ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min multi-organism_cellular_process GO:0044764 12133 634 35 15 9702 33 2 false 4.946033622494563E-10 4.946033622494563E-10 0.0 ribonucleoprotein_complex GO:0030529 12133 569 35 14 9264 35 2 false 6.47876805841278E-9 6.47876805841278E-9 0.0 macromolecular_complex GO:0032991 12133 3462 35 27 10701 35 1 false 6.626120085971717E-8 6.626120085971717E-8 0.0 cytosolic_part GO:0044445 12133 178 35 9 5117 27 2 false 1.6645173475631826E-7 1.6645173475631826E-7 0.0 multi-organism_process GO:0051704 12133 1180 35 16 10446 34 1 false 1.9316832476397894E-7 1.9316832476397894E-7 0.0 translational_initiation GO:0006413 12133 160 35 7 7667 28 2 false 1.2379567741041354E-6 1.2379567741041354E-6 0.0 ribosomal_subunit GO:0044391 12133 132 35 7 7199 32 4 false 1.3648710927345855E-6 1.3648710927345855E-6 2.5906239763169356E-285 reproductive_process GO:0022414 12133 1275 35 15 10446 34 2 false 3.531903376941596E-6 3.531903376941596E-6 0.0 reproduction GO:0000003 12133 1345 35 15 10446 34 1 false 6.917649074504432E-6 6.917649074504432E-6 0.0 cellular_metabolic_process GO:0044237 12133 7256 35 33 10007 33 2 false 2.4225410918407522E-5 2.4225410918407522E-5 0.0 ribosome GO:0005840 12133 210 35 7 6755 30 3 false 2.8108558875507206E-5 2.8108558875507206E-5 0.0 protein_targeting_to_ER GO:0045047 12133 104 35 6 721 7 3 false 4.9056367635485584E-5 4.9056367635485584E-5 1.514347826459292E-128 translational_elongation GO:0006414 12133 121 35 6 3388 21 2 false 6.406978615133321E-5 6.406978615133321E-5 5.332026529203484E-226 cellular_macromolecule_catabolic_process GO:0044265 12133 672 35 12 6457 33 3 false 6.593018957833694E-5 6.593018957833694E-5 0.0 organelle_part GO:0044422 12133 5401 35 29 10701 35 2 false 7.109312215993193E-5 7.109312215993193E-5 0.0 multi-organism_reproductive_process GO:0044703 12133 707 35 15 1275 15 1 false 1.347707126607265E-4 1.347707126607265E-4 0.0 tRNA-splicing_ligase_complex GO:0072669 12133 5 35 2 9248 35 2 false 1.381640875193095E-4 1.381640875193095E-4 1.775872679278938E-18 protein_targeting GO:0006605 12133 443 35 7 2378 9 2 false 1.8995180896879215E-4 1.8995180896879215E-4 0.0 viral_transcription GO:0019083 12133 145 35 6 2964 19 3 false 1.97638397219051E-4 1.97638397219051E-4 1.0927707330622845E-250 macromolecule_catabolic_process GO:0009057 12133 820 35 12 6846 33 2 false 2.589029081100048E-4 2.589029081100048E-4 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 35 20 10701 35 1 false 2.873329760169504E-4 2.873329760169504E-4 0.0 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 35 2 6481 32 2 false 3.4995911926302605E-4 3.4995911926302605E-4 9.738359623180132E-21 cellular_component_disassembly GO:0022411 12133 351 35 7 7663 31 2 false 4.0367395082909006E-4 4.0367395082909006E-4 0.0 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 35 6 1239 8 2 false 4.6065527669373474E-4 4.6065527669373474E-4 4.427655683668096E-244 structural_constituent_of_ribosome GO:0003735 12133 152 35 6 526 6 1 false 5.422391405504986E-4 5.422391405504986E-4 1.18011379183299E-136 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 35 32 7569 33 2 false 6.364413751446612E-4 6.364413751446612E-4 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 35 6 516 7 1 false 6.649280634756866E-4 6.649280634756866E-4 8.917305549619806E-119 translation GO:0006412 12133 457 35 9 5433 31 3 false 7.321341034888242E-4 7.321341034888242E-4 0.0 cellular_macromolecule_localization GO:0070727 12133 918 35 8 2206 8 2 false 8.833510234813049E-4 8.833510234813049E-4 0.0 nucleus GO:0005634 12133 4764 35 26 7259 28 1 false 8.870235253259518E-4 8.870235253259518E-4 0.0 regulation_of_innate_immune_response GO:0045088 12133 226 35 5 868 5 3 false 0.001157737894082443 0.001157737894082443 2.196344369914344E-215 metabolic_process GO:0008152 12133 8027 35 33 10446 34 1 false 0.001432514531278268 0.001432514531278268 0.0 translational_termination GO:0006415 12133 92 35 6 513 9 2 false 0.0015223185313788796 0.0015223185313788796 3.4634519853301643E-104 chaperone-mediated_protein_complex_assembly GO:0051131 12133 13 35 2 284 2 1 false 0.001940974468720353 0.001940974468720353 1.0524692676806645E-22 RNA_catabolic_process GO:0006401 12133 203 35 6 4368 30 3 false 0.0021769702715707575 0.0021769702715707575 0.0 catabolic_process GO:0009056 12133 2164 35 17 8027 33 1 false 0.0022926173496492907 0.0022926173496492907 0.0 positive_regulation_of_cell_migration_involved_in_sprouting_angiogenesis GO:0090050 12133 5 35 2 93 2 4 false 0.0023375409069658153 0.0023375409069658153 1.9241395291318295E-8 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 35 21 10446 34 1 false 0.0026105759135784034 0.0026105759135784034 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 35 17 7502 33 2 false 0.002743098149118474 0.002743098149118474 0.0 mRNA_metabolic_process GO:0016071 12133 573 35 10 3294 23 1 false 0.0030672979808928124 0.0030672979808928124 0.0 kinase_inhibitor_activity GO:0019210 12133 49 35 2 1377 3 4 false 0.003639108826525448 0.003639108826525448 2.2473743885530668E-91 lipopolysaccharide_receptor_complex GO:0046696 12133 4 35 1 3000 3 3 false 0.003995999556001968 0.003995999556001968 2.9688971292250733E-13 channel_inhibitor_activity GO:0016248 12133 20 35 2 304 2 2 false 0.00412541254125343 0.00412541254125343 1.0141079171115058E-31 protein_complex_disassembly GO:0043241 12133 154 35 6 1031 12 2 false 0.0042907934970878876 0.0042907934970878876 4.7545827865276796E-188 cellular_process_involved_in_reproduction GO:0048610 12133 469 35 6 9699 33 2 false 0.004499857270384511 0.004499857270384511 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 35 26 6846 33 2 false 0.004656029077214955 0.004656029077214955 0.0 ion_channel_inhibitor_activity GO:0008200 12133 20 35 2 286 2 2 false 0.004662004662004078 0.004662004662004078 3.5818833657211076E-31 deacetylase_activity GO:0019213 12133 35 35 2 2556 8 1 false 0.004844570178787927 0.004844570178787927 7.098365746650995E-80 regulation_of_cell_migration_involved_in_sprouting_angiogenesis GO:0090049 12133 11 35 2 147 2 3 false 0.005125337806355226 0.005125337806355226 8.456079340960635E-17 protein_kinase_C_binding GO:0005080 12133 39 35 3 341 4 1 false 0.00513476548807496 0.00513476548807496 3.262596721977534E-52 perikaryon GO:0043204 12133 31 35 2 9983 35 2 false 0.005209654882040988 0.005209654882040988 9.08193271158762E-91 RNA_binding GO:0003723 12133 763 35 10 2849 17 1 false 0.005210684357361041 0.005210684357361041 0.0 cytoplasm GO:0005737 12133 6938 35 33 9083 35 1 false 0.005456548014514111 0.005456548014514111 0.0 viral_reproductive_process GO:0022415 12133 557 35 15 783 15 2 false 0.0057202431359827475 0.0057202431359827475 1.4346997744229993E-203 protein_targeting_to_membrane GO:0006612 12133 145 35 6 443 7 1 false 0.005833036722506728 0.005833036722506728 5.648405296311656E-121 protein_kinase_inhibitor_activity GO:0004860 12133 46 35 2 1016 3 4 false 0.005847673703102618 0.005847673703102618 7.458157078887417E-81 macromolecular_complex_disassembly GO:0032984 12133 199 35 6 1380 13 2 false 0.005929200505005959 0.005929200505005959 1.9082717261040364E-246 intracellular_organelle_part GO:0044446 12133 5320 35 28 9083 35 3 false 0.0063671364155663615 0.0063671364155663615 0.0 cellular_catabolic_process GO:0044248 12133 1972 35 16 7289 33 2 false 0.00682791932341245 0.00682791932341245 0.0 abscission GO:0009838 12133 2 35 1 3447 12 2 false 0.006951463509844412 0.006951463509844412 1.68373383467765E-7 structural_molecule_activity GO:0005198 12133 526 35 6 10257 34 1 false 0.006968211779363516 0.006968211779363516 0.0 intracellular_protein_transport GO:0006886 12133 658 35 7 1672 8 3 false 0.007546078655582866 0.007546078655582866 0.0 nuclear_part GO:0044428 12133 2767 35 20 6936 32 2 false 0.008001386067083994 0.008001386067083994 0.0 phagocytic_cup GO:0001891 12133 11 35 1 1329 1 1 false 0.008276899924748992 0.008276899924748992 1.8213839616773084E-27 cytoplasmic_part GO:0044444 12133 5117 35 27 9083 35 2 false 0.008723816921083132 0.008723816921083132 0.0 regulation_of_RNA_stability GO:0043487 12133 37 35 2 2240 9 2 false 0.008886645607216217 0.008886645607216217 2.0388833014238124E-81 macromolecule_metabolic_process GO:0043170 12133 6052 35 32 7451 33 1 false 0.008920974195590488 0.008920974195590488 0.0 establishment_of_protein_localization GO:0045184 12133 1153 35 8 3010 10 2 false 0.009005578916708763 0.009005578916708763 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 35 6 220 6 2 false 0.010947278694371287 0.010947278694371287 1.3850176335002185E-65 nitrogen_compound_metabolic_process GO:0006807 12133 5244 35 28 8027 33 1 false 0.011130689621625653 0.011130689621625653 0.0 replication_fork_protection_complex GO:0031298 12133 2 35 1 3062 18 3 false 0.011724373830508932 0.011724373830508932 2.133838170991397E-7 organelle GO:0043226 12133 7980 35 32 10701 35 1 false 0.01174895600629293 0.01174895600629293 0.0 kinase_regulator_activity GO:0019207 12133 125 35 2 1851 3 3 false 0.012977004166769439 0.012977004166769439 5.123060762627793E-198 positive_regulation_of_innate_immune_response GO:0045089 12133 178 35 4 740 5 4 false 0.01322711050442507 0.01322711050442507 1.4450011889246649E-176 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 35 28 7341 33 5 false 0.013312051995080197 0.013312051995080197 0.0 death GO:0016265 12133 1528 35 11 8052 29 1 false 0.01331975010497713 0.01331975010497713 0.0 positive_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060265 12133 2 35 1 589 4 7 false 0.013547694120088058 0.013547694120088058 5.774805677789514E-6 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 35 11 2643 13 1 false 0.0149711930478116 0.0149711930478116 0.0 cell_death GO:0008219 12133 1525 35 11 7542 28 2 false 0.01592582284241187 0.01592582284241187 0.0 negative_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060266 12133 3 35 1 738 4 8 false 0.016194034646969342 0.016194034646969342 1.4988203684165303E-8 extracellular_vesicular_exosome GO:0070062 12133 58 35 2 763 3 2 false 0.016221779978618713 0.016221779978618713 1.4131645972383266E-88 Notch_signaling_pathway GO:0007219 12133 113 35 3 1975 10 1 false 0.016287744249539646 0.016287744249539646 2.33429872590278E-187 B_cell_cytokine_production GO:0002368 12133 2 35 1 119 1 2 false 0.01680672268907591 0.01680672268907591 1.4242985329725256E-4 positive_regulation_of_defense_response GO:0031349 12133 229 35 4 1621 8 3 false 0.017062310858743168 0.017062310858743168 6.85443065618377E-286 lipopolysaccharide_binding GO:0001530 12133 10 35 1 571 1 1 false 0.017513134851141525 0.017513134851141525 1.0661534449705395E-21 negative_regulation_of_biological_process GO:0048519 12133 2732 35 15 10446 34 2 false 0.017537268490899902 0.017537268490899902 0.0 cellular_sodium_ion_homeostasis GO:0006883 12133 5 35 1 283 1 3 false 0.017667844522967165 0.017667844522967165 6.84978827344915E-11 positive_regulation_of_cellular_component_movement GO:0051272 12133 216 35 4 3234 16 3 false 0.018618030865299028 0.018618030865299028 0.0 ligase_activity GO:0016874 12133 504 35 5 4901 16 1 false 0.01883971155633042 0.01883971155633042 0.0 vinculin_binding GO:0017166 12133 11 35 1 556 1 1 false 0.01978417266186847 0.01978417266186847 2.809097474179898E-23 channel_regulator_activity GO:0016247 12133 66 35 2 10257 34 2 false 0.020039628705742874 0.020039628705742874 1.2576121117294417E-172 lipid_particle_organization GO:0034389 12133 6 35 1 2031 7 1 false 0.020527165614010523 0.020527165614010523 1.0334354324051953E-17 regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060264 12133 4 35 1 1701 9 6 false 0.021015038051034468 0.021015038051034468 2.8769144126071423E-12 positive_regulation_of_respiratory_burst GO:0060267 12133 5 35 1 1885 8 3 false 0.021062973980885927 0.021062973980885927 5.069092992061398E-15 extracellular_organelle GO:0043230 12133 59 35 2 8358 32 2 false 0.021215095567606552 0.021215095567606552 6.7158083402639515E-152 extracellular_membrane-bounded_organelle GO:0065010 12133 59 35 2 7284 28 2 false 0.02130240961008635 0.02130240961008635 2.3146567535480854E-148 RNA_polymerase_II_core_binding GO:0000993 12133 8 35 1 373 1 3 false 0.021447721179625748 0.021447721179625748 1.1605711850361222E-16 negative_regulation_of_respiratory_burst GO:0060268 12133 3 35 1 1370 10 3 false 0.021754131533916955 0.021754131533916955 2.3385202648234984E-9 cytoplasmic_transport GO:0016482 12133 666 35 7 1148 7 1 false 0.021824640451387985 0.021824640451387985 0.0 macromolecular_complex_subunit_organization GO:0043933 12133 1256 35 12 3745 21 1 false 0.021967566312342295 0.021967566312342295 0.0 negative_regulation_of_cell_growth GO:0030308 12133 117 35 3 2621 14 4 false 0.022005758421847123 0.022005758421847123 6.020174158767381E-207 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 35 28 7451 33 1 false 0.022376656046677774 0.022376656046677774 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 35 7 2370 12 1 false 0.0225572604646695 0.0225572604646695 0.0 positive_regulation_of_biological_process GO:0048518 12133 3081 35 16 10446 34 2 false 0.022676150284004243 0.022676150284004243 0.0 histone_deacetylation GO:0016575 12133 48 35 2 314 2 2 false 0.022954355833210392 0.022954355833210392 7.70276345269051E-58 phosphopyruvate_hydratase_complex GO:0000015 12133 3 35 1 3063 24 2 false 0.023330222878032457 0.023330222878032457 2.0899492370251387E-10 T_cell_mediated_immune_response_to_tumor_cell GO:0002424 12133 1 35 1 42 1 2 false 0.023809523809523944 0.023809523809523944 0.023809523809523944 heterocycle_metabolic_process GO:0046483 12133 4933 35 28 7256 33 1 false 0.02397448758522994 0.02397448758522994 0.0 regulation_of_cell_division GO:0051302 12133 75 35 2 6427 21 2 false 0.02445141708836674 0.02445141708836674 9.599183496643589E-177 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 35 10 2595 13 2 false 0.024464701999639377 0.024464701999639377 0.0 branching_involved_in_labyrinthine_layer_morphogenesis GO:0060670 12133 6 35 1 485 2 3 false 0.024614467069948652 0.024614467069948652 5.706435508639544E-14 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 35 28 7256 33 1 false 0.02462176117835845 0.02462176117835845 0.0 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds GO:0016810 12133 82 35 2 2556 8 1 false 0.02511003502478423 0.02511003502478423 6.720612726716271E-157 ATPase_activity GO:0016887 12133 307 35 4 1069 5 2 false 0.025904293056529564 0.025904293056529564 1.5605649392254874E-277 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 35 12 5462 30 2 false 0.025968145129639648 0.025968145129639648 0.0 embryonic_cleavage GO:0040016 12133 5 35 1 1138 6 2 false 0.026130997879674787 0.026130997879674787 6.342949764440575E-14 regulation_of_response_to_stress GO:0080134 12133 674 35 6 3466 13 2 false 0.026135128398273852 0.026135128398273852 0.0 cellular_protein_localization GO:0034613 12133 914 35 8 1438 8 2 false 0.026340778786013524 0.026340778786013524 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 35 12 5528 30 2 false 0.026583103833717876 0.026583103833717876 0.0 regulation_of_immune_response GO:0050776 12133 533 35 5 2461 9 3 false 0.02707354268398482 0.02707354268398482 0.0 collateral_sprouting GO:0048668 12133 13 35 1 473 1 3 false 0.027484143763211528 0.027484143763211528 1.2397727702664144E-25 heterocycle_catabolic_process GO:0046700 12133 1243 35 12 5392 30 2 false 0.028066576850973374 0.028066576850973374 0.0 negative_regulation_of_cellular_process GO:0048523 12133 2515 35 14 9689 33 3 false 0.028959156556740275 0.028959156556740275 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 35 12 4878 28 5 false 0.02912002314855461 0.02912002314855461 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 35 12 5388 30 2 false 0.02924155012961891 0.02924155012961891 0.0 protein_kinase_regulator_activity GO:0019887 12133 106 35 2 1026 3 3 false 0.02960036014834121 0.02960036014834121 2.0818014646962408E-147 DNA_replication_origin_binding GO:0003688 12133 6 35 1 1189 6 1 false 0.029960395991546276 0.029960395991546276 2.580647819181452E-16 spongiotrophoblast_layer_development GO:0060712 12133 8 35 1 3099 12 2 false 0.03059523998445447 0.03059523998445447 4.782720574858649E-24 negative_regulation_of_metabolic_process GO:0009892 12133 1354 35 10 8327 33 3 false 0.03227151410938707 0.03227151410938707 0.0 histone_deacetylase_complex GO:0000118 12133 50 35 2 3138 18 2 false 0.03235899329215884 0.03235899329215884 6.6201010514053174E-111 positive_regulation_of_cellular_process GO:0048522 12133 2811 35 15 9694 33 3 false 0.0325779763914638 0.0325779763914638 0.0 cytosol GO:0005829 12133 2226 35 17 5117 27 1 false 0.03259552965298332 0.03259552965298332 0.0 protein_deacylation GO:0035601 12133 58 35 2 2370 12 1 false 0.03319357353054207 0.03319357353054207 8.732809717864973E-118 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 35 5 2935 16 1 false 0.03321372387672711 0.03321372387672711 0.0 cyclin-dependent_protein_kinase_activating_kinase_holoenzyme_complex GO:0019907 12133 6 35 1 4399 25 2 false 0.033636697936718564 0.033636697936718564 9.96988681802558E-20 receptor_tyrosine_kinase_binding GO:0030971 12133 31 35 1 918 1 1 false 0.03376906318083766 0.03376906318083766 1.9469822979582718E-58 gene_expression GO:0010467 12133 3708 35 25 6052 32 1 false 0.034029932566925394 0.034029932566925394 0.0 regulation_of_T_cell_mediated_immune_response_to_tumor_cell GO:0002840 12133 1 35 1 29 1 3 false 0.034482758620689634 0.034482758620689634 0.034482758620689634 positive_regulation_of_immune_response GO:0050778 12133 394 35 4 1600 6 4 false 0.03537304628447549 0.03537304628447549 0.0 positive_regulation_of_gastrulation GO:2000543 12133 6 35 1 666 4 3 false 0.03563124494528538 0.03563124494528538 8.439088965235187E-15 DNA_topoisomerase_activity GO:0003916 12133 8 35 1 2199 10 2 false 0.03586258277968662 0.03586258277968662 7.468869718379493E-23 ATP_catabolic_process GO:0006200 12133 318 35 4 1012 5 4 false 0.03612687580692557 0.03612687580692557 1.0026310858617265E-272 intracellular_part GO:0044424 12133 9083 35 35 9983 35 2 false 0.03641811722155644 0.03641811722155644 0.0 ATP_metabolic_process GO:0046034 12133 381 35 4 1209 5 3 false 0.03657251382059828 0.03657251382059828 0.0 negative_regulation_of_phagocytosis GO:0050765 12133 6 35 1 164 1 3 false 0.03658536585365968 0.03658536585365968 4.059224269135992E-11 cellular_response_to_hypoxia GO:0071456 12133 79 35 2 1210 5 3 false 0.03700161441920834 0.03700161441920834 3.484581288071841E-126 negative_regulation_of_sodium_ion_transport GO:0010766 12133 5 35 1 135 1 3 false 0.03703703703703773 0.03703703703703773 2.884335739945468E-9 positive_regulation_of_peptidase_activity GO:0010952 12133 121 35 2 1041 3 3 false 0.037162820260345494 0.037162820260345494 8.90382030646545E-162 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 35 28 7275 33 2 false 0.03830415055544812 0.03830415055544812 0.0 negative_regulation_of_transferase_activity GO:0051348 12133 180 35 2 2118 4 3 false 0.038431068008811096 0.038431068008811096 1.0892582554699503E-266 nucleoside_metabolic_process GO:0009116 12133 1083 35 5 2072 5 4 false 0.03883965745501366 0.03883965745501366 0.0 mitochondrial_membrane GO:0031966 12133 359 35 2 1810 2 3 false 0.039251868344036246 0.039251868344036246 0.0 midbody GO:0030496 12133 90 35 2 9983 35 1 false 0.03945470503718881 0.03945470503718881 2.5893666131724343E-222 heterocyclic_compound_binding GO:1901363 12133 4359 35 21 8962 32 1 false 0.03964558135269959 0.03964558135269959 0.0 regulation_of_establishment_or_maintenance_of_cell_polarity GO:0032878 12133 13 35 1 6318 20 2 false 0.040417315868586524 0.040417315868586524 2.466666500315866E-40 regulation_of_cellular_component_movement GO:0051270 12133 412 35 4 6475 21 3 false 0.04079356958413578 0.04079356958413578 0.0 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 35 2 201 2 3 false 0.04079601990049252 0.04079601990049252 9.949481941404742E-44 water_homeostasis GO:0030104 12133 14 35 1 677 2 1 false 0.04096125440292892 0.04096125440292892 2.3492827505763342E-29 primary_metabolic_process GO:0044238 12133 7288 35 33 8027 33 1 false 0.04101223220384776 0.04101223220384776 0.0 positive_regulation_of_macrophage_activation GO:0043032 12133 9 35 1 219 1 3 false 0.04109589041096042 0.04109589041096042 3.699123120669143E-16 regulation_of_respiratory_burst GO:0060263 12133 9 35 1 4476 21 2 false 0.041477772188452874 0.041477772188452874 5.072797550268562E-28 basal_transcription_machinery_binding GO:0001098 12133 464 35 5 6397 27 1 false 0.04200447587761469 0.04200447587761469 0.0 peptidyl-lysine_deacetylation GO:0034983 12133 5 35 1 229 2 2 false 0.04328506856660663 0.04328506856660663 1.9911047217357908E-10 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 35 2 22 2 1 false 0.04329004329004321 0.04329004329004321 3.79737221842484E-5 positive_regulation_of_T_cell_mediated_immune_response_to_tumor_cell GO:0002842 12133 1 35 1 23 1 4 false 0.043478260869565216 0.043478260869565216 0.043478260869565216 immune_response_to_tumor_cell GO:0002418 12133 9 35 1 1007 5 2 false 0.043981394607003725 0.043981394607003725 3.5323813795745804E-22 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 35 2 1881 5 2 false 0.04428829877217452 0.04428829877217452 3.367676499542027E-210 growth_hormone_receptor_signaling_pathway GO:0060396 12133 26 35 1 587 1 2 false 0.04429301533220136 0.04429301533220136 7.328929196658047E-46 organic_cyclic_compound_binding GO:0097159 12133 4407 35 21 8962 32 1 false 0.04513701207014967 0.04513701207014967 0.0 vasculature_development GO:0001944 12133 441 35 4 2686 9 2 false 0.045442690286561546 0.045442690286561546 0.0 cellular_response_to_oxygen_levels GO:0071453 12133 85 35 2 1663 7 2 false 0.04585711609753839 0.04585711609753839 4.192529980934564E-145 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 35 10 3547 12 1 false 0.04623577376806544 0.04623577376806544 0.0 nuclear_lumen GO:0031981 12133 2490 35 19 3186 20 2 false 0.04715535090063291 0.04715535090063291 0.0 regulation_of_growth GO:0040008 12133 447 35 4 6651 21 2 false 0.0483788534561775 0.0483788534561775 0.0 ligase_activity,_forming_phosphoric_ester_bonds GO:0016886 12133 5 35 1 504 5 1 false 0.048818962551724535 0.048818962551724535 3.764187751563557E-12 regulation_of_cell_differentiation GO:0045595 12133 872 35 6 6612 21 3 false 0.04883403463441033 0.04883403463441033 0.0 respiratory_burst GO:0045730 12133 21 35 1 2877 7 1 false 0.050040600835146075 0.050040600835146075 1.2658513282149024E-53 sprouting_angiogenesis GO:0002040 12133 41 35 2 300 3 1 false 0.050063971628025866 0.050063971628025866 1.6101766178150428E-51 enzyme_binding GO:0019899 12133 1005 35 8 6397 27 1 false 0.05009275590769585 0.05009275590769585 0.0 activation_of_NF-kappaB-inducing_kinase_activity GO:0007250 12133 16 35 1 319 1 5 false 0.050156739811908914 0.050156739811908914 2.6671768240247182E-27 mRNA_catabolic_process GO:0006402 12133 181 35 6 592 10 2 false 0.050215086266164013 0.050215086266164013 1.4563864024176219E-157 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 35 1 3020 26 2 false 0.050597517089443135 0.050597517089443135 9.537822615543818E-19 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 35 7 2771 14 5 false 0.0507976085038123 0.0507976085038123 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 35 18 7980 32 1 false 0.05099187103549471 0.05099187103549471 