac_protein_signal_transduction GO:0035020 12133 23 66 1 278 4 2 false 0.29347323585177565 0.29347323585177565 4.034778444759645E-34 spliceosomal_complex_assembly GO:0000245 12133 38 66 3 259 13 2 false 0.2937371180397309 0.2937371180397309 1.791986159229858E-46 kidney_epithelium_development GO:0072073 12133 57 66 1 684 4 2 false 0.29449809772826663 0.29449809772826663 1.1272340950274278E-84 Wnt_receptor_signaling_pathway GO:0016055 12133 260 66 4 1975 21 1 false 0.2954984426593106 0.2954984426593106 0.0 positive_regulation_of_calcium_ion_transmembrane_transporter_activity GO:1901021 12133 14 66 1 128 3 3 false 0.2956036745406865 0.2956036745406865 5.750295984556454E-19 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 66 10 1060 10 3 false 0.2959417563300423 0.2959417563300423 8.715047292960447E-163 nuclear_envelope_reassembly GO:0031468 12133 8 66 1 27 1 1 false 0.2962962962962964 0.2962962962962964 4.504352330439255E-7 activation_of_protein_kinase_activity GO:0032147 12133 247 66 6 417 8 1 false 0.2974544018734687 0.2974544018734687 9.475379918718814E-122 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 66 1 222 2 3 false 0.29864253393661766 0.29864253393661766 2.5456303013282065E-42 cellular_response_to_insulin_stimulus GO:0032869 12133 185 66 3 276 3 2 false 0.2995355009953646 0.2995355009953646 1.999097443178639E-75 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 66 1 385 3 3 false 0.2997249160761194 0.2997249160761194 4.6200993055738E-58 regulation_of_lipoprotein_lipase_activity GO:0051004 12133 21 66 1 129 2 2 false 0.3001453488372083 0.3001453488372083 1.3604812775118876E-24 regulation_of_T_cell_activation GO:0050863 12133 186 66 2 339 2 2 false 0.30030894904954314 0.30030894904954314 1.0254523445533855E-100 multi-organism_transport GO:0044766 12133 29 66 1 3441 42 2 false 0.30065487483372577 0.30065487483372577 2.716860412473803E-72 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 66 3 1663 23 2 false 0.30090298088452766 0.30090298088452766 7.181952736648417E-207 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 66 4 129 5 1 false 0.30117488947602206 0.30117488947602206 1.1512773005265922E-37 ATP_binding GO:0005524 12133 1212 66 11 1638 13 3 false 0.30202843108823113 0.30202843108823113 0.0 synaptic_vesicle_membrane GO:0030672 12133 34 66 1 302 3 3 false 0.30203603881096286 0.30203603881096286 9.733838677997728E-46 nucleotide_binding GO:0000166 12133 1997 66 23 2103 23 2 false 0.3024116153414642 0.3024116153414642 1.0169073992212018E-181 regulation_of_body_fluid_levels GO:0050878 12133 527 66 5 4595 32 2 false 0.3024431324459371 0.3024431324459371 0.0 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 66 5 129 5 1 false 0.3026208569859102 0.3026208569859102 2.104544859412626E-28 negative_regulation_of_osteoblast_differentiation GO:0045668 12133 31 66 1 447 5 3 false 0.3030526887185176 0.3030526887185176 1.6516284138914347E-48 ERBB_signaling_pathway GO:0038127 12133 199 66 5 586 11 1 false 0.3034726323915086 0.3034726323915086 2.435227003721618E-162 regulation_of_kidney_development GO:0090183 12133 45 66 1 1017 8 2 false 0.3046457203076786 0.3046457203076786 1.5046595162555353E-79 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 66 2 286 3 3 false 0.3047375160051405 0.3047375160051405 4.516187028693684E-81 activation_of_NF-kappaB-inducing_kinase_activity GO:0007250 12133 16 66 1 319 7 5 false 0.3049236110611775 0.3049236110611775 2.6671768240247182E-27 clathrin-coated_endocytic_vesicle GO:0045334 12133 31 66 1 272 3 2 false 0.30541687769815945 0.30541687769815945 1.6415618681542047E-41 regulation_of_peptide_transport GO:0090087 12133 133 66 2 962 8 2 false 0.30550983889077915 0.30550983889077915 3.702869511284133E-167 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 66 2 220 3 1 false 0.3060084316839271 0.3060084316839271 2.4407604211478482E-62 cerebral_cortex_development GO:0021987 12133 60 66 1 3152 19 3 false 0.3066488534945649 0.3066488534945649 1.7800361131587683E-128 calcium_ion_binding GO:0005509 12133 447 66 4 2699 17 1 false 0.3066937211780085 0.3066937211780085 0.0 origin_recognition_complex GO:0000808 12133 37 66 1 3160 31 2 false 0.3071011082422323 0.3071011082422323 5.523329685243896E-87 MCM_complex GO:0042555 12133 36 66 1 2976 30 2 false 0.30713346429692917 0.30713346429692917 4.093123828825495E-84 MCM_core_complex GO:0097373 12133 36 66 1 2976 30 1 false 0.30713346429692917 0.30713346429692917 4.093123828825495E-84 signalosome GO:0008180 12133 32 66 1 4399 50 2 false 0.30726271242029535 0.30726271242029535 7.6195658646057E-82 positive_regulation_of_cell_migration GO:0030335 12133 206 66 3 736 7 3 false 0.307346926142342 0.307346926142342 9.676188091528093E-189 positive_regulation_of_DNA_repair GO:0045739 12133 26 66 1 440 6 4 false 0.30761427564784194 0.30761427564784194 1.5959457492821637E-42 chaperone-mediated_protein_folding GO:0061077 12133 21 66 1 183 3 1 false 0.3077550110427542 0.3077550110427542 5.187624892128013E-28 positive_regulation_of_pathway-restricted_SMAD_protein_phosphorylation GO:0010862 12133 21 66 1 582 10 4 false 0.30955725527590006 0.30955725527590006 6.361190418260006E-39 negative_regulation_of_translation GO:0017148 12133 61 66 2 1470 27 4 false 0.30959507484054793 0.30959507484054793 1.1152524521517982E-109 sequence-specific_DNA_binding GO:0043565 12133 1189 66 10 2091 15 1 false 0.3098437961960954 0.3098437961960954 0.0 positive_regulation_of_cholesterol_efflux GO:0010875 12133 9 66 1 29 1 3 false 0.3103448275862069 0.3103448275862069 9.985017481269311E-8 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 66 3 527 4 2 false 0.31036053130946234 0.31036053130946234 6.55805140577772E-158 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 66 4 522 12 3 false 0.3118862873526903 0.3118862873526903 1.2617392241842968E-123 calcium_ion-dependent_exocytosis GO:0017156 12133 42 66 1 246 2 1 false 0.31289198606274066 0.31289198606274066 2.197566782820825E-48 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 66 3 1384 14 2 false 0.314526417609524 0.314526417609524 1.3395090025049634E-243 telomere_organization GO:0032200 12133 62 66 1 689 4 1 false 0.31479903148566624 0.31479903148566624 5.719891778584196E-90 regulation_of_sodium_ion_transport GO:0002028 12133 37 66 1 215 2 2 false 0.31523581830034664 0.31523581830034664 1.8499074186131244E-42 protein_localization GO:0008104 12133 1434 66 25 1642 27 1 false 0.3152968190354031 0.3152968190354031 3.426309620265761E-270 response_to_metal_ion GO:0010038 12133 189 66 3 277 3 1 false 0.3160382985403261 0.3160382985403261 1.2236423246824455E-74 clathrin_vesicle_coat GO:0030125 12133 20 66 1 116 2 3 false 0.3163418290854621 0.3163418290854621 7.110456703810784E-23 metal_ion_transport GO:0030001 12133 455 66 4 606 4 1 false 0.3167536563698815 0.3167536563698815 4.665536224038032E-147 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 66 5 1379 9 2 false 0.316982238185212 0.316982238185212 0.0 intracellular_organelle_lumen GO:0070013 12133 2919 66 33 5320 56 2 false 0.31742090645649584 0.31742090645649584 0.0 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 66 3 362 9 4 false 0.31761298780347724 0.31761298780347724 1.827388630734988E-82 regulation_of_lymphocyte_activation GO:0051249 12133 245 66 2 434 2 2 false 0.3181107055055677 0.3181107055055677 2.1869753110099554E-128 mitogen-activated_protein_kinase_kinase_kinase_binding GO:0031435 12133 18 66 1 341 7 1 false 0.31824741991785926 0.31824741991785926 2.6004179619646645E-30 biological_regulation GO:0065007 12133 6908 66 46 10446 66 1 false 0.31830583803561735 0.31830583803561735 0.0 positive_regulation_of_cytokine_production GO:0001819 12133 175 66 3 614 7 3 false 0.3186816026400123 0.3186816026400123 1.2195240299259301E-158 coated_vesicle GO:0030135 12133 202 66 2 712 4 1 false 0.31950765315452473 0.31950765315452473 1.1363731817938802E-183 detection_of_chemical_stimulus GO:0009593 12133 42 66 1 2431 22 2 false 0.31961247240221435 0.31961247240221435 1.257213734086061E-91 regulation_of_sterol_transport GO:0032371 12133 25 66 1 78 1 2 false 0.3205128205128135 0.3205128205128135 5.8554367810462755E-21 organelle_lumen GO:0043233 12133 2968 66 33 5401 56 2 false 0.3220033540583598 0.3220033540583598 0.0 pathway-restricted_SMAD_protein_phosphorylation GO:0060389 12133 30 66 1 1331 17 2 false 0.32289628646970403 0.32289628646970403 6.939301694879332E-62 limbic_system_development GO:0021761 12133 61 66 1 2686 17 2 false 0.32409919020993483 0.32409919020993483 6.732470891549266E-126 negative_regulation_of_cell_communication GO:0010648 12133 599 66 6 4860 38 3 false 0.32437842376711434 0.32437842376711434 0.0 basal_transcription_machinery_binding GO:0001098 12133 464 66 5 6397 52 1 false 0.3246286139447525 0.3246286139447525 0.0 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 66 2 207 3 2 false 0.32496096256869944 0.32496096256869944 2.976076769798144E-59 fatty_acid_biosynthetic_process GO:0006633 12133 86 66 1 482 2 3 false 0.32531637925832146 0.32531637925832146 1.4111993524131067E-97 activation_of_innate_immune_response GO:0002218 12133 155 66 5 362 9 2 false 0.326191159359801 0.326191159359801 1.0665156090103768E-106 regulation_of_lipase_activity GO:0060191 12133 127 66 2 877 8 2 false 0.32639107218668884 0.32639107218668884 7.685839486208197E-157 adenyl_ribonucleotide_binding GO:0032559 12133 1231 66 11 1645 13 2 false 0.3266439694398237 0.3266439694398237 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 66 11 1650 13 1 false 0.3271165438265963 0.3271165438265963 0.0 response_to_insulin_stimulus GO:0032868 12133 216 66 3 313 3 1 false 0.3272251412333277 0.3272251412333277 1.4650294580642456E-83 SCF_ubiquitin_ligase_complex GO:0019005 12133 26 66 2 90 4 1 false 0.32739248353351547 0.32739248353351547 3.4442933577123775E-23 cytoplasmic_microtubule GO:0005881 12133 41 66 1 5210 50 2 false 0.32760371952705514 0.32760371952705514 1.5944596258703277E-103 positive_regulation_of_endothelial_cell_migration GO:0010595 12133 45 66 2 117 3 3 false 0.3285664859877755 0.3285664859877755 1.8451178464107226E-33 glomerular_epithelium_development GO:0072010 12133 14 66 1 78 2 2 false 0.3286713286713216 0.3286713286713216 9.768201397951623E-16 regulation_of_pathway-restricted_SMAD_protein_phosphorylation GO:0060393 12133 26 66 1 867 13 3 false 0.32875689046559226 0.32875689046559226 2.407355620871874E-50 regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900739 12133 24 66 1 315 5 3 false 0.3289363855756261 0.3289363855756261 1.6734366655590734E-36 neurotransmitter_secretion GO:0007269 12133 76 66 1 611 3 4 false 0.3291368915174876 0.3291368915174876 4.47779868450661E-99 negative_regulation_of_viral_reproduction GO:0048525 12133 28 66 1 2903 41 4 false 0.32978009484333604 0.32978009484333604 3.8119989558045655E-68 monocarboxylic_acid_biosynthetic_process GO:0072330 12133 120 66 1 363 1 2 false 0.3305785123966957 0.3305785123966957 2.0410344299018427E-99 p53_binding GO:0002039 12133 49 66 1 6397 52 1 false 0.3306537186821842 0.3306537186821842 2.351284918255247E-124 regulation_of_sequestering_of_calcium_ion GO:0051282 12133 56 66 1 6326 45 4 false 0.33070745023376463 0.33070745023376463 1.2435674094173866E-138 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 66 1 242 2 2 false 0.3311957751791627 0.3311957751791627 2.220259827778367E-49 negative_regulation_of_epithelial_cell_migration GO:0010633 12133 26 66 1 208 3 3 false 0.33146897425076083 0.33146897425076083 1.1069382135780033E-33 kinesin_complex GO:0005871 12133 20 66 1 110 2 1 false 0.33194328607172413 0.33194328607172413 2.27584542759169E-22 protein_destabilization GO:0031648 12133 18 66 1 99 2 1 false 0.33209647495360395 0.33209647495360395 3.976949780666304E-20 cell_development GO:0048468 12133 1255 66 9 3306 20 4 false 0.33235025469303775 0.33235025469303775 0.0 anion_binding GO:0043168 12133 2280 66 16 4448 28 1 false 0.332575679085081 0.332575679085081 0.0 regulation_of_binding GO:0051098 12133 172 66 2 9142 63 2 false 0.3328938767372629 0.3328938767372629 0.0 phospholipase_C_activity GO:0004629 12133 107 66 2 185 2 2 false 0.3331962397179737 0.3331962397179737 3.369173077902444E-54 histone_H4_deacetylation GO:0070933 12133 16 66 1 48 1 1 false 0.33333333333333176 0.33333333333333176 4.4348869405293416E-13 extrinsic_to_plasma_membrane GO:0019897 12133 76 66 1 1352 7 2 false 0.3336310278165589 0.3336310278165589 1.795634708335668E-126 autophagy GO:0006914 12133 112 66 3 1972 36 1 false 0.3356447644869265 0.3356447644869265 4.585569427927113E-186 negative_regulation_of_muscle_cell_differentiation GO:0051148 12133 33 66 1 584 7 3 false 0.3359072362898429 0.3359072362898429 1.1148204606376211E-54 negative_regulation_of_apoptotic_signaling_pathway GO:2001234 12133 25 66 1 812 13 3 false 0.33609805689323596 0.33609805689323596 4.1099554708767054E-48 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 66 5 305 8 2 false 0.3364126112628215 0.3364126112628215 3.640759676212702E-91 nucleoplasm GO:0005654 12133 1443 66 20 2767 35 2 false 0.33653332220646714 0.33653332220646714 0.0 vasculogenesis GO:0001570 12133 62 66 1 3056 20 4 false 0.3371620550063283 0.3371620550063283 4.885889713794216E-131 positive_regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902110 12133 37 66 1 1374 15 3 false 0.3374097202597118 0.3374097202597118 1.7604614397711276E-73 blood_coagulation GO:0007596 12133 443 66 5 550 5 3 false 0.33750966997775433 0.33750966997775433 4.662213706291943E-117 regulation_of_mitochondrial_membrane_permeability GO:0046902 12133 46 66 1 2152 19 3 false 0.3378631877683498 0.3378631877683498 4.367031159968052E-96 angiogenesis GO:0001525 12133 300 66 3 2776 19 3 false 0.33825760993495513 0.33825760993495513 0.0 locomotion GO:0040011 12133 1045 66 8 10446 66 1 false 0.3387336139517714 0.3387336139517714 0.0 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 66 1 953 11 4 false 0.3388731956982478 0.3388731956982478 1.0482452124052062E-64 regulation_of_phospholipase_activity GO:0010517 12133 105 66 2 180 2 2 false 0.33891992551207495 0.33891992551207495 1.3354430203572309E-52 regulation_of_heart_rate GO:0002027 12133 45 66 1 2097 19 2 false 0.3389743539617051 0.3389743539617051 6.492024002196435E-94 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 66 3 140 3 1 false 0.3398185799186785 0.3398185799186785 9.838676628741767E-37 negative_regulation_of_signaling GO:0023057 12133 597 66 6 4884 39 3 false 0.3400038751432207 0.3400038751432207 0.0 negative_regulation_of_signal_transduction GO:0009968 12133 571 66 6 3588 30 5 false 0.3401609033101707 0.3401609033101707 0.0 phosphatidylinositol_phospholipase_C_activity GO:0004435 12133 20 66 1 107 2 1 false 0.34032798448246915 0.34032798448246915 4.180907049564432E-22 negative_regulation_of_cell_cycle GO:0045786 12133 298 66 4 3131 31 3 false 0.3407486035313757 0.3407486035313757 0.0 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 66 4 129 5 1 false 0.3410139321247776 0.3410139321247776 3.5310664374642874E-37 cellular_response_to_stress GO:0033554 12133 1124 66 10 4743 36 2 false 0.3410323650790479 0.3410323650790479 0.0 regulation_of_cardiac_muscle_contraction GO:0055117 12133 44 66 1 129 1 3 false 0.34108527131783234 0.34108527131783234 1.5054018361547051E-35 regulation_of_intracellular_transport GO:0032386 12133 276 66 6 1731 30 3 false 0.3415647438416053 0.3415647438416053 0.0 secretory_granule_membrane GO:0030667 12133 44 66 1 445 4 2 false 0.3415976761815982 0.3415976761815982 7.1063433971197205E-62 catalytic_activity GO:0003824 12133 4901 66 33 10478 66 2 false 0.34276274907416965 0.34276274907416965 0.0 cellular_response_to_retinoic_acid GO:0071300 12133 43 66 1 638 6 3 false 0.34319661339345914 0.34319661339345914 6.348384463366899E-68 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 66 3 1130 13 2 false 0.343405009703694 0.343405009703694 1.9819409219356823E-214 cation_transmembrane_transporter_activity GO:0008324 12133 365 66 3 701 4 2 false 0.3436617866671123 0.3436617866671123 5.744660517109641E-210 regulation_of_ossification GO:0030278 12133 137 66 2 1586 14 2 false 0.34423027801412065 0.34423027801412065 7.69235263015688E-202 vesicle_coat GO:0030120 12133 38 66 1 381 4 3 false 0.34428677945603126 0.34428677945603126 2.9673810590707202E-53 nucleotide_catabolic_process GO:0009166 12133 969 66 10 1318 12 2 false 0.3452450670576118 0.3452450670576118 0.0 regulation_of_Notch_signaling_pathway GO:0008593 12133 30 66 1 1655 23 2 false 0.34530888893538725 0.34530888893538725 9.430926954379174E-65 regulation_of_cell-matrix_adhesion GO:0001952 12133 57 66 1 165 1 2 false 0.345454545454564 0.345454545454564 9.897591552333977E-46 protein_phosphorylation GO:0006468 12133 1195 66 15 2577 29 2 false 0.3457400537725267 0.3457400537725267 0.0 focal_adhesion_assembly GO:0048041 12133 45 66 1 130 1 2 false 0.3461538461538416 0.3461538461538416 5.211006355919991E-36 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 66 1 230 2 4 false 0.3466869185493838 0.3466869185493838 2.6271911283291635E-48 regulation_of_lipid_transport GO:0032368 12133 53 66 1 1026 8 2 false 0.34675665490712626 0.34675665490712626 4.3014798118534845E-90 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 66 2 227 4 2 false 0.3471208492753596 0.3471208492753596 1.1311225924750782E-59 lipopolysaccharide-mediated_signaling_pathway GO:0031663 12133 40 66 1 1999 21 2 false 0.3472957760753893 0.3472957760753893 1.1212958284897253E-84 mRNA_binding GO:0003729 12133 91 66 4 763 25 1 false 0.34751674741898697 0.34751674741898697 1.7788235024198917E-120 channel_regulator_activity GO:0016247 12133 66 66 1 10257 66 2 false 0.3478091139555068 0.3478091139555068 1.2576121117294417E-172 muscle_tissue_development GO:0060537 12133 295 66 3 1132 8 1 false 0.3478407284099476 0.3478407284099476 3.412889797328503E-281 cellular_macromolecular_complex_assembly GO:0034622 12133 517 66 7 973 11 1 false 0.34835653267536637 0.34835653267536637 3.312522477266262E-291 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 66 2 722 7 3 false 0.34845577364032176 0.34845577364032176 8.18717732691146E-144 regulation_of_actin_cytoskeleton_organization GO:0032956 12133 166 66 1 476 1 3 false 0.3487394957983636 0.3487394957983636 5.437988564533384E-133 phagocytosis GO:0006909 12133 149 66 3 2417 34 2 false 0.35010003134300327 0.35010003134300327 3.130675140672653E-242 regulation_of_activin_receptor_signaling_pathway GO:0032925 12133 19 66 1 143 3 2 false 0.3501050941866002 0.3501050941866002 4.753428687059348E-24 myeloid_cell_homeostasis GO:0002262 12133 111 66 2 1628 18 2 false 0.3503477536876075 0.3503477536876075 2.626378318706563E-175 dicarboxylic_acid_transport GO:0006835 12133 48 66 1 137 1 1 false 0.3503649635036604 0.3503649635036604 4.0880293232800326E-38 macromolecule_modification GO:0043412 12133 2461 66 28 6052 64 1 false 0.35062815046011164 0.35062815046011164 0.0 release_of_sequestered_calcium_ion_into_cytosol_by_sarcoplasmic_reticulum GO:0014808 12133 20 66 1 57 1 2 false 0.35087719298245373 0.35087719298245373 8.262622213776067E-16 regulation_of_metal_ion_transport GO:0010959 12133 159 66 2 527 4 2 false 0.3511533061761293 0.3511533061761293 1.9143009234930405E-139 Ras_protein_signal_transduction GO:0007265 12133 365 66 5 547 6 1 false 0.35116301959983054 0.35116301959983054 2.1494674666292624E-150 regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902108 12133 39 66 1 1375 15 3 false 0.35199058094737495 0.35199058094737495 1.4191902379759833E-76 mammary_gland_epithelium_development GO:0061180 12133 68 66 1 661 4 2 false 0.3529181933447077 0.3529181933447077 1.483146375538298E-94 steroid_hormone_receptor_binding GO:0035258 12133 62 66 2 104 2 1 false 0.3530619865571091 0.3530619865571091 4.2931773052216616E-30 mammary_gland_duct_morphogenesis GO:0060603 12133 37 66 1 274 3 3 false 0.35397980079166086 0.35397980079166086 1.1164930078248282E-46 histone_H3_deacetylation GO:0070932 12133 17 66 1 48 1 1 false 0.3541666666666646 0.3541666666666646 2.356033687156231E-13 regulation_of_protein_ubiquitination GO:0031396 12133 176 66 4 1344 23 2 false 0.3550105722778631 0.3550105722778631 8.0617715234352E-226 regulation_of_transmembrane_transport GO:0034762 12133 183 66 2 6614 45 3 false 0.3550946989941634 0.3550946989941634 0.0 renal_system_development GO:0072001 12133 196 66 2 2686 17 2 false 0.35534733209963365 0.35534733209963365 5.871867151923005E-304 nuclear_envelope_organization GO:0006998 12133 27 66 1 819 13 2 false 0.3553680492726495 0.3553680492726495 3.6853965573892743E-51 extracellular_membrane-bounded_organelle GO:0065010 12133 59 66 1 7284 54 2 false 0.35647237908784135 0.35647237908784135 2.3146567535480854E-148 fatty_acid_derivative_metabolic_process GO:1901568 12133 52 66 1 7599 64 2 false 0.3567976557996101 0.3567976557996101 1.5249934864539741E-134 sprouting_angiogenesis GO:0002040 12133 41 66 1 300 3 1 false 0.35754326502213885 0.35754326502213885 1.6101766178150428E-51 NF-kappaB_import_into_nucleus GO:0042348 12133 34 66 2 220 8 2 false 0.3577797663593452 0.3577797663593452 9.912199511410154E-41 regulation_of_bone_remodeling GO:0046850 12133 23 66 1 64 1 2 false 0.359374999999996 0.359374999999996 6.8156370641429495E-18 proteasome_complex GO:0000502 12133 62 66 1 9248 66 2 false 0.35951965437585576 0.35951965437585576 4.919625587422917E-161 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 66 2 2180 24 2 false 0.3599942650277588 0.3599942650277588 1.341003616993524E-193 thiolester_hydrolase_activity GO:0016790 12133 86 66 1 814 4 1 false 0.3607826070598034 0.3607826070598034 1.2381238582222513E-118 positive_regulation_of_cell_motility GO:2000147 12133 210 66 3 790 8 4 false 0.361008620244153 0.361008620244153 6.640105808226973E-198 extracellular_organelle GO:0043230 12133 59 66 1 8358 63 2 false 0.3610763363351761 0.3610763363351761 6.7158083402639515E-152 sphingolipid_metabolic_process GO:0006665 12133 68 66 1 1861 12 2 false 0.36111836808067554 0.36111836808067554 3.889189985048589E-126 membrane_raft GO:0045121 12133 163 66 1 2995 8 1 false 0.36124062637888815 0.36124062637888815 3.9757527534590165E-274 protein_insertion_into_mitochondrial_membrane GO:0051204 12133 25 66 1 1644 29 4 false 0.3612508595820981 0.3612508595820981 7.460154269678152E-56 ion_transmembrane_transport GO:0034220 12133 556 66 5 970 7 2 false 0.3623868708839124 0.3623868708839124 1.3121997139332702E-286 regulation_of_calcium_ion_transmembrane_transporter_activity GO:1901019 12133 30 66 1 216 3 3 false 0.3629162742398954 0.3629162742398954 