0.0 intracellular GO:0005622 12133 9171 35 35 9983 35 1 false 0.05106806915768965 0.05106806915768965 0.0 regulation_of_epithelial_cell_migration GO:0010632 12133 90 35 2 1654 7 3 false 0.05142776559537802 0.05142776559537802 3.756993278892793E-151 negative_regulation_of_growth GO:0045926 12133 169 35 3 2922 15 3 false 0.051731491077059426 0.051731491077059426 1.2080528965902671E-279 regulation_of_cell_cycle GO:0051726 12133 659 35 5 6583 21 2 false 0.05206595733348268 0.05206595733348268 0.0 regulation_of_endocytosis GO:0030100 12133 113 35 2 1437 5 3 false 0.05237828146331676 0.05237828146331676 3.3139638850760945E-171 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 35 18 7958 32 2 false 0.05238439059669159 0.05238439059669159 0.0 cytosolic_ribosome GO:0022626 12133 92 35 6 296 10 2 false 0.052684236802532335 0.052684236802532335 4.2784789004852985E-79 chaperonin-containing_T-complex GO:0005832 12133 7 35 1 3063 24 2 false 0.05362692699726897 0.05362692699726897 2.006232217828828E-21 positive_regulation_of_endopeptidase_activity GO:0010950 12133 112 35 2 476 2 3 false 0.05498452012386166 0.05498452012386166 3.786215967470695E-112 execution_phase_of_apoptosis GO:0097194 12133 103 35 2 7541 28 2 false 0.055482803723290744 0.055482803723290744 8.404030944176242E-236 regulation_of_potassium_ion_transmembrane_transport GO:1901379 12133 12 35 1 216 1 3 false 0.05555555555555571 0.05555555555555571 6.338882729411382E-20 intracellular_organelle_lumen GO:0070013 12133 2919 35 20 5320 28 2 false 0.0556990600916723 0.0556990600916723 0.0 negative_regulation_of_interleukin-2_production GO:0032703 12133 8 35 1 143 1 3 false 0.055944055944053495 0.055944055944053495 2.8144635666603867E-13 protein_complex_subunit_organization GO:0071822 12133 989 35 12 1256 12 1 false 0.05601131550008343 0.05601131550008343 2.2763776011987297E-281 respiratory_burst_involved_in_defense_response GO:0002679 12133 9 35 1 1100 7 3 false 0.05603522040195152 0.05603522040195152 1.590299388551981E-22 cell_differentiation_involved_in_embryonic_placenta_development GO:0060706 12133 18 35 1 2166 7 2 false 0.056818187371207154 0.056818187371207154 6.240927585059501E-45 negative_regulation_of_kinase_activity GO:0033673 12133 172 35 2 1181 3 3 false 0.05722970187498035 0.05722970187498035 3.9159843646516213E-212 adipose_tissue_development GO:0060612 12133 19 35 1 1929 6 2 false 0.05773474090212248 0.05773474090212248 5.039701939128339E-46 unfolded_protein_binding GO:0051082 12133 93 35 2 6397 27 1 false 0.058020008883665534 0.058020008883665534 2.507796527596117E-210 production_of_molecular_mediator_involved_in_inflammatory_response GO:0002532 12133 18 35 1 4184 14 2 false 0.05866250778722151 0.05866250778722151 4.3012458861645E-50 regulation_of_potassium_ion_transmembrane_transporter_activity GO:1901016 12133 9 35 1 153 1 3 false 0.05882352941176151 0.05882352941176151 1.0038611131963863E-14 positive_regulation_of_response_to_biotic_stimulus GO:0002833 12133 12 35 1 1380 7 3 false 0.05943043608791216 0.05943043608791216 1.0534561678124694E-29 regulation_of_macrophage_activation GO:0043030 12133 17 35 1 286 1 2 false 0.05944055944056004 0.05944055944056004 1.007984081953719E-27 positive_regulation_of_cell_motility GO:2000147 12133 210 35 3 790 4 4 false 0.05968004107632495 0.05968004107632495 6.640105808226973E-198 regulation_of_metabolic_process GO:0019222 12133 4469 35 21 9189 33 2 false 0.059841206997815845 0.059841206997815845 0.0 multivesicular_body_sorting_pathway GO:0071985 12133 17 35 1 2490 9 2 false 0.05988785872594531 0.05988785872594531 6.909596477174519E-44 intracellular_transport GO:0046907 12133 1148 35 7 2815 10 2 false 0.060467875636925315 0.060467875636925315 0.0 labyrinthine_layer_morphogenesis GO:0060713 12133 13 35 1 422 2 3 false 0.06073330256328421 0.06073330256328421 5.5756487255878705E-25 stress_granule_assembly GO:0034063 12133 9 35 1 291 2 2 false 0.06100248844648582 0.06100248844648582 2.7477938680697565E-17 DNA_replication_checkpoint GO:0000076 12133 8 35 1 130 1 1 false 0.061538461538460855 0.061538461538460855 6.156961182158343E-13 regulation_of_NIK/NF-kappaB_cascade GO:1901222 12133 17 35 1 1605 6 2 false 0.06198622291334689 0.06198622291334689 1.2442844653745033E-40 placenta_development GO:0001890 12133 109 35 2 2873 11 2 false 0.06273859727470622 0.06273859727470622 1.2650587306513289E-200 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 35 2 1056 6 3 false 0.06345678537738014 0.06345678537738014 4.764817151311381E-118 NIK/NF-kappaB_cascade GO:0038061 12133 24 35 1 1828 5 2 false 0.0640124979865541 0.0640124979865541 3.725046499789671E-55 blood_vessel_development GO:0001568 12133 420 35 4 3152 12 3 false 0.06408076417882287 0.06408076417882287 0.0 regulation_of_immune_response_to_tumor_cell GO:0002837 12133 7 35 1 534 5 3 false 0.06408124641662033 0.06408124641662033 4.234386075574407E-16 regulation_of_defense_response GO:0031347 12133 387 35 5 1253 8 2 false 0.06451984229414795 0.06451984229414795 0.0 negative_regulation_of_protein_kinase_activity GO:0006469 12133 163 35 2 1050 3 4 false 0.06455554596834276 0.06455554596834276 4.119509868513009E-196 regulation_of_ligase_activity GO:0051340 12133 98 35 2 2061 9 2 false 0.06478049272150692 0.06478049272150692 1.6310105681359867E-170 positive_regulation_of_sodium_ion_transport GO:0010765 12133 11 35 1 166 1 3 false 0.06626506024096748 0.06626506024096748 2.123209741249517E-17 cytoplasmic_dynein_complex GO:0005868 12133 13 35 1 5120 27 2 false 0.06650248721731845 0.06650248721731845 3.8053308288659296E-39 U12-type_spliceosomal_complex GO:0005689 12133 24 35 2 150 3 1 false 0.0667513150734652 0.0667513150734652 2.5760759444825708E-28 embryonic_placenta_morphogenesis GO:0060669 12133 15 35 1 442 2 2 false 0.06679594914889936 0.06679594914889936 3.4632361194894254E-28 positive_regulation_of_cell_migration GO:0030335 12133 206 35 3 736 4 3 false 0.0687599054252811 0.0687599054252811 9.676188091528093E-189 positive_regulation_of_immune_response_to_tumor_cell GO:0002839 12133 7 35 1 396 4 4 false 0.06910961868564369 0.06910961868564369 3.4811445025267025E-15 positive_regulation_of_angiogenesis GO:0045766 12133 71 35 2 774 5 3 false 0.06917883899247053 0.06917883899247053 1.852564870808831E-102 14-3-3_protein_binding GO:0071889 12133 17 35 1 6397 27 1 false 0.06946398950716755 0.06946398950716755 7.222899753868919E-51 interspecies_interaction_between_organisms GO:0044419 12133 417 35 9 1180 16 1 false 0.06963044935252147 0.06963044935252147 0.0 NF-kappaB-inducing_kinase_activity GO:0004704 12133 21 35 1 301 1 2 false 0.06976744186045904 0.06976744186045904 9.301787616944151E-33 NLS-bearing_substrate_import_into_nucleus GO:0006607 12133 14 35 1 200 1 1 false 0.06999999999999724 0.06999999999999724 8.476072934217597E-22 protein_binding GO:0005515 12133 6397 35 27 8962 32 1 false 0.07037525420461983 0.07037525420461983 0.0 regulation_of_collateral_sprouting GO:0048670 12133 10 35 1 141 1 4 false 0.0709219858156048 0.0709219858156048 1.6195650020747043E-15 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 35 8 4429 22 3 false 0.07129789930365034 0.07129789930365034 0.0 protein_metabolic_process GO:0019538 12133 3431 35 20 7395 33 2 false 0.07147093278920141 0.07147093278920141 0.0 tissue_migration GO:0090130 12133 131 35 2 4095 14 1 false 0.07190371352990425 0.07190371352990425 4.3202440607580954E-251 ribonucleoprotein_granule GO:0035770 12133 75 35 2 3365 20 2 false 0.07192246962818692 0.07192246962818692 1.704323678285534E-155 protein_localization_to_organelle GO:0033365 12133 516 35 7 914 8 1 false 0.07310534987478283 0.07310534987478283 5.634955900168089E-271 positive_regulation_of_locomotion GO:0040017 12133 216 35 3 3440 16 3 false 0.0745937675907133 0.0745937675907133 0.0 protein_binding_transcription_factor_activity GO:0000988 12133 488 35 4 10311 34 3 false 0.07502081690518606 0.07502081690518606 0.0 regulation_of_protein_ubiquitination GO:0031396 12133 176 35 3 1344 8 2 false 0.07502747818503405 0.07502747818503405 8.0617715234352E-226 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 35 3 803 4 1 false 0.07505988120872618 0.07505988120872618 7.141936114023743E-209 IkappaB_kinase_complex GO:0008385 12133 10 35 1 3063 24 2 false 0.07575621364757151 0.07575621364757151 5.066173975414688E-29 positive_regulation_of_cation_channel_activity GO:2001259 12133 17 35 1 224 1 3 false 0.07589285714285353 0.07589285714285353 7.366387194248368E-26 neuromuscular_process GO:0050905 12133 68 35 1 894 1 1 false 0.07606263982101535 0.07606263982101535 6.903742022384109E-104 activation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0006919 12133 81 35 2 1375 8 3 false 0.07615445217619005 0.07615445217619005 4.023711257429167E-133 eukaryotic_translation_initiation_factor_3_complex GO:0005852 12133 16 35 1 6481 32 2 false 0.07622602464471089 0.07622602464471089 2.1998593675926732E-48 cell_division GO:0051301 12133 438 35 4 7541 28 1 false 0.07623808669145948 0.07623808669145948 0.0 regulation_of_cell_growth GO:0001558 12133 243 35 3 1344 6 3 false 0.07628620240983286 0.07628620240983286 4.9010314548000585E-275 positive_regulation_of_ligase_activity GO:0051351 12133 84 35 2 1424 8 3 false 0.07635423816694675 0.07635423816694675 5.130084211911676E-138 'de_novo'_protein_folding GO:0006458 12133 51 35 2 183 2 1 false 0.07656278148080696 0.07656278148080696 1.4322240237766098E-46 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 35 8 4298 22 4 false 0.07674089968632271 0.07674089968632271 0.0 maturation_of_SSU-rRNA GO:0030490 12133 8 35 1 104 1 2 false 0.0769230769230749 0.0769230769230749 3.8823564737710265E-12 excretion GO:0007588 12133 50 35 1 1272 2 1 false 0.07710093077804782 0.07710093077804782 4.8139348402185623E-91 negative_regulation_of_axonogenesis GO:0050771 12133 37 35 1 476 1 4 false 0.07773109243698914 0.07773109243698914 4.910014637903182E-56 telomeric_DNA_binding GO:0042162 12133 16 35 1 1189 6 1 false 0.07823125407438955 0.07823125407438955 1.4512187070438412E-36 Prp19_complex GO:0000974 12133 78 35 2 2976 18 1 false 0.0791637757502989 0.0791637757502989 3.570519754703887E-156 nucleolus_organization GO:0007000 12133 5 35 1 62 1 1 false 0.08064516129032337 0.08064516129032337 1.545355726980193E-7 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 35 9 7606 33 4 false 0.08165097360402228 0.08165097360402228 0.0 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 35 4 673 4 2 false 0.08214961222384984 0.08214961222384984 4.9348138289436974E-201 regulation_of_response_to_tumor_cell GO:0002834 12133 7 35 1 84 1 2 false 0.08333333333333484 0.08333333333333484 2.2078146245082712E-10 rhythmic_process GO:0048511 12133 148 35 2 10446 34 1 false 0.08333883706100995 0.08333883706100995 0.0 positive_regulation_of_protein_homooligomerization GO:0032464 12133 8 35 1 188 2 3 false 0.0835134827625343 0.0835134827625343 3.004813483652656E-14 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 35 4 374 4 2 false 0.08393309066846431 0.08393309066846431 2.0954491420584897E-111 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 35 7 2560 8 2 false 0.08396446113175106 0.08396446113175106 0.0 cellular_response_to_heat GO:0034605 12133 20 35 1 1149 5 2 false 0.08419622028037022 0.08419622028037022 1.7862787837451001E-43 response_to_biotic_stimulus GO:0009607 12133 494 35 4 5200 18 1 false 0.08436152434183271 0.08436152434183271 0.0 positive_regulation_of_blood_vessel_endothelial_cell_migration GO:0043536 12133 21 35 2 71 2 3 false 0.08450704225352176 0.08450704225352176 1.8270708961531386E-18 negative_regulation_of_neurogenesis GO:0050768 12133 81 35 1 956 1 3 false 0.0847280334727849 0.0847280334727849 7.263496623051508E-120 cellular_monovalent_inorganic_cation_homeostasis GO:0030004 12133 26 35 1 306 1 2 false 0.08496732026142838 0.08496732026142838 2.8281153145438213E-38 organic_substance_metabolic_process GO:0071704 12133 7451 35 33 8027 33 1 false 0.08523310848958106 0.08523310848958106 0.0 RNA_metabolic_process GO:0016070 12133 3294 35 23 5627 32 2 false 0.08568274021244768 0.08568274021244768 0.0 response_to_tumor_cell GO:0002347 12133 11 35 1 494 4 1 false 0.08639173528686019 0.08639173528686019 1.0443790780705399E-22 nucleic_acid_binding GO:0003676 12133 2849 35 17 4407 21 2 false 0.08649949427621353 0.08649949427621353 0.0 sodium_ion_homeostasis GO:0055078 12133 26 35 1 299 1 2 false 0.08695652173913307 0.08695652173913307 5.299686091705976E-38 regulation_of_establishment_of_protein_localization_to_plasma_membrane GO:0090003 12133 23 35 1 1525 6 4 false 0.08728547480960819 0.08728547480960819 1.8607806078740915E-51 cell_part GO:0044464 12133 9983 35 35 10701 35 2 false 0.08760806904019375 0.08760806904019375 0.0 cell GO:0005623 12133 9984 35 35 10701 35 1 false 0.08791626910248015 0.08791626910248015 0.0 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 35 6 174 6 1 false 0.08852939047541054 0.08852939047541054 2.5039480990851377E-47 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 35 2 227 2 2 false 0.0888074539004326 0.0888074539004326 1.1311225924750782E-59 negative_regulation_of_protein_kinase_B_signaling_cascade GO:0051898 12133 19 35 1 213 1 3 false 0.08920187793427337 0.08920187793427337 1.6036055676646614E-27 organelle_lumen GO:0043233 12133 2968 35 20 5401 29 2 false 0.08986634639603898 0.08986634639603898 0.0 negative_regulation_of_protein_tyrosine_kinase_activity GO:0061099 12133 15 35 1 326 2 4 false 0.09004247286454344 0.09004247286454344 3.632762065016979E-26 M_band GO:0031430 12133 13 35 1 144 1 2 false 0.09027777777777748 0.09027777777777748 9.504489448794718E-19 DNA_topological_change GO:0006265 12133 9 35 1 194 2 1 false 0.09086053095453998 0.09086053095453998 1.1254898761359862E-15 negative_regulation_of_collateral_sprouting_in_absence_of_injury GO:0048698 12133 1 35 1 11 1 3 false 0.09090909090909105 0.09090909090909105 0.09090909090909105 ribosomal_small_subunit_assembly GO:0000028 12133 6 35 1 128 2 3 false 0.09190452755905432 0.09190452755905432 1.8437899825856603E-10 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 35 5 5830 21 3 false 0.09213885532939949 0.09213885532939949 0.0 tRNA_splicing,_via_endonucleolytic_cleavage_and_ligation GO:0006388 12133 6 35 1 65 1 2 false 0.09230769230769148 0.09230769230769148 1.2106701688933283E-8 DNA_replication_preinitiation_complex GO:0031261 12133 28 35 1 877 3 3 false 0.09285815591754651 0.09285815591754651 1.8592053486968803E-53 immune_response-regulating_signaling_pathway GO:0002764 12133 310 35 3 3626 13 2 false 0.09313349568142837 0.09313349568142837 0.0 cell_cycle GO:0007049 12133 1295 35 8 7541 28 1 false 0.09339634532676959 0.09339634532676959 0.0 replication_fork GO:0005657 12133 48 35 1 512 1 1 false 0.09374999999998292 0.09374999999998292 1.088424225361165E-68 cytoplasmic_mRNA_processing_body_assembly GO:0033962 12133 14 35 1 291 2 2 false 0.09406327763951139 0.09406327763951139 3.835897647558033E-24 RNA_splicing,_via_endonucleolytic_cleavage_and_ligation GO:0000394 12133 6 35 1 307 5 1 false 0.09456808497337485 0.09456808497337485 9.033367942605732E-13 regulation_of_insulin_receptor_signaling_pathway GO:0046626 12133 28 35 1 1672 6 3 false 0.09650295779639763 0.09650295779639763 2.1490757988750073E-61 cell_growth GO:0016049 12133 299 35 3 7559 28 2 false 0.09704384574767316 0.09704384574767316 0.0 substrate_adhesion-dependent_cell_spreading GO:0034446 12133 35 35 1 703 2 2 false 0.09716193926720001 0.09716193926720001 5.553109353087871E-60 negative_regulation_of_innate_immune_response GO:0045824 12133 14 35 1 685 5 4 false 0.09837307264201203 0.09837307264201203 1.989838073929195E-29 negative_regulation_of_nuclear_division GO:0051784 12133 43 35 1 436 1 3 false 0.0986238532109988 0.0986238532109988 1.634686522119006E-60 nuclear_pre-replicative_complex GO:0005656 12133 28 35 1 821 3 4 false 0.09898101660667025 0.09898101660667025 1.2155097168867057E-52 type_I_interferon_production GO:0032606 12133 71 35 2 362 3 1 false 0.09951510792101192 0.09951510792101192 2.8677775679244762E-77 defense_response GO:0006952 12133 1018 35 7 2540 11 1 false 0.09983646019506581 0.09983646019506581 0.0 negative_regulation_of_ion_transport GO:0043271 12133 50 35 1 974 2 3 false 0.10008420368435042 0.10008420368435042 4.081641839466338E-85 double-stranded_RNA_binding GO:0003725 12133 42 35 2 763 10 1 false 0.10056709533835645 0.10056709533835645 3.809412344480898E-70 regulation_of_developmental_process GO:0050793 12133 1233 35 7 7209 24 2 false 0.10138786695269035 0.10138786695269035 0.0 cell_migration_involved_in_sprouting_angiogenesis GO:0002042 12133 22 35 2 68 2 2 false 0.10140474100087885 0.10140474100087885 2.4938962391792082E-18 cell-cell_junction_assembly GO:0007043 12133 58 35 2 181 2 2 false 0.10147329650091381 0.10147329650091381 7.851737058026464E-49 sodium_channel_activity GO:0005272 12133 26 35 1 256 1 3 false 0.10156249999999863 0.10156249999999863 3.647595212320824E-36 regulation_of_DNA-dependent_DNA_replication_initiation GO:0030174 12133 5 35 1 49 1 2 false 0.10204081632653168 0.10204081632653168 5.244157484146837E-7 negative_regulation_of_endocytosis GO:0045806 12133 23 35 1 859 4 4 false 0.10304890026119617 0.10304890026119617 1.1473487217608225E-45 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 35 20 5597 28 2 false 0.10347673545858443 0.10347673545858443 0.0 single-stranded_DNA_binding GO:0003697 12133 58 35 2 179 2 1 false 0.10375996484840343 0.10375996484840343 1.7047154028422047E-48 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 35 2 695 5 3 false 0.10392391312398955 0.10392391312398955 3.5521820546065696E-107 regulation_of_cellular_response_to_insulin_stimulus GO:1900076 12133 35 35 1 6377 20 3 false 0.10437778544288054 0.10437778544288054 7.820828556986838E-94 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 35 2 676 7 2 false 0.10476662527627534 0.10476662527627534 2.737610529852072E-82 DNA_catabolic_process,_endonucleolytic GO:0000737 12133 27 35 1 257 1 2 false 0.10505836575875643 0.10505836575875643 3.832103919558655E-37 U2_snRNP GO:0005686 12133 5 35 1 93 2 1 false 0.10518934081346172 0.10518934081346172 1.9241395291318295E-8 regulation_of_immune_system_process GO:0002682 12133 794 35 5 6789 22 2 false 0.10566115497495485 0.10566115497495485 0.0 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 35 8 3780 22 4 false 0.10624181544393418 0.10624181544393418 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 35 20 5588 28 2 false 0.10632337450051244 0.10632337450051244 0.0 histone_H4_deacetylation GO:0070933 12133 16 35 2 48 2 1 false 0.10638297872340371 0.10638297872340371 4.4348869405293416E-13 macromolecule_biosynthetic_process GO:0009059 12133 3475 35 21 6537 32 2 false 0.10697410248398137 0.10697410248398137 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 35 8 3453 21 4 false 0.1070707130452136 0.1070707130452136 0.0 angiogenesis GO:0001525 12133 300 35 3 2776 11 3 false 0.10712514153751834 0.10712514153751834 0.0 phosphopyruvate_hydratase_activity GO:0004634 12133 3 35 1 28 1 1 false 0.10714285714285729 0.10714285714285729 3.052503052503051E-4 peptidase_activator_activity GO:0016504 12133 33 35 1 885 3 4 false 0.10786240459739065 0.10786240459739065 8.951452456901943E-61 positive_regulation_of_transporter_activity GO:0032411 12133 34 35 1 2101 7 4 false 0.10807278042505311 0.10807278042505311 4.2098203958278254E-75 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 35 20 5686 28 2 false 0.1080768596105358 0.1080768596105358 0.0 regulation_of_type_I_interferon_production GO:0032479 12133 67 35 2 325 3 2 false 0.10908117453008048 0.10908117453008048 2.788484219003069E-71 nuclear_replication_fork GO:0043596 12133 28 35 1 256 1 3 false 0.10937499999999821 0.10937499999999821 5.235583786811974E-38 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 35 2 1663 7 2 false 0.11028806515695493 0.11028806515695493 7.181952736648417E-207 ribosome_assembly GO:0042255 12133 16 35 1 417 3 3 false 0.11100406051433201 0.11100406051433201 3.349634512578164E-29 CMG_complex GO:0071162 12133 28 35 1 251 1 4 false 0.11155378486055467 0.11155378486055467 9.388589672695531E-38 positive_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043280 12133 101 35 2 1376 8 3 false 0.11174146938188309 0.11174146938188309 4.055423334241229E-156 labyrinthine_layer_development GO:0060711 12133 31 35 1 3152 12 3 false 0.11202616030511013 0.11202616030511013 3.3352347986707567E-75 signal_sequence_binding GO:0005048 12133 20 35 1 178 1 1 false 0.11235955056180288 0.11235955056180288 7.23132468780732E-27 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 35 20 5629 28 2 false 0.11241806748260605 0.11241806748260605 0.0 response_to_virus GO:0009615 12133 230 35 3 475 3 1 false 0.11276259801429628 0.11276259801429628 3.548520767075247E-142 RNA_polymerase_binding GO:0070063 12133 15 35 1 1005 8 1 false 0.11372436712250283 0.11372436712250283 1.3477288899053611E-33 GINS_complex GO:0000811 12133 28 35 1 244 1 2 false 0.1147540983606434 0.1147540983606434 2.171851500338737E-37 positive_regulation_of_ion_transmembrane_transporter_activity GO:0032414 12133 28 35 1 473 2 3 false 0.1150069874941671 0.1150069874941671 8.750359231366189E-46 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 35 3 305 3 2 false 0.1153849768065649 0.1153849768065649 3.640759676212702E-91 protein_deneddylation GO:0000338 12133 9 35 1 77 1 1 false 0.1168831168831165 0.1168831168831165 6.198761061406022E-12 vacuolar_protein_catabolic_process GO:0007039 12133 10 35 1 409 5 1 false 0.11696113407851448 0.11696113407851448 3.095189671373722E-20 positive_regulation_of_immune_effector_process GO:0002699 12133 87 35 2 706 5 3 false 0.11717345112785323 0.11717345112785323 7.573271162497966E-114 regulation_of_kinase_activity GO:0043549 12133 654 35 3 1335 3 3 false 0.11729278023070014 0.11729278023070014 0.0 negative_regulation_of_insulin_receptor_signaling_pathway GO:0046627 12133 21 35 1 685 4 4 false 0.11734841555459057 0.11734841555459057 1.9648603303249254E-40 positive_regulation_of_interleukin-10_production GO:0032733 12133 11 35 1 182 2 3 false 0.11753991864488877 0.11753991864488877 7.485355579391548E-18 embryo_development GO:0009790 12133 768 35 5 3347 12 3 false 0.11782685889999685 0.11782685889999685 0.0 regulation_of_vesicle-mediated_transport GO:0060627 12133 196 35 2 6585 20 3 false 0.1180724136032523 0.1180724136032523 0.0 RNA_splicing GO:0008380 12133 307 35 5 601 6 1 false 0.11864019476184315 0.11864019476184315 4.262015823312228E-180 positive_regulation_of_protein_oligomerization GO:0032461 12133 15 35 1 363 3 3 false 0.11923018984576098 0.11923018984576098 7.002118429057617E-27 cytokine_production GO:0001816 12133 362 35 3 4095 14 1 false 0.12021710641857251 0.12021710641857251 0.0 histone_H3_deacetylation GO:0070932 12133 17 35 2 48 2 1 false 0.12056737588652364 0.12056737588652364 2.356033687156231E-13 ATP_binding GO:0005524 12133 1212 35 7 1638 7 3 false 0.12088096596679415 0.12088096596679415 0.0 outer_membrane GO:0019867 12133 112 35 1 4398 5 1 false 0.12106069477717314 0.12106069477717314 7.412183245910406E-226 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 35 2 1130 4 2 false 0.12152712975945293 0.12152712975945293 1.9819409219356823E-214 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 35 2 987 6 2 false 0.12245068315232713 0.12245068315232713 9.48284116235963E-143 biosynthetic_process GO:0009058 12133 4179 35 21 8027 33 1 false 0.12285258375946181 0.12285258375946181 0.0 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 35 6 145 6 1 false 0.12300365486559368 0.12300365486559368 1.7288474062512548E-37 cellular_protein_catabolic_process GO:0044257 12133 409 35 5 3174 21 3 false 0.12338949816117167 0.12338949816117167 0.0 negative_regulation_of_cellular_response_to_insulin_stimulus GO:1900077 12133 23 35 1 2630 15 4 false 0.12375469566330824 0.12375469566330824 6.243239604942312E-57 regulation_of_locomotion GO:0040012 12133 398 35 3 6714 21 2 false 0.1247806684416814 0.1247806684416814 0.0 intracellular_protein_kinase_cascade GO:0007243 12133 806 35 4 1813 5 1 false 0.1255164420500911 0.1255164420500911 0.0 ubiquitin-dependent_protein_catabolic_process_via_the_multivesicular_body_sorting_pathway GO:0043162 12133 10 35 1 379 5 3 false 0.125775997381375 0.125775997381375 6.689174917849262E-20 fibroblast_growth_factor_binding GO:0017134 12133 17 35 1 135 1 1 false 0.12592592592592816 0.12592592592592816 6.193063943061966E-22 response_to_peptide GO:1901652 12133 322 35 2 904 2 2 false 0.1266207038486307 0.1266207038486307 7.8711156655671515E-255 enzyme_inhibitor_activity GO:0004857 12133 240 35 2 1075 3 2 false 0.12700548657865027 0.12700548657865027 4.258934911432728E-247 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 35 1 1977 7 3 false 0.13036565431109964 0.13036565431109964 8.49513097758148E-83 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 35 3 7778 31 4 false 0.13066444407502636 0.13066444407502636 0.0 adenyl_ribonucleotide_binding GO:0032559 12133 1231 35 7 1645 7 2 false 0.13085029958120353 0.13085029958120353 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 35 7 1650 7 1 false 0.13104425803413922 0.13104425803413922 0.0 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 35 6 1541 12 3 false 0.1315589827686962 0.1315589827686962 0.0 positive_regulation_of_apoptotic_process GO:0043065 12133 362 35 4 1377 8 3 false 0.13178515176527766 0.13178515176527766 0.0 homeostasis_of_number_of_cells GO:0048872 12133 166 35 2 990 4 1 false 0.13299872798134393 0.13299872798134393 1.128853988781411E-193 cell_cycle_process GO:0022402 12133 953 35 6 7541 28 2 false 0.13334650319761643 0.13334650319761643 0.0 BMP_signaling_pathway GO:0030509 12133 83 35 2 1276 10 2 false 0.13396712647451553 0.13396712647451553 9.874891335860256E-133 multi-organism_transport GO:0044766 12133 29 35 1 3441 17 2 false 0.13429966187734754 0.13429966187734754 2.716860412473803E-72 regulation_of_potassium_ion_transport GO:0043266 12133 32 35 1 238 1 2 false 0.13445378151259108 0.13445378151259108 2.0777607490676014E-40 positive_regulation_of_epithelial_cell_migration GO:0010634 12133 62 35 2 268 3 3 false 0.1347173484608618 0.1347173484608618 1.921249223488317E-62 regulation_of_cation_channel_activity GO:2001257 12133 33 35 1 244 1 2 false 0.13524590163933084 0.13524590163933084 1.3783310605710322E-41 histone_deacetylase_activity_(H3-K14_specific) GO:0031078 12133 11 35 2 29 2 2 false 0.13546798029556703 0.13546798029556703 2.890399797209533E-8 spliceosomal_complex GO:0005681 12133 150 35 3 3020 26 2 false 0.1358982232464459 0.1358982232464459 2.455159410572961E-258 sodium_channel_inhibitor_activity GO:0019871 12133 3 35 1 43 2 3 false 0.1362126245847177 0.1362126245847177 8.103071063933269E-5 protein_tyrosine_kinase_inhibitor_activity GO:0030292 12133 4 35 1 57 2 2 false 0.1365914786967431 0.1365914786967431 2.5315814789499106E-6 cysteine-type_endopeptidase_regulator_activity_involved_in_apoptotic_process GO:0043028 12133 42 35 1 876 3 2 false 0.1371987085043845 0.1371987085043845 9.914452505375347E-73 regulation_of_tight_junction_assembly GO:2000810 12133 8 35 1 58 1 2 false 0.13793103448276028 0.13793103448276028 5.217035699399583E-10 positive_regulation_of_apoptotic_signaling_pathway GO:2001235 12133 47 35 1 973 3 3 false 0.13816057807143814 0.13816057807143814 2.8956045317480326E-81 negative_regulation_of_signal_transduction GO:0009968 12133 571 35 4 3588 13 5 false 0.1389332879972877 0.1389332879972877 0.0 negative_regulation_of_translation GO:0017148 12133 61 35 2 1470 16 4 false 0.14011942237156158 0.14011942237156158 1.1152524521517982E-109 regulation_of_nuclear_division GO:0051783 12133 100 35 1 712 1 2 false 0.14044943820226646 0.14044943820226646 7.811073934054147E-125 regulation_of_protein_oligomerization GO:0032459 12133 22 35 1 447 3 2 false 0.1408029817364477 0.1408029817364477 9.37826543019211E-38 regulation_of_transcription_involved_in_G1/S_phase_of_mitotic_cell_cycle GO:0000083 12133 23 35 1 1971 13 3 false 0.1419225731071115 0.1419225731071115 4.905259542985714E-54 cellular_protein_metabolic_process GO:0044267 12133 3038 35 20 5899 32 2 false 0.14193917692858882 0.14193917692858882 0.0 cytoplasmic_stress_granule GO:0010494 12133 29 35 1 5117 27 2 false 0.14259674667864092 0.14259674667864092 2.627932865737447E-77 negative_regulation_of_collateral_sprouting GO:0048671 12133 7 35 1 141 3 5 false 0.14262972600643078 0.14262972600643078 5.291712702278886E-12 regulation_of_protein_homooligomerization GO:0032462 12133 14 35 1 189 2 2 false 0.14302600472811533 0.14302600472811533 1.9240310274561344E-21 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 35 2 207 2 2 false 0.1445054171943169 0.1445054171943169 2.976076769798144E-59 regulation_of_response_to_stimulus GO:0048583 12133 2074 35 9 7292 22 2 false 0.14465116149443386 0.14465116149443386 0.0 regulation_of_peptidase_activity GO:0052547 12133 276 35 2 1151 3 2 false 0.14467610183444343 0.14467610183444343 1.6233323078676786E-274 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 35 5 742 6 2 false 0.14475630470676554 0.14475630470676554 9.121396596563632E-222 immune_system_process GO:0002376 12133 1618 35 8 10446 34 1 false 0.14476382485199538 0.14476382485199538 0.0 A_band GO:0031672 12133 21 35 1 144 1 2 false 0.14583333333333287 0.14583333333333287 1.1180779841874147E-25 positive_regulation_of_endothelial_cell_migration GO:0010595 12133 45 35 2 117 2 3 false 0.14588859416445482 0.14588859416445482 1.8451178464107226E-33 regulation_of_axonogenesis GO:0050770 12133 80 35 1 547 1 3 false 0.1462522851919484 0.1462522851919484 2.8567886122859797E-98 kinase_binding GO:0019900 12133 384 35 5 1005 8 1 false 0.1462597050691177 0.1462597050691177 2.0091697589355545E-289 macromolecule_localization GO:0033036 12133 1642 35 8 3467 12 1 false 0.14646423095670041 0.14646423095670041 0.0 protein_refolding GO:0042026 12133 14 35 1 183 2 1 false 0.14754098360654258 0.14754098360654258 3.073045199995708E-21 negative_regulation_of_cell_communication GO:0010648 12133 599 35 4 4860 17 3 false 0.14822709231188297 0.14822709231188297 0.0 repressing_transcription_factor_binding GO:0070491 12133 207 35 3 715 5 1 false 0.14873181575658698 0.14873181575658698 4.3536836236667346E-186 regulation_of_establishment_of_cell_polarity GO:2000114 12133 10 35 1 67 1 2 false 0.1492537313432855 0.1492537313432855 4.0323445542745576E-12 regulation_of_protein_kinase_activity GO:0045859 12133 621 35 3 1169 3 3 false 0.1495704253511343 0.1495704253511343 0.0 glycolysis GO:0006096 12133 56 35 1 374 1 2 false 0.14973262032084086 0.14973262032084086 4.51855378952521E-68 transcription_corepressor_activity GO:0003714 12133 180 35 3 479 4 2 false 0.15147024707987866 0.15147024707987866 5.2319775680795235E-137 histone_deacetylase_activity GO:0004407 12133 26 35 2 66 2 3 false 0.15151515151515094 0.15151515151515094 6.044910921634578E-19 histone_deacetylase_activity_(H4-K16_specific) GO:0034739 12133 12 35 2 30 2 2 false 0.15172413793103454 0.15172413793103454 1.1561599188838122E-8 regulation_of_protein_catabolic_process GO:0042176 12133 150 35 2 1912 9 3 false 0.1530534757153534 0.1530534757153534 1.3832082048306078E-227 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 35 21 6146 32 3 false 0.15401024615071807 0.15401024615071807 0.0 cardiovascular_system_development GO:0072358 12133 655 35 4 2686 9 2 false 0.15408232788382092 0.15408232788382092 0.0 circulatory_system_development GO:0072359 12133 655 35 4 2686 9 1 false 0.15408232788382092 0.15408232788382092 0.0 regulation_of_gastrulation GO:0010470 12133 25 35 1 605 4 3 false 0.1556858024704834 0.1556858024704834 7.329615892350187E-45 cellular_response_to_peptide GO:1901653 12133 247 35 2 625 2 3 false 0.15580000000000666 0.15580000000000666 2.2359681686760748E-181 growth GO:0040007 12133 646 35 4 10446 34 1 false 0.15597790881830093 0.15597790881830093 0.0 B_cell_activation GO:0042113 12133 160 35 2 403 2 1 false 0.15703122106588324 0.15703122106588324 6.533922499780693E-117 negative_regulation_of_striated_muscle_cell_differentiation GO:0051154 12133 17 35 1 208 2 3 false 0.15714418431809243 0.15714418431809243 2.72756232006883E-25 regulation_of_DNA-dependent_DNA_replication GO:0090329 12133 25 35 1 159 1 2 false 0.15723270440251885 0.15723270440251885 1.0490694573587729E-29 regulation_of_cell_junction_assembly GO:1901888 12133 35 35 1 1245 6 3 false 0.15754966495593692 0.15754966495593692 7.812749785355693E-69 protein_catabolic_process GO:0030163 12133 498 35 5 3569 21 2 false 0.15859402727885563 0.15859402727885563 0.0 negative_regulation_of_phosphorylation GO:0042326 12133 215 35 2 1463 5 3 false 0.15895522160110065 0.15895522160110065 2.1310280163327356E-264 regulation_of_cytokine_production GO:0001817 12133 323 35 3 1562 7 2 false 0.15946809266840584 0.15946809266840584 0.0 chaperone_binding GO:0051087 12133 41 35 1 6397 27 1 false 0.15967094609751586 0.15967094609751586 3.429149968401103E-107 microtubule_organizing_center GO:0005815 12133 413 35 3 1076 4 2 false 0.16064585969505835 0.16064585969505835 2.6476518998275E-310 negative_regulation_of_peptidyl-tyrosine_phosphorylation GO:0050732 12133 30 35 1 357 2 3 false 0.16122179208763232 0.16122179208763232 2.443461883518979E-44 anatomical_structure_morphogenesis GO:0009653 12133 1664 35 8 3447 12 2 false 0.1617838062466932 0.1617838062466932 0.0 DNA_topoisomerase_type_II_(ATP-hydrolyzing)_activity GO:0003918 12133 6 35 1 71 2 2 false 0.16297786720322102 0.16297786720322102 6.9823138478995105E-9 response_to_osmotic_stress GO:0006970 12133 43 35 1 2681 11 2 false 0.16321836463858427 0.16321836463858427 3.246680302266631E-95 regulation_of_transferase_activity GO:0051338 12133 667 35 3 2708 6 2 false 0.16341347328317038 0.16341347328317038 0.0 regulation_of_vasculature_development GO:1901342 12133 141 35 2 1139 6 2 false 0.16350657029337762 0.16350657029337762 1.7255097841170828E-184 coated_pit GO:0005905 12133 52 35 1 10213 35 3 false 0.1638592218429608 0.1638592218429608 3.070128605674566E-141 multicellular_organismal_development GO:0007275 12133 3069 35 12 4373 14 2 false 0.16395088154810544 0.16395088154810544 0.0 negative_regulation_of_systemic_arterial_blood_pressure GO:0003085 12133 11 35 1 67 1 2 false 0.16417910447761364 0.16417910447761364 7.781717560880856E-13 lipid_particle GO:0005811 12133 34 35 1 5117 27 1 false 0.1651148353395503 0.1651148353395503 2.5784478668075694E-88 blood_vessel_morphogenesis GO:0048514 12133 368 35 3 2812 11 3 false 0.1652611520999574 0.1652611520999574 0.0 cell_junction_organization GO:0034330 12133 181 35 2 7663 31 2 false 0.16571187361728434 0.16571187361728434 0.0 negative_regulation_of_developmental_growth GO:0048640 12133 25 35 1 702 5 4 false 0.16626443122287937 0.16626443122287937 1.6596304452821465E-46 signalosome GO:0008180 12133 32 35 1 4399 25 2 false 0.16725332536066134 0.16725332536066134 7.6195658646057E-82 stress-activated_MAPK_cascade GO:0051403 12133 207 35 2 504 2 2 false 0.1682050553820578 0.1682050553820578 1.7060805667457382E-147 negative_regulation_of_signaling GO:0023057 12133 597 35 4 4884 18 3 false 0.16943864097043132 0.16943864097043132 0.0 monovalent_inorganic_cation_homeostasis GO:0055067 12133 56 35 1 330 1 1 false 0.16969696969696543 0.16969696969696543 9.24814230107908E-65 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 35 7 5447 29 3 false 0.17030132969607703 0.17030132969607703 0.0 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 35 4 200 9 3 false 0.1704382094734657 0.1704382094734657 7.491323649368413E-49 viral_infectious_cycle GO:0019058 12133 213 35 8 557 15 1 false 0.17058121785115682 0.17058121785115682 3.455075709157513E-160 regulation_of_sodium_ion_transport GO:0002028 12133 37 35 1 215 1 2 false 0.17209302325580766 0.17209302325580766 1.8499074186131244E-42 perinuclear_region_of_cytoplasm GO:0048471 12133 416 35 4 5117 27 1 false 0.17222709332665254 0.17222709332665254 0.0 cysteine-type_endopeptidase_activity GO:0004197 12133 219 35 2 527 2 2 false 0.17222819460181882 0.17222819460181882 1.229090165658057E-154 positive_regulation_of_endocytosis GO:0045807 12133 63 35 1 1023 3 4 false 0.17376597104948882 0.17376597104948882 3.3235317732048763E-102 respiratory_burst_involved_in_inflammatory_response GO:0002536 12133 4 35 1 23 1 2 false 0.1739130434782608 0.1739130434782608 1.1293054771315566E-4 sodium_ion_transport GO:0006814 12133 95 35 1 545 1 2 false 0.17431192660552194 0.17431192660552194 6.918862196703055E-109 negative_regulation_of_protein_phosphorylation GO:0001933 12133 204 35 2 1311 5 4 false 0.17493696889546767 0.17493696889546767 2.3779440904857207E-245 single-organism_process GO:0044699 12133 8052 35 29 10446 34 1 false 0.17544951313322313 0.17544951313322313 0.0 ribose_phosphate_metabolic_process GO:0019693 12133 1207 35 5 3007 8 3 false 0.17553147508575329 0.17553147508575329 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 35 1 3208 15 2 false 0.1758220862962986 0.1758220862962986 7.591030632914061E-95 nucleoplasm GO:0005654 12133 1443 35 13 2767 20 2 false 0.17653106848915398 0.17653106848915398 0.0 transcription_factor_binding GO:0008134 12133 715 35 5 6397 27 1 false 0.17700904608889198 0.17700904608889198 0.0 binding GO:0005488 12133 8962 35 32 10257 34 1 false 0.17870056869829665 0.17870056869829665 0.0 SH2_domain_binding GO:0042169 12133 31 35 1 486 3 1 false 0.17975785134477879 0.17975785134477879 1.1318841086292139E-49 regulation_of_protein_tyrosine_kinase_activity GO:0061097 12133 46 35 1 717 3 2 false 0.18062026097132317 0.18062026097132317 1.0648720362347023E-73 negative_regulation_of_mitosis GO:0045839 12133 43 35 1 656 3 5 false 0.18430045658035457 0.18430045658035457 1.8426541499010044E-68 molecular_function GO:0003674 12133 10257 35 34 11221 35 1 false 0.18447933289726143 0.18447933289726143 0.0 interleukin-10_production GO:0032613 12133 24 35 1 362 3 1 false 0.1864811782290921 0.1864811782290921 5.275049756229495E-38 carbon-oxygen_lyase_activity GO:0016835 12133 43 35 1 230 1 1 false 0.18695652173911087 0.18695652173911087 1.1165562295399568E-47 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 35 2 2776 8 3 false 0.1871632738477957 0.1871632738477957 0.0 p53_binding GO:0002039 12133 49 35 1 6397 27 1 false 0.18782266043291554 0.18782266043291554 2.351284918255247E-124 cellular_component GO:0005575 12133 10701 35 35 11221 35 1 false 0.18950761071715508 0.18950761071715508 0.0 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 35 2 3020 26 2 false 0.18991430643088264 0.18991430643088264 1.1070924240418437E-179 RNA_biosynthetic_process GO:0032774 12133 2751 35 19 4191 25 3 false 0.1902174559509356 0.1902174559509356 0.0 spongiotrophoblast_differentiation GO:0060708 12133 4 35 1 21 1 2 false 0.19047619047619052 0.19047619047619052 1.6708437761069314E-4 regulation_of_interleukin-10_production GO:0032653 12133 22 35 1 324 3 2 false 0.19073401035978654 0.19073401035978654 1.366148041844953E-34 positive_regulation_of_cell_death GO:0010942 12133 383 35 4 3330 20 3 false 0.19093718529685916 0.19093718529685916 0.0 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 35 1 230 1 4 false 0.1913043478260654 0.1913043478260654 2.6271911283291635E-48 origin_recognition_complex GO:0000808 12133 37 35 1 3160 18 2 false 0.19150344393282798 0.19150344393282798 5.523329685243896E-87 histone_deacetylase_activity_(H3-K9_specific) GO:0032129 12133 13 35 2 29 2 2 false 0.19211822660098626 0.19211822660098626 1.4735371515185923E-8 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 35 4 1393 9 3 false 0.19255565843580139 0.19255565843580139 0.0 RNA_helicase_activity GO:0003724 12133 27 35 1 140 1 1 false 0.19285714285713712 0.19285714285713712 1.8047202528374888E-29 regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060334 12133 22 35 1 114 1 3 false 0.1929824561403555 0.1929824561403555 5.496543393824805E-24 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 35 2 859 4 3 false 0.193462696371892 0.193462696371892 3.480270935062193E-190 protein_deacetylase_activity GO:0033558 12133 28 35 2 63 2 2 false 0.19354838709677497 0.19354838709677497 1.5890462849475085E-18 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 35 7 6622 21 1 false 0.1936256904674412 0.1936256904674412 0.0 cell_cycle_phase GO:0022403 12133 253 35 3 953 6 1 false 0.19406173846378102 0.19406173846378102 1.0384727319913012E-238 response_to_growth_hormone_stimulus GO:0060416 12133 32 35 1 313 2 1 false 0.19431473744569167 0.19431473744569167 1.8848967599686449E-44 negative_regulation_of_osteoblast_differentiation GO:0045668 12133 31 35 1 447 3 3 false 0.19436305184323105 0.19436305184323105 1.6516284138914347E-48 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 35 9 6103 32 3 false 0.19490769730043594 0.19490769730043594 0.0 cytokine_production_involved_in_immune_response GO:0002367 12133 40 35 1 1127 6 3 false 0.19532528715996922 0.19532528715996922 1.3767002074384054E-74 nucleus_organization GO:0006997 12133 62 35 1 2031 7 1 false 0.1953466103204472 0.1953466103204472 6.73570952581451E-120 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 35 1 243 3 2 false 0.19628829474170104 0.19628829474170104 1.7559807727942103E-26 MCM_complex GO:0042555 12133 36 35 1 2976 18 2 false 0.19724174385589768 0.19724174385589768 4.093123828825495E-84 MCM_core_complex GO:0097373 12133 36 35 1 2976 18 1 false 0.19724174385589768 0.19724174385589768 4.093123828825495E-84 response_to_abiotic_stimulus GO:0009628 12133 676 35 4 5200 18 1 false 0.19835401875145087 0.19835401875145087 0.0 RNA_processing GO:0006396 12133 601 35 6 3762 25 2 false 0.19862405905378303 0.19862405905378303 0.0 regulation_of_blood_vessel_endothelial_cell_migration GO:0043535 12133 36 35 2 80 2 2 false 0.19936708860759275 0.19936708860759275 1.3816777818746476E-23 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 35 18 8688 33 3 false 0.19964045314380527 0.19964045314380527 0.0 RNA_ligase_activity GO:0008452 12133 1 35 1 5 1 1 false 0.19999999999999996 0.19999999999999996 0.19999999999999996 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 35 1 953 6 4 false 0.2015696503148544 0.2015696503148544 1.0482452124052062E-64 ATP-dependent_RNA_helicase_activity GO:0004004 12133 20 35 1 99 1 3 false 0.20202020202019816 0.20202020202019816 2.332161908415525E-21 muscle_cell_differentiation GO:0042692 12133 267 35 2 2218 7 2 false 0.20206544299836912 0.20206544299836912 0.0 vasculogenesis GO:0001570 12133 62 35 1 3056 11 4 false 0.20215105738466624 0.20215105738466624 4.885889713794216E-131 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 35 1 217 1 1 false 0.20276497695851403 0.20276497695851403 4.514459380304185E-47 SCF-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031146 12133 16 35 1 220 3 1 false 0.20355775931997488 0.20355775931997488 1.2148210927332739E-24 regulation_of_membrane_potential GO:0042391 12133 216 35 2 478 2 1 false 0.20367885055660395 0.20367885055660395 3.2092050959317294E-142 cellular_response_to_growth_hormone_stimulus GO:0071378 12133 27 35 1 251 2 2 false 0.20395219123504957 0.20395219123504957 7.510871738156894E-37 cell_body GO:0044297 12133 239 35 2 9983 35 1 false 0.2040425642928182 0.2040425642928182 0.0 microtubule_cytoskeleton GO:0015630 12133 734 35 4 1430 5 1 false 0.20411297658391972 0.20411297658391972 0.0 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 35 3 1525 10 1 false 0.20411339807916024 0.20411339807916024 1.2095302863090285E-289 positive_regulation_of_nucleocytoplasmic_transport GO:0046824 12133 75 35 1 367 1 3 false 0.20435967302452718 0.20435967302452718 3.7707577442500014E-80 viral_genome_expression GO:0019080 12133 153 35 6 557 15 2 false 0.20511992822899106 0.20511992822899106 1.6461772406083414E-141 histone_methyltransferase_complex GO:0035097 12133 60 35 1 807 3 2 false 0.20711309525000016 0.20711309525000016 3.052234764972827E-92 placenta_blood_vessel_development GO:0060674 12133 22 35 1 487 5 2 false 0.20714208887532548 0.20714208887532548 1.3621649098068716E-38 negative_regulation_of_muscle_cell_differentiation GO:0051148 12133 33 35 1 584 4 3 false 0.2080702241263003 0.2080702241263003 1.1148204606376211E-54 ribonucleotide_catabolic_process GO:0009261 12133 946 35 5 1294 5 3 false 0.20823142315003673 0.20823142315003673 0.0 negative_regulation_of_viral_reproduction GO:0048525 12133 28 35 1 2903 24 4 false 0.20827348005863278 0.20827348005863278 3.8119989558045655E-68 cytoplasmic_mRNA_processing_body GO:0000932 12133 44 35 1 5117 27 2 false 0.2084547593704615 0.2084547593704615 2.0344134807470182E-109 structure-specific_DNA_binding GO:0043566 12133 179 35 2 2091 10 1 false 0.2085904500312989 0.2085904500312989 1.2928223396172998E-264 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 35 5 5051 16 3 false 0.2091298173785423 0.2091298173785423 0.0 protein_transport GO:0015031 12133 1099 35 7 1627 8 2 false 0.2092372031107332 0.2092372031107332 0.0 mitotic_spindle_organization GO:0007052 12133 37 35 1 648 4 2 false 0.21001217530366648 0.21001217530366648 3.6765869552528886E-61 proteasome_complex GO:0000502 12133 62 35 1 9248 35 2 false 0.21011723413069658 0.21011723413069658 4.919625587422917E-161 methyltransferase_complex GO:0034708 12133 62 35 1 9248 35 2 false 0.21011723413069658 0.21011723413069658 4.919625587422917E-161 response_to_stress GO:0006950 12133 2540 35 11 5200 18 1 false 0.21020583852450198 0.21020583852450198 0.0 regulation_of_mitochondrial_membrane_potential GO:0051881 12133 24 35 1 216 2 1 false 0.2103359173126426 0.2103359173126426 2.19808043697053E-32 endocytosis GO:0006897 12133 411 35 2 895 2 2 false 0.2106032769674332 0.2106032769674332 2.7872223899360555E-267 negative_regulation_of_cell_projection_organization GO:0031345 12133 71 35 1 936 3 3 false 0.21094675572562063 0.21094675572562063 1.4196570412903908E-108 potassium_ion_transport GO:0006813 12133 115 35 1 545 1 2 false 0.21100917431194127 0.21100917431194127 2.5935886393871475E-121 activation_of_innate_immune_response GO:0002218 12133 155 35 3 362 4 2 false 0.21191280677554653 0.21191280677554653 1.0665156090103768E-106 sodium_ion_transmembrane_transporter_activity GO:0015081 12133 67 35 1 316 1 3 false 0.21202531645569045 0.21202531645569045 2.2934303131006308E-70 response_to_hypoxia GO:0001666 12133 200 35 2 2540 11 2 false 0.21270090806004566 0.21270090806004566 2.6634431659671552E-303 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 35 2 362 4 4 false 0.2130854777046441 0.2130854777046441 1.827388630734988E-82 negative_regulation_of_protein_modification_process GO:0031400 12133 328 35 3 2431 12 3 false 0.21323938964643968 0.21323938964643968 0.0 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 35 5 2556 8 1 false 0.21352449601985218 0.21352449601985218 0.0 regulation_of_transporter_activity GO:0032409 12133 88 35 1 2973 8 3 false 