2.0297779433313095E-37 cellular_chemical_homeostasis GO:0055082 12133 525 66 3 734 3 2 false 0.36532648948278423 0.36532648948278423 1.1478565010718528E-189 negative_regulation_of_immune_effector_process GO:0002698 12133 45 66 1 518 5 3 false 0.3663427698029643 0.3663427698029643 6.135357945972138E-66 calcium_channel_complex GO:0034704 12133 33 66 1 90 1 1 false 0.36666666666667436 0.36666666666667436 2.368609630546903E-25 positive_regulation_of_neuron_projection_development GO:0010976 12133 52 66 1 595 5 3 false 0.3680079509356987 0.3680079509356987 4.2542358818193915E-76 post-Golgi_vesicle-mediated_transport GO:0006892 12133 70 66 2 170 3 1 false 0.36825617821090556 0.36825617821090556 1.5403758302393128E-49 PcG_protein_complex GO:0031519 12133 40 66 1 4399 50 2 false 0.36827635843779155 0.36827635843779155 1.797728838055178E-98 regulation_of_extrinsic_apoptotic_signaling_pathway GO:2001236 12133 43 66 2 138 4 2 false 0.3683652663435061 0.3683652663435061 9.021503775464772E-37 microtubule_cytoskeleton_organization GO:0000226 12133 259 66 2 831 4 2 false 0.3688711311510714 0.3688711311510714 4.0880234187670296E-223 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 66 4 129 5 1 false 0.36891259232132473 0.36891259232132473 8.751505837166389E-37 response_to_calcium_ion GO:0051592 12133 78 66 2 189 3 1 false 0.3696982339034692 0.3696982339034692 3.918456545099658E-55 regulation_of_focal_adhesion_assembly GO:0051893 12133 27 66 1 73 1 3 false 0.36986301369863217 0.36986301369863217 1.3403979125160586E-20 regulation_of_peptidase_activity GO:0052547 12133 276 66 3 1151 9 2 false 0.3706273366430498 0.3706273366430498 1.6233323078676786E-274 prostate_gland_development GO:0030850 12133 45 66 1 508 5 3 false 0.37230263409792924 0.37230263409792924 1.535189924421617E-65 epithelial_tube_morphogenesis GO:0060562 12133 245 66 3 340 3 2 false 0.3728780929557253 0.3728780929557253 6.979413529141176E-87 regulation_of_oxidoreductase_activity GO:0051341 12133 60 66 1 2095 16 2 false 0.37288232398267074 0.37288232398267074 1.0461136400990825E-117 protein_autophosphorylation GO:0046777 12133 173 66 3 1195 15 1 false 0.3729377091381416 0.3729377091381416 7.421869914925723E-214 extrinsic_apoptotic_signaling_pathway_in_absence_of_ligand GO:0097192 12133 11 66 1 77 3 2 false 0.3744360902255559 0.3744360902255559 1.4966279999004742E-13 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 66 2 217 2 2 false 0.37455197132611834 0.37455197132611834 2.2668758893633536E-62 histone_ubiquitination GO:0016574 12133 31 66 1 813 12 2 false 0.3748513893507633 0.3748513893507633 8.990376944152675E-57 positive_regulation_of_phospholipase_activity GO:0010518 12133 100 66 2 163 2 3 false 0.37491479209266454 0.37491479209266454 9.231150730946075E-47 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 66 3 389 9 3 false 0.3756633143008548 0.3756633143008548 8.074632425282073E-93 protein_oligomerization GO:0051259 12133 288 66 4 743 8 1 false 0.3768800473504669 0.3768800473504669 1.196705520432063E-214 cytoplasmic_vesicle GO:0031410 12133 764 66 7 8540 66 3 false 0.3773767300025147 0.3773767300025147 0.0 cellular_component_organization GO:0016043 12133 3745 66 39 3839 39 1 false 0.3784393277463262 0.3784393277463262 4.153510440731863E-191 Rac_protein_signal_transduction GO:0016601 12133 33 66 1 365 5 1 false 0.3790836248678643 0.3790836248678643 1.0734561739608448E-47 histone_deacetylase_activity_(H3-K14_specific) GO:0031078 12133 11 66 1 29 1 2 false 0.37931034482758536 0.37931034482758536 2.890399797209533E-8 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 66 1 591 6 3 false 0.3795359900904546 0.3795359900904546 1.267222544612779E-68 muscle_organ_development GO:0007517 12133 308 66 3 1966 14 2 false 0.37953847149435105 0.37953847149435105 0.0 small_conjugating_protein_ligase_binding GO:0044389 12133 147 66 3 1005 15 1 false 0.3795558384357177 0.3795558384357177 6.302468729220369E-181 negative_regulation_of_protein_modification_process GO:0031400 12133 328 66 5 2431 30 3 false 0.3807311282694829 0.3807311282694829 0.0 carboxylic_ester_hydrolase_activity GO:0052689 12133 92 66 1 814 4 1 false 0.38163910774601983 0.38163910774601983 4.359236908507715E-124 organ_development GO:0048513 12133 1929 66 13 3099 19 2 false 0.38191388828630124 0.38191388828630124 0.0 negative_regulation_of_cytokine_production GO:0001818 12133 114 66 2 529 6 3 false 0.3828676608025532 0.3828676608025532 4.407958658606205E-119 molecular_transducer_activity GO:0060089 12133 1070 66 8 10257 66 1 false 0.3829301785601573 0.3829301785601573 0.0 membrane_lipid_metabolic_process GO:0006643 12133 90 66 1 606 3 1 false 0.38318473629436844 0.38318473629436844 5.920711661089953E-110 calcium_ion_transmembrane_transporter_activity GO:0015085 12133 117 66 2 277 3 3 false 0.3840955465818572 0.3840955465818572 2.4235660306174516E-81 sarcoplasmic_reticulum_calcium_ion_transport GO:0070296 12133 21 66 1 1279 29 2 false 0.3846015318459949 0.3846015318459949 3.4336314603626656E-46 phosphoric_ester_hydrolase_activity GO:0042578 12133 446 66 3 814 4 1 false 0.3872173283569549 0.3872173283569549 1.3758870371320904E-242 tissue_development GO:0009888 12133 1132 66 8 3099 19 1 false 0.387274662114111 0.387274662114111 0.0 outer_membrane GO:0019867 12133 112 66 1 4398 19 1 false 0.3880733354207172 0.3880733354207172 7.412183245910406E-226 regulation_of_reproductive_process GO:2000241 12133 171 66 2 6891 54 2 false 0.38921803321323817 0.38921803321323817 0.0 glycogen_catabolic_process GO:0005980 12133 23 66 1 59 1 3 false 0.38983050847457373 0.38983050847457373 6.934353518851451E-17 regulation_of_endopeptidase_activity GO:0052548 12133 264 66 3 480 4 2 false 0.3903826094237537 0.3903826094237537 9.691263405564588E-143 response_to_oxygen_levels GO:0070482 12133 214 66 3 676 7 1 false 0.39059565366210136 0.39059565366210136 1.6255941364061853E-182 cell_cycle_arrest GO:0007050 12133 202 66 3 998 11 2 false 0.3906251651652891 0.3906251651652891 1.5077994882682823E-217 lymphocyte_migration GO:0072676 12133 26 66 1 224 4 1 false 0.3916913814368139 0.3916913814368139 1.4277656298732434E-34 in_utero_embryonic_development GO:0001701 12133 295 66 2 471 2 1 false 0.3917875050820852 0.3917875050820852 1.719393530200133E-134 hormone_receptor_binding GO:0051427 12133 122 66 2 918 10 1 false 0.39188013980944975 0.39188013980944975 1.5301276126382055E-155 regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043516 12133 24 66 1 158 3 3 false 0.3920763586973361 0.3920763586973361 6.672081748801047E-29 egress_of_virus_within_host_cell GO:0046788 12133 11 66 1 28 1 2 false 0.3928571428571428 0.3928571428571428 4.656755228837597E-8 tube_development GO:0035295 12133 371 66 3 3304 20 2 false 0.39338340781821884 0.39338340781821884 0.0 prostanoid_metabolic_process GO:0006692 12133 24 66 1 61 1 2 false 0.39344262295082544 0.39344262295082544 1.6824333127705597E-17 alcohol_metabolic_process GO:0006066 12133 218 66 2 2438 15 2 false 0.39353934478782926 0.39353934478782926 4.437115E-318 syntaxin-1_binding GO:0017075 12133 13 66 1 33 1 1 false 0.39393939393939115 0.39393939393939115 1.7446939147379062E-9 histone_deacetylase_activity GO:0004407 12133 26 66 1 66 1 3 false 0.39393939393939675 0.39393939393939675 6.044910921634578E-19 U5_snRNP GO:0005682 12133 80 66 6 93 6 1 false 0.39423021363547917 0.39423021363547917 3.852654648545616E-16 striated_muscle_contraction GO:0006941 12133 87 66 1 220 1 1 false 0.39545454545453296 0.39545454545453296 1.3725907999420383E-63 regulation_of_cell_adhesion_mediated_by_integrin GO:0033628 12133 38 66 1 247 3 2 false 0.3955201592832577 0.3955201592832577 1.2586020394178986E-45 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 66 2 254 4 3 false 0.3956712708202845 0.3956712708202845 3.7262148804586973E-69 regulation_of_protein_phosphorylation GO:0001932 12133 787 66 12 1444 20 3 false 0.3959640630990555 0.3959640630990555 0.0 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 66 1 162 2 5 false 0.39613526570044455 0.39613526570044455 7.1760328941400225E-37 snRNA_binding GO:0017069 12133 15 66 1 763 25 1 false 0.3961538238292561 0.3961538238292561 8.685184804619145E-32 cytoplasmic_sequestering_of_protein GO:0051220 12133 24 66 1 156 3 2 false 0.3963133640552898 0.3963133640552898 9.286705188012584E-29 negative_regulation_of_binding GO:0051100 12133 72 66 1 9054 63 3 false 0.3963337616507552 0.3963337616507552 1.0408990583833388E-181 regulation_of_alternative_mRNA_splicing,_via_spliceosome GO:0000381 12133 16 66 2 37 3 2 false 0.3963963963963978 0.3963963963963978 7.76652299088412E-11 negative_regulation_of_myeloid_cell_differentiation GO:0045638 12133 52 66 1 543 5 3 false 0.396668072423952 0.396668072423952 6.206039090414828E-74 spindle_checkpoint GO:0031577 12133 45 66 1 202 2 1 false 0.3967784838184953 0.3967784838184953 4.3818533729449334E-46 ovulation_cycle_process GO:0022602 12133 71 66 1 8057 57 3 false 0.3972735484472653 0.3972735484472653 5.317350826514013E-176 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 66 9 2771 30 5 false 0.3973627174573453 0.3973627174573453 0.0 poly(A)_RNA_binding GO:0008143 12133 11 66 1 94 4 2 false 0.39740305053187397 0.39740305053187397 1.4483869139240058E-14 calcium_channel_activity GO:0005262 12133 104 66 2 241 3 3 false 0.3975225264327794 0.3975225264327794 5.2662088963328235E-71 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 66 4 129 5 1 false 0.397810578910211 0.397810578910211 2.4714073881998435E-36 protein_import_into_nucleus,_translocation GO:0000060 12133 35 66 1 2378 34 3 false 0.39812019228577206 0.39812019228577206 9.036748006294301E-79 DNA_polymerase_activity GO:0034061 12133 49 66 1 123 1 1 false 0.3983739837398253 0.3983739837398253 1.6565752525035403E-35 cell_aging GO:0007569 12133 68 66 1 7548 56 2 false 0.3986960726023874 0.3986960726023874 6.81322307999876E-168 tyrosine_phosphorylation_of_STAT_protein GO:0007260 12133 51 66 1 227 2 2 false 0.39963354255195205 0.39963354255195205 4.751307982054789E-52 regulation_of_vesicle-mediated_transport GO:0060627 12133 196 66 2 6585 46 3 false 0.3998343606725878 0.3998343606725878 0.0 T_cell_differentiation_in_thymus GO:0033077 12133 56 66 1 140 1 1 false 0.3999999999999826 0.3999999999999826 1.7504218329707695E-40 positive_regulation_of_adenylate_cyclase_activity GO:0045762 12133 52 66 1 130 1 5 false 0.3999999999999939 0.3999999999999939 1.4124265749856537E-37 histone_deacetylase_activity_(H4-K16_specific) GO:0034739 12133 12 66 1 30 1 2 false 0.39999999999999963 0.39999999999999963 1.1561599188838122E-8 negative_regulation_of_ryanodine-sensitive_calcium-release_channel_activity GO:0060315 12133 10 66 1 25 1 4 false 0.400000000000001 0.400000000000001 3.059264063436909E-7 negative_regulation_of_transferase_activity GO:0051348 12133 180 66 2 2118 16 3 false 0.400096689141034 0.400096689141034 1.0892582554699503E-266 identical_protein_binding GO:0042802 12133 743 66 7 6397 52 1 false 0.40022391787880207 0.40022391787880207 0.0 metanephric_glomerulus_development GO:0072224 12133 15 66 1 67 2 2 false 0.40027137042063277 0.40027137042063277 2.892004811076329E-15 NF-kappaB-inducing_kinase_activity GO:0004704 12133 21 66 1 301 7 2 false 0.4004384699253998 0.4004384699253998 9.301787616944151E-33 regulation_of_ion_transmembrane_transport GO:0034765 12133 176 66 2 662 5 3 false 0.400715679402058 0.400715679402058 9.171243521861199E-166 stem_cell_development GO:0048864 12133 191 66 2 1273 9 2 false 0.40092970972865716 0.40092970972865716 5.877761968359015E-233 transferrin_transport GO:0033572 12133 24 66 1 1099 23 2 false 0.4013342951771935 0.4013342951771935 8.291143924248354E-50 ovulation_cycle GO:0042698 12133 77 66 1 640 4 3 false 0.4019263681113353 0.4019263681113353 1.431548427183746E-101 cardiovascular_system_development GO:0072358 12133 655 66 5 2686 17 2 false 0.4025380590511207 0.4025380590511207 0.0 circulatory_system_development GO:0072359 12133 655 66 5 2686 17 1 false 0.4025380590511207 0.4025380590511207 0.0 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 66 1 705 9 3 false 0.4026119550166585 0.4026119550166585 4.9570646354646075E-65 DNA_repair GO:0006281 12133 368 66 5 977 11 2 false 0.40275477516071545 0.40275477516071545 3.284245924949814E-280 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 66 37 6638 64 2 false 0.40293862874687025 0.40293862874687025 0.0 interaction_with_host GO:0051701 12133 387 66 12 417 12 2 false 0.40314980498956515 0.40314980498956515 1.9217516081652173E-46 inactivation_of_MAPK_activity GO:0000188 12133 25 66 1 62 1 1 false 0.4032258064516162 0.4032258064516162 6.784005293429779E-18 Rac_GTPase_binding GO:0048365 12133 21 66 1 52 1 1 false 0.4038461538461552 0.4038461538461552 5.208555404055776E-15 coated_vesicle_membrane GO:0030662 12133 122 66 2 368 4 2 false 0.40417247518224836 0.40417247518224836 6.74679218492705E-101 negative_regulation_of_cell_differentiation GO:0045596 12133 381 66 4 3552 30 4 false 0.40417766806858935 0.40417766806858935 0.0 activin_receptor_signaling_pathway GO:0032924 12133 28 66 1 232 4 1 false 0.40432366190849006 0.40432366190849006 9.723452082207629E-37 RNA_export_from_nucleus GO:0006405 12133 72 66 2 165 3 2 false 0.4044835607307819 0.4044835607307819 1.3059643179360761E-48 negative_regulation_of_immune_response GO:0050777 12133 48 66 1 1512 16 4 false 0.4047621149998941 0.4047621149998941 6.35137019676024E-92 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 66 3 442 4 3 false 0.4048741468010038 0.4048741468010038 4.945935388068452E-131 protein_phosphatase_regulator_activity GO:0019888 12133 49 66 1 214 2 2 false 0.4063446097143487 0.4063446097143487 1.5290549326601881E-49 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 66 4 2896 19 3 false 0.40645832247997266 0.40645832247997266 0.0 membrane_coat GO:0030117 12133 66 66 1 7525 59 4 false 0.4065368778485562 0.4065368778485562 1.024710613883824E-163 glucan_catabolic_process GO:0009251 12133 24 66 1 59 1 2 false 0.40677966101694785 0.40677966101694785 4.622902345900986E-17 regulation_of_extrinsic_apoptotic_signaling_pathway_in_absence_of_ligand GO:2001239 12133 10 66 1 44 2 2 false 0.40697674418604607 0.40697674418604607 4.030215690961509E-10 nucleolus GO:0005730 12133 1357 66 18 4208 52 3 false 0.4073356858515877 0.4073356858515877 0.0 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 66 14 2643 25 1 false 0.40756817740505097 0.40756817740505097 0.0 tubulin_binding GO:0015631 12133 150 66 2 556 5 1 false 0.4090126313646061 0.4090126313646061 4.293395323631497E-140 endosome_membrane GO:0010008 12133 248 66 2 1627 9 2 false 0.40914288817471256 0.40914288817471256 8.244139595488818E-301 regulation_of_muscle_contraction GO:0006937 12133 96 66 1 234 1 2 false 0.4102564102564057 0.4102564102564057 3.0261009246098835E-68 negative_regulation_of_ion_transport GO:0043271 12133 50 66 1 974 10 3 false 0.4111060774382985 0.4111060774382985 4.081641839466338E-85 protein_K48-linked_ubiquitination GO:0070936 12133 37 66 2 163 6 1 false 0.41175449597732694 0.41175449597732694 1.6289154422281443E-37 regulation_of_cholesterol_efflux GO:0010874 12133 14 66 1 34 1 2 false 0.41176470588235115 0.41176470588235115 7.184033766567843E-10 leading_edge_membrane GO:0031256 12133 93 66 1 1450 8 2 false 0.41235105959874185 0.41235105959874185 2.320023810279922E-149 regulation_of_striated_muscle_contraction GO:0006942 12133 52 66 1 126 1 2 false 0.4126984126984203 0.4126984126984203 1.1247408012389437E-36 endopeptidase_activity GO:0004175 12133 470 66 4 586 4 1 false 0.41276089960477036 0.41276089960477036 5.73935751356398E-126 histone_deacetylase_complex GO:0000118 12133 50 66 1 3138 33 2 false 0.4130351030199122 0.4130351030199122 6.6201010514053174E-111 homeostatic_process GO:0042592 12133 990 66 10 2082 19 1 false 0.4139290013880978 0.4139290013880978 0.0 regulation_of_interleukin-2_production GO:0032663 12133 33 66 1 327 5 2 false 0.4145463164219776 0.4145463164219776 4.834102143986747E-46 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 66 3 308 4 2 false 0.41479437117240936 0.41479437117240936 5.66231040699253E-91 response_to_heat GO:0009408 12133 56 66 1 2544 24 2 false 0.4153024177148419 0.4153024177148419 2.557066757112981E-116 regulation_of_NF-kappaB_import_into_nucleus GO:0042345 12133 34 66 2 197 8 3 false 0.4154226750225527 0.4154226750225527 5.91301474468331E-39 cellular_response_to_calcium_ion GO:0071277 12133 28 66 1 119 2 2 false 0.41674975074775955 0.41674975074775955 7.394441943199249E-28 digestive_tract_development GO:0048565 12133 88 66 1 3152 19 3 false 0.41699926079301664 0.41699926079301664 8.415940911182059E-174 regulation_of_apoptotic_process GO:0042981 12133 1019 66 12 1381 15 2 false 0.41750566912513193 0.41750566912513193 0.0 cell_differentiation GO:0030154 12133 2154 66 17 2267 17 1 false 0.41795295253275927 0.41795295253275927 2.602261335719434E-194 circadian_rhythm GO:0007623 12133 66 66 2 148 3 1 false 0.4186846897218709 0.4186846897218709 1.0122432742541851E-43 neuron_migration GO:0001764 12133 89 66 1 1360 8 2 false 0.4189351044380588 0.4189351044380588 4.085890514650152E-142 intra-Golgi_vesicle-mediated_transport GO:0006891 12133 28 66 1 170 3 1 false 0.41924817264180647 0.41924817264180647 1.1323384985599744E-32 wound_healing GO:0042060 12133 543 66 5 905 7 1 false 0.4194205154903551 0.4194205154903551 1.120707554751266E-263 post-embryonic_development GO:0009791 12133 81 66 1 4373 29 3 false 0.41955304335570187 0.41955304335570187 1.5270071764931075E-174 protein_serine/threonine_phosphatase_activity GO:0004722 12133 49 66 1 206 2 1 false 0.4200331517878135 0.4200331517878135 1.2741001335034851E-48 clathrin-coated_endocytic_vesicle_membrane GO:0030669 12133 26 66 1 157 3 3 false 0.42130675981094745 0.42130675981094745 2.9127380680410067E-30 Golgi_vesicle_transport GO:0048193 12133 170 66 3 2599 36 3 false 0.4220966788796779 0.4220966788796779 6.28157499519694E-272 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 66 4 417 5 2 false 0.4226377658783891 0.4226377658783891 7.174398789465976E-117 regulation_of_protein_export_from_nucleus GO:0046825 12133 24 66 1 188 4 3 false 0.4236474558086372 0.4236474558086372 7.565886554812955E-31 interferon-gamma-mediated_signaling_pathway GO:0060333 12133 66 66 2 330 7 2 false 0.42412307492535983 0.42412307492535983 3.5052495329479947E-71 cytoplasmic_vesicle_part GO:0044433 12133 366 66 4 7185 65 3 false 0.4241437075116974 0.4241437075116974 0.0 regulation_of_monooxygenase_activity GO:0032768 12133 42 66 1 99 1 2 false 0.424242424242414 0.424242424242414 6.101240639317122E-29 regulation_of_cell_division GO:0051302 12133 75 66 1 6427 47 2 false 0.4251742529432534 0.4251742529432534 9.599183496643589E-177 oxidoreductase_activity,_acting_on_paired_donors,_with_incorporation_or_reduction_of_molecular_oxygen,_NAD(P)H_as_one_donor,_and_incorporation_of_one_atom_of_oxygen GO:0016709 12133 57 66 1 134 1 2 false 0.4253731343283531 0.4253731343283531 2.9523294110840615E-39 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 66 3 5033 39 3 false 0.4260897251588676 0.4260897251588676 0.0 pallium_development GO:0021543 12133 89 66 1 3099 19 2 false 0.42609233690230086 0.42609233690230086 1.1299570779339424E-174 cellular_response_to_nutrient_levels GO:0031669 12133 110 66 1 258 1 2 false 0.4263565891472961 0.4263565891472961 7.13814980036364E-76 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds GO:0016810 12133 82 66 1 2556 17 1 false 0.42655588054592886 0.42655588054592886 6.720612726716271E-157 protein_phosphorylated_amino_acid_binding GO:0045309 12133 19 66 2 42 3 1 false 0.42700348432056423 0.42700348432056423 2.238261550776809E-12 RNA-directed_DNA_polymerase_activity GO:0003964 12133 21 66 1 49 1 1 false 0.4285714285714328 0.4285714285714328 2.560824792650333E-14 monovalent_inorganic_cation_homeostasis GO:0055067 12133 56 66 1 330 3 1 false 0.42865499834879806 0.42865499834879806 9.24814230107908E-65 negative_regulation_of_sequestering_of_calcium_ion GO:0051283 12133 56 66 1 2733 27 3 false 0.42975497894778714 0.42975497894778714 4.430376378213242E-118 non-membrane_spanning_protein_tyrosine_kinase_activity GO:0004715 12133 44 66 1 180 2 1 false 0.43016759776530655 0.43016759776530655 4.841672635603901E-43 positive_regulation_of_hydrolase_activity GO:0051345 12133 562 66 5 2891 22 3 false 0.4305273328680854 0.4305273328680854 0.0 positive_regulation_of_ryanodine-sensitive_calcium-release_channel_activity GO:0060316 12133 7 66 1 29 2 4 false 0.43103448275862205 0.43103448275862205 6.407052883814491E-7 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 66 3 6813 50 2 false 0.4311681619505563 0.4311681619505563 0.0 regulation_of_release_of_sequestered_calcium_ion_into_cytosol_by_sarcoplasmic_reticulum GO:0010880 12133 16 66 1 37 1 2 false 0.43243243243243207 0.43243243243243207 7.76652299088412E-11 transition_metal_ion_transport GO:0000041 12133 60 66 1 455 4 1 false 0.433150133736984 0.433150133736984 1.613674695371724E-76 phosphatidylinositol_3-kinase_cascade GO:0014065 12133 75 66 1 173 1 1 false 0.4335260115606976 0.4335260115606976 6.333263082873936E-51 forebrain_development GO:0030900 12133 242 66 2 3152 19 3 false 0.43487442835557083 0.43487442835557083 0.0 viral_protein_processing GO:0019082 12133 10 66 1 256 14 2 false 0.43607433246832206 0.43607433246832206 3.5864633505920636E-18 interleukin-2_production GO:0032623 12133 39 66 1 362 5 1 false 0.43635152102464103 0.43635152102464103 2.768478137430898E-53 cAMP_biosynthetic_process GO:0006171 12133 124 66 1 284 1 3 false 0.4366197183098948 0.4366197183098948 6.647675853046176E-84 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 66 5 4239 40 3 false 0.43742868158210885 0.43742868158210885 0.0 hemostasis GO:0007599 12133 447 66 5 527 5 1 false 0.4375225590465359 0.4375225590465359 7.174896528140087E-97 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 66 1 415 5 1 false 0.4383244346067863 0.4383244346067863 2.1919403735850567E-61 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 66 2 1813 21 1 false 0.439017077638707 0.439017077638707 4.219154160176784E-199 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 66 3 660 3 2 false 0.43939610578296984 0.43939610578296984 4.8010140095396714E-157 arachidonic_acid_metabolic_process GO:0019369 12133 33 66 1 75 1 3 false 0.4400000000000015 0.4400000000000015 4.917588428220888E-22 double-strand_break_repair_via_homologous_recombination GO:0000724 12133 48 66 1 109 1 2 false 0.4403669724770689 0.4403669724770689 4.364037891784993E-32 glycosyl_compound_metabolic_process