0.21389186549950068 0.21389186549950068 1.555650039308817E-171 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 35 7 5032 29 4 false 0.21390229706986363 0.21390229706986363 0.0 nucleotide_catabolic_process GO:0009166 12133 969 35 5 1318 5 2 false 0.2142159753731032 0.2142159753731032 0.0 monocyte_chemotaxis GO:0002548 12133 23 35 1 107 1 1 false 0.21495327102804263 0.21495327102804263 6.985599683738772E-24 innate_immune_response GO:0045087 12133 626 35 5 1268 7 2 false 0.2156862757004147 0.2156862757004147 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 35 21 7470 33 2 false 0.2171430506203284 0.2171430506203284 0.0 response_to_heat GO:0009408 12133 56 35 1 2544 11 2 false 0.21755460937398322 0.21755460937398322 2.557066757112981E-116 DNA_replication_initiation GO:0006270 12133 38 35 1 791 5 2 false 0.21870632757374114 0.21870632757374114 9.550826810910352E-66 plasma_membrane_organization GO:0007009 12133 91 35 1 784 2 1 false 0.21880131362890864 0.21880131362890864 1.286258105643369E-121 positive_regulation_of_ion_transport GO:0043270 12133 86 35 1 1086 3 3 false 0.21943839699604084 0.21943839699604084 6.3756507891276546E-130 JAK-STAT_cascade_involved_in_growth_hormone_signaling_pathway GO:0060397 12133 22 35 1 100 1 2 false 0.22000000000000502 0.22000000000000502 1.3638719008708662E-22 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 35 1 162 1 5 false 0.22222222222221105 0.22222222222221105 7.1760328941400225E-37 positive_regulation_of_cysteine-type_endopeptidase_activity GO:2001056 12133 106 35 2 224 2 3 false 0.22281390134528054 0.22281390134528054 9.593761035739944E-67 ribonucleoprotein_complex_assembly GO:0022618 12133 117 35 2 646 5 3 false 0.22413737449615492 0.22413737449615492 4.631331466925404E-132 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 35 2 1631 7 2 false 0.224572033997212 0.224572033997212 3.3133814045702313E-271 sodium_ion_transmembrane_transport GO:0035725 12133 68 35 1 565 2 2 false 0.22641059436394964 0.22641059436394964 1.2033655972436562E-89 activation_of_immune_response GO:0002253 12133 341 35 3 1618 8 2 false 0.22684789478028267 0.22684789478028267 0.0 protein_K48-linked_ubiquitination GO:0070936 12133 37 35 1 163 1 1 false 0.22699386503067412 0.22699386503067412 1.6289154422281443E-37 negative_regulation_of_immune_response GO:0050777 12133 48 35 1 1512 8 4 false 0.22794239258381996 0.22794239258381996 6.35137019676024E-92 T_cell_mediated_immunity GO:0002456 12133 39 35 1 170 1 2 false 0.22941176470587185 0.22941176470587185 2.3810446188225285E-39 DNA-dependent_ATPase_activity GO:0008094 12133 71 35 2 228 3 1 false 0.2294462717160961 0.2294462717160961 6.772142656773899E-61 developmental_cell_growth GO:0048588 12133 63 35 1 1480 6 3 false 0.23006756614650908 0.23006756614650908 1.4193302339112791E-112 cell_cycle_phase_transition GO:0044770 12133 415 35 4 953 6 1 false 0.23108243460587896 0.23108243460587896 1.4433288987581492E-282 positive_regulation_of_interleukin-12_production GO:0032735 12133 23 35 1 187 2 3 false 0.23144155022711987 0.23144155022711987 5.9266111346036784E-30 regulation_of_DNA_metabolic_process GO:0051052 12133 188 35 2 4316 21 3 false 0.23202544116070245 0.23202544116070245 0.0 positive_regulation_of_adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002824 12133 37 35 1 159 1 3 false 0.23270440251572852 0.23270440251572852 4.612534880563942E-37 regulation_of_anatomical_structure_morphogenesis GO:0022603 12133 528 35 4 2074 10 2 false 0.2345134179147555 0.2345134179147555 0.0 regulation_of_cell_motility GO:2000145 12133 370 35 3 831 4 3 false 0.23463925334197935 0.23463925334197935 3.695619588048616E-247 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 35 1 522 1 3 false 0.23754789272030183 0.23754789272030183 1.2617392241842968E-123 regulation_of_viral_genome_replication GO:0045069 12133 43 35 1 181 1 3 false 0.23756906077349124 0.23756906077349124 1.1493804978494703E-42 cellular_biosynthetic_process GO:0044249 12133 4077 35 21 7290 33 2 false 0.23758467096644703 0.23758467096644703 0.0 somatic_diversification_of_immune_receptors GO:0002200 12133 54 35 1 1618 8 2 false 0.23826213763418377 0.23826213763418377 2.9301103973458922E-102 negative_regulation_of_immune_effector_process GO:0002698 12133 45 35 1 518 3 3 false 0.23905364330890744 0.23905364330890744 6.135357945972138E-66 negative_regulation_of_blood_pressure GO:0045776 12133 28 35 1 117 1 1 false 0.2393162393162351 0.2393162393162351 1.267799191286988E-27 M_phase GO:0000279 12133 22 35 1 253 3 1 false 0.23970783532531656 0.23970783532531656 3.8938574183719536E-32 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 35 2 1097 8 3 false 0.24028746675495055 0.24028746675495055 8.208279871491876E-172 leukocyte_homeostasis GO:0001776 12133 55 35 1 1628 8 2 false 0.24084127386320064 0.24084127386320064 7.300149261907148E-104 proteolysis GO:0006508 12133 732 35 6 3431 20 1 false 0.24105061585679227 0.24105061585679227 0.0 negative_regulation_of_cell_differentiation GO:0045596 12133 381 35 3 3552 16 4 false 0.2420992922993457 0.2420992922993457 0.0 regulation_of_angiogenesis GO:0045765 12133 127 35 2 665 5 3 false 0.24399104073819688 0.24399104073819688 3.739492527906887E-140 regulation_of_cytokine-mediated_signaling_pathway GO:0001959 12133 70 35 1 1785 7 3 false 0.24460820246409856 0.24460820246409856 1.145730192869727E-127 in_utero_embryonic_development GO:0001701 12133 295 35 3 471 3 1 false 0.24476276969939914 0.24476276969939914 1.719393530200133E-134 positive_regulation_of_immune_system_process GO:0002684 12133 540 35 4 3595 17 3 false 0.2448727242239282 0.2448727242239282 0.0 monosaccharide_biosynthetic_process GO:0046364 12133 62 35 1 253 1 2 false 0.24505928853752568 0.24505928853752568 1.1247044052233336E-60 positive_regulation_of_developmental_process GO:0051094 12133 603 35 4 4731 20 3 false 0.24544656962650294 0.24544656962650294 0.0 dynein_complex GO:0030286 12133 27 35 1 110 1 1 false 0.24545454545454212 0.24545454545454212 2.7050159623675944E-26 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 35 2 1376 8 3 false 0.2475810229721364 0.2475810229721364 2.059495184181185E-218 response_to_extracellular_stimulus GO:0009991 12133 260 35 1 1046 1 1 false 0.2485659655832476 0.2485659655832476 6.4524154237794786E-254 positive_regulation_of_cell_division GO:0051781 12133 51 35 1 3061 17 3 false 0.24902462635148778 0.24902462635148778 3.9220691729316426E-112 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 35 3 5157 20 3 false 0.24905067531213043 0.24905067531213043 0.0 regulation_of_collateral_sprouting_in_absence_of_injury GO:0048696 12133 3 35 1 12 1 2 false 0.2499999999999996 0.2499999999999996 0.004545454545454539 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 35 4 3605 22 4 false 0.25202299424870234 0.25202299424870234 0.0 RNA-dependent_ATPase_activity GO:0008186 12133 21 35 1 228 3 1 false 0.2526530206065685 0.2526530206065685 4.020483440001667E-30 pre-replicative_complex GO:0036387 12133 28 35 1 110 1 1 false 0.2545454545454507 0.2545454545454507 9.125355053770069E-27 positive_regulation_of_interferon-gamma_production GO:0032729 12133 27 35 1 198 2 3 false 0.25473004153203865 0.25473004153203865 6.81954388073539E-34 response_to_peptide_hormone_stimulus GO:0043434 12133 313 35 2 619 2 2 false 0.2552817729818599 0.2552817729818599 1.4916788604957572E-185 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 35 7 3631 25 4 false 0.2567138204877898 0.2567138204877898 0.0 positive_regulation_of_molecular_function GO:0044093 12133 1303 35 6 10257 34 2 false 0.25803643428874656 0.25803643428874656 0.0 regulation_of_transmembrane_transporter_activity GO:0022898 12133 78 35 1 563 2 3 false 0.2581050928237849 0.2581050928237849 8.813007984613145E-98 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_linear_amides GO:0016811 12133 42 35 2 82 2 1 false 0.25925925925925236 0.25925925925925236 2.4115523257823617E-24 establishment_of_localization_in_cell GO:0051649 12133 1633 35 7 2978 10 2 false 0.2621869429310231 0.2621869429310231 0.0 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 35 4 982 4 1 false 0.2635080284179177 0.2635080284179177 2.6984349291053464E-253 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 35 1 1199 10 2 false 0.26362667487014146 0.26362667487014146 9.194442294553035E-70 ameboidal_cell_migration GO:0001667 12133 185 35 2 734 4 1 false 0.2648893659172867 0.2648893659172867 3.1688746703355204E-179 regulation_of_neuron_projection_development GO:0010975 12133 182 35 1 686 1 3 false 0.26530612244904067 0.26530612244904067 1.2648422067158072E-171 regulation_of_cell_migration GO:0030334 12133 351 35 3 749 4 2 false 0.26641549046400825 0.26641549046400825 5.057884988188172E-224 dendrite GO:0030425 12133 276 35 2 534 2 1 false 0.26666947741225655 0.26666947741225655 6.975042602902724E-160 cell-substrate_adhesion GO:0031589 12133 190 35 1 712 1 1 false 0.26685393258430357 0.26685393258430357 1.237947563614388E-178 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 35 5 1319 5 1 false 0.26790006523726034 0.26790006523726034 6.536050345296563E-309 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 35 20 6638 32 2 false 0.26856104276946535 0.26856104276946535 0.0 positive_regulation_of_lymphocyte_mediated_immunity GO:0002708 12133 38 35 1 141 1 3 false 0.26950354609929694 0.26950354609929694 2.7286874497692006E-35 regulation_of_localization GO:0032879 12133 1242 35 6 7621 27 2 false 0.26997158828178647 0.26997158828178647 0.0 single-organism_cellular_process GO:0044763 12133 7541 35 28 9888 34 2 false 0.27053469722816287 0.27053469722816287 0.0 cell_junction_assembly GO:0034329 12133 159 35 2 1406 9 2 false 0.27063287243148715 0.27063287243148715 9.423437086545545E-215 mitotic_spindle_checkpoint GO:0071174 12133 38 35 1 140 1 2 false 0.27142857142856236 0.27142857142856236 3.73538767395573E-35 organelle_assembly GO:0070925 12133 210 35 2 2677 13 2 false 0.2715718639378155 0.2715718639378155 7.5039E-319 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 35 1 591 4 3 false 0.27212674677647325 0.27212674677647325 1.267222544612779E-68 cellular_process GO:0009987 12133 9675 35 33 10446 34 1 false 0.2731267779961162 0.2731267779961162 0.0 negative_regulation_of_developmental_process GO:0051093 12133 463 35 3 4566 18 3 false 0.27313085263449094 0.27313085263449094 0.0 pore_complex GO:0046930 12133 84 35 1 5051 19 3 false 0.2732755458728679 0.2732755458728679 5.4712090537168384E-185 regulation_of_interleukin-2_production GO:0032663 12133 33 35 1 327 3 2 false 0.2739791575565316 0.2739791575565316 4.834102143986747E-46 membrane_invagination GO:0010324 12133 411 35 2 784 2 1 false 0.27450347955270393 0.27450347955270393 8.658368437912315E-235 positive_regulation_of_protein_import_into_nucleus GO:0042307 12133 61 35 1 222 1 4 false 0.27477477477476364 0.27477477477476364 3.438523611225612E-56 inflammatory_response GO:0006954 12133 381 35 3 1437 7 2 false 0.2753071396482133 0.2753071396482133 0.0 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 35 20 4989 28 5 false 0.2757460239932827 0.2757460239932827 0.0 neuronal_cell_body GO:0043025 12133 215 35 2 621 3 2 false 0.2762599496540926 0.2762599496540926 3.1563152846547707E-173 hexose_biosynthetic_process GO:0019319 12133 57 35 1 206 1 2 false 0.2766990291262256 0.2766990291262256 2.7565278967151444E-52 positive_regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001244 12133 23 35 1 154 2 3 false 0.2772260419318926 0.2772260419318926 7.088148088578188E-28 establishment_of_protein_localization_to_membrane GO:0090150 12133 47 35 1 1185 8 2 false 0.2772873749292997 0.2772873749292997 2.2354784130583705E-85 anatomical_structure_development GO:0048856 12133 3099 35 12 3447 12 1 false 0.2782451061255065 0.2782451061255065 0.0 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 35 4 3910 22 3 false 0.27835593274724957 0.27835593274724957 0.0 blood_vessel_endothelial_cell_migration GO:0043534 12133 53 35 2 100 2 1 false 0.2783838383838401 0.2783838383838401 1.1846448146925151E-29 regulation_of_ion_transmembrane_transporter_activity GO:0032412 12133 73 35 1 485 2 3 false 0.27864019766548853 0.27864019766548853 1.1784649326580688E-88 localization_of_cell GO:0051674 12133 785 35 4 3467 12 1 false 0.2795323231985773 0.2795323231985773 0.0 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 35 1 1672 8 5 false 0.2795471292231777 0.2795471292231777 1.5388096674355026E-121 immune_response GO:0006955 12133 1006 35 5 5335 19 2 false 0.28049465379304334 0.28049465379304334 0.0 macrophage_activation GO:0042116 12133 29 35 1 103 1 1 false 0.28155339805824753 0.28155339805824753 2.953431182822629E-26 positive_regulation_of_interleukin-6_production GO:0032755 12133 30 35 1 197 2 3 false 0.2820366725370142 0.2820366725370142 3.985261139015803E-36 coated_vesicle GO:0030135 12133 202 35 1 712 1 1 false 0.28370786516858804 0.28370786516858804 1.1363731817938802E-183 secretory_granule GO:0030141 12133 202 35 1 712 1 1 false 0.28370786516858804 0.28370786516858804 1.1363731817938802E-183 single-organism_carbohydrate_catabolic_process GO:0044724 12133 110 35 1 386 1 2 false 0.2849740932642283 0.2849740932642283 1.4747416896601825E-99 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 35 1 856 1 3 false 0.285046728972063 0.285046728972063 2.175375701359491E-221 cellular_response_to_type_I_interferon GO:0071357 12133 59 35 1 382 2 2 false 0.28538841021833766 0.28538841021833766 7.131731716015008E-71 regulation_of_response_to_cytokine_stimulus GO:0060759 12133 76 35 1 2275 10 2 false 0.28855628914248144 0.28855628914248144 4.9547358949088833E-144 SCF_ubiquitin_ligase_complex GO:0019005 12133 26 35 1 90 1 1 false 0.2888888888888934 0.2888888888888934 3.4442933577123775E-23 negative_regulation_of_viral_genome_replication GO:0045071 12133 27 35 1 93 1 4 false 0.2903225806451571 0.2903225806451571 5.123998834104114E-24 interleukin-2_production GO:0032623 12133 39 35 1 362 3 1 false 0.29034845400795734 0.29034845400795734 2.768478137430898E-53 purine_nucleotide_catabolic_process GO:0006195 12133 956 35 5 1223 5 3 false 0.29118072592024585 0.29118072592024585 6.80299167777575E-278 cellular_potassium_ion_transport GO:0071804 12133 92 35 1 7541 28 2 false 0.2912984030191263 0.2912984030191263 4.105440908779901E-215 regulation_of_cell_death GO:0010941 12133 1062 35 5 6437 22 2 false 0.2917703473232416 0.2917703473232416 0.0 gluconeogenesis GO:0006094 12133 54 35 1 185 1 2 false 0.2918918918919016 0.2918918918919016 4.74373526943691E-48 negative_regulation_of_catalytic_activity GO:0043086 12133 588 35 3 4970 16 3 false 0.29201867177462887 0.29201867177462887 0.0 potassium_ion_transmembrane_transporter_activity GO:0015079 12133 92 35 1 315 1 3 false 0.2920634920635222 0.2920634920635222 4.7759735730125735E-82 negative_regulation_of_gene_expression GO:0010629 12133 817 35 7 3906 26 3 false 0.2921524548775352 0.2921524548775352 0.0 biological_process GO:0008150 12133 10446 35 34 11221 35 1 false 0.2933319063240497 0.2933319063240497 0.0 apoptotic_signaling_pathway GO:0097190 12133 305 35 2 3954 14 2 false 0.2946311333808362 0.2946311333808362 0.0 regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001242 12133 31 35 1 193 2 2 false 0.29614637305698555 0.29614637305698555 1.4758328099403201E-36 peptidase_activity GO:0008233 12133 614 35 3 2556 8 1 false 0.29710662265475063 0.29710662265475063 0.0 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 35 1 222 2 3 false 0.29864253393661766 0.29864253393661766 2.5456303013282065E-42 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 35 2 3568 14 3 false 0.2988055680347357 0.2988055680347357 0.0 cellular_component_biogenesis GO:0044085 12133 1525 35 10 3839 21 1 false 0.2988926268906832 0.2988926268906832 0.0 NAD-dependent_histone_deacetylase_activity GO:0017136 12133 15 35 2 27 2 2 false 0.29914529914529997 0.29914529914529997 5.75246234150529E-8 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 35 5 2807 8 3 false 0.2993820805556989 0.2993820805556989 0.0 regulation_of_T_cell_mediated_immunity GO:0002709 12133 27 35 1 90 1 3 false 0.30000000000000426 0.30000000000000426 1.453061260284883E-23 regulation_of_mitosis GO:0007088 12133 100 35 1 611 2 4 false 0.3007700356847076 0.3007700356847076 1.2375244614825155E-117 cellular_response_to_organic_nitrogen GO:0071417 12133 323 35 2 1478 5 4 false 0.3009778065381845 0.3009778065381845 0.0 regulation_of_phagocytosis GO:0050764 12133 36 35 1 220 2 2 false 0.3011207970111959 0.3011207970111959 3.6295761070555344E-42 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 35 5 1202 5 3 false 0.3012678668913705 0.3012678668913705 1.616697592155103E-269 regulation_of_metal_ion_transport GO:0010959 12133 159 35 1 527 1 2 false 0.30170777988610137 0.30170777988610137 1.9143009234930405E-139 regulation_of_endopeptidase_activity GO:0052548 12133 264 35 2 480 2 2 false 0.3019832985387032 0.3019832985387032 9.691263405564588E-143 chromatin_binding GO:0003682 12133 309 35 2 8962 32 1 false 0.302868875569592 0.302868875569592 0.0 positive_regulation_of_adaptive_immune_response GO:0002821 12133 40 35 1 465 4 3 false 0.3030306098401971 0.3030306098401971 9.195425616310837E-59 negative_regulation_of_response_to_external_stimulus GO:0032102 12133 105 35 1 1508 5 3 false 0.303268143359365 0.303268143359365 8.164414473234676E-165 interleukin-12_production GO:0032615 12133 41 35 1 362 3 1 false 0.3034898965937738 0.3034898965937738 4.36542521141724E-55 potassium_ion_transmembrane_transport GO:0071805 12133 92 35 1 556 2 2 false 0.30380452394842916 0.30380452394842916 1.0312185181817459E-107 organic_substance_transport GO:0071702 12133 1580 35 7 2783 10 1 false 0.3046232496745263 0.3046232496745263 0.0 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 35 1 206 1 2 false 0.3058252427184593 0.3058252427184593 1.364605297408496E-54 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 35 2 220 3 1 false 0.3060084316839271 0.3060084316839271 2.4407604211478482E-62 DNA_helicase_activity GO:0003678 12133 45 35 1 147 1 2 false 0.30612244897958646 0.30612244897958646 6.658599492091069E-39 positive_regulation_of_response_to_external_stimulus GO:0032103 12133 126 35 1 1783 5 3 false 0.307100440821628 0.307100440821628 4.953245093659787E-197 negative_regulation_of_multi-organism_process GO:0043901 12133 51 35 1 3360 24 3 false 0.30812549348389046 0.30812549348389046 3.258164733926273E-114 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 35 7 4597 16 2 false 0.30832258723793493 0.30832258723793493 0.0 regulation_of_protein_modification_process GO:0031399 12133 1001 35 6 2566 12 2 false 0.3085576163715722 0.3085576163715722 0.0 regulation_of_skeletal_muscle_fiber_development GO:0048742 12133 44 35 1 499 4 4 false 0.30954411957755196 0.30954411957755196 3.601904577093225E-64 immune_system_development GO:0002520 12133 521 35 3 3460 13 2 false 0.31012691900813516 0.31012691900813516 0.0 positive_regulation_of_proteolysis GO:0045862 12133 69 35 1 1334 7 3 false 0.31108013077550156 0.31108013077550156 2.369917275782091E-117 microtubule_cytoskeleton_organization GO:0000226 12133 259 35 1 831 1 2 false 0.31167268351379257 0.31167268351379257 4.0880234187670296E-223 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 35 2 442 2 3 false 0.3117246898760163 0.3117246898760163 4.945935388068452E-131 passive_transmembrane_transporter_activity GO:0022803 12133 304 35 2 544 2 1 false 0.3118297042574906 0.3118297042574906 2.1953421087848878E-161 regulation_of_DNA_recombination GO:0000018 12133 38 35 1 324 3 2 false 0.31304889105398015 0.31304889105398015 1.9894741609704344E-50 regulation_of_response_to_interferon-gamma GO:0060330 12133 23 35 1 319 5 3 false 0.31382194021433185 0.31382194021433185 1.507111625705858E-35 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 35 1 722 2 3 false 0.3164848759611147 0.3164848759611147 8.18717732691146E-144 receptor_signaling_protein_activity GO:0005057 12133 339 35 1 1070 1 1 false 0.3168224299066703 0.3168224299066703 2.5248591221043436E-289 NAD-dependent_protein_deacetylase_activity GO:0034979 12133 16 35 2 28 2 1 false 0.3174603174603193 0.3174603174603193 3.287121338003005E-8 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 35 2 308 2 2 false 0.31835103007736393 0.31835103007736393 5.66231040699253E-91 cellular_component_movement GO:0006928 12133 1012 35 5 7541 28 1 false 0.31990791920692385 0.31990791920692385 0.0 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 35 2 1256 12 1 false 0.32052598157666023 0.32052598157666023 3.1457660386089413E-171 magnesium_ion_binding GO:0000287 12133 145 35 1 2699 7 1 false 0.320899738927589 0.320899738927589 1.2358584675012654E-244 immunoglobulin_production_involved_in_immunoglobulin_mediated_immune_response GO:0002381 12133 37 35 1 115 1 2 false 0.3217391304347844 0.3217391304347844 5.328533934457324E-31 positive_regulation_of_cytokine_production GO:0001819 12133 175 35 2 614 4 3 false 0.32177011693305135 0.32177011693305135 1.2195240299259301E-158 substrate-specific_channel_activity GO:0022838 12133 291 35 2 512 2 2 false 0.3225522871820936 0.3225522871820936 2.547694139879492E-151 establishment_or_maintenance_of_cell_polarity GO:0007163 12133 104 35 1 7541 28 1 false 0.3226356035875514 0.3226356035875514 1.175072893510937E-237 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 35 2 5033 19 3 false 0.3228762703454532 0.3228762703454532 0.0 positive_regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032436 12133 35 35 1 288 3 4 false 0.32305347091929176 0.32305347091929176 7.428075320192054E-46 regulation_of_endothelial_cell_migration GO:0010594 12133 69 35 2 121 2 2 false 0.3231404958677782 0.3231404958677782 1.7052033231209872E-35 cellular_response_to_stress GO:0033554 12133 1124 35 5 4743 16 2 false 0.32325364303877624 0.32325364303877624 0.0 isotype_switching_to_IgG_isotypes GO:0048291 12133 11 35 1 34 1 1 false 0.32352941176470384 0.32352941176470384 3.4953087364262726E-9 negative_regulation_of_transport GO:0051051 12133 243 35 2 4618 22 3 false 0.3235999056252785 0.3235999056252785 0.0 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 35 1 1198 6 4 false 0.3257099804954392 0.3257099804954392 2.335035261625238E-122 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 35 1 450 1 2 false 0.3266666666666245 0.3266666666666245 8.40005869125793E-123 regulation_of_interleukin-12_production GO:0032655 12133 40 35 1 324 3 2 false 0.3274098858968682 0.3274098858968682 3.8076060497039656E-52 regulation_of_protein_kinase_B_signaling_cascade GO:0051896 12133 80 35 1 646 3 2 false 0.32785049520844767 0.32785049520844767 1.7925842553941532E-104 ion_transmembrane_transport GO:0034220 12133 556 35 2 970 2 2 false 0.32830104369452756 0.32830104369452756 1.3121997139332702E-286 regulation_of_blood_pressure GO:0008217 12133 117 35 1 2120 7 2 false 0.32831786068109914 0.32831786068109914 6.820682324461924E-196 regulation_of_response_to_biotic_stimulus GO:0002831 12133 80 35 1 2255 11 2 false 0.32849535864377594 0.32849535864377594 1.6552927666708391E-149 sodium_channel_regulator_activity GO:0017080 12133 14 35 1 78 2 2 false 0.3286713286713216 0.3286713286713216 9.768201397951623E-16 lymphocyte_activation_involved_in_immune_response GO:0002285 12133 78 35 1 432 2 2 false 0.3288540861047143 0.3288540861047143 5.057484756456232E-88 regulation_of_neuron_differentiation GO:0045664 12133 281 35 1 853 1 2 false 0.32942555685824965 0.32942555685824965 5.679328733626827E-234 small_conjugating_protein_ligase_binding GO:0044389 12133 147 35 2 1005 8 1 false 0.3310252924245495 0.3310252924245495 6.302468729220369E-181 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 35 1 242 2 2 false 0.3311957751791627 0.3311957751791627 2.220259827778367E-49 positive_regulation_of_proteasomal_protein_catabolic_process GO:1901800 12133 36 35 1 287 3 4 false 0.3320863988386028 0.3320863988386028 1.2079535246838254E-46 regulation_of_muscle_organ_development GO:0048634 12133 106 35 1 1105 4 2 false 0.3323296847016261 0.3323296847016261 5.2870889259577626E-151 isomerase_activity GO:0016853 12133 123 35 1 4901 16 1 false 0.3345602199945619 0.3345602199945619 7.077862449152851E-249 leukocyte_proliferation GO:0070661 12133 167 35 1 1316 3 1 false 0.3346528095621582 0.3346528095621582 1.1010684152010674E-216 regulation_of_protein_stability GO:0031647 12133 99 35 1 2240 9 2 false 0.33473563730460976 0.33473563730460976 1.7785498552391114E-175 regulation_of_viral_reproduction GO:0050792 12133 101 35 1 6451 26 3 false 0.33707433345115684 0.33707433345115684 3.49743359338843E-225 type_I_interferon-mediated_signaling_pathway GO:0060337 12133 59 35 1 318 2 2 false 0.3371227903100752 0.3371227903100752 9.855417365479732E-66 protein_localization GO:0008104 12133 1434 35 8 1642 8 1 false 0.3375439059873846 0.3375439059873846 3.426309620265761E-270 protein_domain_specific_binding GO:0019904 12133 486 35 3 6397 27 1 false 0.3376056116637467 0.3376056116637467 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 35 2 6813 25 2 false 0.33781468399592485 0.33781468399592485 0.0 regulation_of_cell_development GO:0060284 12133 446 35 3 1519 7 2 false 0.33831088765489714 0.33831088765489714 0.0 cellular_component_assembly GO:0022607 12133 1392 35 9 3836 21 2 false 0.33852697983611446 0.33852697983611446 0.0 response_to_type_I_interferon GO:0034340 12133 60 35 1 900 6 2 false 0.3397605800186384 0.3397605800186384 3.4610416117449214E-95 osteoblast_differentiation GO:0001649 12133 126 35 1 2191 7 2 false 0.3397791383428188 0.3397791383428188 1.111366645898294E-208 negative_regulation_of_inflammatory_response GO:0050728 12133 56 35 1 432 3 4 false 0.3413400720636717 0.3413400720636717 7.653768457766755E-72 protein_folding GO:0006457 12133 183 35 2 3038 20 1 false 0.34149672624079896 0.34149672624079896 1.582632936584301E-299 protein_monoubiquitination GO:0006513 12133 37 35 1 548 6 1 false 0.343892068363745 0.343892068363745 2.2069453336747442E-58 positive_regulation_of_T_cell_mediated_immunity GO:0002711 12133 21 35 1 61 1 4 false 0.34426229508197104 0.34426229508197104 8.212668542575557E-17 PDZ_domain_binding GO:0030165 12133 64 35 1 486 3 1 false 0.34593566614795124 0.34593566614795124 1.107236943980768E-81 intracellular_organelle GO:0043229 12133 7958 35 32 9096 35 2 false 0.34645917525521785 0.34645917525521785 0.0 DNA_recombination GO:0006310 12133 190 35 2 791 5 1 false 0.346474535249834 0.346474535249834 1.2250789605162758E-188 RNA_stabilization GO:0043489 12133 22 35 2 37 2 1 false 0.3468468468468479 0.3468468468468479 1.0678969112465738E-10 regulation_of_embryonic_development GO:0045995 12133 73 35 1 1410 8 2 false 0.34713144796136636 0.34713144796136636 3.810799800640736E-124 organelle_outer_membrane GO:0031968 12133 110 35 1 9084 35 4 false 0.3476760649709235 0.3476760649709235 1.1973077012984011E-257 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 35 1 6380 20 3 false 0.348438949898517 0.348438949898517 2.5067679665083333E-283 cysteine-type_endopeptidase_activator_activity_involved_in_apoptotic_process GO:0008656 12133 20 35 1 104 2 3 false 0.3491411501120088 0.3491411501120088 7.829117748316494E-22 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 35 2 389 5 3 false 0.34947476412338885 0.34947476412338885 8.074632425282073E-93 cellular_localization GO:0051641 12133 1845 35 8 7707 28 2 false 0.3495436186411329 0.3495436186411329 0.0 protein_complex_biogenesis GO:0070271 12133 746 35 6 1525 10 1 false 0.3501581797769502 0.3501581797769502 0.0 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 35 1 2735 15 4 false 0.352824405610372 0.352824405610372 2.836340851870023E-153 regulation_of_extent_of_cell_growth GO:0061387 12133 36 35 1 266 3 2 false 0.3546924773340023 0.3546924773340023 2.2514786516953428E-45 glucose_catabolic_process GO:0006007 12133 68 35 1 191 1 2 false 0.3560209424083976 0.3560209424083976 1.6292167386385306E-53 DNA_conformation_change GO:0071103 12133 194 35 2 791 5 1 false 0.3571621324642271 0.3571621324642271 1.3022788504353465E-190 connective_tissue_development GO:0061448 12133 156 35 1 1132 3 1 false 0.35934249955024117 0.35934249955024117 2.187737558502385E-196 interferon-gamma-mediated_signaling_pathway GO:0060333 12133 66 35 1 330 2 2 false 0.36048632218842164 0.36048632218842164 3.5052495329479947E-71 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 35 2 2943 15 3 false 0.36075796098452984 0.36075796098452984 0.0 positive_regulation_of_leukocyte_mediated_immunity GO:0002705 12133 40 35 1 200 2 3 false 0.3608040201004688 0.3608040201004688 4.877672854200545E-43 regulation_of_type_I_interferon-mediated_signaling_pathway GO:0060338 12133 24 35 1 282 5 3 false 0.3611421539379477 0.3611421539379477 2.655253961660049E-35 erythrocyte_differentiation GO:0030218 12133 88 35 1 243 1 2 false 0.3621399176954674 0.3621399176954674 1.540826297870933E-68 embryonic_placenta_development GO:0001892 12133 68 35 1 489 3 3 false 0.3624888765345962 0.3624888765345962 4.4127719336252255E-85 neuron_part GO:0097458 12133 612 35 3 9983 35 1 false 0.36389634928962766 0.36389634928962766 0.0 ion_channel_activity GO:0005216 12133 286 35 2 473 2 2 false 0.3650965707528729 0.3650965707528729 3.7303800171637374E-137 monosaccharide_catabolic_process GO:0046365 12133 82 35 1 224 1 2 false 0.36607142857142033 0.36607142857142033 2.289161155703443E-63 early_endosome GO:0005769 12133 167 35 1 455 1 1 false 0.36703296703298155 0.36703296703298155 3.2726776377044107E-129 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 35 1 286 1 3 false 0.36713286713287985 0.36713286713287985 4.516187028693684E-81 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 35 1 415 4 1 false 0.36926596345186424 0.36926596345186424 2.1919403735850567E-61 negative_regulation_of_reproductive_process GO:2000242 12133 65 35 1 3420 24 3 false 0.3700416207607017 0.3700416207607017 2.9542142879788904E-139 regulation_of_immune_effector_process GO:0002697 12133 188 35 2 891 6 2 false 0.3717295047407851 0.3717295047407851 1.2449327492079068E-198 developmental_growth_involved_in_morphogenesis GO:0060560 12133 96 35 1 1700 8 2 false 0.3724994302887183 0.3724994302887183 1.149882165195891E-159 hexose_catabolic_process GO:0019320 12133 78 35 1 209 1 2 false 0.3732057416268218 0.3732057416268218 1.9037581511122798E-59 cellular_response_to_hormone_stimulus GO:0032870 12133 384 35 2 1510 5 3 false 0.3762788982078102 0.3762788982078102 0.0 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 35 1 2191 9 3 false 0.37694905351796826 0.37694905351796826 2.495063769189982E-191 response_to_oxygen_levels GO:0070482 12133 214 35 2 676 4 1 false 0.3775548950177129 0.3775548950177129 1.6255941364061853E-182 protein_transporter_activity GO:0008565 12133 81 35 1 1579 9 2 false 0.37822999221456594 0.37822999221456594 3.989743647530564E-138 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 35 5 5778 21 3 false 0.3786052281817952 0.3786052281817952 0.0 cellular_response_to_interferon-gamma GO:0071346 12133 83 35 1 392 2 2 false 0.37906466934595223 0.37906466934595223 2.629901965674187E-87 interferon-alpha_production GO:0032607 12133 15 35 1 71 2 1 false 0.38028169014085 0.38028169014085 1.0932134464693268E-15 production_of_molecular_mediator_of_immune_response GO:0002440 12133 94 35 1 1618 8 1 false 0.38114834740473724 0.38114834740473724 3.880703619863946E-155 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 35 3 1730 6 2 false 0.38396438686140016 0.38396438686140016 0.0 immune_effector_process GO:0002252 12133 445 35 3 1618 8 1 false 0.3845565680531331 0.3845565680531331 0.0 collateral_sprouting_in_absence_of_injury GO:0048669 12133 5 35 1 13 1 1 false 0.3846153846153848 0.3846153846153848 7.770007770007754E-4 myeloid_leukocyte_activation GO:0002274 12133 103 35 1 475 2 1 false 0.3870219853431466 0.3870219853431466 3.072903248484832E-107 cell_motility GO:0048870 12133 785 35 4 1249 5 3 false 0.3875476696858574 0.3875476696858574 0.0 negative_regulation_of_defense_response GO:0031348 12133 72 35 1 1505 10 3 false 0.38843640170645904 0.38843640170645904 5.674310231559274E-125 negative_regulation_of_cell_development GO:0010721 12133 106 35 1 1346 6 3 false 0.3892761999236762 0.3892761999236762 1.6785551446261856E-160 phosphorylation GO:0016310 12133 1421 35 5 2776 8 1 false 0.389411395687939 0.389411395687939 0.0 peptidase_regulator_activity GO:0061134 12133 142 35 1 1218 4 3 false 0.39133683564010024 0.39133683564010024 9.663336317212262E-190 envelope GO:0031975 12133 641 35 3 9983 35 1 false 0.3921721473558345 0.3921721473558345 0.0 response_to_topologically_incorrect_protein GO:0035966 12133 133 35 1 3273 12 2 false 0.3926600029399677 0.3926600029399677 7.334457285081863E-241 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 35 3 1779 3 1 false 0.39358438395006545 0.39358438395006545 0.0 regulation_of_cell_size GO:0008361 12133 62 35 1 157 1 1 false 0.3949044585987098 0.3949044585987098 2.7714927335108436E-45 B_cell_activation_involved_in_immune_response GO:0002312 12133 42 35 1 189 2 2 false 0.3959810874703952 0.3959810874703952 4.7631707498717995E-43 nuclear_pore GO:0005643 12133 69 35 1 2781 20 3 false 0.3960299241622532 0.3960299241622532 8.971129873692015E-140 spindle_checkpoint GO:0031577 12133 45 35 1 202 2 1 false 0.3967784838184953 0.3967784838184953 4.3818533729449334E-46 regulation_of_protein_metabolic_process GO:0051246 12133 1388 35 8 5563 28 3 false 0.3977640762904825 0.3977640762904825 0.0 JAK-STAT_cascade GO:0007259 12133 96 35 1 806 4 1 false 0.39847353541830316 0.39847353541830316 3.5358394194592134E-127 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 35 1 750 1 3 false 0.39866666666682765 0.39866666666682765 3.090255244762607E-218 regulation_of_lymphocyte_mediated_immunity GO:0002706 12133 63 35 1 158 1 2 false 0.39873417721520893 0.39873417721520893 1.105088874754345E-45 chromosome_segregation GO:0007059 12133 136 35 1 7541 28 1 false 0.3998074263189064 0.3998074263189064 5.819868354628029E-295 B_cell_proliferation GO:0042100 12133 56 35 1 249 2 2 false 0.39992226972409434 0.39992226972409434 3.7670734683867574E-57 histone_deacetylase_binding GO:0042826 12133 62 35 1 1005 8 1 false 0.40025669758496374 0.40025669758496374 1.577479125629217E-100 regulation_of_interferon-alpha_production GO:0032647 12133 15 35 1 67 2 2 false 0.40027137042063277 0.40027137042063277 2.892004811076329E-15 ATP-dependent_DNA_helicase_activity GO:0004003 12133 32 35 1 142 2 3 false 0.4011587254020473 0.4011587254020473 1.5505006270676482E-32 regulation_of_DNA_replication GO:0006275 12133 92 35 1 2913 16 3 false 0.4023924795282467 0.4023924795282467 1.0142928746758388E-176 microtubule-based_movement GO:0007018 12133 120 35 1 1228 5 2 false 0.40252057629170473 0.40252057629170473 5.405870557000572E-170 negative_regulation_of_ligase_activity GO:0051352 12133 71 35 1 1003 7 3 false 0.402814804157603 0.402814804157603 8.698138776450475E-111 regulation_of_developmental_growth GO:0048638 12133 94 35 1 1506 8 3 false 0.4035989382386499 0.4035989382386499 4.057398903134269E-152 protein_kinase_B_signaling_cascade GO:0043491 12133 98 35 1 806 4 1 false 0.4052369589855971 0.4052369589855971 6.677067387386742E-129 response_to_endoplasmic_reticulum_stress GO:0034976 12133 111 35 1 1124 5 1 false 0.4059936416178164 0.4059936416178164 1.1256089410717349E-156 motor_activity GO:0003774 12133 106 35 1 1059 5 1 false 0.4104411124142795 0.4104411124142795 6.057882372955599E-149 single-organism_developmental_process GO:0044767 12133 2776 35 11 8064 29 2 false 0.41238704692513245 0.41238704692513245 0.0 DNA_catabolic_process GO:0006308 12133 66 35 1 2145 17 3 false 0.41334395757017023 0.41334395757017023 1.9973602853494904E-127 purine_nucleoside_metabolic_process GO:0042278 12133 1054 35 5 1257 5 2 false 0.4138657493358263 0.4138657493358263 1.399683863089717E-240 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 35 2 1398 5 2 false 0.41470074881286517 0.41470074881286517 0.0 response_to_stimulus GO:0050896 12133 5200 35 18 10446 34 1 false 0.4218115843180845 0.4218115843180845 0.0 circulatory_system_process GO:0003013 12133 307 35 1 1272 2 1 false 0.42459757829495026 0.42459757829495026 1.974873217376429E-304 regulation_of_GTPase_activity GO:0043087 12133 277 35 1 1145 2 3 false 0.4254771429444244 0.4254771429444244 2.6919247726004267E-274 cellular_response_to_nitrogen_compound GO:1901699 12133 347 35 2 1721 7 2 false 0.42792444304677074 0.42792444304677074 0.0 regulation_of_adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002822 12133 70 35 1 163 1 2 false 0.42944785276073405 0.42944785276073405 6.913027082032024E-48 leukocyte_chemotaxis GO:0030595 12133 107 35 1 249 1 2 false 0.4297188755020236 0.4297188755020236 2.556499812614757E-73 ubiquitin_ligase_complex GO:0000151 12133 147 35 1 9248 35 2 false 0.42984516245863136 0.42984516245863136 0.0 insulin_receptor_signaling_pathway GO:0008286 12133 151 35 1 617 2 2 false 0.42987118230232807 0.42987118230232807 2.0667953594506098E-148 regulation_of_transmembrane_transport GO:0034762 12133 183 35 1 6614 20 3 false 0.42992675869390584 0.42992675869390584 0.0 protein_oligomerization GO:0051259 12133 288 35 3 743 6 1 false 0.42993082709248054 0.42993082709248054 1.196705520432063E-214 morphogenesis_of_a_branching_structure GO:0001763 12133 169 35 1 4284 14 3 false 0.43127070826010266 0.43127070826010266 2.023740855196032E-308 muscle_cell_development GO:0055001 12133 141 35 1 1322 5 2 false 0.4315411220037144 0.4315411220037144 3.535972780015326E-194 interferon-gamma_production GO:0032609 12133 62 35 1 362 3 1 false 0.4318141238528127 0.4318141238528127 1.850355343046636E-71 interleukin-6_production GO:0032635 12133 62 35 1 362 3 1 false 0.4318141238528127 0.4318141238528127 1.850355343046636E-71 regulation_of_interferon-gamma_production GO:0032649 12133 56 35 1 327 3 2 false 0.4318845222992602 0.4318845222992602 1.6186616272743486E-64 proteasomal_protein_catabolic_process GO:0010498 12133 231 35 3 498 5 2 false 0.432193229634281 0.432193229634281 1.2543475178088858E-148 myeloid_cell_homeostasis GO:0002262 12133 111 35 1 1628 8 2 false 0.4323231925661267 0.4323231925661267 2.626378318706563E-175 regulation_of_translation GO:0006417 12133 210 35 2 3605 25 4 false 0.4325656688539514 0.4325656688539514 0.0 positive_regulation_of_inflammatory_response GO:0050729 12133 58 35 1 543 5 4 false 0.4327853498629497 0.4327853498629497 1.3309637222630526E-79 negative_regulation_of_Wnt_receptor_signaling_pathway GO:0030178 12133 93 35 1 705 4 3 false 0.4328661795765271 0.4328661795765271 8.718998498418959E-119 regulation_of_muscle_tissue_development GO:1901861 12133 105 35 1 1351 7 2 false 0.43315011101908496 0.43315011101908496 1.3105194568745759E-159 regulation_of_phosphorylation GO:0042325 12133 845 35 3 1820 5 2 false 0.4331901439903635 0.4331901439903635 0.0 cell_chemotaxis GO:0060326 12133 132 35 1 2155 9 3 false 0.43446069113291735 0.43446069113291735 6.49351277121459E-215 regulation_of_GTP_catabolic_process GO:0033124 12133 279 35 1 642 1 3 false 0.43457943925225373 0.43457943925225373 4.2701237450964594E-190 signal_transduction GO:0007165 12133 3547 35 12 6702 21 4 false 0.4348465243427969 0.4348465243427969 0.0 phagocytosis GO:0006909 12133 149 35 1 2417 9 2 false 0.4365289584880268 0.4365289584880268 3.130675140672653E-242 positive_regulation_of_response_to_tumor_cell GO:0002836 12133 7 35 1 16 1 3 false 0.4374999999999999 0.4374999999999999 8.741258741258732E-5 mRNA_stabilization GO:0048255 12133 22 35 2 33 2 2 false 0.43750000000000067 0.43750000000000067 5.166978132108427E-9 growth_factor_binding GO:0019838 12133 135 35 1 6397 27 1 false 0.43846598401075054 0.43846598401075054 1.7435678435075742E-283 leukocyte_activation_involved_in_immune_response GO:0002366 12133 119 35 1 475 2 2 false 0.43868532089721435 0.43868532089721435 1.7839978104873963E-115 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 35 4 723 5 2 false 0.4387270037513118 0.4387270037513118 2.0953844092707462E-201 extracellular_region_part GO:0044421 12133 740 35 3 10701 35 2 false 0.4396420255713157 0.4396420255713157 0.0 response_to_temperature_stimulus GO:0009266 12133 91 35 1 676 4 1 false 0.43993965567243637 0.43993965567243637 2.3046402907653703E-115 metallopeptidase_activity GO:0008237 12133 103 35 1 586 3 1 false 0.44066381473343075 0.44066381473343075 1.108136232226785E-117 response_to_chemical_stimulus GO:0042221 12133 2369 35 9 5200 18 1 false 0.4410328859811651 0.4410328859811651 0.0 response_to_salt_stress GO:0009651 12133 19 35 1 43 1 1 false 0.44186046511627686 0.44186046511627686 1.2492622608986976E-12 chromosome_organization GO:0051276 12133 689 35 3 2031 7 1 false 0.44298932592677964 0.44298932592677964 0.0 protein_tyrosine_kinase_activity GO:0004713 12133 180 35 1 1014 3 1 false 0.44395944842339685 0.44395944842339685 3.660578992202259E-205 negative_regulation_of_molecular_function GO:0044092 12133 735 35 3 10257 34 2 false 0.4441144936017277 0.4441144936017277 0.0 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 35 3 3447 12 2 false 0.44546109286897695 0.44546109286897695 0.0 establishment_of_localization GO:0051234 12133 2833 35 10 10446 34 2 false 0.4455669656584278 0.4455669656584278 0.0 regulation_of_Wnt_receptor_signaling_pathway GO:0030111 12133 156 35 1 1668 6 2 false 0.4457182439552707 0.4457182439552707 2.89270864030114E-224 transporter_activity GO:0005215 12133 746 35 3 10383 34 2 false 0.4458598727652351 0.4458598727652351 0.0 homeostatic_process GO:0042592 12133 990 35 4 2082 7 1 false 0.4464672790175934 0.4464672790175934 0.0 locomotion GO:0040011 12133 1045 35 4 10446 34 1 false 0.44659955626085357 0.44659955626085357 0.0 cellular_response_to_insulin_stimulus GO:0032869 12133 185 35 2 276 2 2 false 0.44848484848485837 0.44848484848485837 1.999097443178639E-75 positive_regulation_of_T_cell_activation GO:0050870 12133 145 35 1 323 1 3 false 0.4489164086687781 0.4489164086687781 7.1027996669547384E-96 nuclear_localization_sequence_binding GO:0008139 12133 9 35 1 20 1 1 false 0.45000000000000057 0.45000000000000057 5.9537985234579775E-6 mitochondrial_outer_membrane GO:0005741 12133 96 35 1 372 2 2 false 0.4500478219285001 0.4500478219285001 1.1824719222700171E-91 response_to_endogenous_stimulus GO:0009719 12133 982 35 4 5200 18 1 false 0.45045327737342217 0.45045327737342217 0.0 positive_regulation_of_interferon-alpha_production GO:0032727 12133 11 35 1 43 2 3 false 0.4507198228128468 0.4507198228128468 1.738524415708855E-10 developmental_process GO:0032502 12133 3447 35 12 10446 34 1 false 0.45110998262929736 0.45110998262929736 0.0 skeletal_muscle_fiber_development GO:0048741 12133 81 35 1 179 1 2 false 0.45251396648042663 0.45251396648042663 4.89646079793881E-53 single-organism_transport GO:0044765 12133 2323 35 9 8134 29 2 false 0.4526762043967316 0.4526762043967316 0.0 protein_localization_to_membrane GO:0072657 12133 94 35 1 1452 9 2 false 0.4534246649890659 0.4534246649890659 1.4056786116419224E-150 antigen_processing_and_presentation_of_peptide_or_polysaccharide_antigen_via_MHC_class_II GO:0002504 12133 84 35 1 185 1 1 false 0.4540540540540634 0.4540540540540634 7.577866882274746E-55 positive_regulation_of_GTPase_activity GO:0043547 12133 241 35 1 923 2 3 false 0.4542435658505244 0.4542435658505244 2.240962289646545E-229 regulation_of_biological_quality GO:0065008 12133 2082 35 7 6908 21 1 false 0.4550824758692368 0.4550824758692368 0.0 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 35 2 630 4 2 false 0.45541605160626936 0.45541605160626936 4.4826406352842784E-178 mitochondrial_envelope GO:0005740 12133 378 35 2 803 3 2 false 0.4560976070186449 0.4560976070186449 2.632819629334664E-240 intracellular_transport_of_viral_material GO:0075733 12133 23 35 1 355 9 2 false 0.4566430924840459 0.4566430924840459 1.1844258992565298E-36 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 35 7 5303 27 3 false 0.4566801926302333 0.4566801926302333 0.0 somatic_cell_DNA_recombination GO:0016444 12133 50 35 1 190 2 1 false 0.45808966861595624 0.45808966861595624 4.229558413024195E-47 regulation_of_peptidyl-tyrosine_phosphorylation GO:0050730 12133 150 35 1 812 3 2 false 0.45857103937838595 0.45857103937838595 5.072476466269739E-168 negative_regulation_of_cell_cycle GO:0045786 12133 298 35 2 3131 16 3 false 0.4588333924655962 0.4588333924655962 0.0 regulation_of_osteoblast_differentiation GO:0045667 12133 89 35 1 913 6 3 false 0.4605332789630892 0.4605332789630892 4.590259289121949E-126 localization GO:0051179 12133 3467 35 12 10446 34 1 false 0.4606263725384686 0.4606263725384686 0.0 microtubule_associated_complex GO:0005875 12133 110 35 1 3267 18 3 false 0.4610520838491302 0.4610520838491302 2.821671595839563E-208 regulation_of_ion_transmembrane_transport GO:0034765 12133 176 35 1 662 2 3 false 0.46133524687958344 0.46133524687958344 9.171243521861199E-166 apoptotic_nuclear_changes GO:0030262 12133 37 35 1 80 1 1 false 0.4625000000000024 0.4625000000000024 1.1618654074855353E-23 regulation_of_primary_metabolic_process GO:0080090 12133 3921 35 18 7507 33 2 false 0.46443312537949694 0.46443312537949694 0.0 positive_regulation_of_metabolic_process GO:0009893 12133 1872 35 8 8366 33 3 false 0.4652759714851106 0.4652759714851106 0.0 regulation_of_interleukin-6_production GO:0032675 12133 61 35 1 323 3 2 false 0.4674606299672687 0.4674606299672687 1.8817727061239984E-67 DNA-dependent_transcription,_initiation GO:0006352 12133 225 35 2 2751 19 2 false 0.46839293148226824 0.46839293148226824 0.0 regulation_of_ossification GO:0030278 12133 137 35 1 1586 7 2 false 0.469346338586261 0.469346338586261 7.69235263015688E-202 histone_modification GO:0016570 12133 306 35 2 2375 12 2 false 0.47023823329049586 0.47023823329049586 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 35 2 1384 11 2 false 0.4730073839518078 0.4730073839518078 1.3395090025049634E-243 regulation_of_stress-activated_protein_kinase_signaling_cascade GO:0070302 12133 147 35 1 765 3 3 false 0.47328580887173843 0.47328580887173843 7.281108340064304E-162 regulation_of_cellular_component_size GO:0032535 12133 157 35 1 7666 31 3 false 0.4741526361169677 0.4741526361169677 0.0 morphogenesis_of_an_epithelium GO:0002009 12133 328 35 1 691 1 2 false 0.47467438494931047 0.47467438494931047 7.776670515222191E-207 DNA_metabolic_process GO:0006259 12133 791 35 5 5627 32 2 false 0.4748827482943382 0.4748827482943382 0.0 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 35 4 307 5 1 false 0.4750081552181268 0.4750081552181268 1.4733469150792184E-83 response_to_insulin_stimulus GO:0032868 12133 216 35 2 313 2 1 false 0.4755468173998091 0.4755468173998091 1.4650294580642456E-83 morphogenesis_of_a_branching_epithelium GO:0061138 12133 160 35 1 336 1 2 false 0.4761904761905091 0.4761904761905091 2.40154258695507E-100 contractile_fiber_part GO:0044449 12133 144 35 1 