GO:1901657 12133 1093 66 10 7599 64 2 false 0.4415941432003654 0.4415941432003654 0.0 ephrin_receptor_signaling_pathway GO:0048013 12133 30 66 1 586 11 1 false 0.4418869011418806 0.4418869011418806 5.184030943639595E-51 negative_regulation_of_proteolysis GO:0045861 12133 36 66 1 1010 16 3 false 0.4429758066352495 0.4429758066352495 4.887571153196073E-67 female_sex_differentiation GO:0046660 12133 93 66 1 3074 19 2 false 0.4431382845096644 0.4431382845096644 2.0765356282751238E-180 small_GTPase_regulator_activity GO:0005083 12133 234 66 2 351 2 1 false 0.44380952380958166 0.44380952380958166 2.0747066283815493E-96 tissue_homeostasis GO:0001894 12133 93 66 2 201 3 2 false 0.44385359633989896 0.44385359633989896 9.66633233825566E-60 protein_deacetylase_activity GO:0033558 12133 28 66 1 63 1 2 false 0.44444444444444187 0.44444444444444187 1.5890462849475085E-18 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 66 10 1007 10 2 false 0.44485882174180064 0.44485882174180064 1.4040993054667365E-118 cellular_response_to_peptide GO:1901653 12133 247 66 3 625 6 3 false 0.44568697227027837 0.44568697227027837 2.2359681686760748E-181 Ras_GTPase_activator_activity GO:0005099 12133 87 66 1 339 2 3 false 0.44797612190389635 0.44797612190389635 2.872872762914377E-83 regulation_of_multicellular_organismal_development GO:2000026 12133 953 66 7 3481 23 3 false 0.4481645457566122 0.4481645457566122 0.0 histone_deacetylase_activity_(H3-K9_specific) GO:0032129 12133 13 66 1 29 1 2 false 0.4482758620689651 0.4482758620689651 1.4735371515185923E-8 purine_nucleoside_metabolic_process GO:0042278 12133 1054 66 10 1257 11 2 false 0.4483861884997328 0.4483861884997328 1.399683863089717E-240 nuclear_localization_sequence_binding GO:0008139 12133 9 66 1 20 1 1 false 0.45000000000000057 0.45000000000000057 5.9537985234579775E-6 mitochondrial_outer_membrane GO:0005741 12133 96 66 1 372 2 2 false 0.4500478219285001 0.4500478219285001 1.1824719222700171E-91 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 66 10 1319 12 1 false 0.4501669513268233 0.4501669513268233 6.536050345296563E-309 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 66 11 803 14 1 false 0.45020976036655935 0.45020976036655935 1.0286714317927864E-202 proteolysis GO:0006508 12133 732 66 11 3431 48 1 false 0.45031938256776927 0.45031938256776927 0.0 protein_dimerization_activity GO:0046983 12133 779 66 7 6397 52 1 false 0.45040009322057073 0.45040009322057073 0.0 midbody GO:0030496 12133 90 66 1 9983 66 1 false 0.4510089803512404 0.4510089803512404 2.5893666131724343E-222 glomerular_epithelial_cell_differentiation GO:0072311 12133 14 66 1 31 1 2 false 0.45161290322580533 0.45161290322580533 3.770987549047572E-9 digestive_system_development GO:0055123 12133 93 66 1 2686 17 1 false 0.4516615931117399 0.4516615931117399 7.18077161222144E-175 response_to_retinoic_acid GO:0032526 12133 79 66 1 963 7 2 false 0.45180951727938073 0.45180951727938073 4.720694804744668E-118 endothelial_cell_migration GO:0043542 12133 100 66 3 130 3 1 false 0.4519789803220058 0.4519789803220058 3.8279880512589226E-30 phosphoprotein_phosphatase_activity GO:0004721 12133 206 66 2 306 2 1 false 0.4524804457301775 0.4524804457301775 2.1851087098036358E-83 nitric_oxide_metabolic_process GO:0046209 12133 58 66 1 5244 54 1 false 0.4531902836033676 0.4531902836033676 5.86322097413057E-138 cardiac_muscle_contraction GO:0060048 12133 68 66 1 150 1 2 false 0.45333333333334686 0.45333333333334686 2.0634364015669812E-44 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 66 10 1006 10 2 false 0.4542047175759436 0.4542047175759436 2.1893990019353197E-116 nucleotide-binding_oligomerization_domain_containing_1_signaling_pathway GO:0070427 12133 4 66 1 30 4 1 false 0.4544791096515244 0.4544791096515244 3.648969166210552E-5 regulation_of_multi-organism_process GO:0043900 12133 193 66 2 6817 54 2 false 0.4549607584744991 0.4549607584744991 0.0 mitochondrial_envelope GO:0005740 12133 378 66 2 803 3 2 false 0.4560976070186449 0.4560976070186449 2.632819629334664E-240 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 66 32 6094 59 2 false 0.4569547194716426 0.4569547194716426 0.0 localization_within_membrane GO:0051668 12133 37 66 1 1845 30 1 false 0.4580697893880472 0.4580697893880472 2.8489513256034824E-78 phosphorus_metabolic_process GO:0006793 12133 2805 66 26 7256 65 1 false 0.458320943557346 0.458320943557346 0.0 regulation_of_mitochondrion_organization GO:0010821 12133 64 66 1 661 6 2 false 0.45852988799288413 0.45852988799288413 9.542606350434685E-91 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 66 4 2935 29 1 false 0.4586646128087538 0.4586646128087538 0.0 recombinational_repair GO:0000725 12133 48 66 1 416 5 2 false 0.4599920167755236 0.4599920167755236 4.005015877906007E-64 spindle GO:0005819 12133 221 66 3 4762 54 4 false 0.4615100296159941 0.4615100296159941 0.0 blood_vessel_morphogenesis GO:0048514 12133 368 66 3 2812 19 3 false 0.4617540164071089 0.4617540164071089 0.0 ossification GO:0001503 12133 234 66 2 4095 27 1 false 0.4622232237609135 0.4622232237609135 0.0 response_to_extracellular_stimulus GO:0009991 12133 260 66 2 1046 6 1 false 0.4629348602763628 0.4629348602763628 6.4524154237794786E-254 membrane_protein_proteolysis GO:0033619 12133 40 66 1 732 11 1 false 0.4634129686859534 0.4634129686859534 6.346448178672535E-67 cytoplasmic_sequestering_of_NF-kappaB GO:0007253 12133 9 66 1 49 3 3 false 0.4637429439861065 0.4637429439861065 4.867469433024523E-10 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 66 1 1402 11 4 false 0.4640166405827142 0.4640166405827142 6.104501177954134E-129 ovarian_follicle_development GO:0001541 12133 39 66 1 84 1 2 false 0.4642857142857246 0.4642857142857246 7.362290770837602E-25 synapse_part GO:0044456 12133 253 66 2 10701 66 2 false 0.4649358315995035 0.4649358315995035 0.0 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 66 12 5558 56 3 false 0.46636673691684805 0.46636673691684805 0.0 spindle_microtubule GO:0005876 12133 41 66 1 415 6 2 false 0.46641453643358594 0.46641453643358594 1.180165958259782E-57 monocarboxylic_acid_metabolic_process GO:0032787 12133 287 66 1 614 1 1 false 0.4674267100978451 0.4674267100978451 1.6797243192352778E-183 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 66 10 1002 10 3 false 0.46766746289878697 0.46766746289878697 5.68242981185093E-113 response_to_pain GO:0048265 12133 22 66 1 47 1 1 false 0.4680851063829785 0.4680851063829785 6.741316548173564E-14 neural_crest_cell_migration GO:0001755 12133 28 66 1 193 4 2 false 0.4686448364285303 0.4686448364285303 2.4136350913712057E-34 ruffle_membrane GO:0032587 12133 56 66 1 207 2 3 false 0.46883354439284075 0.46883354439284075 5.291580376353652E-52 system_development GO:0048731 12133 2686 66 17 3304 20 2 false 0.4692932730285022 0.4692932730285022 0.0 mitotic_spindle_checkpoint GO:0071174 12133 38 66 1 140 2 2 false 0.4706063720451865 0.4706063720451865 3.73538767395573E-35 establishment_of_RNA_localization GO:0051236 12133 124 66 2 2839 36 2 false 0.4714001445678199 0.4714001445678199 1.4765023034812589E-220 cell_body GO:0044297 12133 239 66 2 9983 66 1 false 0.471507339089778 0.471507339089778 0.0 positive_regulation_of_histone_modification GO:0031058 12133 40 66 1 963 15 4 false 0.4733067123662394 0.4733067123662394 8.380486405163906E-72 blood_vessel_development GO:0001568 12133 420 66 3 3152 19 3 false 0.4742704270640562 0.4742704270640562 0.0 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 66 5 5027 48 3 false 0.4743050006132523 0.4743050006132523 0.0 sodium_ion_transmembrane_transport GO:0035725 12133 68 66 1 565 5 2 false 0.47460975020340074 0.47460975020340074 1.2033655972436562E-89 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 66 9 2877 26 6 false 0.4756882719257568 0.4756882719257568 0.0 negative_regulation_of_multi-organism_process GO:0043901 12133 51 66 1 3360 42 3 false 0.4760558725780274 0.4760558725780274 3.258164733926273E-114 cytoskeletal_protein_binding GO:0008092 12133 556 66 5 6397 52 1 false 0.4764188276621786 0.4764188276621786 0.0 actin_cytoskeleton GO:0015629 12133 327 66 3 1430 11 1 false 0.47739778356349627 0.47739778356349627 0.0 regulation_of_stem_cell_differentiation GO:2000736 12133 64 66 1 922 9 2 false 0.47816368191520164 0.47816368191520164 2.1519323444963246E-100 regulation_of_systemic_arterial_blood_pressure GO:0003073 12133 56 66 1 117 1 1 false 0.4786324786324643 0.4786324786324643 9.090542259133476E-35 lamellipodium GO:0030027 12133 121 66 1 990 5 2 false 0.47963257705571705 0.47963257705571705 5.739208350847419E-159 synaptic_vesicle_localization GO:0097479 12133 60 66 1 125 1 1 false 0.47999999999998433 0.47999999999998433 3.645266173593748E-37 sequestering_of_calcium_ion GO:0051208 12133 59 66 1 212 2 2 false 0.48010372887413166 0.48010372887413166 5.87797919857101E-54 regulatory_region_DNA_binding GO:0000975 12133 1169 66 9 2091 15 2 false 0.480547824609994 0.480547824609994 0.0 negative_regulation_of_developmental_process GO:0051093 12133 463 66 4 4566 35 3 false 0.4805697124041484 0.4805697124041484 0.0 mitochondrion_organization GO:0007005 12133 215 66 2 2031 15 1 false 0.48242744245428143 0.48242744245428143 4.082912305313268E-297 cellular_component_movement GO:0006928 12133 1012 66 8 7541 56 1 false 0.4831936577458794 0.4831936577458794 0.0 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 66 5 178 7 1 false 0.4834009864771272 0.4834009864771272 1.7238002808689451E-50 synaptic_membrane GO:0097060 12133 151 66 1 4420 19 2 false 0.4840853905745679 0.4840853905745679 4.006025348631899E-285 response_to_inorganic_substance GO:0010035 12133 277 66 3 2369 22 1 false 0.48415926228208284 0.48415926228208284 0.0 positive_regulation_of_ion_transport GO:0043270 12133 86 66 1 1086 8 3 false 0.48430397634937694 0.48430397634937694 6.3756507891276546E-130 male_sex_differentiation GO:0046661 12133 105 66 1 3074 19 2 false 0.48434116802744187 0.48434116802744187 4.0305150218166505E-198 DNA_modification GO:0006304 12133 62 66 1 2948 31 2 false 0.484353253391696 0.484353253391696 4.6529599905384535E-130 ribose_phosphate_metabolic_process GO:0019693 12133 1207 66 11 3007 26 3 false 0.48456480539119257 0.48456480539119257 0.0 ion_homeostasis GO:0050801 12133 532 66 3 677 3 1 false 0.48466636949761177 0.48466636949761177 5.041033537922393E-152 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 66 14 106 14 2 false 0.48526448498431307 0.48526448498431307 9.867686559172291E-9 chemotaxis GO:0006935 12133 488 66 5 2369 22 2 false 0.48575057533534494 0.48575057533534494 0.0 cell_projection_morphogenesis GO:0048858 12133 541 66 4 946 6 3 false 0.48601829675352837 0.48601829675352837 1.1683643564827775E-279 positive_regulation_of_T_cell_proliferation GO:0042102 12133 60 66 1 212 2 4 false 0.4868997585620508 0.4868997585620508 2.305089881792403E-54 regulation_of_exocytosis GO:0017157 12133 69 66 1 865 8 4 false 0.48719803596535494 0.48719803596535494 6.158108210056647E-104 regulation_of_DNA_repair GO:0006282 12133 46 66 1 508 7 3 false 0.48755868889829823 0.48755868889829823 1.525242689490639E-66 cell_part_morphogenesis GO:0032990 12133 551 66 4 810 5 1 false 0.4876445101616013 0.4876445101616013 1.1709501739830369E-219 regulation_of_homeostatic_process GO:0032844 12133 239 66 2 6742 46 2 false 0.48921769702518036 0.48921769702518036 0.0 regulation_of_protein_complex_assembly GO:0043254 12133 185 66 2 1610 14 3 false 0.4905725869046313 0.4905725869046313 1.34790682725651E-248 protein_insertion_into_membrane GO:0051205 12133 32 66 1 1452 30 3 false 0.49104542819411434 0.49104542819411434 2.4360077014496946E-66 regulation_of_catabolic_process GO:0009894 12133 554 66 6 5455 55 2 false 0.4914682592869559 0.4914682592869559 0.0 vesicle GO:0031982 12133 834 66 7 7980 63 1 false 0.4920362685024744 0.4920362685024744 0.0 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 66 1 130 1 2 false 0.4923076923076922 0.4923076923076922 1.0680656075518395E-38 cell_communication GO:0007154 12133 3962 66 30 7541 56 1 false 0.49256496622498425 0.49256496622498425 0.0 cellular_response_to_molecule_of_bacterial_origin GO:0071219 12133 101 66 1 205 1 2 false 0.49268292682926956 0.49268292682926956 3.5711217717453676E-61 mesoderm_development GO:0007498 12133 92 66 1 1132 8 1 false 0.49354528767679406 0.49354528767679406 6.19400145712131E-138 response_to_biotic_stimulus GO:0009607 12133 494 66 4 5200 38 1 false 0.493779028859909 0.493779028859909 0.0 positive_regulation_of_inflammatory_response GO:0050729 12133 58 66 1 543 6 4 false 0.49393488463619295 0.49393488463619295 1.3309637222630526E-79 cyclic_nucleotide_metabolic_process GO:0009187 12133 177 66 2 1317 12 1 false 0.4941537762898841 0.4941537762898841 5.758082552903037E-225 cellular_component_biogenesis GO:0044085 12133 1525 66 16 3839 39 1 false 0.49453821541830223 0.49453821541830223 0.0 bone_remodeling GO:0046849 12133 51 66 1 103 1 1 false 0.4951456310679525 0.4951456310679525 1.2633713261943138E-30 neuron_development GO:0048666 12133 654 66 5 1313 9 2 false 0.495300026923176 0.495300026923176 0.0 lymphocyte_costimulation GO:0031294 12133 60 66 1 1618 18 2 false 0.4953298875215876 0.4953298875215876 7.286021331162317E-111 cellular_developmental_process GO:0048869 12133 2267 66 17 7817 57 2 false 0.4954207736615025 0.4954207736615025 0.0 ATP-dependent_RNA_helicase_activity GO:0004004 12133 20 66 1 99 3 3 false 0.4958271968581023 0.4958271968581023 2.332161908415525E-21 peptidyl-serine_modification GO:0018209 12133 127 66 1 623 3 1 false 0.4959846157034221 0.4959846157034221 3.781982241942545E-136 regulation_of_lipid_biosynthetic_process GO:0046890 12133 85 66 1 3279 26 3 false 0.4961755034854748 0.4961755034854748 1.2266874982723732E-170 cell_projection_membrane GO:0031253 12133 147 66 1 1575 7 2 false 0.49703736258584574 0.49703736258584574 1.960515926193566E-211 regulation_of_phosphatase_activity GO:0010921 12133 70 66 1 1058 10 3 false 0.4971993116094746 0.4971993116094746 2.3888102715795706E-111 acid-amino_acid_ligase_activity GO:0016881 12133 351 66 9 379 9 1 false 0.49735708253112976 0.49735708253112976 5.324332733169013E-43 microtubule_binding GO:0008017 12133 106 66 2 150 2 1 false 0.49798657718121453 0.49798657718121453 5.3333104558304893E-39 cellular_potassium_ion_transport GO:0071804 12133 92 66 1 7541 56 2 false 0.49839130686163763 0.49839130686163763 4.105440908779901E-215 tissue_remodeling GO:0048771 12133 103 66 1 4095 27 1 false 0.4984384599153408 0.4984384599153408 3.129128065207337E-208 negative_regulation_of_viral_genome_replication GO:0045071 12133 27 66 1 93 2 4 false 0.49859747545580857 0.49859747545580857 5.123998834104114E-24 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 66 2 759 13 3 false 0.49869198234609224 0.49869198234609224 1.1458874617943115E-123 embryo_development GO:0009790 12133 768 66 5 3347 20 3 false 0.49933493245241367 0.49933493245241367 0.0 regulation_of_cholesterol_transport GO:0032374 12133 25 66 1 50 1 2 false 0.4999999999999955 0.4999999999999955 7.910728602448565E-15 DNA_topoisomerase_type_I_activity GO:0003917 12133 4 66 1 8 1 1 false 0.4999999999999997 0.4999999999999997 0.014285714285714268 protein_export_from_nucleus GO:0006611 12133 46 66 1 2428 36 3 false 0.5002499262069217 0.5002499262069217 1.6048237175829586E-98 endosome GO:0005768 12133 455 66 4 8213 66 2 false 0.5011706347031338 0.5011706347031338 0.0 protein_deacylation GO:0035601 12133 58 66 1 2370 28 1 false 0.5023154708580441 0.5023154708580441 8.732809717864973E-118 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 66 10 3453 40 4 false 0.5025389275319895 0.5025389275319895 0.0 protein_N-terminus_binding GO:0047485 12133 85 66 1 6397 52 1 false 0.5026130556714707 0.5026130556714707 1.5319897739448716E-195 chromatin_remodeling GO:0006338 12133 95 66 1 458 3 1 false 0.5029776977249808 0.5029776977249808 6.184896180355641E-101 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 66 12 2595 25 2 false 0.5030233289637742 0.5030233289637742 0.0 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 66 12 307 17 1 false 0.5033878475136427 0.5033878475136427 1.4733469150792184E-83 gland_development GO:0048732 12133 251 66 2 2873 19 2 false 0.5043652575146939 0.5043652575146939 0.0 negative_regulation_of_cell_adhesion GO:0007162 12133 78 66 1 2936 26 3 false 0.5049595110006186 0.5049595110006186 1.0404104256027157E-155 vacuolar_part GO:0044437 12133 186 66 2 7185 65 3 false 0.5051016534599561 0.5051016534599561 0.0 polysaccharide_catabolic_process GO:0000272 12133 24 66 1 942 27 3 false 0.5067521407530786 0.5067521407530786 3.497848871187908E-48 synaptic_vesicle GO:0008021 12133 71 66 1 339 3 2 false 0.5070743785164036 0.5070743785164036 5.19989458377584E-75 regulation_of_release_of_sequestered_calcium_ion_into_cytosol GO:0051279 12133 34 66 1 67 1 2 false 0.5074626865671725 0.5074626865671725 7.029125521573557E-20 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 66 1 2474 27 3 false 0.5090693229629182 0.5090693229629182 1.917782059478808E-128 morphogenesis_of_embryonic_epithelium GO:0016331 12133 113 66 1 536 3 2 false 0.5092333016219698 0.5092333016219698 3.034362730602184E-119 regulation_of_mRNA_3'-end_processing GO:0031440 12133 15 66 1 115 5 2 false 0.509451331812173 0.509451331812173 4.172184298573769E-19 tube_formation GO:0035148 12133 102 66 1 2776 19 3 false 0.5101402358956011 0.5101402358956011 3.715346620703698E-189 T_cell_activation GO:0042110 12133 288 66 2 403 2 1 false 0.5102033258028115 0.5102033258028115 5.060432780788644E-104 telomere_maintenance GO:0000723 12133 61 66 1 888 10 3 false 0.5110212373281687 0.5110212373281687 5.866244325488287E-96 positive_regulation_of_cell_death GO:0010942 12133 383 66 4 3330 32 3 false 0.5110929638919849 0.5110929638919849 0.0 regulation_of_mitosis GO:0007088 12133 100 66 1 611 4 4 false 0.5117068254339328 0.5117068254339328 1.2375244614825155E-117 sodium_ion_transmembrane_transporter_activity GO:0015081 12133 67 66 1 316 3 3 false 0.5119990171348612 0.5119990171348612 2.2934303131006308E-70 regulation_of_DNA_metabolic_process GO:0051052 12133 188 66 2 4316 39 3 false 0.5121636861362289 0.5121636861362289 0.0 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_linear_amides GO:0016811 12133 42 66 1 82 1 1 false 0.5121951219512042 0.5121951219512042 2.4115523257823617E-24 T_cell_apoptotic_process GO:0070231 12133 20 66 1 39 1 1 false 0.5128205128205103 0.5128205128205103 1.4508889103849471E-11 amino_acid_transport GO:0006865 12133 78 66 1 475 4 2 false 0.5132522872018294 0.5132522872018294 1.5149917368485561E-91 positive_regulation_of_organelle_organization GO:0010638 12133 217 66 2 2191 17 3 false 0.5135849631868596 0.5135849631868596 1.6765812392172608E-306 regulation_of_calcium_ion_transport_into_cytosol GO:0010522 12133 45 66 1 400 6 4 false 0.5136763416407288 0.5136763416407288 1.265400495068792E-60 regulation_of_type_I_interferon-mediated_signaling_pathway GO:0060338 12133 24 66 1 282 8 3 false 0.5137300062682215 0.5137300062682215 2.655253961660049E-35 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 66 3 252 4 2 false 0.5148534033687004 0.5148534033687004 5.925442745937436E-72 positive_regulation_of_cAMP_biosynthetic_process GO:0030819 12133 69 66 1 134 1 5 false 0.5149253731343213 0.5149253731343213 7.0817799397690005E-40 positive_regulation_of_extrinsic_apoptotic_signaling_pathway GO:2001238 12133 21 66 1 99 3 3 false 0.5149729995090585 0.5149729995090585 6.199417731230936E-22 multicellular_organismal_process GO:0032501 12133 4223 66 27 10446 66 1 false 0.5150421504625786 0.5150421504625786 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 66 5 147 5 1 false 0.5154033496026863 0.5154033496026863 1.843896992838607E-23 gland_morphogenesis GO:0022612 12133 105 66 1 2812 19 3 false 0.5158757314081217 0.5158757314081217 5.511647482343512E-194 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 66 3 450 8 2 false 0.516110303992779 0.516110303992779 8.40005869125793E-123 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 66 16 181 16 1 false 0.5171604421585043 0.5171604421585043 8.905994863592909E-13 tissue_morphogenesis GO:0048729 12133 415 66 3 2931 19 3 false 0.5174096514484656 0.5174096514484656 0.0 positive_regulation_of_lyase_activity GO:0051349 12133 64 66 1 1165 13 3 false 0.5221458720625066 0.5221458720625066 4.208539259642897E-107 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 66 2 341 8 4 false 0.5224878634823772 0.5224878634823772 3.257446469032824E-75 transport GO:0006810 12133 2783 66 36 2833 36 1 false 0.5246248251813342 0.5246248251813342 1.147202604491021E-108 regulation_of_cyclic_nucleotide_metabolic_process GO:0030799 12133 156 66 2 478 5 2 false 0.525890425427524 0.525890425427524 1.998151187516486E-130 prostanoid_biosynthetic_process GO:0046457 12133 20 66 1 38 1 3 false 0.5263157894736858 0.5263157894736858 2.978140395000689E-11 divalent_inorganic_cation_transport GO:0072511 12133 243 66 2 606 4 1 false 0.5268003957658728 0.5268003957658728 1.781632444658852E-176 cytosolic_calcium_ion_homeostasis GO:0051480 12133 149 66 2 205 2 1 false 0.5273075083691899 0.5273075083691899 9.962188539004893E-52 epithelial_to_mesenchymal_transition GO:0001837 12133 71 66 1 607 6 2 false 0.5274739462962907 0.5274739462962907 1.494030072752519E-94 maintenance_of_location_in_cell GO:0051651 12133 100 66 1 7542 56 3 false 0.5277432293154917 0.5277432293154917 3.2184799576057033E-230 response_to_exogenous_dsRNA GO:0043330 12133 19 66 1 36 1 1 false 0.5277777777777791 0.5277777777777791 1.163129276491937E-10 negative_regulation_of_extrinsic_apoptotic_signaling_pathway GO:2001237 12133 18 66 1 82 3 3 false 0.5295392953929461 0.5295392953929461 1.7089577417430564E-18 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 66 3 859 13 3 false 0.5299489288909194 0.5299489288909194 3.480270935062193E-190 regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014066 12133 54 66 1 1607 22 2 false 0.530935979654305 0.530935979654305 4.2614304493416375E-102 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 66 8 1079 18 3 false 0.5317257819356804 0.5317257819356804 5.98264E-319 synaptic_vesicle_transport GO:0048489 12133 58 66 1 2643 34 4 false 0.5319751610668031 0.5319751610668031 1.4559500862044685E-120 positive_regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014068 12133 45 66 1 798 13 3 false 0.532552713586921 0.532552713586921 1.088358768929943E-74 brain_development GO:0007420 12133 420 66 3 2904 19 3 false 0.5327367863849893 0.5327367863849893 0.0 cytosolic_calcium_ion_transport GO:0060401 12133 72 66 1 228 2 1 false 0.5328077904010786 0.5328077904010786 3.105695995462917E-61 small_conjugating_protein-specific_protease_activity GO:0019783 12133 51 66 1 295 4 1 false 0.5339755631703187 0.5339755631703187 1.675313493425089E-58 cellular_polysaccharide_metabolic_process GO:0044264 12133 67 66 1 5670 64 3 false 0.5346887035274314 0.5346887035274314 1.7454278483133037E-157 phosphorus-oxygen_lyase_activity GO:0016849 12133 123 66 1 230 1 1 false 0.5347826086956033 0.5347826086956033 1.920154677041111E-68 negative_regulation_of_endothelial_cell_migration GO:0010596 12133 23 66 1 103 3 3 false 0.5354281287637446 0.5354281287637446 1.8683564084133473E-23 positive_regulation_of_endocytosis GO:0045807 12133 63 66 1 1023 12 4 false 0.5355979929969085 0.5355979929969085 3.3235317732048763E-102 sodium_ion_transport GO:0006814 12133 95 66 1 545 4 2 false 0.5362863567124639 0.5362863567124639 6.918862196703055E-109 polysaccharide_metabolic_process GO:0005976 12133 74 66 1 6221 64 2 false 0.5368871911637341 0.5368871911637341 9.187602528598046E-174 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 66 2 361 5 1 false 0.5381795009194307 0.5381795009194307 4.560830022372086E-99 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 66 10 4429 47 3 false 0.5392323347739665 0.5392323347739665 0.0 cholesterol_efflux GO:0033344 12133 27 66 1 50 1 1 false 0.539999999999996 0.539999999999996 9.255552464864819E-15 protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:0001844 12133 25 66 1 305 9 3 false 0.5417989891719257 0.5417989891719257 3.3284741778861134E-37 ceramide_metabolic_process GO:0006672 12133 37 66 1 68 1 1 false 0.5441176470588207 0.5441176470588207 4.563528183708786E-20 cellular_response_to_starvation GO:0009267 12133 87 66 1 1156 10 3 false 0.5441573716211284 0.5441573716211284 1.942511852273073E-133 cell_activation GO:0001775 12133 656 66 5 7541 56 1 false 0.5443858978999976 0.5443858978999976 0.0 poly-pyrimidine_tract_binding GO:0008187 12133 9 66 1 40 3 1 false 0.5450404858299631 0.5450404858299631 3.657124400158464E-9 receptor_internalization GO:0031623 12133 54 66 1 2372 34 3 false 0.5454920108105731 0.5454920108105731 2.350294022700988E-111 activating_transcription_factor_binding GO:0033613 12133 294 66 4 715 9 1 false 0.5458111265372196 0.5458111265372196 1.6086726333731214E-209 vasculature_development GO:0001944 12133 441 66 3 2686 17 2 false 0.54598322574176 0.54598322574176 0.0 cell_maturation GO:0048469 12133 103 66 1 2274 17 3 false 0.5465381514503969 0.5465381514503969 1.840769362414338E-181 regulation_of_mitochondrial_outer_membrane_permeabilization GO:1901028 12133 33 66 1 354 8 4 false 0.5466543811359023 0.5466543811359023 3.0911895026883726E-47 ion_channel_complex GO:0034702 12133 123 66 1 5051 32 3 false 0.5467710590076192 0.5467710590076192 1.657407747533362E-250 negative_regulation_of_response_to_external_stimulus GO:0032102 12133 105 66 1 1508 11 3 false 0.5491537610474966 0.5491537610474966 8.164414473234676E-165 organelle_assembly GO:0070925 12133 210 66 2 2677 23 2 false 0.5491650039569712 0.5491650039569712 7.5039E-319 positive_regulation_of_cyclase_activity GO:0031281 12133 63 66 1 1064 13 3 false 0.5498246022292059 0.5498246022292059 2.5891490792503797E-103 tetrapyrrole_binding GO:0046906 12133 79 66 1 4407 44 2 false 0.5506012841120624 0.5506012841120624 2.34302834047957E-171 platelet_degranulation GO:0002576 12133 81 66 1 246 2 1 false 0.5510204081633053 0.5510204081633053 3.708744059509268E-67 regulation_of_receptor_activity GO:0010469 12133 89 66 1 3057 27 3 false 0.5512088800967551 0.5512088800967551 3.874143452259453E-174 regulation_of_DNA_replication GO:0006275 12133 92 66 1 2913 25 3 false 0.553215573288887 0.553215573288887 1.0142928746758388E-176 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 66 1 557 27 2 false 0.5534484079824462 0.5534484079824462 3.0295698614548545E-31 protein_ubiquitination GO:0016567 12133 548 66 11 578 11 1 false 0.5534635476337151 0.5534635476337151 7.913703273197485E-51 organelle_outer_membrane GO:0031968 12133 110 66 1 9084 66 4 false 0.5538027521290805 0.5538027521290805 1.1973077012984011E-257 oogenesis GO:0048477 12133 36 66 1 65 1 1 false 0.5538461538461481 0.5538461538461481 3.9878950035701057E-19 DNA_metabolic_process GO:0006259 12133 791 66 9 5627 64 2 false 0.5546534093489837 0.5546534093489837 0.0 multicellular_organismal_signaling GO:0035637 12133 604 66 4 5594 36 2 false 0.55490360541056 0.55490360541056 0.0 positive_regulation_of_mononuclear_cell_proliferation GO:0032946 12133 90 66 1 162 1 3 false 0.5555555555555203 0.5555555555555203 7.398344320116603E-48 NAD-dependent_histone_deacetylase_activity GO:0017136 12133 15 66 1 27 1 2 false 0.5555555555555558 0.5555555555555558 5.75246234150529E-8 G1_DNA_damage_checkpoint GO:0044783 12133 70 66 1 126 1 1 false 0.5555555555555676 0.5555555555555676 3.590272155218709E-37 kinase_activity GO:0016301 12133 1174 66 14 1546 18 2 false 0.5560252126747233 0.5560252126747233 0.0 MAPK_cascade GO:0000165 12133 502 66 9 806 14 1 false 0.5571330025560586 0.5571330025560586 3.7900857366173457E-231 leukocyte_proliferation GO:0070661 12133 167 66 1 1316 6 1 false 0.5577547232531918 0.5577547232531918 1.1010684152010674E-216 positive_regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900740 12133 24 66 1 43 1 3 false 0.558139534883719 0.558139534883719 1.2492622608986976E-12 calcium-mediated_signaling GO:0019722 12133 86 66 1 257 2 1 false 0.5581529669260303 0.5581529669260303 1.363801895693069E-70 intracellular_transport_of_viral_material GO:0075733 12133 23 66 1 355 12 2 false 0.5582312590246705 0.5582312590246705 1.1844258992565298E-36 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 66 12 5151 56 4 false 0.5589334328799813 0.5589334328799813 0.0 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 66 4 766 6 2 false 0.5589838079994429 0.5589838079994429 4.217322594612318E-222 regulation_of_leukocyte_proliferation GO:0070663 12133 131 66 1 1029 6 2 false 0.5592029427160484 0.5592029427160484 1.1421072529969205E-169 regulation_of_peptide_hormone_secretion GO:0090276 12133 131 66 2 175 2 3 false 0.5592775041051111 0.5592775041051111 2.0027366567035167E-42 protein_folding GO:0006457 12133 183 66 3 3038 48 1 false 0.5600597053678793 0.5600597053678793 1.582632936584301E-299 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 66 10 4298 47 4 false 0.5602835830853437 0.5602835830853437 0.0 cyclic_purine_nucleotide_metabolic_process GO:0052652 12133 151 66 1 269 1 2 false 0.5613382899628113 0.5613382899628113 1.6379011785432358E-79 DNA_biosynthetic_process GO:0071897 12133 268 66 3 3979 43 3 false 0.5614918847437363 0.5614918847437363 0.0 regulation_of_programmed_cell_death GO:0043067 12133 1031 66 12 1410 16 2 false 0.5619002755023413 0.5619002755023413 0.0 Golgi_to_plasma_membrane_protein_transport GO:0043001 12133 24 66 1 662 22 2 false 0.5621256553771252 0.5621256553771252 1.885213981643603E-44 establishment_of_synaptic_vesicle_localization GO:0097480 12133 58 66 1 103 1 2 false 0.5631067961164882 0.5631067961164882 2.8393636852325753E-30 regulation_of_cellular_response_to_stress GO:0080135 12133 270 66 2 6503 45 3 false 0.5633539529971687 0.5633539529971687 0.0 monosaccharide_metabolic_process GO:0005996 12133 217 66 1 385 1 1 false 0.5636363636363345 0.5636363636363345 7.061110236111427E-114 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 66 10 3780 44 4 false 0.5639894027459667 0.5639894027459667 0.0 negative_regulation_of_reproductive_process GO:2000242 12133 65 66 1 3420 43 3 false 0.5640711331793303 0.5640711331793303 2.9542142879788904E-139 protein_complex_biogenesis GO:0070271 12133 746 66 8 1525 16 1 false 0.5642207663668589 0.5642207663668589 0.0 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 66 1 594 10 3 false 0.564337668707684 0.564337668707684 7.186758669481106E-71 cell_cycle_phase_transition GO:0044770 12133 415 66 5 953 11 1 false 0.5647478473835816 0.5647478473835816 1.4433288987581492E-282 synapse_organization GO:0050808 12133 109 66 1 7663 58 2 false 0.5657154785876031 0.5657154785876031 1.245153875786693E-247 DNA_replication GO:0006260 12133 257 66 3 3702 42 3 false 0.5664194503088387 0.5664194503088387 0.0 regulation_of_cell_migration GO:0030334 12133 351 66 4 749 8 2 false 0.5666476194232579 0.5666476194232579 5.057884988188172E-224 negative_regulation_of_protein_catabolic_process GO:0042177 12133 43 66 1 851 16 4 false 0.5670791114583623 0.5670791114583623 1.831793147974944E-73 myeloid_cell_differentiation GO:0030099 12133 237 66 2 2177 17 2 false 0.5672524654801314 0.5672524654801314 0.0 negative_regulation_of_defense_response GO:0031348 12133 72 66 1 1505 17 3 false 0.5674084897648983 0.5674084897648983 5.674310231559274E-125 mitochondrial_membrane_organization GO:0007006 12133 62 66 1 924 12 2 false 0.5677122208407863 0.5677122208407863 3.431124286579491E-98 cyclase_activity GO:0009975 12133 123 66 1 4901 33 1 false 0.5689598404436906 0.5689598404436906 7.077862449152851E-249 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 66 4 147 6 1 false 0.5701511492559113 0.5701511492559113 3.485982605742994E-42 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 66 3 3785 36 2 false 0.5708563772116841 0.5708563772116841 0.0 induction_of_programmed_cell_death GO:0012502 12133 157 66 2 368 4 1 false 0.5708921289377847 0.5708921289377847 2.1106051638808005E-108 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 66 4 217 8 1 false 0.5710508769512671 0.5710508769512671 1.2933579260360868E-64 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 66 1 1209 12 3 false 0.5712195754045664 0.5712195754045664 1.376514335843937E-129 glomerular_visceral_epithelial_cell_development GO:0072015 12133 8 66 1 14 1 2 false 0.5714285714285714 0.5714285714285714 3.330003330003327E-4 NAD-dependent_protein_deacetylase_activity GO:0034979 12133 16 66 1 28 1 1 false 0.5714285714285725 0.5714285714285725 3.287121338003005E-8 regulation_of_cellular_component_organization GO:0051128 12133 1152 66 9 7336 58 2 false 0.5714975750674847 0.5714975750674847 0.0 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 66 2 506 5 3 false 0.5719679086499312 0.5719679086499312 1.5079927652081954E-141 negative_regulation_of_mRNA_splicing,_via_spliceosome GO:0048025 12133 11 66 1 207 15 4 false 0.57214670332974 0.57214670332974 1.749347829328537E-18 organophosphate_metabolic_process GO:0019637 12133 1549 66 13 7521 64 2 false 0.572250893916913 0.572250893916913 0.0 substrate-specific_transporter_activity GO:0022892 12133 620 66 3 746 3 1 false 0.5735915936445926 0.5735915936445926 1.886990037563331E-146 ureteric_bud_development GO:0001657 12133 84 66 1 439 4 2 false 0.5737715576328308 0.5737715576328308 1.7545381819283125E-92 cellular_ion_homeostasis GO:0006873 12133 478 66 3 575 3 2 false 0.5738770660640209 0.5738770660640209 1.064446434652655E-112 maintenance_of_location GO:0051235 12133 184 66 2 4158 43 2 false 0.5741540668493061 0.5741540668493061 0.0 T_cell_proliferation GO:0042098 12133 112 66 1 322 2 2 false 0.575375863470099 0.575375863470099 9.553081503514794E-90 nuclear_speck GO:0016607 12133 147 66 3 272 5 1 false 0.576055263259039 0.576055263259039 6.6218564870724965E-81 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 66 3 1279 12 3 false 0.5761342074344041 0.5761342074344041 9.116385096369177E-305 axonogenesis GO:0007409 12133 421 66 4 483 4 2 false 0.5761574849389106 0.5761574849389106 7.423880338325494E-80 induction_of_apoptosis GO:0006917 12133 156 66 2 363 4 2 false 0.5761649533199166 0.5761649533199166 4.583372865169243E-107 stem_cell_differentiation GO:0048863 12133 239 66 2 2154 17 1 false 0.5781884525428047 0.5781884525428047 0.0 ligand-gated_channel_activity GO:0022834 12133 118 66 1 204 1 1 false 0.578431372549022 0.578431372549022 8.558639163508173E-60 vesicle_localization GO:0051648 12133 125 66 1 216 1 1 false 0.5787037037037176 0.5787037037037176 2.540191866626041E-63 intramolecular_oxidoreductase_activity GO:0016860 12133 43 66 1 123 2 1 false 0.5788351326136157 0.5788351326136157 3.559837991950172E-34 metanephric_nephron_development GO:0072210 12133 36 66 1 103 2 2 false 0.5790976584808543 0.5790976584808543 1.370003625260278E-28 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 66 1 1663 23 2 false 0.5791020115913863 0.5791020115913863 5.186655572840897E-113 immune_effector_process GO:0002252 12133 445 66 5 1618 18 1 false 0.5791396138404261 0.5791396138404261 0.0 cellular_component_assembly GO:0022607 12133 1392 66 14 3836 39 2 false 0.580571887447562 0.580571887447562 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 66 10 1014 14 1 false 0.581767061593707 0.581767061593707 1.8231541307779663E-268 BMP_signaling_pathway GO:0030509 12133 83 66 1 1276 13 2 false 0.5846564912539295 0.5846564912539295 9.874891335860256E-133 regulation_of_ion_homeostasis GO:2000021 12133 124 66 1 630 4 2 false 0.5848337541067834 0.5848337541067834 4.993626171436977E-135 positive_regulation_of_apoptotic_process GO:0043065 12133 362 66 4 1377 15 3 false 0.5851479571895013 0.5851479571895013 0.0 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 66 2 415 5 3 false 0.5852311768388281 0.5852311768388281 9.462933237946419E-117 negative_regulation_of_blood_vessel_endothelial_cell_migration GO:0043537 12133 15 66 1 60 3 3 false 0.5853302162478173 0.5853302162478173 1.8799081160635002E-14 cytokine_receptor_binding GO:0005126 12133 172 66 2 918 10 1 false 0.5860455167458296 0.5860455167458296 1.4338329427110724E-191 negative_regulation_of_cell_proliferation GO:0008285 12133 455 66 4 2949 26 3 false 0.5862184520277174 0.5862184520277174 0.0 regulation_of_hormone_secretion GO:0046883 12133 155 66 2 2003 25 5 false 0.5880953334485117 0.5880953334485117 3.773183112631131E-236 telencephalon_development GO:0021537 12133 141 66 1 3099 19 2 false 0.5882739932525127 0.5882739932525127 2.6342742970069075E-248 JNK_cascade GO:0007254 12133 159 66 2 207 2 1 false 0.5891374700998838 0.5891374700998838 3.1556682987155503E-48 neural_crest_cell_development GO:0014032 12133 39 66 1 109 2 2 false 0.5897043832823704 0.5897043832823704 1.6922524549323042E-30 transcription-coupled_nucleotide-excision_repair GO:0006283 12133 46 66 1 78 1 1 false 0.589743589743583 0.589743589743583 1.2785885050503116E-22 endosomal_transport GO:0016197 12133 133 66 2 2454 36 2 false 0.5898367208037607 0.5898367208037607 7.966947585336105E-224 sequestering_of_metal_ion GO:0051238 12133 66 66 1 184 2 1 false 0.5899857448324715 0.5899857448324715 1.1443253764330313E-51 cell-cell_junction_organization GO:0045216 12133 152 66 3 181 3 1 false 0.5903474387069662 0.5903474387069662 3.1886200066761254E-34 bone_resorption GO:0045453 12133 38 66 1 106 2 2 false 0.5906558849955024 0.5906558849955024 1.1315856884017788E-29 clathrin_coat GO:0030118 12133 39 66 1 66 1 1 false 0.5909090909090968 0.5909090909090968 4.080314872103393E-19 amino_acid_binding GO:0016597 12133 110 66 1 186 1 1 false 0.5913978494623976 0.5913978494623976 3.905422178213833E-54 Fc_receptor_signaling_pathway GO:0038093 12133 76 66 3 188 7 1 false 0.5918321343825481 0.5918321343825481 1.381050418692459E-54 regulation_of_tyrosine_phosphorylation_of_Stat3_protein GO:0042516 12133 29 66 1 49 1 2 false 0.591836734693884 0.591836734693884 3.536377094612393E-14 cell_cycle_phase GO:0022403 12133 253 66 3 953 11 1 false 0.5926988138666462 0.5926988138666462 1.0384727319913012E-238 positive_regulation_of_apoptotic_signaling_pathway GO:2001235 12133 47 66 1 973 18 3 false 0.5931285162151861 0.5931285162151861 2.8956045317480326E-81 cellular_metal_ion_homeostasis GO:0006875 12133 259 66 3 308 3 2 false 0.5935291795128598 0.5935291795128598 3.9623191237847456E-58 DNA-dependent_transcription,_initiation GO:0006352 12133 225 66 3 2751 37 2 false 0.5938759100435441 0.5938759100435441 0.0 organelle_organization GO:0006996 12133 2031 66 15 7663 58 2 false 0.5941799145499336 0.5941799145499336 0.0 RNA_stabilization GO:0043489 12133 22 66 1 37 1 1 false 0.5945945945945961 0.5945945945945961 1.0678969112465738E-10 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 66 2 136 2 2 false 0.5947712418300675 0.5947712418300675 2.4301849830786213E-31 regulation_of_chromosome_organization GO:0033044 12133 114 66 1 1070 8 2 false 0.595208893451874 0.595208893451874 5.856752364330647E-157 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 66 1 818 12 2 false 0.5953207008725336 0.5953207008725336 1.6613120232447818E-91 protein_heterodimerization_activity GO:0046982 12133 317 66 3 779 7 1 false 0.5957122808785918 0.5957122808785918 8.49214053182804E-228 zinc_ion_binding GO:0008270 12133 1314 66 5 1457 5 1 false 0.5961478373621497 0.5961478373621497 2.194714234876188E-202 regulation_of_phospholipase_C_activity GO:1900274 12133 92 66 2 119 2 2 false 0.5962113659023054 0.5962113659023054 2.4296023527654974E-27 potassium_ion_transmembrane_transport GO:0071805 12133 92 66 1 556 5 2 false 0.5966723873489893 0.5966723873489893 1.0312185181817459E-107 DNA_alkylation GO:0006305 12133 37 66 1 62 1 1 false 0.5967741935483936 0.5967741935483936 6.784005293429779E-18 metal_ion_homeostasis GO:0055065 12133 278 66 3 330 3 1 false 0.5968290661076291 0.5968290661076291 6.131976736615521E-62 positive_regulation_of_lymphocyte_proliferation GO:0050671 12133 89 66 1 244 2 4 false 0.5974161775617952 0.5974161775617952 5.620227070102447E-69 transcription_coactivator_activity GO:0003713 12133 264 66 3 478 5 2 false 0.5977564753878319 0.5977564753878319 4.798051856605128E-142 regulation_of_nuclear_division GO:0051783 12133 100 66 1 712 6 2 false 0.5980933606616345 0.5980933606616345 7.811073934054147E-125 hydrolase_activity GO:0016787 12133 2556 66 17 4901 33 1 false 0.5987575901536802 0.5987575901536802 0.0 regulation_of_neurotransmitter_levels GO:0001505 12133 101 66 1 2270 20 2 false 0.5991598324394111 0.5991598324394111 9.918769112218752E-179 Golgi_to_plasma_membrane_transport GO:0006893 12133 28 66 1 698 22 2 false 0.5994185266336094 0.5994185266336094 1.2431713448990412E-50 activation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0006919 12133 81 66 1 1375 15 3 false 0.5997028256625125 0.5997028256625125 4.023711257429167E-133 apoptotic_mitochondrial_changes GO:0008637 12133 87 66 1 1476 15 2 false 0.5997880523677992 0.5997880523677992 5.447605955370739E-143 iron_ion_transport GO:0006826 12133 36 66 1 60 1 1 false 0.6000000000000054 0.6000000000000054 2.7737414075406367E-17 mRNA_processing GO:0006397 12133 374 66 15 763 31 2 false 0.6000070866197765 0.6000070866197765 8.270510506831645E-229 cellular_response_to_lipid GO:0071396 12133 242 66 3 1527 19 2 false 0.6001686843556173 0.6001686843556173 4.5218037632292525E-289 regulation_of_protein_transport GO:0051223 12133 261 66 4 1665 26 3 false 0.6003863023627546 0.6003863023627546 3.65102727546E-313 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 66 1 953 11 3 false 0.6011727824819187 0.6011727824819187 1.5807807987211998E-114 cellular_response_to_lipopolysaccharide GO:0071222 12133 96 66 1 676 6 4 false 0.6025492560592833 0.6025492560592833 2.5099220445840513E-119 generation_of_a_signal_involved_in_cell-cell_signaling GO:0003001 12133 271 66 2 7541 56 2 false 0.6033378152091082 0.6033378152091082 0.0 signal_release GO:0023061 12133 271 66 2 7541 56 2 false 0.6033378152091082 0.6033378152091082 0.0 cytoskeletal_part GO:0044430 12133 1031 66 10 5573 56 2 false 0.6040111802421709 0.6040111802421709 0.0 cell-substrate_adhesion GO:0031589 12133 190 66 1 712 3 1 false 0.6065372465200985 0.6065372465200985 1.237947563614388E-178 cellular_response_to_inorganic_substance GO:0071241 12133 73 66 1 1690 21 2 false 0.6066012359436587 0.6066012359436587 5.009564075302306E-130 positive_regulation_of_cell_activation GO:0050867 12133 215 66 2 3002 28 3 false 0.6067436344963626 0.6067436344963626 0.0 positive_regulation_of_transport GO:0051050 12133 413 66 4 4769 48 3 false 0.6074759138359691 0.6074759138359691 0.0 intrinsic_apoptotic_signaling_pathway_by_p53_class_mediator GO:0072332 12133 32 66 1 224 6 2 false 0.6079111143918621 0.6079111143918621 1.6688930470931678E-39 lymphocyte_homeostasis GO:0002260 12133 43 66 2 55 2 1 false 0.6080808080808047 0.6080808080808047 2.27930752242823E-12 response_to_nitrogen_compound GO:1901698 12133 552 66 5 2369 22 1 false 0.6081001021121366 0.6081001021121366 0.0 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 66 12 2807 26 3 false 0.6097474121136488 0.6097474121136488 0.0 response_to_corticosteroid_stimulus GO:0031960 12133 102 66 1 272 2 1 false 0.6102398523984609 0.6102398523984609 1.4208784693795558E-77 positive_regulation_of_cell_cycle GO:0045787 12133 98 66 1 3492 33 3 false 0.6108358815203384 0.6108358815203384 2.23767062140918E-193 regulation_of_T_cell_proliferation GO:0042129 12133 89 66 1 237 2 3 false 0.6110276764642888 0.6110276764642888 1.4162064176617287E-67 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 66 4 803 14 1 false 0.6117264099401849 0.6117264099401849 7.141936114023743E-209 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 66 1 1672 23 5 false 0.6120972047873197 0.6120972047873197 1.5388096674355026E-121 peptidase_activity GO:0008233 12133 614 66 4 2556 17 1 false 0.612155597271608 0.612155597271608 0.0 nucleotide-binding_oligomerization_domain_containing_2_signaling_pathway GO:0070431 12133 6 66 1 30 4 1 false 0.6122605363984696 0.6122605363984696 1.684139615174105E-6 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 66 1 170 2 3 false 0.6126000696135618 0.6126000696135618 2.004129732487635E-48 chromatin_modification GO:0016568 12133 458 66 3 539 3 1 false 0.6129163324296396 0.6129163324296396 1.802023694196357E-98 potassium_ion_transport GO:0006813 12133 115 66 1 545 4 2 false 0.6136304663702553 0.6136304663702553 2.5935886393871475E-121 cell_periphery GO:0071944 12133 2667 66 17 9983 66 1 false 0.6164153103409411 0.6164153103409411 0.0 cellular_protein_complex_disassembly GO:0043624 12133 149 66 14 154 14 1 false 0.6168185867034919 0.6168185867034919 1.4793035521715585E-9 ATPase_activity,_coupled GO:0042623 12133 228 66 4 307 5 1 false 0.6172576158572198 0.6172576158572198 1.7947531856464704E-75 histone_deacetylase_binding GO:0042826 12133 62 66 1 1005 15 1 false 0.6179050864140622 0.6179050864140622 1.577479125629217E-100 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 66 1 278 3 3 false 0.6179292635583233 0.6179292635583233 2.8121052478162137E-70 single-organism_developmental_process GO:0044767 12133 