7199 32 3 false 0.4769027041065658 0.4769027041065658 8.364096489052254E-306 chromatin_organization GO:0006325 12133 539 35 3 689 3 1 false 0.47816846296944454 0.47816846296944454 4.375882251809235E-156 regulation_of_systemic_arterial_blood_pressure GO:0003073 12133 56 35 1 117 1 1 false 0.4786324786324643 0.4786324786324643 9.090542259133476E-35 cell_activation_involved_in_immune_response GO:0002263 12133 119 35 1 1341 7 3 false 0.4790063262438652 0.4790063262438652 8.435334491810511E-174 positive_regulation_of_cellular_catabolic_process GO:0031331 12133 106 35 1 3311 20 4 false 0.4793456370658762 0.4793456370658762 4.802217577498734E-203 monovalent_inorganic_cation_transmembrane_transporter_activity GO:0015077 12133 198 35 1 413 1 2 false 0.47941888619856315 0.47941888619856315 1.708187099767858E-123 muscle_structure_development GO:0061061 12133 413 35 2 3152 12 2 false 0.47947921439653385 0.47947921439653385 0.0 microtubule GO:0005874 12133 288 35 2 3267 18 3 false 0.48003956079370597 0.48003956079370597 0.0 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 35 1 1054 7 3 false 0.4810047084882726 0.4810047084882726 5.573854633657796E-137 regulation_of_signal_transduction GO:0009966 12133 1603 35 6 3826 13 4 false 0.48189288382540685 0.48189288382540685 0.0 amide_binding GO:0033218 12133 182 35 1 8962 32 1 false 0.4819555556666431 0.4819555556666431 0.0 negative_regulation_of_organelle_organization GO:0010639 12133 168 35 1 2125 8 3 false 0.48315219983754865 0.48315219983754865 2.2467097914760192E-254 purine_nucleoside_catabolic_process GO:0006152 12133 939 35 5 1085 5 3 false 0.4847915589422494 0.4847915589422494 2.1746006434797338E-185 cytokine-mediated_signaling_pathway GO:0019221 12133 318 35 2 2013 10 2 false 0.48507248746261095 0.48507248746261095 0.0 positive_regulation_of_protein_modification_process GO:0031401 12133 708 35 4 2417 12 3 false 0.4857222224343939 0.4857222224343939 0.0 small_molecule_binding GO:0036094 12133 2102 35 8 8962 32 1 false 0.48597878812528017 0.48597878812528017 0.0 embryonic_morphogenesis GO:0048598 12133 406 35 2 2812 11 3 false 0.48641774511785507 0.48641774511785507 0.0 response_to_cytokine_stimulus GO:0034097 12133 461 35 2 1783 6 1 false 0.48643298746162306 0.48643298746162306 0.0 organelle_envelope GO:0031967 12133 629 35 3 7756 32 3 false 0.4869495420444101 0.4869495420444101 0.0 DNA_geometric_change GO:0032392 12133 55 35 1 194 2 1 false 0.4876876235243701 0.4876876235243701 9.185000733353143E-50 DNA_biosynthetic_process GO:0071897 12133 268 35 2 3979 24 3 false 0.48783071757176133 0.48783071757176133 0.0 regulation_of_protein_import_into_nucleus GO:0042306 12133 121 35 1 248 1 4 false 0.48790322580649104 0.48790322580649104 4.6955049394038436E-74 carbohydrate_biosynthetic_process GO:0016051 12133 132 35 1 4212 21 2 false 0.48843012741594455 0.48843012741594455 3.288354819591378E-254 protein_C-terminus_binding GO:0008022 12133 157 35 1 6397 27 1 false 0.4894700632401348 0.4894700632401348 2.34014E-319 protein_maturation GO:0051604 12133 123 35 1 5551 30 2 false 0.49033551202779646 0.49033551202779646 1.3126924681575497E-255 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 35 1 417 1 4 false 0.4916067146282839 0.4916067146282839 8.022991700655629E-125 contractile_fiber GO:0043292 12133 159 35 1 6670 28 2 false 0.49182954957315655 0.49182954957315655 0.0 epithelial_cell_migration GO:0010631 12133 130 35 2 185 2 2 false 0.4926556991774518 0.4926556991774518 1.9916445787710798E-48 ubiquitin-protein_ligase_activity GO:0004842 12133 321 35 4 558 6 2 false 0.4929154464780892 0.4929154464780892 1.7708856343357755E-164 regulation_of_reproductive_process GO:2000241 12133 171 35 1 6891 27 2 false 0.4932599233351038 0.4932599233351038 0.0 gastrulation GO:0007369 12133 117 35 1 406 2 1 false 0.4938149972632736 0.4938149972632736 2.9879060124816245E-105 regulation_of_multicellular_organismal_development GO:2000026 12133 953 35 4 3481 13 3 false 0.49518155188375523 0.49518155188375523 0.0 tRNA_processing GO:0008033 12133 65 35 1 225 2 2 false 0.4952380952380675 0.4952380952380675 3.0877085821775332E-58 regulation_of_cell_communication GO:0010646 12133 1796 35 6 6469 20 2 false 0.495350621506552 0.495350621506552 0.0 response_to_interferon-gamma GO:0034341 12133 97 35 1 900 6 2 false 0.49654569197003107 0.49654569197003107 5.665951698458868E-133 monovalent_inorganic_cation_transport GO:0015672 12133 302 35 1 606 1 1 false 0.49834983498356933 0.49834983498356933 1.1660817479890875E-181 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 35 1 527 1 2 false 0.49905123339657426 0.49905123339657426 6.55805140577772E-158 DNA_topoisomerase_type_I_activity GO:0003917 12133 4 35 1 8 1 1 false 0.4999999999999997 0.4999999999999997 0.014285714285714268 peptidyl-tyrosine_phosphorylation GO:0018108 12133 191 35 1 1195 4 2 false 0.5022084574603523 0.5022084574603523 2.9198379950600046E-227 chromatin_remodeling GO:0006338 12133 95 35 1 458 3 1 false 0.5029776977249808 0.5029776977249808 6.184896180355641E-101 DNA_replication GO:0006260 12133 257 35 2 3702 24 3 false 0.5043444607440399 0.5043444607440399 0.0 catalytic_step_2_spliceosome GO:0071013 12133 76 35 2 151 3 3 false 0.5050002222321203 0.5050002222321203 5.422089502503699E-45 cysteine-type_peptidase_activity GO:0008234 12133 295 35 2 586 3 1 false 0.505128145188445 0.505128145188445 1.2148857586981575E-175 regulation_of_signaling GO:0023051 12133 1793 35 6 6715 21 2 false 0.5054463442833428 0.5054463442833428 0.0 peptidyl-lysine_modification GO:0018205 12133 185 35 1 623 2 1 false 0.5060566804127797 0.5060566804127797 7.634244791194444E-164 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_II GO:0002495 12133 83 35 1 164 1 2 false 0.5060975609756246 0.5060975609756246 6.958070805209033E-49 interaction_with_host GO:0051701 12133 387 35 9 417 9 2 false 0.5072546828009932 0.5072546828009932 1.9217516081652173E-46 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 35 4 10311 34 3 false 0.5078245384464962 0.5078245384464962 0.0 helicase_activity GO:0004386 12133 140 35 1 1059 5 1 false 0.508559320218527 0.508559320218527 6.632628106941949E-179 negative_regulation_of_immune_system_process GO:0002683 12133 144 35 1 3524 17 3 false 0.5088012338833376 0.5088012338833376 1.8096661454151343E-260 B_cell_differentiation GO:0030183 12133 78 35 1 260 2 2 false 0.51081081081084 0.51081081081084 1.9566405478463094E-68 cellular_chemical_homeostasis GO:0055082 12133 525 35 2 734 2 2 false 0.5113173810732686 0.5113173810732686 1.1478565010718528E-189 negative_regulation_of_BMP_signaling_pathway GO:0030514 12133 27 35 1 128 3 3 false 0.5118285995500623 0.5118285995500623 2.661630263374797E-28 neuron_projection GO:0043005 12133 534 35 2 1043 3 2 false 0.5179908112521974 0.5179908112521974 5.7946905775E-313 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_II GO:0019886 12133 80 35 1 154 1 2 false 0.5194805194805144 0.5194805194805144 7.662175327238918E-46 peptidyl-tyrosine_modification GO:0018212 12133 191 35 1 623 2 1 false 0.5195119559440001 0.5195119559440001 5.019013158282893E-166 regulation_of_leukocyte_mediated_immunity GO:0002703 12133 84 35 1 274 2 2 false 0.5199326221222871 0.5199326221222871 8.733942624679482E-73 regulation_of_adaptive_immune_response GO:0002819 12133 78 35 1 570 5 2 false 0.5222107125369458 0.5222107125369458 3.127506712292269E-98 regulation_of_molecular_function GO:0065009 12133 2079 35 7 10494 34 2 false 0.522978277714409 0.522978277714409 0.0 NAD-dependent_histone_deacetylase_activity_(H3-K14_specific) GO:0032041 12133 11 35 2 15 2 2 false 0.5238095238095232 0.5238095238095232 7.326007326007312E-4 NAD-dependent_histone_deacetylase_activity_(H4-K16_specific) GO:0046970 12133 11 35 2 15 2 2 false 0.5238095238095232 0.5238095238095232 7.326007326007312E-4 glycosyl_compound_metabolic_process GO:1901657 12133 1093 35 5 7599 33 2 false 0.524914466622365 0.524914466622365 0.0 regulation_of_ion_transport GO:0043269 12133 307 35 1 1393 3 2 false 0.5264439777398165 0.5264439777398165 3.368915E-318 cell_cortex GO:0005938 12133 175 35 1 6402 27 2 false 0.5275724199606233 0.5275724199606233 0.0 microtubule_motor_activity GO:0003777 12133 56 35 1 106 1 1 false 0.5283018867924546 0.5283018867924546 1.8864820707878306E-31 extracellular_region GO:0005576 12133 1152 35 4 10701 35 1 false 0.5291887726988831 0.5291887726988831 0.0 multicellular_organismal_process GO:0032501 12133 4223 35 14 10446 34 1 false 0.5296626765100353 0.5296626765100353 0.0 regulation_of_stress-activated_MAPK_cascade GO:0032872 12133 146 35 1 463 2 3 false 0.5317008405563531 0.5317008405563531 1.1657182873431035E-124 intracellular_receptor_signaling_pathway GO:0030522 12133 217 35 1 3547 12 1 false 0.5317597315612764 0.5317597315612764 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 35 1 86 2 2 false 0.5318741450068484 0.5318741450068484 6.233113581740502E-23 ribonucleoside_catabolic_process GO:0042454 12133 946 35 5 1073 5 2 false 0.5320005406987649 0.5320005406987649 9.25790942536024E-169 B_cell_homeostasis GO:0001782 12133 23 35 1 43 1 1 false 0.534883720930229 0.534883720930229 1.0410518840822442E-12 spindle_organization GO:0007051 12133 78 35 1 1776 17 3 false 0.5356206811172529 0.5356206811172529 2.2015050227101385E-138 anion_binding GO:0043168 12133 2280 35 7 4448 13 1 false 0.5369243903211656 0.5369243903211656 0.0 lyase_activity GO:0016829 12133 230 35 1 4901 16 1 false 0.5371098882539043 0.5371098882539043 0.0 positive_regulation_of_intracellular_transport GO:0032388 12133 126 35 1 1370 8 3 false 0.5387928642158446 0.5387928642158446 5.304932497681123E-182 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 35 5 1054 5 2 false 0.5399275587687933 0.5399275587687933 2.3625686453162704E-163 regulation_of_multi-organism_process GO:0043900 12133 193 35 1 6817 27 2 false 0.5401919664353276 0.5401919664353276 0.0 B_cell_mediated_immunity GO:0019724 12133 92 35 1 170 1 2 false 0.541176470588214 0.541176470588214 1.940857539818752E-50 protein_localization_to_plasma_membrane GO:0072659 12133 65 35 1 120 1 2 false 0.5416666666666762 0.5416666666666762 1.56537040183633E-35 negative_regulation_of_intracellular_protein_kinase_cascade GO:0010741 12133 140 35 1 1142 6 3 false 0.5445822678060002 0.5445822678060002 8.254846485029262E-184 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 35 5 1060 5 3 false 0.5448401233302466 0.5448401233302466 8.715047292960447E-163 ncRNA_metabolic_process GO:0034660 12133 258 35 2 3294 23 1 false 0.5481102243881797 0.5481102243881797 0.0 regulation_of_T_cell_activation GO:0050863 12133 186 35 1 339 1 2 false 0.548672566371674 0.548672566371674 1.0254523445533855E-100 regulation_of_cellular_component_organization GO:0051128 12133 1152 35 5 7336 31 2 false 0.5497910345830603 0.5497910345830603 0.0 nuclear_import GO:0051170 12133 203 35 1 2389 9 3 false 0.5509478088474808 0.5509478088474808 7.452348105569065E-301 ncRNA_processing GO:0034470 12133 186 35 2 649 6 2 false 0.5511543155709254 0.5511543155709254 4.048832162241149E-168 regulation_of_cell_projection_organization GO:0031344 12133 227 35 1 1532 5 2 false 0.5520138648405455 0.5520138648405455 2.603761260472357E-278 activation_of_MAPK_activity GO:0000187 12133 158 35 1 286 1 2 false 0.5524475524475345 0.5524475524475345 8.207976102051858E-85 sequence-specific_DNA_binding GO:0043565 12133 1189 35 6 2091 10 1 false 0.5529051348190822 0.5529051348190822 0.0 catalytic_activity GO:0003824 12133 4901 35 16 10478 34 2 false 0.5536214008946531 0.5536214008946531 0.0 myeloid_cell_differentiation GO:0030099 12133 237 35 1 2177 7 2 false 0.5542511486482581 0.5542511486482581 0.0 regulation_of_protein_localization GO:0032880 12133 349 35 2 2148 11 2 false 0.5548109517779117 0.5548109517779117 0.0 trophoblast_giant_cell_differentiation GO:0060707 12133 10 35 1 18 1 1 false 0.5555555555555578 0.5555555555555578 2.2852964029434708E-5 centrosome GO:0005813 12133 327 35 2 3226 18 2 false 0.5580392909999616 0.5580392909999616 0.0 skeletal_muscle_organ_development GO:0060538 12133 172 35 1 308 1 1 false 0.5584415584415203 0.5584415584415203 3.4535917571053045E-91 response_to_organic_nitrogen GO:0010243 12133 519 35 2 1787 6 3 false 0.559195925939085 0.559195925939085 0.0 ossification GO:0001503 12133 234 35 1 4095 14 1 false 0.5618162163119742 0.5618162163119742 0.0 monosaccharide_metabolic_process GO:0005996 12133 217 35 1 385 1 1 false 0.5636363636363345 0.5636363636363345 7.061110236111427E-114 carbohydrate_catabolic_process GO:0016052 12133 112 35 1 2356 17 2 false 0.5643363129260388 0.5643363129260388 5.972721726257644E-195 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 35 2 1379 4 2 false 0.565127740522108 0.565127740522108 0.0 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 35 1 53 1 2 false 0.5660377358490526 0.5660377358490526 1.6040955778771873E-15 positive_regulation_of_catabolic_process GO:0009896 12133 137 35 1 3517 21 3 false 0.5669124422594294 0.5669124422594294 1.0965595914697655E-250 regulation_of_proteolysis GO:0030162 12133 146 35 1 1822 10 2 false 0.5671687337412563 0.5671687337412563 4.197674460173735E-220 cellular_macromolecular_complex_assembly GO:0034622 12133 517 35 4 973 7 1 false 0.5685113537469348 0.5685113537469348 3.312522477266262E-291 regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010769 12133 167 35 1 879 4 3 false 0.5701993304022286 0.5701993304022286 7.212819447877608E-185 protein_import GO:0017038 12133 225 35 1 2509 9 2 false 0.5713097352003955 0.5713097352003955 0.0 substrate-specific_transporter_activity GO:0022892 12133 620 35 3 746 3 1 false 0.5735915936445926 0.5735915936445926 1.886990037563331E-146 nucleolus GO:0005730 12133 1357 35 9 4208 28 3 false 0.5757305539295916 0.5757305539295916 0.0 striated_muscle_cell_differentiation GO:0051146 12133 203 35 2 267 2 1 false 0.5773703922728246 0.5773703922728246 2.4098375851666058E-63 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 35 2 201 10 3 false 0.579691091674413 0.579691091674413 2.854176062301069E-41 positive_regulation_of_transport GO:0051050 12133 413 35 2 4769 22 3 false 0.5799247861482679 0.5799247861482679 0.0 regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032434 12133 57 35 1 227 3 2 false 0.5818538588489612 0.5818538588489612 4.5524072103258975E-55 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 35 3 1304 3 1 false 0.5821746997452448 0.5821746997452448 1.004636319027547E-252 purine_nucleotide_binding GO:0017076 12133 1650 35 7 1997 8 1 false 0.5824375002612512 0.5824375002612512 0.0 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 35 2 2776 8 3 false 0.5828987422659726 0.5828987422659726 0.0 protein-DNA_complex GO:0032993 12133 110 35 1 3462 27 1 false 0.5832025397047598 0.5832025397047598 4.3156565695482125E-211 skeletal_muscle_tissue_development GO:0007519 12133 168 35 1 288 1 2 false 0.5833333333332881 0.5833333333332881 2.348024843062379E-84 ribonucleotide_binding GO:0032553 12133 1651 35 7 1997 8 1 false 0.5839909157829053 0.5839909157829053 0.0 cellular_response_to_stimulus GO:0051716 12133 4236 35 15 7871 28 2 false 0.5870946411294484 0.5870946411294484 0.0 JNK_cascade GO:0007254 12133 159 35 2 207 2 1 false 0.5891374700998838 0.5891374700998838 3.1556682987155503E-48 regulation_of_cellular_response_to_stress GO:0080135 12133 270 35 1 6503 21 3 false 0.5901338911270098 0.5901338911270098 0.0 endothelial_cell_migration GO:0043542 12133 100 35 2 130 2 1 false 0.5903398926654729 0.5903398926654729 3.8279880512589226E-30 protein_modification_by_small_protein_removal GO:0070646 12133 77 35 1 645 7 1 false 0.5911258602827024 0.5911258602827024 7.565398504158586E-102 response_to_growth_factor_stimulus GO:0070848 12133 545 35 2 1783 6 1 false 0.5922985932551612 0.5922985932551612 0.0 regulation_of_catalytic_activity GO:0050790 12133 1692 35 6 6953 25 3 false 0.5923116530549357 0.5923116530549357 0.0 activation_of_protein_kinase_activity GO:0032147 12133 247 35 1 417 1 1 false 0.5923261390887407 0.5923261390887407 9.475379918718814E-122 basal_RNA_polymerase_II_transcription_machinery_binding GO:0001099 12133 76 35 1 464 5 1 false 0.592880180834193 0.592880180834193 2.7883330382309735E-89 cellular_component_organization GO:0016043 12133 3745 35 21 3839 21 1 false 0.5933479614571868 0.5933479614571868 4.153510440731863E-191 DNA-dependent_DNA_replication GO:0006261 12133 93 35 1 257 2 1 false 0.5936892023346113 0.5936892023346113 1.72483826119428E-72 muscle_tissue_development GO:0060537 12133 295 35 1 1132 3 1 false 0.5961400979081191 0.5961400979081191 3.412889797328503E-281 receptor_complex GO:0043235 12133 146 35 1 2976 18 1 false 0.596720062426462 0.596720062426462 3.091225804524361E-252 mitotic_cell_cycle GO:0000278 12133 625 35 4 1295 8 1 false 0.5984295890176032 0.5984295890176032 0.0 phosphatase_binding GO:0019902 12133 108 35 1 1005 8 1 false 0.5986285340517059 0.5986285340517059 3.014042549641288E-148 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 35 1 650 3 2 false 0.6004706122502991 0.6004706122502991 6.010278185218431E-162 regulation_of_anatomical_structure_size GO:0090066 12133 256 35 1 2082 7 1 false 0.6014114375174263 0.6014114375174263 0.0 purine_nucleotide_metabolic_process GO:0006163 12133 1208 35 5 1337 5 2 false 0.6016306260293018 0.6016306260293018 1.5771526523631757E-183 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 35 2 541 4 2 false 0.6021111877600176 0.6021111877600176 1.01164377942614E-160 protein_tetramerization GO:0051262 12133 76 35 1 288 3 1 false 0.6026280629938624 0.6026280629938624 1.240191410365077E-71 protein_stabilization GO:0050821 12133 60 35 1 99 1 1 false 0.6060606060605888 0.6060606060605888 1.818679918792965E-28 positive_regulation_of_intracellular_protein_transport GO:0090316 12133 92 35 1 737 7 4 false 0.6083759893036031 0.6083759893036031 7.301092489476398E-120 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 35 1 341 4 4 false 0.6087877863200334 0.6087877863200334 3.257446469032824E-75 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 35 1 759 7 3 false 0.609380094857505 0.609380094857505 1.1458874617943115E-123 developmental_growth GO:0048589 12133 223 35 1 2952 12 2 false 0.6110886655406123 0.6110886655406123 0.0 immune_response-activating_signal_transduction GO:0002757 12133 299 35 3 352 3 2 false 0.6119642857143206 0.6119642857143206 2.8561568566531905E-64 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 35 1 147 1 1 false 0.6122448979591654 0.6122448979591654 3.485982605742994E-42 chromatin_modification GO:0016568 12133 458 35 3 539 3 1 false 0.6129163324296396 0.6129163324296396 1.802023694196357E-98 regulation_of_nervous_system_development GO:0051960 12133 381 35 1 1805 4 2 false 0.612970284335919 0.612970284335919 0.0 adaptive_immune_response GO:0002250 12133 174 35 1 1006 5 1 false 0.6138812425403213 0.6138812425403213 1.8321069442753992E-200 establishment_of_cell_polarity GO:0030010 12133 64 35 1 104 1 1 false 0.615384615384606 0.615384615384606 1.0052317592714408E-29 somatic_diversification_of_immunoglobulins GO:0016445 12133 45 35 1 73 1 2 false 0.6164383561643858 0.6164383561643858 8.158943815315171E-21 ion_homeostasis GO:0050801 12133 532 35 2 677 2 1 false 0.6172637724733726 0.6172637724733726 5.041033537922393E-152 large_ribosomal_subunit GO:0015934 12133 73 35 4 132 7 1 false 0.6173619452040982 0.6173619452040982 5.5437540818743186E-39 antigen_processing_and_presentation GO:0019882 12133 185 35 1 1618 8 1 false 0.6222817938287893 0.6222817938287893 5.091289488805967E-249 negative_regulation_of_cytokine_production GO:0001818 12133 114 35 1 529 4 3 false 0.6224193310263393 0.6224193310263393 4.407958658606205E-119 virus-host_interaction GO:0019048 12133 355 35 9 588 15 2 false 0.6225789441751737 0.6225789441751737 1.0104535019427035E-170 regulation_of_cell_activation GO:0050865 12133 303 35 1 6351 20 2 false 0.6243865738520565 0.6243865738520565 0.0 positive_regulation_of_phosphorylation GO:0042327 12133 563 35 2 1487 5 3 false 0.6254381459521137 0.6254381459521137 0.0 NAD-dependent_histone_deacetylase_activity_(H3-K18_specific) GO:0097372 12133 12 35 2 15 2 2 false 0.628571428571428 0.628571428571428 0.002197802197802196 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 35 1 178 1 1 false 0.629213483146089 0.629213483146089 1.7238002808689451E-50 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 35 2 2896 12 3 false 0.6293257026902155 0.6293257026902155 0.0 ribonucleotide_metabolic_process GO:0009259 12133 1202 35 5 1318 5 2 false 0.630414987777399 0.630414987777399 7.680938106405399E-170 ion_transmembrane_transporter_activity GO:0015075 12133 469 35 2 589 2 2 false 0.6337618239145896 0.6337618239145896 1.1842155919657181E-128 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 35 4 1975 10 1 false 0.6345027790148483 0.6345027790148483 0.0 lymphocyte_proliferation GO:0046651 12133 160 35 1 404 2 2 false 0.6358253691373246 0.6358253691373246 3.946230420659752E-117 positive_regulation_of_protein_transport GO:0051222 12133 154 35 1 1301 8 3 false 0.6360607783329769 0.6360607783329769 9.736449433094532E-205 cytokinesis GO:0000910 12133 111 35 1 1047 9 2 false 0.6367702493214511 0.6367702493214511 4.556333438415199E-153 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 35 4 504 5 1 false 0.6370158465671776 0.6370158465671776 6.011520399617331E-122 ribosome_biogenesis GO:0042254 12133 144 35 2 243 3 1 false 0.6378585299747147 0.6378585299747147 8.984879194471426E-71 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 35 13 3120 16 4 false 0.6379333935106821 0.6379333935106821 0.0 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 35 2 3702 12 3 false 0.6407463319913217 0.6407463319913217 0.0 activation_of_cysteine-type_endopeptidase_activity GO:0097202 12133 85 35 2 106 2 1 false 0.6415094339622428 0.6415094339622428 1.25561322378657E-22 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 35 3 381 5 2 false 0.6436061629461944 0.6436061629461944 4.820433761728018E-112 RNA_polymerase_II_transcription_factor_binding GO:0001085 12133 133 35 1 715 5 1 false 0.6438031004109904 0.6438031004109904 1.758868350294454E-148 organelle_inner_membrane GO:0019866 12133 264 35 1 9083 35 3 false 0.6445347438465772 0.6445347438465772 0.0 tRNA_metabolic_process GO:0006399 12133 104 35 1 258 2 1 false 0.6446475432087663 0.6446475432087663 5.594663773224907E-75 leukocyte_differentiation GO:0002521 12133 299 35 1 2177 7 2 false 0.6450299733336113 0.6450299733336113 0.0 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 35 1 195 3 4 false 0.6478360376870552 0.6478360376870552 1.081664723883568E-50 protein_heterodimerization_activity GO:0046982 12133 317 35 1 779 2 1 false 0.6485805082650417 0.6485805082650417 8.49214053182804E-228 cellular_homeostasis GO:0019725 12133 585 35 2 7566 28 2 false 0.6489507039183715 0.6489507039183715 0.0 signaling GO:0023052 12133 3878 35 12 10446 34 1 false 0.6499217396329209 0.6499217396329209 0.0 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 35 2 1356 5 2 false 0.650031361290332 0.650031361290332 0.0 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 35 2 1192 8 2 false 0.6502297271033178 0.6502297271033178 5.168872172755415E-294 transmembrane_transporter_activity GO:0022857 12133 544 35 2 904 3 2 false 0.6507090708704448 0.6507090708704448 4.222056161945909E-263 hydro-lyase_activity GO:0016836 12133 28 35 1 43 1 1 false 0.6511627906976691 0.6511627906976691 