2776 66 19 8064 57 2 false 0.618060585354924 0.618060585354924 0.0 lymphocyte_apoptotic_process GO:0070227 12133 39 66 1 63 1 1 false 0.6190476190476191 0.6190476190476191 6.383425933246293E-18 mitochondrial_membrane GO:0031966 12133 359 66 2 1810 10 3 false 0.6198265728141452 0.6198265728141452 0.0 cellular_response_to_biotic_stimulus GO:0071216 12133 112 66 1 4357 37 2 false 0.6200088319669677 0.6200088319669677 2.1448689284216048E-225 positive_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090100 12133 57 66 1 918 15 3 false 0.6206131275893044 0.6206131275893044 3.1386577853752424E-92 transcription_corepressor_activity GO:0003714 12133 180 66 2 479 5 2 false 0.6209284713153476 0.6209284713153476 5.2319775680795235E-137 cellular_response_to_steroid_hormone_stimulus GO:0071383 12133 91 66 1 706 7 4 false 0.6210614847401772 0.6210614847401772 3.3411431818141285E-117 integrin_binding GO:0005178 12133 72 66 1 1079 14 2 false 0.6220183768771228 0.6220183768771228 2.8956297077388104E-114 neuron_projection_morphogenesis GO:0048812 12133 475 66 4 637 5 2 false 0.6236787962869448 0.6236787962869448 3.7535814082411355E-156 positive_regulation_of_phospholipase_C_activity GO:0010863 12133 91 66 2 115 2 3 false 0.624713958810076 0.624713958810076 2.8677617706911523E-25 regulation_of_Wnt_receptor_signaling_pathway GO:0030111 12133 156 66 2 1668 22 2 false 0.6247536461097071 0.6247536461097071 2.89270864030114E-224 plasma_membrane GO:0005886 12133 2594 66 16 10252 66 3 false 0.6253569780275289 0.6253569780275289 0.0 regulation_of_cell-substrate_junction_assembly GO:0090109 12133 27 66 1 70 2 2 false 0.6260869565217374 0.6260869565217374 5.491922830490753E-20 developmental_process GO:0032502 12133 3447 66 21 10446 66 1 false 0.6263678195431932 0.6263678195431932 0.0 rRNA_binding GO:0019843 12133 29 66 1 763 25 1 false 0.6264140868000587 0.6264140868000587 3.8668021308986908E-53 immune_system_development GO:0002520 12133 521 66 4 3460 28 2 false 0.6268627838396174 0.6268627838396174 0.0 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 66 1 148 4 3 false 0.6268880006648783 0.6268880006648783 3.492638478654734E-33 'de_novo'_protein_folding GO:0006458 12133 51 66 1 183 3 1 false 0.6271041701709152 0.6271041701709152 1.4322240237766098E-46 tyrosine_phosphorylation_of_Stat3_protein GO:0042503 12133 32 66 1 51 1 1 false 0.6274509803921535 0.6274509803921535 2.0635800457973343E-14 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 66 4 1759 22 2 false 0.6275644150298765 0.6275644150298765 0.0 negative_regulation_of_kinase_activity GO:0033673 12133 172 66 2 1181 14 3 false 0.6276460953970918 0.6276460953970918 3.9159843646516213E-212 antigen_processing_and_presentation GO:0019882 12133 185 66 2 1618 18 1 false 0.6278313797323347 0.6278313797323347 5.091289488805967E-249 negative_regulation_of_cell_development GO:0010721 12133 106 66 1 1346 12 3 false 0.6278755409167747 0.6278755409167747 1.6785551446261856E-160 GTPase_binding GO:0051020 12133 137 66 2 1005 15 1 false 0.6281617777879941 0.6281617777879941 4.2154504665352884E-173 response_to_starvation GO:0042594 12133 104 66 1 2586 24 2 false 0.6282903375190645 0.6282903375190645 1.0260437683061592E-188 positive_regulation_of_peptidase_activity GO:0010952 12133 121 66 1 1041 8 3 false 0.6291890704447904 0.6291890704447904 8.90382030646545E-162 transmembrane_transport GO:0055085 12133 728 66 5 7606 56 2 false 0.6321604462106398 0.6321604462106398 0.0 cytoskeleton-dependent_intracellular_transport GO:0030705 12133 67 66 1 2454 36 2 false 0.6335265191902568 0.6335265191902568 6.842684271212845E-133 positive_regulation_of_protein_kinase_B_signaling_cascade GO:0051897 12133 58 66 1 495 8 3 false 0.6338037788370224 0.6338037788370224 3.926574524631079E-77 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 66 4 3447 21 2 false 0.6347499424263168 0.6347499424263168 0.0 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 66 3 1088 11 3 false 0.6354792890374407 0.6354792890374407 1.7563474810306042E-279 lymphocyte_proliferation GO:0046651 12133 160 66 1 404 2 2 false 0.6358253691373246 0.6358253691373246 3.946230420659752E-117 mRNA_3'-UTR_binding GO:0003730 12133 20 66 1 91 4 1 false 0.6364553049946136 0.6364553049946136 1.5304206568397613E-20 cellular_response_to_extracellular_stimulus GO:0031668 12133 130 66 1 4577 35 4 false 0.6366219380195148 0.6366219380195148 5.475296256672863E-256 cation_binding GO:0043169 12133 2758 66 17 4448 28 1 false 0.6366262097025167 0.6366262097025167 0.0 transmission_of_nerve_impulse GO:0019226 12133 586 66 4 4105 30 3 false 0.6384751385500826 0.6384751385500826 0.0 positive_regulation_of_cell_projection_organization GO:0031346 12133 123 66 1 1031 8 3 false 0.6394118786062958 0.6394118786062958 5.58920875093251E-163 cell_division GO:0051301 12133 438 66 3 7541 56 1 false 0.6395786472397385 0.6395786472397385 0.0 sex_differentiation GO:0007548 12133 202 66 2 340 3 1 false 0.6399123360921382 0.6399123360921382 4.342696063294865E-99 neural_crest_cell_differentiation GO:0014033 12133 47 66 1 118 2 1 false 0.6400115891641239 0.6400115891641239 4.6953210733755704E-34 regulation_of_cell_activation GO:0050865 12133 303 66 2 6351 45 2 false 0.6403286296952868 0.6403286296952868 0.0 generation_of_precursor_metabolites_and_energy GO:0006091 12133 364 66 3 7256 65 1 false 0.6403880636298164 0.6403880636298164 0.0 chromosome_segregation GO:0007059 12133 136 66 1 7541 56 1 false 0.6404611359386871 0.6404611359386871 5.819868354628029E-295 Fc_receptor_mediated_stimulatory_signaling_pathway GO:0002431 12133 76 66 3 178 7 1 false 0.6406883882979189 0.6406883882979189 2.9073989409378337E-52 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 66 11 645 12 1 false 0.6407002436273562 0.6407002436273562 7.3138241320053254E-93 chromosome,_centromeric_region GO:0000775 12133 148 66 1 512 3 1 false 0.6415277497983706 0.6415277497983706 5.05623540709124E-133 regulation_of_protein_localization GO:0032880 12133 349 66 5 2148 33 2 false 0.6418486315486612 0.6418486315486612 0.0 regulation_of_cell_cycle_arrest GO:0071156 12133 89 66 1 481 5 2 false 0.6421997369273024 0.6421997369273024 1.91357850692127E-99 clathrin-coated_vesicle GO:0030136 12133 162 66 2 202 2 1 false 0.6423821486626322 0.6423821486626322 3.1333299685548734E-43 positive_regulation_of_cell_adhesion GO:0045785 12133 114 66 1 3174 28 3 false 0.6425067630750989 0.6425067630750989 1.3009596629773978E-212 anatomical_structure_development GO:0048856 12133 3099 66 19 3447 21 1 false 0.642659600556488 0.642659600556488 0.0 regulation_of_mRNA_splicing,_via_spliceosome GO:0048024 12133 32 66 2 231 15 3 false 0.6443603709743109 0.6443603709743109 5.789429371590664E-40 chromatin_binding GO:0003682 12133 309 66 2 8962 63 1 false 0.6446892147406085 0.6446892147406085 0.0 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 66 6 1813 21 1 false 0.6447543619412492 0.6447543619412492 0.0 positive_regulation_of_Wnt_receptor_signaling_pathway GO:0030177 12133 62 66 1 935 15 3 false 0.645563641955482 0.645563641955482 1.606337900726139E-98 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 66 4 1393 16 3 false 0.6457419724742474 0.6457419724742474 0.0 potassium_ion_transmembrane_transporter_activity GO:0015079 12133 92 66 1 315 3 3 false 0.6466007920841661 0.6466007920841661 4.7759735730125735E-82 response_to_type_I_interferon GO:0034340 12133 60 66 1 900 15 2 false 0.6477169416114665 0.6477169416114665 3.4610416117449214E-95 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 66 3 365 3 1 false 0.6480767053619656 0.6480767053619656 4.982755146780477E-62 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 66 32 5532 58 4 false 0.6482000680896953 0.6482000680896953 0.0 exocytosis GO:0006887 12133 246 66 2 1184 10 2 false 0.6482679490978474 0.6482679490978474 6.194714731116342E-262 RNA_localization GO:0006403 12133 131 66 2 1642 27 1 false 0.6483784614146574 0.6483784614146574 1.0675246049472868E-197 nuclear_matrix GO:0016363 12133 81 66 1 2767 35 2 false 0.6488040636968819 0.6488040636968819 2.9785824972298125E-158 nitric-oxide_synthase_activity GO:0004517 12133 37 66 1 57 1 1 false 0.6491228070175405 0.6491228070175405 8.262622213776184E-16 response_to_steroid_hormone_stimulus GO:0048545 12133 272 66 2 938 7 3 false 0.6498286336161865 0.6498286336161865 1.788442659003846E-244 T_cell_costimulation GO:0031295 12133 59 66 1 145 2 2 false 0.6499042145593237 0.6499042145593237 4.1748509083178786E-42 regulation_of_proteolysis GO:0030162 12133 146 66 2 1822 27 2 false 0.6506081910941296 0.6506081910941296 4.197674460173735E-220 regulation_of_cell-substrate_adhesion GO:0010810 12133 96 66 1 325 3 2 false 0.651530082118267 0.651530082118267 4.496729814644984E-85 cell-substrate_adherens_junction_assembly GO:0007045 12133 45 66 1 69 1 2 false 0.6521739130434739 0.6521739130434739 4.3372108507464655E-19 positive_regulation_of_DNA_metabolic_process GO:0051054 12133 92 66 1 2322 26 4 false 0.6524781088782428 0.6524781088782428 1.6937907011714837E-167 T_cell_differentiation GO:0030217 12133 140 66 1 341 2 2 false 0.6532689322062997 0.6532689322062997 1.226864280824078E-99 small_conjugating_protein_ligase_activity GO:0019787 12133 335 66 9 351 9 1 false 0.6538467299157453 0.6538467299157453 5.577217121688537E-28 regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001242 12133 31 66 1 193 6 2 false 0.6555314495041179 0.6555314495041179 1.4758328099403201E-36 polyubiquitin_binding GO:0031593 12133 25 66 1 61 2 1 false 0.6557377049180477 0.6557377049180477 1.1367792653855182E-17 cell_growth GO:0016049 12133 299 66 2 7559 56 2 false 0.6560949618580918 0.6560949618580918 0.0 transmembrane_receptor_protein_kinase_activity GO:0019199 12133 102 66 1 1394 14 2 false 0.6566452856343366 0.6566452856343366 8.190780681106084E-158 regulation_of_endocytosis GO:0030100 12133 113 66 1 1437 13 3 false 0.6567728428170567 0.6567728428170567 3.3139638850760945E-171 epithelial_cell_migration GO:0010631 12133 130 66 3 185 4 2 false 0.6569925999719619 0.6569925999719619 1.9916445787710798E-48 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 66 6 1804 21 2 false 0.6585539781716006 0.6585539781716006 0.0 regulation_of_intracellular_protein_transport GO:0033157 12133 160 66 4 847 23 3 false 0.659078878625468 0.659078878625468 1.5386851760422239E-177 positive_regulation_of_endopeptidase_activity GO:0010950 12133 112 66 1 476 4 3 false 0.6593693397287839 0.6593693397287839 3.786215967470695E-112 negative_regulation_of_cellular_component_movement GO:0051271 12133 114 66 1 3032 28 3 false 0.6597155274881374 0.6597155274881374 2.6462769841807196E-210 regulation_of_blood_pressure GO:0008217 12133 117 66 1 2120 19 2 false 0.661547179553023 0.661547179553023 6.820682324461924E-196 regulation_of_lyase_activity GO:0051339 12133 117 66 1 1793 16 2 false 0.6618897463196547 0.6618897463196547 4.0773224530305873E-187 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 66 2 81 2 2 false 0.6620370370370483 0.6620370370370483 1.2278945146862784E-16 lymphocyte_differentiation GO:0030098 12133 203 66 1 485 2 2 false 0.6624265144415058 0.6624265144415058 1.747932496277033E-142 developmental_process_involved_in_reproduction GO:0003006 12133 340 66 3 3959 39 2 false 0.6635995285579647 0.6635995285579647 0.0 nucleobase-containing_compound_transport GO:0015931 12133 135 66 2 1584 26 2 false 0.664697942677494 0.664697942677494 1.0378441909200412E-199 negative_regulation_of_protein_kinase_activity GO:0006469 12133 163 66 2 1050 14 4 false 0.6650932460602628 0.6650932460602628 4.119509868513009E-196 developmental_maturation GO:0021700 12133 155 66 1 2776 19 1 false 0.6655630299229414 0.6655630299229414 7.129565011141826E-259 regulation_of_histone_modification GO:0031056 12133 77 66 1 1240 17 3 false 0.6661866844116591 0.6661866844116591 1.0351200557646026E-124 mRNA_stabilization GO:0048255 12133 22 66 1 33 1 2 false 0.6666666666666647 0.6666666666666647 5.166978132108427E-9 neurotrophin_TRK_receptor_binding GO:0005167 12133 6 66 1 9 1 1 false 0.6666666666666665 0.6666666666666665 0.011904761904761887 ferric_iron_transport GO:0015682 12133 24 66 1 36 1 2 false 0.6666666666666695 0.6666666666666695 7.989277111831545E-10 regulation_of_insulin_secretion GO:0050796 12133 121 66 2 148 2 2 false 0.6674020959734415 0.6674020959734415 3.4478322296397875E-30 response_to_peptide_hormone_stimulus GO:0043434 12133 313 66 3 619 6 2 false 0.6675869090812419 0.6675869090812419 1.4916788604957572E-185 synapse GO:0045202 12133 368 66 2 10701 66 1 false 0.6682120224869594 0.6682120224869594 0.0 regulation_of_protein_import_into_nucleus GO:0042306 12133 121 66 2 248 4 4 false 0.6705890490312445 0.6705890490312445 4.6955049394038436E-74 growth_factor_binding GO:0019838 12133 135 66 1 6397 52 1 false 0.6716343660620945 0.6716343660620945 1.7435678435075742E-283 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 66 1 183 2 2 false 0.6721311475409307 0.6721311475409307 1.0111677973178846E-53 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 66 1 197 5 3 false 0.6723442385669255 0.6723442385669255 3.777320475653026E-42 negative_regulation_of_cell_migration GO:0030336 12133 108 66 1 735 7 3 false 0.6728775934844134 0.6728775934844134 1.4353405807943923E-132 steroid_biosynthetic_process GO:0006694 12133 98 66 1 3573 40 3 false 0.6732784142244794 0.6732784142244794 2.291833143174281E-194 kinase_regulator_activity GO:0019207 12133 125 66 1 1851 16 3 false 0.6748385607764852 0.6748385607764852 5.123060762627793E-198 purine_nucleotide_metabolic_process GO:0006163 12133 1208 66 11 1337 12 2 false 0.6751048222271641 0.6751048222271641 1.5771526523631757E-183 Hsp90_protein_binding GO:0051879 12133 15 66 1 49 3 1 false 0.6752062527138514 0.6752062527138514 6.346866259278141E-13 mitochondrial_outer_membrane_permeabilization GO:0097345 12133 37 66 1 319 9 3 false 0.6752337458389231 0.6752337458389231 2.7662883808425E-49 response_to_interleukin-1 GO:0070555 12133 60 66 1 461 8 1 false 0.6752462841551072 0.6752462841551072 6.955751367016218E-77 regulation_of_cyclase_activity GO:0031279 12133 115 66 1 1700 16 2 false 0.6756251651270841 0.6756251651270841 4.764508019192963E-182 peptide_hormone_secretion GO:0030072 12133 153 66 2 186 2 2 false 0.6758500435920984 0.6758500435920984 2.2720406169547848E-37 cell_projection_organization GO:0030030 12133 744 66 5 7663 58 2 false 0.6760239718392743 0.6760239718392743 0.0 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 66 1 1054 12 3 false 0.6760454099669144 0.6760454099669144 5.573854633657796E-137 DNA_recombination GO:0006310 12133 190 66 2 791 9 1 false 0.6769869169878524 0.6769869169878524 1.2250789605162758E-188 morphogenesis_of_a_branching_structure GO:0001763 12133 169 66 1 4284 28 3 false 0.6771581097077928 0.6771581097077928 2.023740855196032E-308 membrane_invagination GO:0010324 12133 411 66 6 784 12 1 false 0.6778182010130525 0.6778182010130525 8.658368437912315E-235 transmembrane_receptor_protein_tyrosine_kinase_activity GO:0004714 12133 85 66 1 197 2 2 false 0.6780275562000746 0.6780275562000746 5.558033582657792E-58 cellular_protein_complex_assembly GO:0043623 12133 284 66 3 958 11 2 false 0.6793911384185722 0.6793911384185722 4.57678794545446E-252 detection_of_stimulus GO:0051606 12133 153 66 1 5200 38 1 false 0.6798526644426681 0.6798526644426681 5.428481844646795E-299 cyclic_nucleotide_biosynthetic_process GO:0009190 12133 151 66 1 348 2 2 false 0.6802477723675473 0.6802477723675473 8.533554981861938E-103 epithelial_cell_development GO:0002064 12133 164 66 1 1381 9 2 false 0.6805964330368932 0.6805964330368932 8.032286414365126E-218 Rho_GTPase_binding GO:0017048 12133 52 66 1 120 2 1 false 0.680952380952396 0.680952380952396 2.990284088371456E-35 adherens_junction_assembly GO:0034333 12133 52 66 1 165 3 2 false 0.6815039516820691 0.6815039516820691 3.3179738133462556E-44 endosomal_part GO:0044440 12133 257 66 2 7185 65 3 false 0.6816951074063318 0.6816951074063318 0.0 regulation_of_anatomical_structure_morphogenesis GO:0022603 12133 528 66 3 2074 13 2 false 0.6818123528011824 0.6818123528011824 0.0 regulation_of_cyclin-dependent_protein_serine/threonine_kinase_activity GO:0000079 12133 77 66 1 918 13 3 false 0.6823256753606565 0.6823256753606565 2.8017058584530626E-114 negative_regulation_of_cell_growth GO:0030308 12133 117 66 1 2621 25 4 false 0.6824259654173177 0.6824259654173177 6.020174158767381E-207 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 66 2 185 2 1 false 0.6831962397181021 0.6831962397181021 1.2806047113744547E-36 positive_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043280 12133 101 66 1 1376 15 3 false 0.6832389987485705 0.6832389987485705 4.055423334241229E-156 cellular_response_to_external_stimulus GO:0071496 12133 182 66 1 1046 6 1 false 0.6833530275284132 0.6833530275284132 3.4557864180082167E-209 protein_K63-linked_ubiquitination GO:0070534 12133 28 66 1 163 6 1 false 0.6834982628067048 0.6834982628067048 4.092462206953933E-32 cell-matrix_adhesion GO:0007160 12133 130 66 1 190 1 1 false 0.6842105263158172 0.6842105263158172 5.558763172566491E-51 transmembrane_transporter_activity GO:0022857 12133 544 66 3 904 5 2 false 0.6860033842593256 0.6860033842593256 4.222056161945909E-263 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 66 2 299 4 2 false 0.6862437079827545 0.6862437079827545 2.1331125641940734E-89 generation_of_neurons GO:0048699 12133 883 66 6 940 6 1 false 0.686353615110111 0.686353615110111 7.799501535546468E-93 signal_transducer_activity GO:0004871 12133 1070 66 8 3547 29 2 false 0.6863735808278582 0.6863735808278582 0.0 small_molecule_metabolic_process GO:0044281 12133 2423 66 15 2877 18 1 false 0.6869395023434857 0.6869395023434857 0.0 mRNA_3'-end_processing GO:0031124 12133 86 66 3 386 15 2 false 0.6872452663619362 0.6872452663619362 2.4694341980396157E-88 response_to_organic_nitrogen GO:0010243 12133 519 66 5 1787 19 3 false 0.6874257102134091 0.6874257102134091 0.0 fatty_acid_metabolic_process GO:0006631 12133 214 66 1 666 3 2 false 0.6880654093717447 0.6880654093717447 7.544095427296943E-181 DNA_catabolic_process GO:0006308 12133 66 66 1 2145 37 3 false 0.6884875598692586 0.6884875598692586 1.9973602853494904E-127 receptor_metabolic_process GO:0043112 12133 101 66 1 5613 64 1 false 0.6892389860801903 0.6892389860801903 4.997034842501505E-219 regulation_of_Ras_GTPase_activity GO:0032318 12133 179 66 2 357 4 2 false 0.6906616167594086 0.6906616167594086 8.083441090582102E-107 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 66 1 260 3 3 false 0.6915341101388329 0.6915341101388329 1.712440969539876E-70 metal_ion_binding GO:0046872 12133 2699 66 17 2758 17 1 false 0.6916343391126459 0.6916343391126459 2.6200760259069314E-123 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 66 1 574 4 3 false 0.691985244616269 0.691985244616269 1.1371703790830463E-140 positive_regulation_of_proteolysis GO:0045862 12133 69 66 1 1334 22 3 false 0.692095928164363 0.692095928164363 2.369917275782091E-117 cellular_response_to_type_I_interferon GO:0071357 12133 59 66 1 382 7 2 false 0.694114894836959 0.694114894836959 7.131731716015008E-71 response_to_salt_stress GO:0009651 12133 19 66 1 43 2 1 false 0.694352159468437 0.694352159468437 1.2492622608986976E-12 protein_phosphatase_binding GO:0019903 12133 75 66 1 108 1 1 false 0.694444444444449 0.694444444444449 1.6262935863243163E-28 negative_regulation_of_cell_motility GO:2000146 12133 110 66 1 800 8 4 false 0.6954678733356716 0.6954678733356716 1.883997981968334E-138 metanephros_development GO:0001656 12133 72 66 1 161 2 1 false 0.6959627329192206 0.6959627329192206 1.331701977621073E-47 female_gonad_development GO:0008585 12133 73 66 1 163 2 2 false 0.6966598500340033 0.6966598500340033 3.313368928641239E-48 negative_regulation_of_catabolic_process GO:0009895 12133 83 66 1 3124 44 3 false 0.6967409254188468 0.6967409254188468 1.0289413364876372E-165 cell_migration_involved_in_sprouting_angiogenesis GO:0002042 12133 22 66 1 68 3 2 false 0.6971027216856991 0.6971027216856991 2.4938962391792082E-18 organic_hydroxy_compound_metabolic_process GO:1901615 12133 279 66 2 7451 64 1 false 0.6978857648718426 0.6978857648718426 0.0 nucleotide-excision_repair GO:0006289 12133 78 66 1 368 5 1 false 0.6983196370800016 0.6983196370800016 5.504322769590107E-82 muscle_fiber_development GO:0048747 12133 93 66 1 133 1 1 false 0.6992481203007894 0.6992481203007894 6.346042881794858E-35 negative_regulation_of_locomotion GO:0040013 12133 129 66 1 3189 29 3 false 0.6996724802674856 0.6996724802674856 7.329512152442089E-234 aging GO:0007568 12133 170 66 1 2776 19 1 false 0.7002281600935971 0.7002281600935971 5.943091023043611E-277 polysome GO:0005844 12133 22 66 1 569 30 1 false 0.7032382498917463 0.7032382498917463 4.138788255326549E-40 antigen_processing_and_presentation_of_peptide_or_polysaccharide_antigen_via_MHC_class_II GO:0002504 12133 84 66 1 185 2 1 false 0.7032902467685117 0.7032902467685117 7.577866882274746E-55 regulation_of_gene_expression,_epigenetic GO:0040029 12133 120 66 1 2935 29 1 false 0.703748551820779 0.703748551820779 6.075348180017095E-217 GTP_binding GO:0005525 12133 292 66 2 1635 13 3 false 0.704598807184104 0.704598807184104 0.0 regulation_of_androgen_receptor_signaling_pathway GO:0060765 12133 21 66 1 81 4 2 false 0.7069043239929225 0.7069043239929225 7.333410898212426E-20 positive_regulation_of_cAMP_metabolic_process GO:0030816 12133 71 66 1 155 2 4 false 0.7079178885629959 0.7079178885629959 5.885583975701031E-46 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 66 1 3406 28 3 false 0.7082087567806525 0.7082087567806525 5.390613252169377E-261 protein_tetramerization GO:0051262 12133 76 66 1 288 4 1 false 0.7085939128620014 0.7085939128620014 1.240191410365077E-71 intracellular_ligand-gated_calcium_channel_activity GO:0005218 12133 22 66 1 31 1 2 false 0.7096774193548394 0.7096774193548394 4.960299006824101E-8 macroautophagy GO:0016236 12133 49 66 1 146 3 2 false 0.7098094788222307 0.7098094788222307 4.979783011193841E-40 adenylate_cyclase_activity GO:0004016 12133 103 66 1 145 1 3 false 0.710344827586197 0.710344827586197 1.7288474062512548E-37 negative_regulation_of_organelle_organization GO:0010639 12133 168 66 1 2125 15 3 false 0.7105141117061012 0.7105141117061012 2.2467097914760192E-254 cell_junction GO:0030054 12133 588 66 3 10701 66 1 false 0.7108283431192886 0.7108283431192886 0.0 ncRNA_metabolic_process GO:0034660 12133 258 66 3 3294 46 1 false 0.711255660539613 0.711255660539613 0.0 