6.59923756240987E-12 regulation_of_biological_process GO:0050789 12133 6622 35 21 10446 34 2 false 0.6512106483440249 0.6512106483440249 0.0 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 35 1 835 4 2 false 0.6534717171170541 0.6534717171170541 8.0742416973675315E-196 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 35 2 129 3 1 false 0.6558694607215028 0.6558694607215028 3.5310664374642874E-37 establishment_of_protein_localization_to_plasma_membrane GO:0090002 12133 44 35 1 67 1 2 false 0.6567164179104545 0.6567164179104545 1.8842771584909833E-18 regulation_of_BMP_signaling_pathway GO:0030510 12133 48 35 1 161 3 2 false 0.6570139458572952 0.6570139458572952 3.648915121282221E-42 response_to_nitrogen_compound GO:1901698 12133 552 35 2 2369 9 1 false 0.6574711033749003 0.6574711033749003 0.0 regulation_of_cellular_localization GO:0060341 12133 603 35 2 6869 25 3 false 0.6580250511050435 0.6580250511050435 0.0 rRNA_metabolic_process GO:0016072 12133 107 35 1 258 2 1 false 0.6584019545741964 0.6584019545741964 1.860360860420455E-75 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 35 1 2025 11 2 false 0.6585604419295352 0.6585604419295352 5.184659787643375E-271 nucleotide_binding GO:0000166 12133 1997 35 8 2103 8 2 false 0.6606974981994602 0.6606974981994602 1.0169073992212018E-181 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 35 2 86 2 2 false 0.6607387140902996 0.6607387140902996 1.0344828145516245E-17 positive_regulation_of_hydrolase_activity GO:0051345 12133 562 35 2 2891 11 3 false 0.66154145792074 0.66154145792074 0.0 lymphocyte_differentiation GO:0030098 12133 203 35 1 485 2 2 false 0.6624265144415058 0.6624265144415058 1.747932496277033E-142 negative_regulation_of_apoptotic_process GO:0043066 12133 537 35 3 1377 8 3 false 0.6638876954230812 0.6638876954230812 0.0 cellular_protein_complex_assembly GO:0043623 12133 284 35 2 958 7 2 false 0.6638920301130531 0.6638920301130531 4.57678794545446E-252 hydrolase_activity GO:0016787 12133 2556 35 8 4901 16 1 false 0.66433925015068 0.66433925015068 0.0 vesicle GO:0031982 12133 834 35 3 7980 32 1 false 0.6645699920765645 0.6645699920765645 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 35 2 701 3 2 false 0.6653941159643172 0.6653941159643172 1.5434745144062482E-202 apoptotic_protease_activator_activity GO:0016505 12133 22 35 1 33 1 1 false 0.6666666666666647 0.6666666666666647 5.166978132108427E-9 RNA_polymerase_core_enzyme_binding GO:0043175 12133 10 35 1 15 1 1 false 0.6666666666666671 0.6666666666666671 3.330003330003327E-4 response_to_hormone_stimulus GO:0009725 12133 611 35 2 1784 6 2 false 0.667052487103675 0.667052487103675 0.0 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 35 5 1007 5 2 false 0.6676794120268628 0.6676794120268628 1.4040993054667365E-118 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 35 4 3771 21 4 false 0.668881107610769 0.668881107610769 0.0 embryonic_organ_development GO:0048568 12133 275 35 1 2873 11 3 false 0.6700437046051579 0.6700437046051579 0.0 positive_regulation_of_cell_activation GO:0050867 12133 215 35 1 3002 15 3 false 0.67287144979681 0.67287144979681 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 35 3 147 3 1 false 0.6738530650805338 0.6738530650805338 1.843896992838607E-23 response_to_inorganic_substance GO:0010035 12133 277 35 1 2369 9 1 false 0.6740931533184193 0.6740931533184193 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 35 2 442 4 3 false 0.6746252541508964 0.6746252541508964 2.4953498472018727E-132 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 35 5 1006 5 2 false 0.674638232892963 0.674638232892963 2.1893990019353197E-116 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 35 4 4044 21 3 false 0.6757025230712899 0.6757025230712899 0.0 single-multicellular_organism_process GO:0044707 12133 4095 35 14 8057 29 2 false 0.6775627739184474 0.6775627739184474 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 35 2 129 3 1 false 0.6781038271379052 0.6781038271379052 8.751505837166389E-37 signal_transduction_by_phosphorylation GO:0023014 12133 307 35 1 3947 14 2 false 0.6787574258531777 0.6787574258531777 0.0 immunoglobulin_production GO:0002377 12133 64 35 1 94 1 1 false 0.68085106382981 0.68085106382981 3.0952886871689963E-25 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 35 2 252 3 2 false 0.6814949724909695 0.6814949724909695 5.925442745937436E-72 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 35 7 7638 33 4 false 0.6815710738633098 0.6815710738633098 0.0 response_to_metal_ion GO:0010038 12133 189 35 1 277 1 1 false 0.6823104693141068 0.6823104693141068 1.2236423246824455E-74 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 35 2 1804 7 2 false 0.6824469438535037 0.6824469438535037 0.0 activating_transcription_factor_binding GO:0033613 12133 294 35 2 715 5 1 false 0.6828605904086976 0.6828605904086976 1.6086726333731214E-209 apoptotic_DNA_fragmentation GO:0006309 12133 26 35 1 38 1 2 false 0.6842105263157929 0.6842105263157929 3.6934780388979485E-10 cell-matrix_adhesion GO:0007160 12133 130 35 1 190 1 1 false 0.6842105263158172 0.6842105263158172 5.558763172566491E-51 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 35 5 1002 5 3 false 0.6845391878397185 0.6845391878397185 5.68242981185093E-113 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 35 1 971 13 2 false 0.6847712466408473 0.6847712466408473 1.7939571902377886E-121 response_to_drug GO:0042493 12133 286 35 1 2369 9 1 false 0.6865203065936452 0.6865203065936452 0.0 cellular_ion_homeostasis GO:0006873 12133 478 35 2 575 2 2 false 0.6908226026360981 0.6908226026360981 1.064446434652655E-112 leukocyte_activation GO:0045321 12133 475 35 2 1729 8 2 false 0.6920260794500916 0.6920260794500916 0.0 protein_phosphatase_binding GO:0019903 12133 75 35 1 108 1 1 false 0.694444444444449 0.694444444444449 1.6262935863243163E-28 circadian_rhythm GO:0007623 12133 66 35 1 148 2 1 false 0.6947049089905517 0.6947049089905517 1.0122432742541851E-43 small_molecule_metabolic_process GO:0044281 12133 2423 35 6 2877 7 1 false 0.6947416785964116 0.6947416785964116 0.0 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 35 1 254 3 3 false 0.696626977951671 0.696626977951671 3.7262148804586973E-69 positive_regulation_of_lymphocyte_activation GO:0051251 12133 188 35 1 419 2 3 false 0.6966461499814122 0.6966461499814122 1.71987955515036E-124 muscle_organ_development GO:0007517 12133 308 35 1 1966 7 2 false 0.6972088010460822 0.6972088010460822 0.0 small_ribosomal_subunit GO:0015935 12133 60 35 3 132 7 1 false 0.697816884952946 0.697816884952946 4.556510204279982E-39 regulation_of_response_to_external_stimulus GO:0032101 12133 314 35 1 2524 9 2 false 0.698113230333328 0.698113230333328 0.0 regulation_of_biosynthetic_process GO:0009889 12133 3012 35 14 5483 27 2 false 0.6984597999326198 0.6984597999326198 0.0 cell_differentiation GO:0030154 12133 2154 35 7 2267 7 1 false 0.6987917792378382 0.6987917792378382 2.602261335719434E-194 protein_homooligomerization GO:0051260 12133 183 35 2 288 3 1 false 0.6988174427198101 0.6988174427198101 1.8197847122731807E-81 muscle_fiber_development GO:0048747 12133 93 35 1 133 1 1 false 0.6992481203007894 0.6992481203007894 6.346042881794858E-35 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 35 2 129 3 1 false 0.6999834050540257 0.6999834050540257 2.4714073881998435E-36 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 35 1 140 1 1 false 0.6999999999999931 0.6999999999999931 9.838676628741767E-37 leukocyte_migration GO:0050900 12133 224 35 1 1975 10 2 false 0.7008284797495778 0.7008284797495778 1.7898344026900835E-302 regulation_of_neurogenesis GO:0050767 12133 344 35 1 1039 3 4 false 0.7011275716856009 0.7011275716856009 1.1807712079388562E-285 macromolecule_modification GO:0043412 12133 2461 35 12 6052 32 1 false 0.7042730924183174 0.7042730924183174 0.0 cell-cell_junction_organization GO:0045216 12133 152 35 2 181 2 1 false 0.704481276857021 0.704481276857021 3.1886200066761254E-34 nucleoside_binding GO:0001882 12133 1639 35 7 4455 21 3 false 0.7054460314426593 0.7054460314426593 0.0 regulation_of_protein_complex_assembly GO:0043254 12133 185 35 1 1610 10 3 false 0.7060270616092217 0.7060270616092217 1.34790682725651E-248 defense_response_to_virus GO:0051607 12133 160 35 1 1130 8 3 false 0.7063954903180347 0.7063954903180347 2.076664675339186E-199 synapse GO:0045202 12133 368 35 1 10701 35 1 false 0.7067686492856813 0.7067686492856813 0.0 neuron_projection_development GO:0031175 12133 575 35 1 812 1 2 false 0.7081280788176632 0.7081280788176632 3.771933680434825E-212 somatic_diversification_of_immunoglobulins_involved_in_immune_response GO:0002208 12133 34 35 1 48 1 2 false 0.708333333333333 0.708333333333333 2.0733096446974964E-12 negative_regulation_of_cell_death GO:0060548 12133 567 35 3 3054 19 3 false 0.7136000268597673 0.7136000268597673 0.0 cell_activation GO:0001775 12133 656 35 2 7541 28 1 false 0.7136669125958102 0.7136669125958102 0.0 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 35 3 768 5 1 false 0.7188550635990447 0.7188550635990447 1.6461815804374103E-220 lymphocyte_activation GO:0046649 12133 403 35 2 475 2 1 false 0.7195469686876439 0.7195469686876439 3.3805466364584557E-87 mitochondrial_part GO:0044429 12133 557 35 2 7185 32 3 false 0.7217257332990867 0.7217257332990867 0.0 protein_ubiquitination GO:0016567 12133 548 35 6 578 6 1 false 0.7252625707518345 0.7252625707518345 7.913703273197485E-51 ATPase_activity,_coupled GO:0042623 12133 228 35 3 307 4 1 false 0.7264959265061783 0.7264959265061783 1.7947531856464704E-75 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 35 2 381 4 2 false 0.7287467416803275 0.7287467416803275 8.855041133991382E-114 cell_development GO:0048468 12133 1255 35 4 3306 12 4 false 0.7291431056618568 0.7291431056618568 0.0 positive_regulation_of_transferase_activity GO:0051347 12133 445 35 1 2275 6 3 false 0.7295290911115238 0.7295290911115238 0.0 protein_complex_binding GO:0032403 12133 306 35 1 6397 27 1 false 0.7345210025400492 0.7345210025400492 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 35 4 379 4 1 false 0.7347162184919973 0.7347162184919973 5.324332733169013E-43 organelle_fission GO:0048285 12133 351 35 1 2031 7 1 false 0.7356038663658698 0.7356038663658698 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 35 14 4972 25 3 false 0.7360612446987754 0.7360612446987754 0.0 enzyme_regulator_activity GO:0030234 12133 771 35 2 10257 34 3 false 0.7364300369506254 0.7364300369506254 0.0 U5_snRNP GO:0005682 12133 80 35 2 93 2 1 false 0.7386629266012024 0.7386629266012024 3.852654648545616E-16 somatic_recombination_of_immunoglobulin_gene_segments GO:0016447 12133 40 35 1 54 1 2 false 0.7407407407407403 0.7407407407407403 3.081310036937439E-13 NAD-dependent_histone_deacetylase_activity_(H3-K9_specific) GO:0046969 12133 13 35 2 15 2 2 false 0.7428571428571431 0.7428571428571431 0.009523809523809518 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 35 6 106 6 2 false 0.7429136491774406 0.7429136491774406 9.867686559172291E-9 protein_kinase_activity GO:0004672 12133 1014 35 3 1347 4 3 false 0.7431320512187449 0.7431320512187449 0.0 cell_cycle_arrest GO:0007050 12133 202 35 1 998 6 2 false 0.7435328181998802 0.7435328181998802 1.5077994882682823E-217 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 35 15 6094 31 2 false 0.7455186897460941 0.7455186897460941 0.0 neuron_projection_morphogenesis GO:0048812 12133 475 35 1 637 1 2 false 0.7456828885398858 0.7456828885398858 3.7535814082411355E-156 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 35 1 1279 5 3 false 0.7458204001275095 0.7458204001275095 9.116385096369177E-305 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 35 3 1399 9 3 false 0.7474448064482041 0.7474448064482041 0.0 single-organism_carbohydrate_metabolic_process GO:0044723 12133 385 35 1 515 1 1 false 0.7475728155339276 0.7475728155339276 1.0653300741927565E-125 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 35 1 639 2 3 false 0.748038912682166 0.748038912682166 1.399157780258238E-191 cation_channel_activity GO:0005261 12133 216 35 1 433 2 2 false 0.749422632794659 0.749422632794659 1.1777872542675005E-129 regulation_of_cellular_process GO:0050794 12133 6304 35 20 9757 33 2 false 0.7496152835596033 0.7496152835596033 0.0 DNA_topoisomerase_II_activity GO:0061505 12133 6 35 1 8 1 1 false 0.7500000000000001 0.7500000000000001 0.035714285714285705 metal_ion_transport GO:0030001 12133 455 35 1 606 1 1 false 0.7508250825082763 0.7508250825082763 4.665536224038032E-147 positive_regulation_of_kinase_activity GO:0033674 12133 438 35 1 1181 3 3 false 0.7513633091802383 0.7513633091802383 0.0 organelle_organization GO:0006996 12133 2031 35 7 7663 31 2 false 0.752390644399071 0.752390644399071 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 35 5 400 5 2 false 0.7525272191527608 0.7525272191527608 1.150456419433401E-36 regulation_of_MAP_kinase_activity GO:0043405 12133 268 35 1 533 2 3 false 0.7532762487837519 0.7532762487837519 1.0382438249699724E-159 heart_development GO:0007507 12133 343 35 1 2876 11 3 false 0.7532928089540297 0.7532928089540297 0.0 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 35 1 1112 3 4 false 0.7562550173939411 0.7562550173939411 1.302733E-318 Wnt_receptor_signaling_pathway GO:0016055 12133 260 35 1 1975 10 1 false 0.7570790985990608 0.7570790985990608 0.0 nuclear_envelope GO:0005635 12133 258 35 1 3962 21 3 false 0.7577423437266584 0.7577423437266584 0.0 regulation_of_cell_morphogenesis GO:0022604 12133 267 35 1 1647 8 3 false 0.7578688740484412 0.7578688740484412 3.9027101E-316 cell_surface GO:0009986 12133 396 35 1 9983 35 1 false 0.7580719284211584 0.7580719284211584 0.0 covalent_chromatin_modification GO:0016569 12133 312 35 2 458 3 1 false 0.7604489422941352 0.7604489422941352 7.826311589520491E-124 membrane-bounded_vesicle GO:0031988 12133 762 35 3 834 3 1 false 0.7624631202790539 0.7624631202790539 6.820230733401612E-106 transmembrane_transport GO:0055085 12133 728 35 2 7606 28 2 false 0.7636003003390585 0.7636003003390585 0.0 microtubule-based_process GO:0007017 12133 378 35 1 7541 28 1 false 0.763682101040214 0.763682101040214 0.0 lymphocyte_mediated_immunity GO:0002449 12133 139 35 1 182 1 1 false 0.7637362637362488 0.7637362637362488 8.778235670388515E-43 cell_migration GO:0016477 12133 734 35 4 785 4 1 false 0.7639663995293615 0.7639663995293615 1.8763224028220524E-81 biological_regulation GO:0065007 12133 6908 35 21 10446 34 1 false 0.7670013317967306 0.7670013317967306 0.0 regulation_of_inflammatory_response GO:0050727 12133 151 35 1 702 6 3 false 0.7675505013964941 0.7675505013964941 5.1007818439049374E-158 cellular_response_to_organic_substance GO:0071310 12133 1347 35 5 1979 8 2 false 0.7697422558383706 0.7697422558383706 0.0 regulation_of_intracellular_protein_transport GO:0033157 12133 160 35 1 847 7 3 false 0.7703898272303881 0.7703898272303881 1.5386851760422239E-177 cation_transmembrane_transporter_activity GO:0008324 12133 365 35 1 701 2 2 false 0.7706134094151502 0.7706134094151502 5.744660517109641E-210 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 35 2 5027 29 3 false 0.771348020051082 0.771348020051082 0.0 regulation_of_transport GO:0051049 12133 942 35 3 3017 12 2 false 0.7759192346523629 0.7759192346523629 0.0 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 35 1 2035 9 3 false 0.7771091045720074 0.7771091045720074 0.0 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 35 2 1350 6 4 false 0.7786424177823192 0.7786424177823192 0.0 cellular_developmental_process GO:0048869 12133 2267 35 7 7817 29 2 false 0.7796210514485984 0.7796210514485984 0.0 lymphocyte_homeostasis GO:0002260 12133 43 35 1 55 1 1 false 0.7818181818181777 0.7818181818181777 2.27930752242823E-12 MAP_kinase_activity GO:0004707 12133 277 35 1 520 2 2 false 0.7821031569585083 0.7821031569585083 2.5282679507054518E-155 regulation_of_protein_transport GO:0051223 12133 261 35 1 1665 9 3 false 0.7853041231297415 0.7853041231297415 3.65102727546E-313 T_cell_receptor_signaling_pathway GO:0050852 12133 88 35 1 112 1 1 false 0.7857142857143178 0.7857142857143178 5.828412725788921E-25 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 35 6 181 6 1 false 0.7865846866874773 0.7865846866874773 8.905994863592909E-13 enzyme_activator_activity GO:0008047 12133 321 35 1 1413 6 2 false 0.7876151308655506 0.7876151308655506 0.0 tight_junction_assembly GO:0070830 12133 31 35 1 58 2 2 false 0.7876588021778664 0.7876588021778664 3.809192954277456E-17 cytoskeletal_part GO:0044430 12133 1031 35 4 5573 28 2 false 0.7886891145834335 0.7886891145834335 0.0 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 35 3 2780 8 2 false 0.7887480897338366 0.7887480897338366 0.0 regulation_of_intracellular_transport GO:0032386 12133 276 35 1 1731 9 3 false 0.7913713951093851 0.7913713951093851 0.0 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 35 1 312 1 1 false 0.7916666666666485 0.7916666666666485 8.216510305576978E-69 regulation_of_mRNA_stability GO:0043488 12133 33 35 2 37 2 1 false 0.792792792792794 0.792792792792794 1.5141191611779804E-5 viral_genome_replication GO:0019079 12133 55 35 1 557 15 2 false 0.7941312210632505 0.7941312210632505 1.9020892479615726E-77 taxis GO:0042330 12133 488 35 1 1496 4 2 false 0.7942826819586009 0.7942826819586009 0.0 leukocyte_mediated_immunity GO:0002443 12133 182 35 1 445 3 1 false 0.7945288555858595 0.7945288555858595 4.746005199012963E-130 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 35 1 912 3 2 false 0.796324753875338 0.796324753875338 2.059888800891414E-267 positive_regulation_of_leukocyte_activation GO:0002696 12133 206 35 1 756 5 4 false 0.7972118133780473 0.7972118133780473 1.5163059036704027E-191 transcription_factor_complex GO:0005667 12133 266 35 1 3138 18 2 false 0.7978852170347236 0.7978852170347236 0.0 mitochondrial_matrix GO:0005759 12133 236 35 1 3218 21 2 false 0.7990441412773126 0.7990441412773126 0.0 spindle_assembly_checkpoint GO:0071173 12133 36 35 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 35 1 3785 19 2 false 0.8014392749628216 0.8014392749628216 0.0 positive_regulation_of_signal_transduction GO:0009967 12133 782 35 2 3650 13 5 false 0.8027104719696954 0.8027104719696954 0.0 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 35 1 361 4 1 false 0.8030227978829908 0.8030227978829908 4.560830022372086E-99 cellular_membrane_organization GO:0016044 12133 784 35 2 7541 28 2 false 0.8040427306430533 0.8040427306430533 0.0 positive_regulation_of_signaling GO:0023056 12133 817 35 2 4861 17 3 false 0.8062824887336064 0.8062824887336064 0.0 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 35 1 1088 5 3 false 0.807644625913126 0.807644625913126 1.7563474810306042E-279 regulation_of_catabolic_process GO:0009894 12133 554 35 2 5455 29 2 false 0.8091462318977486 0.8091462318977486 0.0 isotype_switching GO:0045190 12133 34 35 1 42 1 2 false 0.8095238095238179 0.8095238095238179 8.472408985887957E-9 cellular_cation_homeostasis GO:0030003 12133 289 35 1 513 2 2 false 0.8098196881091319 0.8098196881091319 6.525965777081911E-152 purine-containing_compound_metabolic_process GO:0072521 12133 1232 35 5 5323 28 5 false 0.8109172943154855 0.8109172943154855 0.0 regulation_of_lymphocyte_activation GO:0051249 12133 245 35 1 434 2 2 false 0.8109215525592754 0.8109215525592754 2.1869753110099554E-128 nucleoside_phosphate_binding GO:1901265 12133 1998 35 8 4407 21 2 false 0.8120332431208959 0.8120332431208959 0.0 positive_regulation_of_cell_communication GO:0010647 12133 820 35 2 4819 17 3 false 0.8122469637855944 0.8122469637855944 0.0 response_to_wounding GO:0009611 12133 905 35 3 2540 11 1 false 0.8123613417796434 0.8123613417796434 0.0 tissue_morphogenesis GO:0048729 12133 415 35 1 2931 11 3 false 0.8140931887471546 0.8140931887471546 0.0 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 35 1 3799 26 1 false 0.8150837883125777 0.8150837883125777 0.0 cation_binding GO:0043169 12133 2758 35 7 4448 13 1 false 0.815134431786547 0.815134431786547 0.0 ATP-dependent_helicase_activity GO:0008026 12133 98 35 1 228 3 2 false 0.8164840192954865 0.8164840192954865 4.1384935546953996E-67 cell_projection_morphogenesis GO:0048858 12133 541 35 1 946 2 3 false 0.816973723950766 0.816973723950766 1.1683643564827775E-279 cellular_protein_complex_disassembly GO:0043624 12133 149 35 6 154 6 1 false 0.8175954281708957 0.8175954281708957 1.4793035521715585E-9 generation_of_precursor_metabolites_and_energy GO:0006091 12133 364 35 1 7256 33 1 false 0.8177323421377586 0.8177323421377586 0.0 single_organism_signaling GO:0044700 12133 3878 35 12 8052 29 2 false 0.8205782326090322 0.8205782326090322 0.0 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 35 1 506 4 3 false 0.8224197439192596 0.8224197439192596 1.5079927652081954E-141 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 35 1 185 1 1 false 0.8270270270271043 0.8270270270271043 1.2806047113744547E-36 intracellular_signal_transduction GO:0035556 12133 1813 35 5 3547 12 1 false 0.8273761240883264 0.8273761240883264 0.0 rRNA_processing GO:0006364 12133 102 35 1 231 3 3 false 0.8276433268647536 0.8276433268647536 2.6685808966337758E-68 system_development GO:0048731 12133 2686 35 9 3304 12 2 false 0.8281744270985537 0.8281744270985537 0.0 protein_modification_process GO:0036211 12133 2370 35 12 3518 20 2 false 0.8282776130400475 0.8282776130400475 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 35 4 351 4 1 false 0.8290748849786549 0.8290748849786549 5.577217121688537E-28 regulation_of_cell_cycle_process GO:0010564 12133 382 35 2 1096 8 2 false 0.829687912541619 0.829687912541619 7.137372224746455E-307 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 35 1 415 4 3 false 0.8300398939988625 0.8300398939988625 9.462933237946419E-117 nuclear_chromosome_part GO:0044454 12133 244 35 1 2878 20 3 false 0.8310216586699937 0.8310216586699937 0.0 sarcomere GO:0030017 12133 129 35 1 155 1 2 false 0.8322580645161162 0.8322580645161162 4.189006503961452E-30 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 35 5 5657 28 2 false 0.8341346177308905 0.8341346177308905 0.0 transport GO:0006810 12133 2783 35 10 2833 10 1 false 0.8366466937081535 0.8366466937081535 1.147202604491021E-108 identical_protein_binding GO:0042802 12133 743 35 2 6397 27 1 false 0.8383790568341467 0.8383790568341467 0.0 protein_homodimerization_activity GO:0042803 12133 471 35 1 1035 3 2 false 0.838578044428357 0.838578044428357 7.159384282986134E-309 organophosphate_metabolic_process GO:0019637 12133 1549 35 5 7521 33 2 false 0.8393625342293475 0.8393625342293475 0.0 response_to_organic_substance GO:0010033 12133 1783 35 6 2369 9 1 false 0.8395678136371392 0.8395678136371392 0.0 cellular_metal_ion_homeostasis GO:0006875 12133 259 35 1 308 1 2 false 0.8409090909089498 0.8409090909089498 3.9623191237847456E-58 regulation_of_protein_phosphorylation GO:0001932 12133 787 35 3 1444 7 3 false 0.8410822099993309 0.8410822099993309 0.0 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 35 6 645 7 1 false 0.8413579038495537 0.8413579038495537 7.3138241320053254E-93 metal_ion_homeostasis GO:0055065 12133 278 35 1 330 1 1 false 0.8424242424241729 0.8424242424241729 6.131976736615521E-62 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 35 28 7976 32 2 false 0.8447497742194097 0.8447497742194097 0.0 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 