type_I_interferon-mediated_signaling_pathway GO:0060337 12133 59 66 1 318 6 2 false 0.7112590031421937 0.7112590031421937 9.855417365479732E-66 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 66 2 2943 29 3 false 0.7115049916823315 0.7115049916823315 0.0 mitochondrion GO:0005739 12133 1138 66 8 8213 66 2 false 0.712016888715221 0.712016888715221 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 66 1 158 2 2 false 0.7121664113520566 0.7121664113520566 6.794891168245598E-47 regulation_of_lymphocyte_proliferation GO:0050670 12133 127 66 1 274 2 3 false 0.7130825378998947 0.7130825378998947 1.4165790688232408E-81 positive_regulation_of_response_to_external_stimulus GO:0032103 12133 126 66 1 1783 17 3 false 0.7139943525625906 0.7139943525625906 4.953245093659787E-197 ribonucleotide_metabolic_process GO:0009259 12133 1202 66 11 1318 12 2 false 0.7144464300892757 0.7144464300892757 7.680938106405399E-170 localization_of_cell GO:0051674 12133 785 66 8 3467 40 1 false 0.714965569434701 0.714965569434701 0.0 response_to_carbohydrate_stimulus GO:0009743 12133 116 66 1 1822 19 2 false 0.7152974204043914 0.7152974204043914 8.541992370523989E-187 nuclear_periphery GO:0034399 12133 97 66 1 2767 35 2 false 0.7154544276160071 0.7154544276160071 7.041791399430774E-182 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 66 12 5657 56 2 false 0.7162398189220991 0.7162398189220991 0.0 nuclear_export GO:0051168 12133 116 66 3 688 21 2 false 0.7165108983865404 0.7165108983865404 6.892155989004194E-135 regulation_of_nitric-oxide_synthase_activity GO:0050999 12133 33 66 1 46 1 2 false 0.7173913043478244 0.7173913043478244 9.826442349658767E-12 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 66 4 1211 12 2 false 0.7185144646978987 0.7185144646978987 0.0 divalent_metal_ion_transport GO:0070838 12133 237 66 2 455 4 2 false 0.7190391507240332 0.7190391507240332 4.2718300435394164E-136 peptidyl-tyrosine_phosphorylation GO:0018108 12133 191 66 2 1195 15 2 false 0.7190999186603559 0.7190999186603559 2.9198379950600046E-227 lymphocyte_activation GO:0046649 12133 403 66 2 475 2 1 false 0.7195469686876439 0.7195469686876439 3.3805466364584557E-87 Golgi_apparatus_part GO:0044431 12133 406 66 3 7185 65 3 false 0.719560324000236 0.719560324000236 0.0 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 66 1 134 2 2 false 0.7211311861743613 0.7211311861743613 8.460684206886756E-40 phospholipase_activity GO:0004620 12133 159 66 2 187 2 1 false 0.7222701397274089 0.7222701397274089 6.26556876547974E-34 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 66 2 1631 19 2 false 0.7241640902455793 0.7241640902455793 3.3133814045702313E-271 negative_regulation_of_gene_expression GO:0010629 12133 817 66 9 3906 49 3 false 0.7245176844081581 0.7245176844081581 0.0 RNA_3'-end_processing GO:0031123 12133 98 66 3 601 22 1 false 0.7250850983014969 0.7250850983014969 1.9130441150898719E-115 nuclear_hormone_receptor_binding GO:0035257 12133 104 66 2 122 2 1 false 0.7256469313101672 0.7256469313101672 6.677251530520905E-22 regulation_of_MAPK_cascade GO:0043408 12133 429 66 8 701 14 2 false 0.7265889558140339 0.7265889558140339 1.5434745144062482E-202 amide_binding GO:0033218 12133 182 66 1 8962 63 1 false 0.7266794869723391 0.7266794869723391 0.0 amide_transport GO:0042886 12133 167 66 2 2393 36 2 false 0.7285860613730359 0.7285860613730359 2.949417857518552E-262 positive_regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030804 12133 75 66 1 157 2 4 false 0.728809407153281 0.728809407153281 1.0054402594300752E-46 mitotic_cell_cycle GO:0000278 12133 625 66 7 1295 16 1 false 0.7294322776498224 0.7294322776498224 0.0 regulation_of_ryanodine-sensitive_calcium-release_channel_activity GO:0060314 12133 18 66 1 38 2 3 false 0.729729729729729 0.729729729729729 2.978140395000689E-11 mRNA_transport GO:0051028 12133 106 66 2 124 2 1 false 0.7297403619197234 0.7297403619197234 4.872659948511352E-22 regulation_of_cell_proliferation GO:0042127 12133 999 66 6 6358 45 2 false 0.7313123745967263 0.7313123745967263 0.0 erythrocyte_homeostasis GO:0034101 12133 95 66 2 111 2 1 false 0.7313677313677038 0.7313677313677038 1.225965890705918E-19 regulation_of_hormone_levels GO:0010817 12133 272 66 2 2082 19 1 false 0.7316907279155123 0.7316907279155123 0.0 cation_channel_complex GO:0034703 12133 90 66 1 123 1 1 false 0.7317073170731456 0.7317073170731456 1.062129123485266E-30 contractile_fiber_part GO:0044449 12133 144 66 1 7199 65 3 false 0.7326758778488025 0.7326758778488025 8.364096489052254E-306 NAD-dependent_histone_deacetylase_activity_(H3-K14_specific) GO:0032041 12133 11 66 1 15 1 2 false 0.7333333333333318 0.7333333333333318 7.326007326007312E-4 NAD-dependent_histone_deacetylase_activity_(H4-K16_specific) GO:0046970 12133 11 66 1 15 1 2 false 0.7333333333333318 0.7333333333333318 7.326007326007312E-4 central_nervous_system_development GO:0007417 12133 571 66 3 2686 17 2 false 0.7342442178170678 0.7342442178170678 0.0 muscle_system_process GO:0003012 12133 252 66 1 1272 6 1 false 0.7349004664727328 0.7349004664727328 3.711105192357829E-274 purine-containing_compound_metabolic_process GO:0072521 12133 1232 66 11 5323 54 5 false 0.7358297568638411 0.7358297568638411 0.0 ubiquitin_binding GO:0043130 12133 61 66 2 71 2 1 false 0.7364185110663888 0.7364185110663888 2.1657301017057942E-12 poly-purine_tract_binding GO:0070717 12133 14 66 1 40 3 1 false 0.7368421052631625 0.7368421052631625 4.309057712047628E-11 secretory_granule GO:0030141 12133 202 66 1 712 4 1 false 0.7376352700755602 0.7376352700755602 1.1363731817938802E-183 regulation_of_GTPase_activity GO:0043087 12133 277 66 2 1145 10 3 false 0.7385106089719429 0.7385106089719429 2.6919247726004267E-274 cellular_response_to_metal_ion GO:0071248 12133 69 66 1 192 3 2 false 0.7394073780656771 0.7394073780656771 5.854997654482861E-54 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 66 12 207 12 1 false 0.7396233510169027 0.7396233510169027 3.3148479610294504E-10 epithelial_tube_formation GO:0072175 12133 91 66 1 252 3 2 false 0.7409827357237037 0.7409827357237037 5.018785577883075E-71 enzyme_regulator_activity GO:0030234 12133 771 66 4 10257 66 3 false 0.741256723880632 0.741256723880632 0.0 protein_tyrosine_kinase_activity GO:0004713 12133 180 66 2 1014 14 1 false 0.7412793409331171 0.7412793409331171 3.660578992202259E-205 cytokinesis GO:0000910 12133 111 66 1 1047 12 2 false 0.7413705353391059 0.7413705353391059 4.556333438415199E-153 DNA-dependent_DNA_replication GO:0006261 12133 93 66 1 257 3 1 false 0.7418731403066932 0.7418731403066932 1.72483826119428E-72 erythrocyte_differentiation GO:0030218 12133 88 66 1 243 3 2 false 0.7423054891934331 0.7423054891934331 1.540826297870933E-68 cyclin-dependent_protein_kinase_activity GO:0097472 12133 105 66 1 1997 25 2 false 0.7430046723123713 0.7430046723123713 5.046200754373572E-178 muscle_cell_development GO:0055001 12133 141 66 1 1322 12 2 false 0.7431871891380445 0.7431871891380445 3.535972780015326E-194 positive_regulation_of_Ras_GTPase_activity GO:0032320 12133 131 66 1 266 2 2 false 0.7433678535962488 0.7433678535962488 1.778046339762686E-79 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 66 5 1192 23 2 false 0.7434283283195974 0.7434283283195974 5.168872172755415E-294 single-multicellular_organism_process GO:0044707 12133 4095 66 27 8057 57 2 false 0.7443166445676852 0.7443166445676852 0.0 carboxylic_acid_transport GO:0046942 12133 137 66 1 184 1 2 false 0.7445652173913182 0.7445652173913182 5.817887468260403E-45 carboxylic_acid_binding GO:0031406 12133 186 66 1 2280 16 1 false 0.7449476719853563 0.7449476719853563 4.771798836819993E-279 development_of_primary_female_sexual_characteristics GO:0046545 12133 88 66 1 178 2 2 false 0.7457627118644479 0.7457627118644479 4.419703906638309E-53 regulation_of_adenylate_cyclase_activity GO:0045761 12133 103 66 1 138 1 4 false 0.7463768115942113 0.7463768115942113 1.4792034822830027E-33 response_to_oxygen-containing_compound GO:1901700 12133 864 66 7 2369 22 1 false 0.7470855363674191 0.7470855363674191 0.0 single-organism_carbohydrate_metabolic_process GO:0044723 12133 385 66 1 515 1 1 false 0.7475728155339276 0.7475728155339276 1.0653300741927565E-125 epithelium_development GO:0060429 12133 627 66 4 1132 8 1 false 0.747728012553911 0.747728012553911 0.0 regulation_of_translation GO:0006417 12133 210 66 2 3605 45 4 false 0.7478366462666068 0.7478366462666068 0.0 extrinsic_apoptotic_signaling_pathway_via_death_domain_receptors GO:0008625 12133 28 66 1 77 3 1 false 0.7481339712918513 0.7481339712918513 1.2774080507019578E-21 mammary_gland_development GO:0030879 12133 125 66 1 251 2 1 false 0.7490039840637394 0.7490039840637394 5.503793662567663E-75 regulation_of_actin_filament-based_process GO:0032970 12133 192 66 1 6365 45 2 false 0.7492198799876512 0.7492198799876512 0.0 neurological_system_process GO:0050877 12133 894 66 4 1272 6 1 false 0.7499074442837523 0.7499074442837523 0.0 maturation_of_SSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000462 12133 7 66 2 8 2 1 false 0.7500000000000001 0.7500000000000001 0.12499999999999997 DNA_topoisomerase_II_activity GO:0061505 12133 6 66 1 8 1 1 false 0.7500000000000001 0.7500000000000001 0.035714285714285705 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 66 9 2528 23 3 false 0.7505890253813006 0.7505890253813006 0.0 cell_cortex GO:0005938 12133 175 66 1 6402 50 2 false 0.7512219256583759 0.7512219256583759 0.0 regulation_of_JAK-STAT_cascade GO:0046425 12133 66 66 1 656 13 2 false 0.7514172219231002 0.7514172219231002 1.950107224419378E-92 cellular_response_to_hormone_stimulus GO:0032870 12133 384 66 4 1510 19 3 false 0.7522450626434276 0.7522450626434276 0.0 protein_maturation GO:0051604 12133 123 66 1 5551 62 2 false 0.7526703633620704 0.7526703633620704 1.3126924681575497E-255 cell_chemotaxis GO:0060326 12133 132 66 1 2155 22 3 false 0.7528214492966855 0.7528214492966855 6.49351277121459E-215 divalent_inorganic_cation_homeostasis GO:0072507 12133 223 66 2 330 3 1 false 0.7534829726578197 0.7534829726578197 1.0852171628360601E-89 single_fertilization GO:0007338 12133 49 66 1 65 1 1 false 0.753846153846139 0.753846153846139 1.543100485620412E-15 contractile_fiber GO:0043292 12133 159 66 1 6670 58 2 false 0.7547414043710761 0.7547414043710761 0.0 regulation_of_myeloid_cell_differentiation GO:0045637 12133 124 66 1 1656 18 4 false 0.7554880615409154 0.7554880615409154 1.1641273300011644E-190 negative_regulation_of_MAP_kinase_activity GO:0043407 12133 62 66 1 343 7 4 false 0.7556934707590262 0.7556934707590262 7.269028156110723E-70 cell_morphogenesis GO:0000902 12133 766 66 5 810 5 1 false 0.7558047114821957 0.7558047114821957 9.285456073507826E-74 striated_muscle_cell_differentiation GO:0051146 12133 203 66 3 267 4 1 false 0.7564245379381367 0.7564245379381367 2.4098375851666058E-63 centrosome GO:0005813 12133 327 66 3 3226 38 2 false 0.7565431033659584 0.7565431033659584 0.0 transcription_cofactor_activity GO:0003712 12133 456 66 5 482 5 2 false 0.7569583202776928 0.7569583202776928 1.3948726648763881E-43 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_II GO:0002495 12133 83 66 1 164 2 2 false 0.7575938949573486 0.7575938949573486 6.958070805209033E-49 intrinsic_to_plasma_membrane GO:0031226 12133 826 66 2 2695 8 2 false 0.7577245963695353 0.7577245963695353 0.0 cell-cell_junction GO:0005911 12133 222 66 1 588 3 1 false 0.7595845962040114 0.7595845962040114 1.5852162200644845E-168 neurogenesis GO:0022008 12133 940 66 6 2425 18 2 false 0.7600033391617892 0.7600033391617892 0.0 regulation_of_secretion GO:0051046 12133 367 66 2 1193 8 2 false 0.7603978636735971 0.7603978636735971 6.7239E-319 covalent_chromatin_modification GO:0016569 12133 312 66 2 458 3 1 false 0.7604489422941352 0.7604489422941352 7.826311589520491E-124 organelle_fission GO:0048285 12133 351 66 2 2031 15 1 false 0.7610013143725227 0.7610013143725227 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 66 26 2805 26 1 false 0.7622941837677637 0.7622941837677637 1.0460685646312495E-69 double-stranded_RNA_binding GO:0003725 12133 42 66 1 763 25 1 false 0.7628099930258814 0.7628099930258814 3.809412344480898E-70 response_to_amphetamine GO:0001975 12133 26 66 1 34 1 1 false 0.7647058823529387 0.7647058823529387 5.507759221035346E-8 hormone_transport GO:0009914 12133 189 66 2 2386 34 2 false 0.7648787587169381 0.7648787587169381 4.465203217560849E-286 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 66 1 1198 22 4 false 0.7666276568917241 0.7666276568917241 2.335035261625238E-122 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 66 1 269 3 2 false 0.7666340200753399 0.7666340200753399 3.613555574654199E-77 negative_regulation_of_phosphorylation GO:0042326 12133 215 66 2 1463 18 3 false 0.7672074802826392 0.7672074802826392 2.1310280163327356E-264 positive_regulation_of_immune_effector_process GO:0002699 12133 87 66 1 706 11 3 false 0.7672235002787832 0.7672235002787832 7.573271162497966E-114 vascular_process_in_circulatory_system GO:0003018 12133 118 66 1 307 3 1 false 0.7680995354300565 0.7680995354300565 3.250495259622763E-88 viral_genome_replication GO:0019079 12133 55 66 2 557 27 2 false 0.7683918403790739 0.7683918403790739 1.9020892479615726E-77 negative_regulation_of_protein_phosphorylation GO:0001933 12133 204 66 2 1311 17 4 false 0.7688311170377143 0.7688311170377143 2.3779440904857207E-245 negative_regulation_of_immune_system_process GO:0002683 12133 144 66 1 3524 35 3 false 0.7694935741794873 0.7694935741794873 1.8096661454151343E-260 male_gonad_development GO:0008584 12133 84 66 1 162 2 2 false 0.7697262479870297 0.7697262479870297 3.0520910486495067E-48 response_to_lipopolysaccharide GO:0032496 12133 183 66 1 970 7 3 false 0.769737227005298 0.769737227005298 3.000578332161695E-203 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_II GO:0019886 12133 80 66 1 154 2 2 false 0.7707325354383334 0.7707325354383334 7.662175327238918E-46 regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010769 12133 167 66 1 879 7 3 false 0.7724951125703547 0.7724951125703547 7.212819447877608E-185 plasma_membrane_part GO:0044459 12133 1329 66 7 10213 66 3 false 0.7726595734991596 0.7726595734991596 0.0 organic_hydroxy_compound_transport GO:0015850 12133 103 66 1 2569 36 2 false 0.7731430166746229 0.7731430166746229 4.89938384254503E-187 peptide_transport GO:0015833 12133 165 66 2 1580 26 2 false 0.7733375055099344 0.7733375055099344 6.47320563865109E-229 DNA_methylation_or_demethylation GO:0044728 12133 48 66 1 62 1 1 false 0.7741935483871082 0.7741935483871082 3.438909653668478E-14 nucleotidyltransferase_activity GO:0016779 12133 123 66 1 1304 15 1 false 0.7756563187383847 0.7756563187383847 3.0641101871346933E-176 cell-substrate_junction_assembly GO:0007044 12133 62 66 1 159 3 1 false 0.7757085549905013 0.7757085549905013 1.0273123292116476E-45 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 66 2 185 2 1 false 0.7757344300823621 0.7757344300823621 5.464989090238489E-29 developmental_growth GO:0048589 12133 223 66 1 2952 19 2 false 0.7762352062349083 0.7762352062349083 0.0 protein_kinase_binding GO:0019901 12133 341 66 7 384 8 1 false 0.7777125014318459 0.7777125014318459 5.20098898434574E-58 clathrin-sculpted_gamma-aminobutyric_acid_transport_vesicle GO:0061200 12133 7 66 1 9 1 1 false 0.7777777777777775 0.7777777777777775 0.027777777777777755 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 66 1 90 1 3 false 0.7777777777777884 0.7777777777777884 1.9615250672171495E-20 GTP_metabolic_process GO:0046039 12133 625 66 5 1193 11 3 false 0.7778491488122196 0.7778491488122196 0.0 DNA-dependent_ATPase_activity GO:0008094 12133 71 66 1 228 4 1 false 0.7778608998293051 0.7778608998293051 6.772142656773899E-61 multicellular_organismal_development GO:0007275 12133 3069 66 19 4373 29 2 false 0.7780657678648882 0.7780657678648882 0.0 neuron_part GO:0097458 12133 612 66 3 9983 66 1 false 0.7787375032222379 0.7787375032222379 0.0 microtubule-based_process GO:0007017 12133 378 66 2 7541 56 1 false 0.7790657034209212 0.7790657034209212 0.0 ubiquitin_thiolesterase_activity GO:0004221 12133 67 66 1 86 1 1 false 0.7790697674418556 0.7790697674418556 1.8312273425292562E-19 phospholipid_binding GO:0005543 12133 403 66 2 2392 16 2 false 0.7793975820790606 0.7793975820790606 0.0 regulation_of_ion_transport GO:0043269 12133 307 66 2 1393 12 2 false 0.7798097291761402 0.7798097291761402 3.368915E-318 regulation_of_mononuclear_cell_proliferation GO:0032944 12133 128 66 1 164 1 2 false 0.780487804878083 0.780487804878083 4.363818297439258E-37 cellular_membrane_fusion GO:0006944 12133 93 66 1 786 12 2 false 0.7818361358654822 0.7818361358654822 1.7836379235146202E-123 cytoplasmic_sequestering_of_transcription_factor GO:0042994 12133 20 66 1 38 2 2 false 0.7823613086771004 0.7823613086771004 2.978140395000689E-11 cell-cell_adhesion GO:0016337 12133 284 66 1 712 3 1 false 0.7833925946997738 0.7833925946997738 3.547957392630754E-207 growth GO:0040007 12133 646 66 3 10446 66 1 false 0.7838002752508728 0.7838002752508728 0.0 negative_regulation_of_protein_serine/threonine_kinase_activity GO:0071901 12133 98 66 1 757 11 3 false 0.7847489010422162 0.7847489010422162 4.731915708065017E-126 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 66 2 630 7 2 false 0.7848638683231026 0.7848638683231026 4.4826406352842784E-178 protein_kinase_regulator_activity GO:0019887 12133 106 66 1 1026 14 3 false 0.7849760520925402 0.7849760520925402 2.0818014646962408E-147 cAMP_metabolic_process GO:0046058 12133 143 66 1 1194 12 2 false 0.7852704627858882 0.7852704627858882 2.6525041284959264E-189 protein_modification_by_small_protein_removal GO:0070646 12133 77 66 1 645 12 1 false 0.7855324830090455 0.7855324830090455 7.565398504158586E-102 cell_projection GO:0042995 12133 976 66 5 9983 66 1 false 0.7861591529047682 0.7861591529047682 0.0 repressing_transcription_factor_binding GO:0070491 12133 207 66 2 715 9 1 false 0.7864416191213939 0.7864416191213939 4.3536836236667346E-186 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 66 4 7293 54 3 false 0.7866382181592239 0.7866382181592239 0.0 glycogen_metabolic_process GO:0005977 12133 58 66 1 145 3 2 false 0.7870046620045836 0.7870046620045836 6.156136085146564E-42 regulation_of_neuron_projection_development GO:0010975 12133 182 66 1 686 5 3 false 0.7870713495187339 0.7870713495187339 1.2648422067158072E-171 tight_junction_assembly GO:0070830 12133 31 66 1 58 2 2 false 0.7876588021778664 0.7876588021778664 3.809192954277456E-17 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 66 11 1218 11 2 false 0.7879313492351829 0.7879313492351829 3.12960829510125E-54 neurotransmitter_transport GO:0006836 12133 103 66 1 2323 34 1 false 0.7884497802965942 0.7884497802965942 1.9477606184121316E-182 release_of_sequestered_calcium_ion_into_cytosol GO:0051209 12133 56 66 1 71 1 2 false 0.7887323943661926 0.7887323943661926 1.0932134464693268E-15 embryonic_epithelial_tube_formation GO:0001838 12133 90 66 1 114 1 2 false 0.789473684210531 0.789473684210531 3.624094545378908E-25 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 66 1 3297 32 3 false 0.7895730307911726 0.7895730307911726 4.623981712175632E-272 B_cell_homeostasis GO:0001782 12133 23 66 1 43 2 1 false 0.7895902547065357 0.7895902547065357 1.0410518840822442E-12 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 66 1 163 2 1 false 0.7898204953418904 0.7898204953418904 2.2957799692832176E-48 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 66 9 1225 10 2 false 0.7911452883565638 0.7911452883565638 5.928244845001387E-155 development_of_primary_male_sexual_characteristics GO:0046546 12133 97 66 1 179 2 2 false 0.7915385098235898 0.7915385098235898 4.0970386268467766E-53 chromatin_organization GO:0006325 12133 539 66 3 689 4 1 false 0.7918358220602055 0.7918358220602055 4.375882251809235E-156 membrane_fusion GO:0061025 12133 96 66 1 787 12 1 false 0.7925437692625774 0.7925437692625774 4.051495195188967E-126 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 66 1 116 2 3 false 0.7934032983508316 0.7934032983508316 2.4978330889301296E-34 GTPase_activity GO:0003924 12133 612 66 5 1061 10 2 false 0.7934760726869763 0.7934760726869763 4.702100395E-313 regulation_of_Rho_GTPase_activity GO:0032319 12133 95 66 1 233 3 2 false 0.7940875167455431 0.7940875167455431 7.3761210037366725E-68 lyase_activity GO:0016829 12133 230 66 1 4901 33 1 false 0.7963820256245753 0.7963820256245753 0.0 regulation_of_calcium_ion_transport GO:0051924 12133 112 66 1 273 3 2 false 0.7964635754953671 0.7964635754953671 1.1179640912599917E-79 glucan_metabolic_process GO:0044042 12133 59 66 1 74 1 1 false 0.7972972972973 0.7972972972973 5.482425634220572E-16 Rho_protein_signal_transduction GO:0007266 12133 178 66 2 365 5 1 false 0.7984294046369713 0.7984294046369713 3.561371803691081E-109 peptidyl-serine_phosphorylation GO:0018105 12133 121 66 1 1201 15 2 false 0.7986643105594622 0.7986643105594622 1.0029038835537004E-169 ligand-gated_ion_channel_activity GO:0015276 12133 118 66 1 286 3 3 false 0.79881082594204 0.79881082594204 1.3590920268081467E-83 methylation GO:0032259 12133 195 66 1 8027 65 1 false 0.7991162464971908 0.7991162464971908 0.0 spindle_assembly_checkpoint GO:0071173 12133 36 66 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 NAD-dependent_histone_deacetylase_activity_(H3-K18_specific) GO:0097372 12133 12 66 1 15 1 2 false 0.8000000000000007 0.8000000000000007 0.002197802197802196 regulation_of_cAMP_biosynthetic_process GO:0030817 12133 124 66 1 155 1 4 false 0.8000000000000121 0.8000000000000121 2.5860077232155615E-33 cyclin-dependent_protein_serine/threonine_kinase_activity GO:0004693 12133 105 66 1 709 10 2 false 0.8009014265057286 0.8009014265057286 1.7307728384071896E-128 U12-type_spliceosomal_complex GO:0005689 12133 24 66 1 150 9 1 false 0.8014826537910844 0.8014826537910844 2.5760759444825708E-28 activation_of_cysteine-type_endopeptidase_activity GO:0097202 12133 85 66 1 106 1 1 false 0.801886792452837 0.801886792452837 1.25561322378657E-22 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 66 2 442 5 3 false 0.8024034376157358 0.8024034376157358 2.4953498472018727E-132 regulation_of_lipid_metabolic_process GO:0019216 12133 182 66 1 4352 38 2 false 0.8041550230228003 0.8041550230228003 0.0 organelle_membrane GO:0031090 12133 1619 66 9 9319 64 3 false 0.8046660341142485 0.8046660341142485 0.0 positive_regulation_of_leukocyte_activation GO:0002696 12133 206 66 2 756 10 4 false 0.8047584242030803 0.8047584242030803 1.5163059036704027E-191 chromosome_organization GO:0051276 12133 689 66 4 2031 15 1 false 0.8052331762938001 0.8052331762938001 0.0 response_to_external_stimulus GO:0009605 12133 1046 66 6 5200 38 1 false 0.8054018167896333 0.8054018167896333 0.0 microtubule_organizing_center GO:0005815 12133 413 66 3 1076 10 2 false 0.8064316006166652 0.8064316006166652 2.6476518998275E-310 regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0060828 12133 108 66 1 193 2 2 false 0.8073186528496898 0.8073186528496898 5.446526497036233E-57 positive_regulation_of_ERK1_and_ERK2_cascade GO:0070374 12133 73 66 1 350 7 3 false 0.8086109339078915 0.8086109339078915 2.793376924439548E-77 response_to_wounding GO:0009611 12133 905 66 7 2540 24 1 false 0.80864051716973 0.80864051716973 0.0 cellular_carbohydrate_metabolic_process GO:0044262 12133 183 66 1 7315 65 2 false 0.808742872439284 0.808742872439284 0.0 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 66 10 4456 46 4 false 0.8093042877388454 0.8093042877388454 0.0 cell-cell_signaling GO:0007267 12133 859 66 5 3969 30 2 false 0.8100036382099514 0.8100036382099514 0.0 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 66 6 1546 17 3 false 0.8100978298255292 0.8100978298255292 0.0 cellular_divalent_inorganic_cation_homeostasis GO:0072503 12133 214 66 2 297 3 2 false 0.810259489072926 0.810259489072926 7.435405484383431E-76 T_cell_homeostasis GO:0043029 12133 24 66 1 43 2 1 false 0.8106312292358822 0.8106312292358822 1.2492622608986976E-12 cellular_lipid_catabolic_process GO:0044242 12133 105 66 1 2404 37 3 false 0.8108466024849151 0.8108466024849151 1.0885633436927589E-186 negative_regulation_of_growth GO:0045926 12133 169 66 1 2922 28 3 false 0.8129073781997437 0.8129073781997437 1.2080528965902671E-279 insulin_secretion GO:0030073 12133 138 66 2 153 2 1 false 0.8129514963879341 0.8129514963879341 4.508804313440429E-21 ribosome_biogenesis GO:0042254 12133 144 66 3 243 6 1 false 0.8132674621603131 0.8132674621603131 8.984879194471426E-71 PML_body GO:0016605 12133 77 66 1 272 5 1 false 0.8133881522239628 0.8133881522239628 7.662735942565743E-70 secretion_by_cell GO:0032940 12133 578 66 3 7547 56 3 false 0.813674480183832 0.813674480183832 0.0 protein-DNA_complex GO:0032993 12133 110 66 1 3462 52 1 false 0.815801174729933 0.815801174729933 4.3156565695482125E-211 regulation_of_cAMP_metabolic_process GO:0030814 12133 133 66 1 465 5 3 false 0.8160689993325698 0.8160689993325698 3.255746313776628E-120 heart_process GO:0003015 12133 132 66 1 307 3 1 false 0.8161457139057068 0.8161457139057068 1.7124819377000923E-90 heart_contraction GO:0060047 12133 132 66 1 307 3 2 false 0.8161457139057068 0.8161457139057068 1.7124819377000923E-90 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 66 10 4582 47 3 false 0.8177964833508982 0.8177964833508982 0.0 regulation_of_GTP_catabolic_process GO:0033124 12133 279 66 2 642 6 3 false 0.8178584409394867 0.8178584409394867 4.2701237450964594E-190 neuronal_cell_body GO:0043025 12133 215 66 1 621 4 2 false 0.8182371790717224 0.8182371790717224 3.1563152846547707E-173 cellular_homeostasis GO:0019725 12133 585 66 3 7566 56 2 false 0.8188456789124904 0.8188456789124904 0.0 cellular_response_to_organic_nitrogen GO:0071417 12133 323 66 3 1478 19 4 false 0.8200401165943788 0.8200401165943788 0.0 ion_gated_channel_activity GO:0022839 12133 204 66 1 469 3 2 false 0.8204977184808485 0.8204977184808485 9.436824095674645E-139 phosphatase_binding GO:0019902 12133 108 66 1 1005 15 1 false 0.8205777636911246 0.8205777636911246 3.014042549641288E-148 nucleoside-triphosphatase_activity GO:0017111 12133 1059 66 10 1080 10 1 false 0.8210338645610362 0.8210338645610362 1.2343281293318376E-44 macromolecule_methylation GO:0043414 12133 149 66 1 5645 64 3 false 0.8212439733477843 0.8212439733477843 2.745935058350772E-298 second-messenger-mediated_signaling GO:0019932 12133 257 66 2 1813 21 1 false 0.8213510441069222 0.8213510441069222 1.643E-320 protein_import GO:0017038 12133 225 66 2 2509 34 2 false 0.8236838411962031 0.8236838411962031 0.0 regulation_of_protein_kinase_B_signaling_cascade GO:0051896 12133 80 66 1 646 13 2 false 0.8237719033800072 0.8237719033800072 1.7925842553941532E-104 nuclear_import GO:0051170 12133 203 66 2 2389 36 3 false 0.8245787808839868 0.8245787808839868 7.452348105569065E-301 DNA_damage_checkpoint GO:0000077 12133 126 66 1 574 7 2 false 0.8253955679674932 0.8253955679674932 1.5833464450994651E-130 positive_regulation_of_mitochondrial_membrane_permeability GO:0035794 12133 38 66 1 46 1 1 false 0.8260869565217287 0.8260869565217287 3.832404138206993E-9 positive_regulation_of_developmental_process GO:0051094 12133 603 66 3 4731 34 3 false 0.8270132594401907 0.8270132594401907 0.0 nitrogen_compound_transport GO:0071705 12133 428 66 4 2783 36 1 false 0.8272800906122072 0.8272800906122072 0.0 cellular_response_to_nitrogen_compound GO:1901699 12133 347 66 3 1721 21 2 false 0.8275984846752333 0.8275984846752333 0.0 regulation_of_cell_development GO:0060284 12133 446 66 3 1519 14 2 false 0.8276279403031542 0.8276279403031542 0.0 endomembrane_system GO:0012505 12133 1211 66 6 9983 66 1 false 0.8277394793716248 0.8277394793716248 0.0 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 66 11 7451 64 1 false 0.8291907072216256 0.8291907072216256 0.0 double-strand_break_repair GO:0006302 12133 109 66 1 368 5 1 false 0.8292960688205664 0.8292960688205664 1.714085470943145E-96 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 66 4 614 4 1 false 0.8293033236301761 0.8293033236301761 4.862693095923331E-49 ion_binding GO:0043167 12133 4448 66 28 8962 63 1 false 0.8296192531219959 0.8296192531219959 0.0 regulation_of_cell_projection_organization GO:0031344 12133 227 66 1 1532 11 2 false 0.8297278664579952 0.8297278664579952 2.603761260472357E-278 neuron_differentiation GO:0030182 12133 812 66 5 2154 17 2 false 0.8306101846510152 0.8306101846510152 0.0 protein_deubiquitination GO:0016579 12133 64 66 1 77 1 1 false 0.8311688311688372 0.8311688311688372 5.4422836360017854E-15 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 66 2 541 6 2 false 0.8322144725722886 0.8322144725722886 1.01164377942614E-160 sarcomere GO:0030017 12133 129 66 1 155 1 2 false 0.8322580645161162 0.8322580645161162 4.189006503961452E-30 JAK-STAT_cascade GO:0007259 12133 96 66 1 806 14 1 false 0.8331922062018681 0.8331922062018681 3.5358394194592134E-127 prostaglandin_biosynthetic_process GO:0001516 12133 20 66 1 24 1 2 false 0.8333333333333302 0.8333333333333302 9.410878976096304E-5 neurotrophin_TRKA_receptor_binding GO:0005168 12133 5 66 1 6 1 1 false 0.8333333333333331 0.8333333333333331 0.1666666666666666 insulin_receptor_signaling_pathway GO:0008286 12133 151 66 2 617 12 2 false 0.8342800445022565 0.8342800445022565 2.0667953594506098E-148 androgen_receptor_signaling_pathway GO:0030521 12133 62 66 2 102 4 1 false 0.83434814069639 0.83434814069639 2.6706454874295595E-29 postsynaptic_membrane GO:0045211 12133 126 66 1 151 1 1 false 0.8344370860926633 0.8344370860926633 4.265026398149926E-29 positive_regulation_of_catabolic_process GO:0009896 12133 137 66 1 3517 45 3 false 0.834614742825174 0.834614742825174 1.0965595914697655E-250 response_to_hormone_stimulus GO:0009725 12133 611 66 5 1784 19 2 false 0.8350281539201417 0.8350281539201417 0.0 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 66 10 1072 10 2 false 0.8356125156098285 0.8356125156098285 3.811291228230986E-41 regulation_of_membrane_potential GO:0042391 12133 216 66 1 478 3 1 false 0.8361818872967476 0.8361818872967476 3.2092050959317294E-142 cytoskeleton_organization GO:0007010 12133 719 66 4 2031 15 1 false 0.8363431883550512 0.8363431883550512 0.0 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 66 28 4544 54 3 false 0.836623706490207 0.836623706490207 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 66 2 165 2 2 false 0.8370288248337823 0.8370288248337823 1.3866478491946915E-20 carbohydrate_catabolic_process GO:0016052 12133 112 66 1 2356 37 2 false 0.8373826494270552 0.8373826494270552 5.972721726257644E-195 skeletal_muscle_fiber_development GO:0048741 12133 81 66 1 179 3 2 false 0.8381835223724869 0.8381835223724869 4.89646079793881E-53 maintenance_of_protein_location GO:0045185 12133 100 66 1 1490 26 2 false 0.8383241408300344 0.8383241408300344 1.3409119998512189E-158 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 66 5 1053 10 1 false 0.8383522568939719 0.8383522568939719 1.6418245301060377E-306 biological_adhesion GO:0022610 12133 714 66 3 10446 66 1 false 0.8383574039352428 0.8383574039352428 0.0 calcium_ion_homeostasis GO:0055074 12133 213 66 2 286 3 2 false 0.8387927861612303 0.8387927861612303 5.1764989660558217E-70 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 66 5 723 9 2 false 0.8390136879668846 0.8390136879668846 2.0953844092707462E-201 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 66 1 198 5 2 false 0.8391750964137227 0.8391750964137227 2.9049351003528108E-52 protein_kinase_B_signaling_cascade GO:0043491 12133 98 66 1 806 14 1 false 0.8397102325909365 0.8397102325909365 6.677067387386742E-129 GTPase_activator_activity GO:0005096 12133 192 66 1 732 6 4 false 0.8400025645780111 0.8400025645780111 3.4613287013713416E-182 nucleoside-triphosphatase_regulator_activity GO:0060589 12133 361 66 2 1452 12 2 false 0.840169669467794 0.840169669467794 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 66 3 214 3 1 false 0.8403267426814965 0.8403267426814965 7.108512362452622E-20 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 66 13 2560 26 2 false 0.8408345701804298 0.8408345701804298 0.0 hydrolase_activity,_acting_on_ester_bonds GO:0016788 12133 814 66 4 2556 17 1 false 0.8413550848927718 0.8413550848927718 0.0 cellular_calcium_ion_homeostasis GO:0006874 12133 205 66 2 274 3 3 false 0.8427247934545259 0.8427247934545259 1.2663672117972438E-66 nucleic_acid_transport GO:0050657 12133 124 66 2 135 2 1 false 0.8431177446102683 0.8431177446102683 2.2345648964967124E-16 response_to_lipid GO:0033993 12133 515 66 4 1783 19 1 false 0.8445963350191599 0.8445963350191599 0.0 response_to_monosaccharide_stimulus GO:0034284 12133 98 66 1 116 1 1 false 0.8448275862069218 0.8448275862069218 1.7787368796427923E-21 establishment_of_vesicle_localization GO:0051650 12133 101 66 1 1637 29 3 false 0.84484531373814 0.84484531373814 5.290047035844154E-164 small_GTPase_binding GO:0031267 12133 126 66 2 137 2 1 false 0.8453198797766951 0.8453198797766951 1.8889221296599312E-16 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 66 2 381 5 2 false 0.8466838976109125 0.8466838976109125 8.855041133991382E-114 protein_stabilization GO:0050821 12133 60 66 1 99 2 1 false 0.8472479901050973 0.8472479901050973 1.818679918792965E-28 mitochondrial_transport GO:0006839 12133 124 66 1 2454 36 2 false 0.8474767411523543 0.8474767411523543 1.607876790046367E-212 steroid_metabolic_process GO:0008202 12133 182 66 1 5438 55 2 false 0.8476811492874733 0.8476811492874733 0.0 Fc-gamma_receptor_signaling_pathway GO:0038094 12133 72 66 3 76 3 1 false 0.8483641536272892 0.8483641536272892 7.79438414622254E-7 gamete_generation GO:0007276 12133 355 66 1 581 2 3 false 0.84910083684499 0.84910083684499 6.960007714092178E-168 transmembrane_signaling_receptor_activity GO:0004888 12133 539 66 1 633 1 1 false 0.8515007898894003 0.8515007898894003 7.293829448224349E-115 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 66 4 78 4 1 false 0.8520952731478723 0.8520952731478723 1.3144749986854762E-5 androgen_receptor_binding GO:0050681 12133 38 66 1 62 2 1 false 0.8540454785827765 0.8540454785827765 1.0311688046013243E-17 nervous_system_development GO:0007399 12133 1371 66 7 2686 17 1 false 0.8553698095460337 0.8553698095460337 0.0 morphogenesis_of_a_branching_epithelium GO:0061138 12133 160 66 1 336 3 2 false 0.8574492805434125 0.8574492805434125 2.40154258695507E-100 regulation_of_inflammatory_response GO:0050727 12133 151 66 1 702 8 3 false 0.8575278521747999 0.8575278521747999 5.1007818439049374E-158 organelle_inner_membrane GO:0019866 12133 264 66 1 9083 66 3 false 0.8582716894320535 0.8582716894320535 0.0 monovalent_inorganic_cation_transmembrane_transporter_activity GO:0015077 12133 198 66 1 413 3 2 false 0.8598662489706768 0.8598662489706768 1.708187099767858E-123 purine_ribonucleotide_binding GO:0032555 12133 1641 66 13 1660 13 2 false 0.8605357858882419 0.8605357858882419 8.870449707822982E-45 nuclear_division GO:0000280 12133 326 66 2 351 2 1 false 0.8624338624341342 0.8624338624341342 8.671827254018066E-39 transporter_activity GO:0005215 12133 746 66 3 10383 66 2 false 0.8625550902916028 0.8625550902916028 0.0 enzyme_activator_activity GO:0008047 12133 321 66 2 1413 14 2 false 0.8626236659135149 0.8626236659135149 0.0 mitochondrial_inner_membrane GO:0005743 12133 241 66 1 382 2 2 false 0.8643690481097188 0.8643690481097188 1.3545216387089424E-108 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 66 9 378 9 1 false 0.8645356088461195 0.8645356088461195 2.5686196448553377E-13 regulation_of_cell_growth GO:0001558 12133 243 66 1 1344 10 3 false 0.8649003372483078 0.8649003372483078 4.9010314548000585E-275 organic_acid_transport GO:0015849 12133 138 66 1 2569 36 2 false 0.8649025802304633 0.8649025802304633 8.315109453797594E-233 regulation_of_neuron_differentiation GO:0045664 12133 281 66 1 853 5 2 false 0.8651897876335326 0.8651897876335326 5.679328733626827E-234 cell_cycle_checkpoint GO:0000075 12133 202 66 2 217 2 1 false 0.8662314388120638 0.8662314388120638 1.925703524045096E-23 NAD-dependent_histone_deacetylase_activity_(H3-K9_specific) GO:0046969 12133 13 66 1 15 1 2 false 0.8666666666666659 0.8666666666666659 0.009523809523809518 vesicle-mediated_transport GO:0016192 12133 895 66 9 2783 36 1 false 0.8667817084523466 0.8667817084523466 0.0 cellular_component_morphogenesis GO:0032989 12133 810 66 5 5068 45 4 false 0.8675426338260643 0.8675426338260643 0.0 small_molecule_biosynthetic_process GO:0044283 12133 305 66 1 2426 15 2 false 0.8675556291654138 0.8675556291654138 0.0 lytic_vacuole GO:0000323 12133 258 66 3 310 4 1 false 0.8676898563230685 0.8676898563230685 2.1177419387644615E-60 protein_localization_to_membrane GO:0072657 12133 94 66 1 1452 30 2 false 0.8685198125228423 0.8685198125228423 1.4056786116419224E-150 carboxylic_acid_biosynthetic_process GO:0046394 12133 206 66 1 4363 42 3 false 0.8701304871820026 0.8701304871820026 0.0 translation_elongation_factor_activity GO:0003746 12133 22 66 1 180 15 2 false 0.8701844392565588 0.8701844392565588 1.0368938565383413E-28 organic_acid_biosynthetic_process GO:0016053 12133 206 66 1 4345 42 3 false 0.8712563712208505 0.8712563712208505 0.0 activation_of_phospholipase_C_activity GO:0007202 12133 85 66 2 91 2 1 false 0.8717948717948597 0.8717948717948597 1.5002312651502098E-9 phospholipid_metabolic_process GO:0006644 12133 222 66 1 3035 27 3 false 0.8725587550708492 0.8725587550708492 0.0 apical_junction_assembly GO:0043297 12133 37 66 1 58 2 1 false 0.8729582577132535 0.8729582577132535 2.991639077401756E-16 muscle_contraction GO:0006936 12133 220 66 1 252 1 1 false 0.8730158730158051 0.8730158730158051 2.9388717314840356E-41 DNA_integrity_checkpoint GO:0031570 12133 130 66 1 202 2 1 false 0.8740948721737103 0.8740948721737103 1.23666756413938E-56 establishment_of_organelle_localization GO:0051656 12133 159 66 1 2851 36 2 false 0.8749496234106051 0.8749496234106051 1.187631057130769E-265 anatomical_structure_morphogenesis GO:0009653 12133 1664 66 8 3447 21 2 false 0.8764525419617953 0.8764525419617953 0.0 nucleoside_binding GO:0001882 12133 1639 66 13 4455 44 3 false 0.8778749694848477 0.8778749694848477 0.0 regulation_of_ERK1_and_ERK2_cascade GO:0070372 12133 101 66 1 439 8 2 false 0.878875979858779 0.878875979858779 3.260158634829054E-102 regulation_of_leukocyte_activation GO:0002694 12133 278 66 2 948 11 3 false 0.8791775119562546 0.8791775119562546 2.7935655578419027E-248 lipid_biosynthetic_process GO:0008610 12133 360 66 2 4386 43 2 false 0.8793619521730281 0.8793619521730281 0.0 oxidation-reduction_process GO:0055114 12133 740 66 3 2877 18 1 false 0.8795876860174137 0.8795876860174137 0.0 inositol_lipid-mediated_signaling GO:0048017 12133 173 66 1 1813 21 1 false 0.8797685918245592 0.8797685918245592 3.525454591975737E-247 cellular_glucan_metabolic_process GO:0006073 12133 59 66 1 67 1 2 false 0.8805970149253893 0.8805970149253893 1.5331870071919512E-10 regulation_of_cell_morphogenesis GO:0022604 12133 267 66 1 1647 12 3 false 0.8811931795515042 0.8811931795515042 3.9027101E-316 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 66 1 1586 11 3 false 0.8818412948864275 0.8818412948864275 1.5665E-319 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 66 23 3120 31 4 false 0.8822470862762137 0.8822470862762137 0.0 regulation_of_cardiac_muscle_contraction_by_regulation_of_the_release_of_sequestered_calcium_ion GO:0010881 12133 15 66 1 17 1 2 false 0.8823529411764717 0.8823529411764717 0.0073529411764705925 response_to_alcohol GO:0097305 12133 194 66 1 1822 19 2 false 0.883554614433284 0.883554614433284 1.608783098574704E-267 protein_polymerization GO:0051258 12133 145 66 1 284 3 1 false 0.8840527186880325 0.8840527186880325 7.244587792673789E-85 GTPase_regulator_activity GO:0030695 12133 351 66 2 621 5 2 false 0.8844204936419252 0.8844204936419252 7.115229923126785E-184 calcium_ion_transport_into_cytosol GO:0060402 12133 71 66 1 733 21 3 false 0.88591677237169 0.88591677237169 1.0696199620793456E-100 branching_morphogenesis_of_an_epithelial_tube GO:0048754 12133 137 66 1 267 3 2 false 0.8859476441792691 0.8859476441792691 9.47152683261942E-80 regulation_of_cell_cycle_process GO:0010564 12133 382 66 3 1096 13 2 false 0.8861620990800764 0.8861620990800764 7.137372224746455E-307 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 66 1 71 1 3 false 0.8873239436619828 0.8873239436619828 9.399268641403064E-11 proteasomal_protein_catabolic_process GO:0010498 12133 231 66 4 498 12 2 false 0.8882090498213706 0.8882090498213706 1.2543475178088858E-148 glucose_metabolic_process GO:0006006 12133 183 66 1 206 1 1 false 0.888349514563178 0.888349514563178 5.590923529140016E-31 response_to_oxidative_stress GO:0006979 12133 221 66 1 2540 24 1 false 0.8886520562734914 0.8886520562734914 0.0 system_process GO:0003008 12133 1272 66 6 4095 27 1 false 0.8888177958629786 0.8888177958629786 0.0 mitochondrial_part GO:0044429 12133 557 66 3 7185 65 3 false 0.8895413885258936 0.8895413885258936 0.0 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 66 2 929 11 2 false 0.8916894087612844 0.8916894087612844 1.7613668775256747E-246 regulation_of_mRNA_stability GO:0043488 12133 33 66 1 37 1 1 false 0.8918918918918968 0.8918918918918968 1.5141191611779804E-5 receptor_activity GO:0004872 12133 790 66 3 10257 66 1 false 0.8926265543391814 0.8926265543391814 0.0 histone_modification GO:0016570 12133 306 66 2 2375 28 2 false 0.893324727370002 0.893324727370002 0.0 ribonucleoside_metabolic_process GO:0009119 12133 1071 66 10 1083 10 1 false 0.8941425346946495 0.8941425346946495 1.9559437642804265E-28 GTP_catabolic_process GO:0006184 12133 614 66 5 957 10 4 false 0.8959633348655203 0.8959633348655203 2.3934835856107606E-270 leukocyte_chemotaxis GO:0030595 12133 107 66 1 249 4 2 false 0.8961593962147985 0.8961593962147985 2.556499812614757E-73 negative_regulation_of_MAPK_cascade GO:0043409 12133 99 66 1 537 11 3 false 0.896176444592475 0.896176444592475 7.769471694565091E-111 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 66 12 7461 64 2 false 0.8973696348845595 0.8973696348845595 0.0 enzyme_inhibitor_activity GO:0004857 12133 240 66 1 1075 9 2 false 0.898071304027626 0.898071304027626 4.258934911432728E-247 large_ribosomal_subunit GO:0015934 12133 73 66 6 132 14 1 false 0.8985526928703857 0.8985526928703857 5.5437540818743186E-39 lipid_transport GO:0006869 12133 158 66 1 2581 36 3 false 0.89875443639957 0.89875443639957 2.1688704965711523E-257 regulation_of_biosynthetic_process GO:0009889 12133 3012 66 25 5483 53 2 false 0.8994790517261426 0.8994790517261426 0.0 Peyer's_patch_development GO:0048541 12133 9 66 1 10 1 1 false 0.8999999999999996 0.8999999999999996 0.0999999999999999 lipid_metabolic_process GO:0006629 12133 769 66 4 7599 64 3 false 0.9000313671276347 0.9000313671276347 0.0 response_to_molecule_of_bacterial_origin GO:0002237 12133 194 66 1 1960 22 3 false 0.9003458764770877 0.9003458764770877 5.221043387884517E-274 modification-dependent_protein_catabolic_process GO:0019941 12133 378 66 9 400 10 2 false 0.9005673986025415 0.9005673986025415 1.150456419433401E-36 single_organism_reproductive_process GO:0044702 12133 539 66 2 8107 57 2 false 0.9005783501579786 0.9005783501579786 0.0 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 66 5 956 10 2 false 0.900691374372554 0.900691374372554 3.936677708897206E-269 striated_muscle_tissue_development GO:0014706 12133 285 66 3 295 3 1 false 0.9013898612028302 0.9013898612028302 8.482306621073292E-19 ubiquitin-specific_protease_activity GO:0004843 12133 46 66 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 'de_novo'_posttranslational_protein_folding GO:0051084 12133 46 66 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 neuron_projection GO:0043005 12133 534 66 2 1043 6 2 false 0.9021136629947989 0.9021136629947989 5.7946905775E-313 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 66 10 1014 10 1 false 0.9052413804303717 0.9052413804303717 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 66 10 1014 10 1 false 0.9052413804303717 0.9052413804303717 3.301546202575714E-24 maintenance_of_protein_location_in_cell GO:0032507 12133 90 66 1 933 23 3 false 0.9058183353311909 0.9058183353311909 6.448935914517526E-128 Ras_GTPase_binding GO:0017016 12133 120 66 2 126 2 1 false 0.9066666666666439 0.9066666666666439 2.030392220357244E-10 protein_homodimerization_activity GO:0042803 12133 471 66 3 1035 10 2 false 0.9070323827335383 0.9070323827335383 7.159384282986134E-309 guanyl_nucleotide_binding GO:0019001 12133 450 66 2 1650 13 1 false 0.907327175584782 0.907327175584782 0.0 cation_transport GO:0006812 12133 606 66 4 833 7 1 false 0.9076832520661173 0.9076832520661173 4.047492354513465E-211 ryanodine-sensitive_calcium-release_channel_activity GO:0005219 12133 20 66 1 22 1 1 false 0.9090909090909052 0.9090909090909052 0.004329004329004315 guanyl_ribonucleotide_binding GO:0032561 12133 450 66 2 1641 13 2 false 0.9092233625976541 0.9092233625976541 0.0 cell_adhesion GO:0007155 12133 712 66 3 7542 56 2 false 0.9094639698551055 0.9094639698551055 0.0 protein_localization_to_mitochondrion GO:0070585 12133 67 66 1 516 17 1 false 0.9097056347120289 0.9097056347120289 5.765661430685337E-86 cell_migration GO:0016477 12133 734 66 7 785 8 1 false 0.9098906370439873 0.9098906370439873 1.8763224028220524E-81 anion_transport GO:0006820 12133 242 66 1 833 7 1 false 0.9104458170411317 0.9104458170411317 3.24242391461898E-217 heart_development GO:0007507 12133 343 66 1 2876 19 3 false 0.9111684737305228 0.9111684737305228 0.0 heme_binding GO:0020037 12133 72 66 1 79 1 1 false 0.9113924050632815 0.9113924050632815 3.4497584076401995E-10 positive_regulation_of_GTPase_activity GO:0043547 12133 241 66 1 923 8 3 false 0.9121026213576275 0.9121026213576275 2.240962289646545E-229 ERK1_and_ERK2_cascade GO:0070371 12133 118 66 1 502 9 1 false 0.9123098950879073 0.9123098950879073 3.0844274691588307E-118 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 66 2 86 3 2 false 0.9124487004104362 0.9124487004104362 1.0344828145516245E-17 regulation_of_cytoskeleton_organization GO:0051493 12133 250 66 1 955 8 2 false 0.9127143998519853 0.9127143998519853 1.2229840665192896E-237 regulation_of_cellular_catabolic_process GO:0031329 12133 494 66 3 5000 54 3 false 0.9135271054027633 0.9135271054027633 0.0 lipid_catabolic_process GO:0016042 12133 155 66 1 2566 39 2 false 0.9135957990016638 0.9135957990016638 2.0289846670236068E-253 defense_response_to_virus GO:0051607 12133 160 66 1 1130 16 3 false 0.9146095867782933 0.9146095867782933 2.076664675339186E-199 cellular_lipid_metabolic_process GO:0044255 12133 606 66 3 7304 65 2 false 0.9151476002252359 0.9151476002252359 0.0 chromosomal_part GO:0044427 12133 512 66 3 5337 56 2 false 0.9155152192982885 0.9155152192982885 0.0 adherens_junction_organization GO:0034332 12133 85 66 1 152 3 1 false 0.9165127222027765 0.9165127222027765 7.834980933972919E-45 lipid_binding GO:0008289 12133 571 66 2 8962 63 1 false 0.9171843705136764 0.9171843705136764 0.0 perinuclear_region_of_cytoplasm GO:0048471 12133 416 66 2 5117 49 1 false 0.9172962911566411 0.9172962911566411 0.0 protein_processing GO:0016485 12133 113 66 1 123 1 1 false 0.918699186991829 0.918699186991829 6.665856545071852E-15 cellular_response_to_organic_cyclic_compound GO:0071407 12133 190 66 1 1540 19 2 false 0.9193504159387147 0.9193504159387147 4.3845861432353096E-249 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 66 9 3972 46 4 false 0.9194729399664359 0.9194729399664359 0.0 leukocyte_differentiation GO:0002521 12133 299 66 1 2177 17 2 false 0.919668028935839 0.919668028935839 0.0 nucleoplasm_part GO:0044451 12133 805 66 7 2767 35 2 false 0.9206567941370913 0.9206567941370913 0.0 DNA_conformation_change GO:0071103 12133 194 66 1 791 9 1 false 0.9217104794177766 0.9217104794177766 1.3022788504353465E-190 positive_regulation_of_gene_expression GO:0010628 12133 1008 66 9 4103 52 3 false 0.9218202585378664 0.9218202585378664 0.0 cell_proliferation GO:0008283 12133 1316 66 6 8052 57 1 false 0.9220362107793366 0.9220362107793366 0.0 positive_regulation_of_cysteine-type_endopeptidase_activity GO:2001056 12133 106 66 1 224 4 3 false 0.924850591066629 0.924850591066629 9.593761035739944E-67 calcium_ion_transport GO:0006816 12133 228 66 2 237 2 1 false 0.925337910319709 0.925337910319709 1.7939063205832563E-16 response_to_organic_cyclic_compound GO:0014070 12133 487 66 3 1783 19 1 false 0.9258071417660987 0.9258071417660987 0.0 meiosis GO:0007126 12133 122 66 1 1243 25 2 false 0.9264141879881709 0.9264141879881709 1.368721434688107E-172 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 66 1 1265 11 3 false 0.9287598334093995 0.9287598334093995 1.9379490968147627E-283 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 66 2 768 5 1 false 0.9288331695931362 0.9288331695931362 1.6461815804374103E-220 integral_to_membrane GO:0016021 12133 2318 66 3 2375 3 1 false 0.9296852778278986 0.9296852778278986 3.0839384482043954E-116 actin_cytoskeleton_organization GO:0030036 12133 373 66 1 768 4 2 false 0.9305415406448556 0.9305415406448556 3.0657297438498186E-230 myofibril GO:0030016 12133 148 66 1 159 1 1 false 0.930817610062944 0.930817610062944 3.462863266418168E-17 protein_modification_process GO:0036211 12133 2370 66 28 3518 48 2 false 0.9308322247463154 0.9308322247463154 0.0 regulation_of_peptidyl-tyrosine_phosphorylation GO:0050730 12133 150 66 1 812 13 2 false 0.9312356463591618 0.9312356463591618 5.072476466269739E-168 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 66 9 3847 51 4 false 0.9313315209699099 0.9313315209699099 0.0 envelope GO:0031975 12133 641 66 2 9983 66 1 false 0.9313773628245985 0.9313773628245985 0.0 mitochondrial_matrix GO:0005759 12133 236 66 1 3218 35 2 false 0.9314743283427573 0.9314743283427573 0.0 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 66 5 149 5 1 false 0.9337928532559904 0.9337928532559904 9.06947215672054E-5 mitosis GO:0007067 12133 326 66 2 953 11 2 false 0.9339243286731616 0.9339243286731616 4.8424843971573165E-265 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 66 1 1206 11 3 false 0.9355755751339295 0.9355755751339295 5.7559641067065754E-275 ribonucleotide_biosynthetic_process GO:0009260 12133 275 66 1 1250 11 3 false 0.9357879944310163 0.9357879944310163 3.3374763917028038E-285 single-organism_metabolic_process GO:0044710 12133 2877 66 18 8027 65 1 false 0.9363233757926286 0.9363233757926286 0.0 monovalent_inorganic_cation_transport GO:0015672 12133 302 66 1 606 4 1 false 0.9372942450289704 0.9372942450289704 1.1660817479890875E-181 inflammatory_response GO:0006954 12133 381 66 2 1437 15 2 false 0.9378483819210859 0.9378483819210859 0.0 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 66 1 971 31 2 false 0.9379782554254805 0.9379782554254805 1.7939571902377886E-121 purine_nucleoside_binding GO:0001883 12133 1631 66 13 1639 13 1 false 0.938151983751504 0.938151983751504 7.876250956196666E-22 stress-activated_MAPK_cascade GO:0051403 12133 207 66 2 504 9 2 false 0.9393370801652658 0.9393370801652658 1.7060805667457382E-147 ion_transmembrane_transporter_activity GO:0015075 12133 469 66 3 589 5 2 false 0.939968704232907 0.939968704232907 1.1842155919657181E-128 single-organism_biosynthetic_process GO:0044711 12133 313 66 1 5633 49 2 false 0.940013150599931 0.940013150599931 0.0 nuclear_transport GO:0051169 12133 331 66 5 1148 28 1 false 0.9405689927996684 0.9405689927996684 1.3196682196913852E-298 nucleocytoplasmic_transport GO:0006913 12133 327 66 5 331 5 1 false 0.9406689703262207 0.9406689703262207 2.036102168267257E-9 positive_regulation_of_intracellular_transport GO:0032388 12133 126 66 1 1370 29 3 false 0.9408893684750403 0.9408893684750403 5.304932497681123E-182 response_to_glucocorticoid_stimulus GO:0051384 12133 96 66 1 102 1 1 false 0.9411764705882397 0.9411764705882397 7.426393311971062E-10 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 66 10 1007 10 2 false 0.9417356302955944 0.9417356302955944 7.008686204750717E-16 response_to_drug GO:0042493 12133 286 66 1 2369 22 1 false 0.941805721098681 0.941805721098681 0.0 multicellular_organism_reproduction GO:0032504 12133 482 66 2 4643 42 2 false 0.9420274466027925 0.9420274466027925 0.0 regulation_of_nervous_system_development GO:0051960 12133 381 66 1 1805 12 2 false 0.9424395703991695 0.9424395703991695 0.0 regulation_of_immune_effector_process GO:0002697 12133 188 66 1 891 12 2 false 0.9429515917715967 0.9429515917715967 1.2449327492079068E-198 organophosphate_catabolic_process GO:0046434 12133 1000 66 11 2495 38 2 false 0.9452608082247647 0.9452608082247647 0.0 receptor-mediated_endocytosis GO:0006898 12133 157 66 1 411 6 1 false 0.9455449371868854 0.9455449371868854 4.873503831957431E-118 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 66 54 7976 63 2 false 0.9469166555695427 0.9469166555695427 0.0 embryonic_morphogenesis GO:0048598 12133 406 66 1 2812 19 3 false 0.9488497217576495 0.9488497217576495 0.0 structural_constituent_of_cytoskeleton GO:0005200 12133 88 66 1 526 16 1 false 0.9490121673700173 0.9490121673700173 1.4915391741340796E-102 positive_regulation_of_intracellular_protein_transport GO:0090316 12133 92 66 1 737 22 4 false 0.9491607836930663 0.9491607836930663 7.301092489476398E-120 hexose_metabolic_process GO:0019318 12133 206 66 1 217 1 1 false 0.9493087557602818 0.9493087557602818 1.0279992997812003E-18 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 66 5 199 5 1 false 0.9502563321658456 0.9502563321658456 5.075884472869322E-5 striated_muscle_cell_development GO:0055002 12133 133 66 1 211 3 2 false 0.9507109004739123 0.9507109004739123 7.542852200614712E-60 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 66 1 4251 44 6 false 0.9508952770218788 0.9508952770218788 0.0 regulation_of_transport GO:0051049 12133 942 66 8 3017 39 2 false 0.9528845772960606 0.9528845772960606 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 66 13 1635 13 2 false 0.9531616302771647 0.9531616302771647 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 66 13 1639 13 1 false 0.9532738442456664 0.9532738442456664 3.7483303336303164E-17 membrane-bounded_organelle GO:0043227 12133 7284 66 54 7980 63 1 false 0.955279860740975 0.955279860740975 0.0 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 66 1 3799 48 1 false 0.9560827406761483 0.9560827406761483 0.0 organic_anion_transport GO:0015711 12133 184 66 1 1631 26 2 false 0.9566238529054776 0.9566238529054776 8.274450263154378E-249 regulation_of_growth GO:0040008 12133 447 66 1 6651 45 2 false 0.9567845980377233 0.9567845980377233 0.0 viral_reproduction GO:0016032 12133 633 66 27 634 27 1 false 0.9574132492113763 0.9574132492113763 0.0015772870662463625 syntaxin_binding GO:0019905 12133 33 66 1 42 2 1 false 0.9581881533101175 0.9581881533101175 2.2426964962644543E-9 lipid_localization GO:0010876 12133 181 66 1 1642 27 1 false 0.9584236568203061 0.9584236568203061 1.1319861049738569E-246 positive_regulation_of_protein_transport GO:0051222 12133 154 66 1 1301 25 3 false 0.9584544637945193 0.9584544637945193 9.736449433094532E-205 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 66 1 73 1 1 false 0.9589041095890459 0.9589041095890459 1.607820438613435E-5 response_to_hexose_stimulus GO:0009746 12133 94 66 1 98 1 1 false 0.9591836734693473 0.9591836734693473 2.7683346805893783E-7 regulation_of_response_to_external_stimulus GO:0032101 12133 314 66 1 2524 24 2 false 0.9594045386212209 0.9594045386212209 0.0 nuclear_chromosome_part GO:0044454 12133 244 66 1 2878 36 3 false 0.9596339545599057 0.9596339545599057 0.0 regulation_of_neurogenesis GO:0050767 12133 344 66 1 1039 8 4 false 0.9604518582473485 0.9604518582473485 1.1807712079388562E-285 activation_of_adenylate_cyclase_activity GO:0007190 12133 50 66 1 52 1 1 false 0.9615384615384723 0.9615384615384723 7.54147812971345E-4 regulation_of_system_process GO:0044057 12133 373 66 1 2254 18 2 false 0.9619855540784606 0.9619855540784606 0.0 cell-type_specific_apoptotic_process GO:0097285 12133 270 66 1 1373 15 1 false 0.9632396371367888 0.9632396371367888 9.434604867208542E-295 actin_filament-based_process GO:0030029 12133 431 66 1 7541 56 1 false 0.963417505213026 0.963417505213026 0.0 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 66 10 1085 10 1 false 0.9635905122021459 0.9635905122021459 1.7413918354446858E-11 mononuclear_cell_proliferation GO:0032943 12133 161 66 1 167 1 1 false 0.9640718562873847 0.9640718562873847 3.634774947475864E-11 cell_projection_part GO:0044463 12133 491 66 1 9983 66 2 false 0.9645569799551907 0.9645569799551907 0.0 epithelial_cell_differentiation GO:0030855 12133 397 66 1 2228 17 2 false 0.9648953926930037 0.9648953926930037 0.0 gated_channel_activity GO:0022836 12133 204 66 1 304 3 1 false 0.9651230807986271 0.9651230807986271 4.829178211839583E-83 nucleotide_biosynthetic_process GO:0009165 12133 322 66 1 1318 12 2 false 0.9658769071048519 0.9658769071048519 2.1862113E-317 response_to_bacterium GO:0009617 12133 273 66 1 475 4 1 false 0.967851892768208 0.967851892768208 5.69705453618735E-140 organelle_envelope GO:0031967 12133 629 66 2 7756 63 3 false 0.9686405269760257 0.9686405269760257 0.0 Golgi_apparatus GO:0005794 12133 828 66 3 8213 66 2 false 0.9686670271646257 0.9686670271646257 0.0 oxidoreductase_activity GO:0016491 12133 491 66 1 4974 34 2 false 0.971162990617864 0.971162990617864 0.0 canonical_Wnt_receptor_signaling_pathway GO:0060070 12133 152 66 1 260 4 1 false 0.9711944112451039 0.9711944112451039 4.5351475920205146E-76 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 66 25 4972 52 3 false 0.9716112661603976 0.9716112661603976 0.0 virus-host_interaction GO:0019048 12133 355 66 12 588 27 2 false 0.9722398879452177 0.9722398879452177 1.0104535019427035E-170 endoplasmic_reticulum GO:0005783 12133 854 66 3 8213 66 2 false 0.973665058690208 0.973665058690208 0.0 ncRNA_processing GO:0034470 12133 186 66 3 649 22 2 false 0.9739435156438565 0.9739435156438565 4.048832162241149E-168 nuclear_chromosome GO:0000228 12133 278 66 1 2899 36 3 false 0.9740713661972669 0.9740713661972669 0.0 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 66 1 4156 45 3 false 0.97429223026846 0.97429223026846 0.0 positive_regulation_of_cell_proliferation GO:0008284 12133 558 66 2 3155 29 3 false 0.9748882740491414 0.9748882740491414 0.0 chordate_embryonic_development GO:0043009 12133 471 66 2 477 2 1 false 0.974974895618767 0.974974895618767 6.308586670641318E-14 leukocyte_activation GO:0045321 12133 475 66 2 1729 18 2 false 0.976414200749042 0.976414200749042 0.0 organelle_localization GO:0051640 12133 216 66 1 1845 30 1 false 0.9768789313901132 0.9768789313901132 1.7282331973036908E-288 epithelium_migration GO:0090132 12133 130 66 3 131 3 1 false 0.9770992366412085 0.9770992366412085 0.007633587786259341 transcription,_DNA-dependent GO:0006351 12133 2643 66 25 4063 48 3 false 0.9779588082397792 0.9779588082397792 0.0 peptide_binding GO:0042277 12133 178 66 1 182 1 1 false 0.9780219780219295 0.9780219780219295 2.2611831618281403E-8 response_to_glucose_stimulus GO:0009749 12133 92 66 1 94 1 1 false 0.9787234042553515 0.9787234042553515 2.2878059940517224E-4 actin_binding GO:0003779 12133 299 66 1 556 5 1 false 0.9793402168664329 0.9793402168664329 6.115970052445393E-166 regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030802 12133 143 66 1 167 2 3 false 0.9800880167376728 0.9800880167376728 1.5904574919997758E-29 chromosome GO:0005694 12133 592 66 3 3226 38 1 false 0.9802048573629722 0.9802048573629722 0.0 phosphatase_activity GO:0016791 12133 306 66 2 465 6 2 false 0.9806085368387261 0.9806085368387261 4.9712656169712896E-129 hemopoiesis GO:0030097 12133 462 66 3 491 4 1 false 0.9812108096744478 0.9812108096744478 1.8682876304369947E-47 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 66 10 2517 38 2 false 0.9815959519305415 0.9815959519305415 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 66 12 1319 12 1 false 0.9818803273272403 0.9818803273272403 1.1504554077729292E-6 macromolecular_complex_assembly GO:0065003 12133 973 66 11 1603 26 2 false 0.9826899658149181 0.9826899658149181 0.0 protein_deacetylation GO:0006476 12133 57 66 1 58 1 1 false 0.982758620689673 0.982758620689673 0.017241379310345032 protein_homooligomerization GO:0051260 12133 183 66 1 288 4 1 false 0.9829715641651562 0.9829715641651562 1.8197847122731807E-81 interphase GO:0051325 12133 233 66 2 253 3 1 false 0.982974182696793 0.982974182696793 4.555981744751407E-30 cytoskeleton GO:0005856 12133 1430 66 11 3226 38 1 false 0.9830841381383104 0.9830841381383104 0.0 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 66 3 381 10 2 false 0.9832843668432919 0.9832843668432919 4.820433761728018E-112 ion_transport GO:0006811 12133 833 66 7 2323 34 1 false 0.9834308577187856 0.9834308577187856 0.0 membrane GO:0016020 12133 4398 66 19 10701 66 1 false 0.986251480071838 0.986251480071838 0.0 oxoacid_metabolic_process GO:0043436 12133 667 66 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 peptidyl-amino_acid_modification GO:0018193 12133 623 66 3 2370 28 1 false 0.9888063063365976 0.9888063063365976 0.0 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 66 10 2643 38 2 false 0.9891878900911623 0.9891878900911623 0.0 transition_metal_ion_binding GO:0046914 12133 1457 66 5 2699 17 1 false 0.9893874253848979 0.9893874253848979 0.0 glycosyl_compound_catabolic_process GO:1901658 12133 956 66 10 2175 37 2 false 0.9895780464901214 0.9895780464901214 0.0 carbohydrate_metabolic_process GO:0005975 12133 515 66 1 7453 64 2 false 0.9899762220188344 0.9899762220188344 0.0 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 66 9 672 25 1 false 0.9900534062714663 0.9900534062714663 6.935915883902889E-199 pyrophosphatase_activity GO:0016462 12133 1080 66 10 1081 10 1 false 0.9907493061976227 0.9907493061976227 9.250693802031629E-4 extracellular_region_part GO:0044421 12133 740 66 1 10701 66 2 false 0.991300559493747 0.991300559493747 0.0 regulation_of_gene_expression GO:0010468 12133 2935 66 29 4361 55 2 false 0.9918910089875068 0.9918910089875068 0.0 apoptotic_process GO:0006915 12133 1373 66 15 1385 16 1 false 0.9922766975344782 0.9922766975344782 1.0085392941984968E-29 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 66 9 2849 38 1 false 0.9924530106592965 0.9924530106592965 0.0 organophosphate_biosynthetic_process GO:0090407 12133 477 66 1 4948 48 2 false 0.9924809239464804 0.9924809239464804 0.0 response_to_nutrient_levels GO:0031667 12133 238 66 1 260 2 1 false 0.9931392931394337 0.9931392931394337 2.081158575166241E-32 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 66 1 4947 46 2 false 0.9944040228395065 0.9944040228395065 0.0 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 66 1 5099 46 2 false 0.9947769808580046 0.9947769808580046 0.0 protein_import_into_nucleus GO:0006606 12133 200 66 2 690 22 5 false 0.9951579609591121 0.9951579609591121 1.1794689955817937E-179 extracellular_region GO:0005576 12133 1152 66 2 10701 66 1 false 0.9952167743679206 0.9952167743679206 0.0 purine-containing_compound_catabolic_process GO:0072523 12133 959 66 10 1651 28 6 false 0.9953158238253329 0.9953158238253329 0.0 G-protein_coupled_receptor_signaling_pathway GO:0007186 12133 443 66 1 1975 21 1 false 0.9953219465995028 0.9953219465995028 0.0 elevation_of_cytosolic_calcium_ion_concentration GO:0007204 12133 139 66 1 149 2 1 false 0.9959187375294727 0.9959187375294727 9.160998963939192E-16 carboxylic_acid_metabolic_process GO:0019752 12133 614 66 1 7453 64 2 false 0.9960214475003685 0.9960214475003685 0.0 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 66 24 4395 51 3 false 0.9965662747668451 0.9965662747668451 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 66 24 3611 41 3 false 0.9968153053147925 0.9968153053147925 0.0 establishment_of_protein_localization_to_mitochondrion GO:0072655 12133 66 66 1 211 15 2 false 0.9971686086385187 0.9971686086385187 1.9619733177914497E-56 chemical_homeostasis GO:0048878 12133 677 66 3 990 10 1 false 0.9977835393100573 0.9977835393100573 1.9931274413677286E-267 organic_acid_metabolic_process GO:0006082 12133 676 66 1 7326 65 2 false 0.9982034256265135 0.9982034256265135 0.0 nucleoside_catabolic_process GO:0009164 12133 952 66 10 1516 27 5 false 0.998343562834426 0.998343562834426 0.0 intrinsic_to_membrane GO:0031224 12133 2375 66 3 2995 8 1 false 0.9985313160386023 0.9985313160386023 0.0 membrane-bounded_vesicle GO:0031988 12133 762 66 4 834 7 1 false 0.9985313163701647 0.9985313163701647 6.820230733401612E-106 protein_complex_assembly GO:0006461 12133 743 66 8 1214 24 3 false 0.9986561727932151 0.9986561727932151 0.0 signaling_receptor_activity GO:0038023 12133 633 66 1 1211 9 2 false 0.9987560268716393 0.9987560268716393 0.0 secretion GO:0046903 12133 661 66 3 2323 34 1 false 0.9988963361710416 0.9988963361710416 0.0 response_to_other_organism GO:0051707 12133 475 66 4 1194 27 2 false 0.9989670285408148 0.9989670285408148 0.0 purine_nucleotide_binding GO:0017076 12133 1650 66 13 1997 23 1 false 0.999308758769392 0.999308758769392 0.0 ribonucleotide_binding GO:0032553 12133 1651 66 13 1997 23 1 false 0.9993263410841479 0.9993263410841479 0.0 cellular_protein_modification_process GO:0006464 12133 2370 66 28 3038 48 2 false 0.9994322417001338 0.9994322417001338 0.0 membrane_part GO:0044425 12133 2995 66 8 10701 66 2 false 0.999452720965863 0.999452720965863 0.0 protein_localization_to_nucleus GO:0034504 12133 233 66 2 516 17 1 false 0.9995346626720466 0.9995346626720466 1.4955266190313754E-153 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 66 10 1587 30 3 false 0.999535542745426 0.999535542745426 0.0 sexual_reproduction GO:0019953 12133 407 66 2 1345 29 1 false 0.9996466031293428 0.9996466031293428 0.0 protein_targeting_to_nucleus GO:0044744 12133 200 66 2 443 19 1 false 0.9998575129341947 0.9998575129341947 9.352491047681514E-132 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 66 23 3220 42 4 false 0.9999350096214824 0.9999350096214824 0.0 multicellular_organismal_reproductive_process GO:0048609 12133 477 66 2 1275 28 2 false 0.9999693550027315 0.9999693550027315 0.0 DNA_binding GO:0003677 12133 2091 66 15 2849 38 1 false 0.9999978812614022 0.9999978812614022 0.0 protein_complex GO:0043234 12133 2976 66 30 3462 52 1 false 0.9999999003624314 0.9999999003624314 0.0 GO:0000000 12133 11221 66 66 0 0 0 true 1.0 1.0 1.0 telomerase_activity GO:0003720 12133 21 66 1 21 1 1 true 1.0 1.0 1.0 lysosome GO:0005764 12133 258 66 3 258 3 1 true 1.0 1.0 1.0 prostaglandin_metabolic_process GO:0006693 12133 24 66 1 24 1 1 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 66 3 307 3 1 true 1.0 1.0 1.0 macrophage_derived_foam_cell_differentiation GO:0010742 12133 26 66 1 26 1 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 66 3 304 3 1 true 1.0 1.0 1.0 cholesterol_transport GO:0030301 12133 50 66 1 50 1 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 66 3 147 3 1 true 1.0 1.0 1.0 slit_diaphragm GO:0036057 12133 6 66 1 6 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 66 2 87 2 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 66 9 1169 9 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 66 12 417 12 1 true 1.0 1.0 1.0 phosphatidylinositol-mediated_signaling GO:0048015 12133 173 66 1 173 1 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 66 2 124 2 2 true 1.0 1.0 1.0 glomerular_visceral_epithelial_cell_differentiation GO:0072112 12133 14 66 1 14 1 2 true 1.0 1.0 1.0