35 3 2877 13 6 false 0.8450537705414239 0.8450537705414239 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 35 2 6358 20 2 false 0.8455590943191567 0.8455590943191567 0.0 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 35 1 766 2 2 false 0.8459018071985545 0.8459018071985545 4.217322594612318E-222 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 35 7 6129 32 3 false 0.8465897339409345 0.8465897339409345 0.0 MAPK_cascade GO:0000165 12133 502 35 2 806 4 1 false 0.8466638439643318 0.8466638439643318 3.7900857366173457E-231 endosome GO:0005768 12133 455 35 1 8213 33 2 false 0.8481060477228317 0.8481060477228317 0.0 double-stranded_DNA_binding GO:0003690 12133 109 35 1 179 2 1 false 0.8484087627894839 0.8484087627894839 1.5496409193142626E-51 somatic_recombination_of_immunoglobulin_genes_involved_in_immune_response GO:0002204 12133 34 35 1 40 1 2 false 0.8500000000000089 0.8500000000000089 2.6052657631605196E-7 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 35 1 217 2 2 false 0.8512544802866326 0.8512544802866326 2.2668758893633536E-62 mitochondrion GO:0005739 12133 1138 35 3 8213 33 2 false 0.8550668098433328 0.8550668098433328 0.0 erythrocyte_homeostasis GO:0034101 12133 95 35 1 111 1 1 false 0.8558558558558544 0.8558558558558544 1.225965890705918E-19 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 35 2 660 3 2 false 0.8559436140652248 0.8559436140652248 4.8010140095396714E-157 cation_homeostasis GO:0055080 12133 330 35 1 532 2 1 false 0.8562720360227958 0.8562720360227958 1.1320770482912473E-152 protein_dimerization_activity GO:0046983 12133 779 35 2 6397 27 1 false 0.8581746705536064 0.8581746705536064 0.0 membrane-bounded_organelle GO:0043227 12133 7284 35 28 7980 32 1 false 0.8583147348672282 0.8583147348672282 0.0 cellular_component_disassembly_involved_in_execution_phase_of_apoptosis GO:0006921 12133 80 35 1 372 8 2 false 0.8588684256429158 0.8588684256429158 1.5687432555814248E-83 metal_ion_binding GO:0046872 12133 2699 35 7 2758 7 1 false 0.8593853723950909 0.8593853723950909 2.6200760259069314E-123 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 35 1 3842 17 3 false 0.8601847249615648 0.8601847249615648 0.0 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 35 5 7451 33 1 false 0.8604225445773117 0.8604225445773117 0.0 protein_complex_assembly GO:0006461 12133 743 35 6 1214 12 3 false 0.8633339434134788 0.8633339434134788 0.0 macromolecular_complex_assembly GO:0065003 12133 973 35 7 1603 14 2 false 0.8633850405465225 0.8633850405465225 0.0 mitochondrial_inner_membrane GO:0005743 12133 241 35 1 382 2 2 false 0.8643690481097188 0.8643690481097188 1.3545216387089424E-108 striated_muscle_cell_development GO:0055002 12133 133 35 1 211 2 2 false 0.8644549763032303 0.8644549763032303 7.542852200614712E-60 peptidyl-amino_acid_modification GO:0018193 12133 623 35 2 2370 12 1 false 0.8647898018828117 0.8647898018828117 0.0 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 35 1 365 1 1 false 0.8657534246575868 0.8657534246575868 4.982755146780477E-62 cell_cycle_checkpoint GO:0000075 12133 202 35 2 217 2 1 false 0.8662314388120638 0.8662314388120638 1.925703524045096E-23 nuclear_chromosome GO:0000228 12133 278 35 1 2899 20 3 false 0.8677661175747626 0.8677661175747626 0.0 regulation_of_hydrolase_activity GO:0051336 12133 821 35 2 3094 12 2 false 0.8686625846563287 0.8686625846563287 0.0 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 35 1 129 3 1 false 0.8690715986082982 0.8690715986082982 2.169508265339551E-38 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 35 15 5532 31 4 false 0.8690945292009785 0.8690945292009785 0.0 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 35 3 614 3 1 false 0.8691326427752593 0.8691326427752593 4.862693095923331E-49 regulation_of_apoptotic_process GO:0042981 12133 1019 35 5 1381 8 2 false 0.869353936739814 0.869353936739814 0.0 cell_projection GO:0042995 12133 976 35 2 9983 35 1 false 0.8696147324927014 0.8696147324927014 0.0 axonogenesis GO:0007409 12133 421 35 1 483 1 2 false 0.8716356107660534 0.8716356107660534 7.423880338325494E-80 apical_junction_assembly GO:0043297 12133 37 35 1 58 2 1 false 0.8729582577132535 0.8729582577132535 2.991639077401756E-16 tissue_development GO:0009888 12133 1132 35 3 3099 12 1 false 0.873218582300856 0.873218582300856 0.0 DNA_integrity_checkpoint GO:0031570 12133 130 35 1 202 2 1 false 0.8740948721737103 0.8740948721737103 1.23666756413938E-56 maturation_of_SSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000462 12133 7 35 1 8 1 1 false 0.8749999999999999 0.8749999999999999 0.12499999999999997 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 35 1 129 3 1 false 0.875022889580666 0.875022889580666 2.1037655906323275E-38 chemotaxis GO:0006935 12133 488 35 1 2369 9 2 false 0.8750613585511486 0.8750613585511486 0.0 cell_proliferation GO:0008283 12133 1316 35 3 8052 29 1 false 0.875120474497761 0.875120474497761 0.0 mRNA_processing GO:0006397 12133 374 35 4 763 11 2 false 0.8752893176353669 0.8752893176353669 8.270510506831645E-229 regulation_of_leukocyte_activation GO:0002694 12133 278 35 1 948 6 3 false 0.8761961520960733 0.8761961520960733 2.7935655578419027E-248 organophosphate_catabolic_process GO:0046434 12133 1000 35 5 2495 17 2 false 0.8762064552613964 0.8762064552613964 0.0 lipid_binding GO:0008289 12133 571 35 1 8962 32 1 false 0.8788170806336175 0.8788170806336175 0.0 organ_development GO:0048513 12133 1929 35 6 3099 12 2 false 0.8789121031862467 0.8789121031862467 0.0 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 35 1 185 1 1 false 0.881081081081119 0.881081081081119 5.464989090238489E-29 protein_polyubiquitination GO:0000209 12133 163 35 1 548 6 1 false 0.8811478878838245 0.8811478878838245 3.681189236491621E-144 vesicle-mediated_transport GO:0016192 12133 895 35 2 2783 10 1 false 0.8819105558225286 0.8819105558225286 0.0 positive_regulation_of_cell_differentiation GO:0045597 12133 439 35 1 3709 17 4 false 0.8831036477422703 0.8831036477422703 0.0 ion_binding GO:0043167 12133 4448 35 13 8962 32 1 false 0.8848109078928722 0.8848109078928722 0.0 translation_initiation_factor_activity GO:0003743 12133 50 35 1 191 7 2 false 0.8852107077425589 0.8852107077425589 3.1223441687767467E-47 hemopoiesis GO:0030097 12133 462 35 2 491 2 1 false 0.8852487634564072 0.8852487634564072 1.8682876304369947E-47 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 35 1 929 6 2 false 0.8856331276339307 0.8856331276339307 1.7613668775256747E-246 cell_communication GO:0007154 12133 3962 35 12 7541 28 1 false 0.8883047528781687 0.8883047528781687 0.0 glucose_metabolic_process GO:0006006 12133 183 35 1 206 1 1 false 0.888349514563178 0.888349514563178 5.590923529140016E-31 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 35 2 129 3 1 false 0.8891944012085654 0.8891944012085654 2.104544859412626E-28 intrinsic_to_membrane GO:0031224 12133 2375 35 2 2995 3 1 false 0.8892774043792759 0.8892774043792759 0.0 ion_transport GO:0006811 12133 833 35 2 2323 9 1 false 0.8896331017016932 0.8896331017016932 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 35 2 214 2 1 false 0.8907463472423881 0.8907463472423881 7.108512362452622E-20 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 35 1 1079 4 3 false 0.8928329473106157 0.8928329473106157 5.98264E-319 induction_of_programmed_cell_death GO:0012502 12133 157 35 1 368 4 1 false 0.8932363191615602 0.8932363191615602 2.1106051638808005E-108 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 35 5 2517 17 2 false 0.8936494863993372 0.8936494863993372 0.0 cell_morphogenesis GO:0000902 12133 766 35 2 810 2 1 false 0.8942452959754951 0.8942452959754951 9.285456073507826E-74 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 35 4 2528 13 3 false 0.8949137954558695 0.8949137954558695 0.0 induction_of_apoptosis GO:0006917 12133 156 35 1 363 4 2 false 0.8955768725570932 0.8955768725570932 4.583372865169243E-107 response_to_oxygen-containing_compound GO:1901700 12133 864 35 2 2369 9 1 false 0.8964998616155051 0.8964998616155051 0.0 adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002460 12133 156 35 1 174 1 1 false 0.8965517241379637 0.8965517241379637 7.444259624063543E-25 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 35 5 1218 5 2 false 0.8975669803581972 0.8975669803581972 3.12960829510125E-54 cell_part_morphogenesis GO:0032990 12133 551 35 1 810 2 1 false 0.898026827816791 0.898026827816791 1.1709501739830369E-219 endopeptidase_activity GO:0004175 12133 470 35 2 586 3 1 false 0.898451276776388 0.898451276776388 5.73935751356398E-126 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 35 1 4239 20 3 false 0.8989585487048306 0.8989585487048306 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 35 14 3611 21 3 false 0.9008402930138086 0.9008402930138086 0.0 protein_kinase_binding GO:0019901 12133 341 35 4 384 5 1 false 0.9015438159041947 0.9015438159041947 5.20098898434574E-58 zinc_ion_binding GO:0008270 12133 1314 35 1 1457 1 1 false 0.9018531228546426 0.9018531228546426 2.194714234876188E-202 chemical_homeostasis GO:0048878 12133 677 35 2 990 4 1 false 0.9039996154767402 0.9039996154767402 1.9931274413677286E-267 regulation_of_organelle_organization GO:0033043 12133 519 35 1 2487 10 2 false 0.9041891386479559 0.9041891386479559 0.0 negative_regulation_of_cell_proliferation GO:0008285 12133 455 35 1 2949 14 3 false 0.9047970573206607 0.9047970573206607 0.0 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 35 1 1211 5 2 false 0.9050268308882485 0.9050268308882485 0.0 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 35 4 207 4 1 false 0.906168381823938 0.906168381823938 3.3148479610294504E-10 nucleoside-triphosphatase_activity GO:0017111 12133 1059 35 5 1080 5 1 false 0.9063189430130167 0.9063189430130167 1.2343281293318376E-44 carbohydrate_metabolic_process GO:0005975 12133 515 35 1 7453 33 2 false 0.9063486522887969 0.9063486522887969 0.0 kinase_activity GO:0016301 12133 1174 35 3 1546 5 2 false 0.9064646706152371 0.9064646706152371 0.0 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 35 1 129 3 1 false 0.9069853277788049 0.9069853277788049 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 35 1 129 3 1 false 0.9069853277788049 0.9069853277788049 3.3394798770258706E-38 nuclear_transport GO:0051169 12133 331 35 1 1148 7 1 false 0.9082242612754097 0.9082242612754097 1.3196682196913852E-298 regulatory_region_DNA_binding GO:0000975 12133 1169 35 4 2091 10 2 false 0.908674930556767 0.908674930556767 0.0 protein_import_into_nucleus GO:0006606 12133 200 35 1 690 7 5 false 0.9100517299657798 0.9100517299657798 1.1794689955817937E-179 biological_adhesion GO:0022610 12133 714 35 1 10446 34 1 false 0.9102869328227543 0.9102869328227543 0.0 epithelium_development GO:0060429 12133 627 35 1 1132 3 1 false 0.9115083232271376 0.9115083232271376 0.0 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 35 5 672 12 1 false 0.9115974833223471 0.9115974833223471 6.935915883902889E-199 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 35 1 129 3 1 false 0.9117148873832577 0.9117148873832577 4.0186961232005657E-38 neurological_system_process GO:0050877 12133 894 35 1 1272 2 1 false 0.9118544304736038 0.9118544304736038 0.0 regulation_of_JNK_cascade GO:0046328 12133 126 35 1 179 2 2 false 0.9135019772769651 0.9135019772769651 9.08597934181437E-47 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 35 5 1072 5 2 false 0.9143124268728643 0.9143124268728643 3.811291228230986E-41 cytoskeletal_protein_binding GO:0008092 12133 556 35 1 6397 27 1 false 0.9145881352478203 0.9145881352478203 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 35 1 165 1 2 false 0.9151515151515951 0.9151515151515951 1.3866478491946915E-20 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 35 5 2643 17 2 false 0.9173573869653942 0.9173573869653942 0.0 T_cell_activation GO:0042110 12133 288 35 1 403 2 1 false 0.9190770712196987 0.9190770712196987 5.060432780788644E-104 mitosis GO:0007067 12133 326 35 1 953 6 2 false 0.9195591980899633 0.9195591980899633 4.8424843971573165E-265 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 35 8 2805 8 1 false 0.9201262054482057 0.9201262054482057 1.0460685646312495E-69 purine_ribonucleotide_binding GO:0032555 12133 1641 35 7 1660 7 2 false 0.9224432799832952 0.9224432799832952 8.870449707822982E-45 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 35 5 378 5 1 false 0.9227177891663332 0.9227177891663332 2.5686196448553377E-13 protein_phosphorylation GO:0006468 12133 1195 35 4 2577 13 2 false 0.9229952368596422 0.9229952368596422 0.0 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 35 2 78 2 1 false 0.9240759240759076 0.9240759240759076 1.3144749986854762E-5 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 35 1 309 3 2 false 0.9248105709789438 0.9248105709789438 7.558729588417702E-91 purine-containing_compound_catabolic_process GO:0072523 12133 959 35 5 1651 12 6 false 0.9256107715391515 0.9256107715391515 0.0 somatic_diversification_of_immune_receptors_via_germline_recombination_within_a_single_locus GO:0002562 12133 50 35 1 54 1 2 false 0.9259259259259376 0.9259259259259376 3.162045337406044E-6 cation_transport GO:0006812 12133 606 35 1 833 2 1 false 0.9259771216182419 0.9259771216182419 4.047492354513465E-211 cellular_component_morphogenesis GO:0032989 12133 810 35 2 5068 25 4 false 0.9264724634329576 0.9264724634329576 0.0 programmed_cell_death GO:0012501 12133 1385 35 9 1525 11 1 false 0.9277808454515528 0.9277808454515528 2.142172117700311E-202 nuclear_division GO:0000280 12133 326 35 1 351 1 1 false 0.9287749287750802 0.9287749287750802 8.671827254018066E-39 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 35 1 129 3 1 false 0.9290308551547333 0.9290308551547333 1.1512773005265922E-37 glycosyl_compound_catabolic_process GO:1901658 12133 956 35 5 2175 17 2 false 0.930322271896381 0.930322271896381 0.0 myofibril GO:0030016 12133 148 35 1 159 1 1 false 0.930817610062944 0.930817610062944 3.462863266418168E-17 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 35 3 5183 22 2 false 0.9351910220321152 0.9351910220321152 0.0 regulation_of_programmed_cell_death GO:0043067 12133 1031 35 5 1410 9 2 false 0.935555057973894 0.935555057973894 0.0 neuron_development GO:0048666 12133 654 35 1 1313 4 2 false 0.9368304230130314 0.9368304230130314 0.0 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 35 5 7461 33 2 false 0.9368513405599759 0.9368513405599759 0.0 endomembrane_system GO:0012505 12133 1211 35 2 9983 35 1 false 0.937203368565269 0.937203368565269 0.0 cell_adhesion GO:0007155 12133 712 35 1 7542 28 2 false 0.9380727175877325 0.9380727175877325 0.0 organ_morphogenesis GO:0009887 12133 649 35 1 2908 11 3 false 0.9381736273095872 0.9381736273095872 0.0 generation_of_neurons GO:0048699 12133 883 35 1 940 1 1 false 0.9393617021272437 0.9393617021272437 7.799501535546468E-93 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 35 14 4395 27 3 false 0.9403088088641701 0.9403088088641701 0.0 chromosomal_part GO:0044427 12133 512 35 1 5337 28 2 false 0.9410712335218915 0.9410712335218915 0.0 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 35 13 4544 29 3 false 0.9411283735016595 0.9411283735016595 0.0 regulation_of_gene_expression GO:0010468 12133 2935 35 16 4361 29 2 false 0.9418055890508582 0.9418055890508582 0.0 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 35 1 7293 28 3 false 0.943978187029817 0.943978187029817 0.0 DNA_binding GO:0003677 12133 2091 35 10 2849 17 1 false 0.9440837144169602 0.9440837144169602 0.0 ribonucleoside_metabolic_process GO:0009119 12133 1071 35 5 1083 5 1 false 0.9457144270360025 0.9457144270360025 1.9559437642804265E-28 positive_regulation_of_cell_proliferation GO:0008284 12133 558 35 1 3155 15 3 false 0.9464237049772485 0.9464237049772485 0.0 response_to_unfolded_protein GO:0006986 12133 126 35 1 133 1 1 false 0.9473684210526476 0.9473684210526476 8.038720251232349E-12 hexose_metabolic_process GO:0019318 12133 206 35 1 217 1 1 false 0.9493087557602818 0.9493087557602818 1.0279992997812003E-18 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 35 3 4582 22 3 false 0.9510858051393674 0.9510858051393674 0.0 regulation_of_cellular_catabolic_process GO:0031329 12133 494 35 1 5000 29 3 false 0.951478679144398 0.951478679144398 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 35 5 1014 5 1 false 0.9515596164819137 0.9515596164819137 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 35 5 1014 5 1 false 0.9515596164819137 0.9515596164819137 3.301546202575714E-24 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 35 3 5558 29 3 false 0.9517156580019662 0.9517156580019662 0.0 integral_to_membrane GO:0016021 12133 2318 35 2 2375 2 1 false 0.952566133110128 0.952566133110128 3.0839384482043954E-116 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 35 5 1587 12 3 false 0.9531204000517588 0.9531204000517588 0.0 cytoskeleton_organization GO:0007010 12133 719 35 1 2031 7 1 false 0.9533233368733965 0.9533233368733965 0.0 membrane_organization GO:0061024 12133 787 35 2 3745 21 1 false 0.9539563550085597 0.9539563550085597 0.0 cytoskeleton GO:0005856 12133 1430 35 5 3226 18 1 false 0.9541461418636091 0.9541461418636091 0.0 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 35 3 4456 22 4 false 0.9543664029419285 0.9543664029419285 0.0 cytoplasmic_vesicle GO:0031410 12133 764 35 1 8540 33 3 false 0.954897418562686 0.954897418562686 0.0 nucleoplasm_part GO:0044451 12133 805 35 3 2767 20 2 false 0.958013486454529 0.958013486454529 0.0 cell_projection_organization GO:0030030 12133 744 35 1 7663 31 2 false 0.9581073420882102 0.9581073420882102 0.0 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 35 3 149 3 1 false 0.9600036277888687 0.9600036277888687 9.06947215672054E-5 system_process GO:0003008 12133 1272 35 2 4095 14 1 false 0.9602279943955625 0.9602279943955625 0.0 transcription_coactivator_activity GO:0003713 12133 264 35 1 478 4 2 false 0.9604483273163545 0.9604483273163545 4.798051856605128E-142 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 35 4 2849 17 1 false 0.9616384231403297 0.9616384231403297 0.0 chordate_embryonic_development GO:0043009 12133 471 35 3 477 3 1 false 0.9626594232531492 0.9626594232531492 6.308586670641318E-14 transcription,_DNA-dependent GO:0006351 12133 2643 35 13 4063 26 3 false 0.9632243258507542 0.9632243258507542 0.0 nucleoside_catabolic_process GO:0009164 12133 952 35 5 1516 12 5 false 0.9634247210455963 0.9634247210455963 0.0 neuron_differentiation GO:0030182 12133 812 35 1 2154 7 2 false 0.9637774442693883 0.9637774442693883 0.0 mononuclear_cell_proliferation GO:0032943 12133 161 35 1 167 1 1 false 0.9640718562873847 0.9640718562873847 3.634774947475864E-11 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 35 3 3972 22 4 false 0.9640869744826059 0.9640869744826059 0.0 transferase_activity GO:0016740 12133 1779 35 3 4901 16 1 false 0.9641392525511574 0.9641392525511574 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 35 13 3220 20 4 false 0.9643006997441612 0.9643006997441612 0.0 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 35 3 5151 29 4 false 0.9652492144616476 0.9652492144616476 0.0 protein_deacetylation GO:0006476 12133 57 35 2 58 2 1 false 0.9655172413793084 0.9655172413793084 0.017241379310345032 striated_muscle_tissue_development GO:0014706 12133 285 35 1 295 1 1 false 0.9661016949152815 0.9661016949152815 8.482306621073292E-19 purine_nucleoside_binding GO:0001883 12133 1631 35 7 1639 7 1 false 0.9662681978908815 0.9662681978908815 7.876250956196666E-22 immunoglobulin_mediated_immune_response GO:0016064 12133 89 35 1 92 1 1 false 0.967391304347824 0.967391304347824 7.963051441312322E-6 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 35 1 81 2 2 false 0.9675925925926091 0.9675925925926091 1.2278945146862784E-16 neurogenesis GO:0022008 12133 940 35 1 2425 7 2 false 0.9678843495769716 0.9678843495769716 0.0 Golgi_apparatus GO:0005794 12133 828 35 1 8213 33 2 false 0.970223941284901 0.970223941284901 0.0 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 35 5 1007 5 2 false 0.970503501092729 0.970503501092729 7.008686204750717E-16 response_to_DNA_damage_stimulus GO:0006974 12133 570 35 1 1124 5 1 false 0.9711778945715079 0.9711778945715079 0.0 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 35 3 3847 25 4 false 0.9715527535299128 0.9715527535299128 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 35 3 4103 26 3 false 0.9715612936190477 0.9715612936190477 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 35 1 1014 3 1 false 0.9729736038329457 0.9729736038329457 1.8231541307779663E-268 endoplasmic_reticulum GO:0005783 12133 854 35 1 8213 33 2 false 0.9735021161012132 0.9735021161012132 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 35 8 7256 33 1 false 0.9735374899640042 0.9735374899640042 0.0 chromosome GO:0005694 12133 592 35 1 3226 18 1 false 0.9742677769547294 0.9742677769547294 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 35 7 1635 7 2 false 0.9745467802940866 0.9745467802940866 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 35 7 1639 7 1 false 0.9746083294161478 0.9746083294161478 3.7483303336303164E-17 transcription_cofactor_activity GO:0003712 12133 456 35 4 482 5 2 false 0.974667571684994 0.974667571684994 1.3948726648763881E-43 GTP_metabolic_process GO:0046039 12133 625 35 1 1193 5 3 false 0.9757608101069712 0.9757608101069712 0.0 viral_reproduction GO:0016032 12133 633 35 15 634 15 1 false 0.9763406940065618 0.9763406940065618 0.0015772870662463625 molecular_transducer_activity GO:0060089 12133 1070 35 1 10257 34 1 false 0.9765338772292256 0.9765338772292256 0.0 single-organism_metabolic_process GO:0044710 12133 2877 35 7 8027 33 1 false 0.9776753936207502 0.9776753936207502 0.0 peptide_binding GO:0042277 12133 178 35 1 182 1 1 false 0.9780219780219295 0.9780219780219295 2.2611831618281403E-8 response_to_other_organism GO:0051707 12133 475 35 3 1194 16 2 false 0.981486447292356 0.981486447292356 0.0 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 35 5 1085 5 1 false 0.9816686606152377 0.9816686606152377 1.7413918354446858E-11 cellular_protein_modification_process GO:0006464 12133 2370 35 12 3038 20 2 false 0.9818118193748103 0.9818118193748103 0.0 DNA_duplex_unwinding GO:0032508 12133 54 35 1 55 1 1 false 0.9818181818181652 0.9818181818181652 0.018181818181817966 response_to_external_stimulus GO:0009605 12133 1046 35 1 5200 18 1 false 0.9825774836077718 0.9825774836077718 0.0 organelle_membrane GO:0031090 12133 1619 35 2 9319 32 3 false 0.9829146758017507 0.9829146758017507 0.0 interphase GO:0051325 12133 233 35 2 253 3 1 false 0.982974182696793 0.982974182696793 4.555981744751407E-30 epithelium_migration GO:0090132 12133 130 35 2 131 2 1 false 0.9847328244274453 0.9847328244274453 0.007633587786259341 receptor_binding GO:0005102 12133 918 35 1 6397 27 1 false 0.9848793992830865 0.9848793992830865 0.0 protein_localization_to_nucleus GO:0034504 12133 233 35 1 516 7 1 false 0.9855712000745093 0.9855712000745093 1.4955266190313754E-153 protein_targeting_to_nucleus GO:0044744 12133 200 35 1 443 7 1 false 0.9856373096113723 0.9856373096113723 9.352491047681514E-132 GTPase_activity GO:0003924 12133 612 35 1 1061 5 2 false 0.9866017251196354 0.9866017251196354 4.702100395E-313 signal_transducer_activity GO:0004871 12133 1070 35 1 3547 12 2 false 0.9866562524695012 0.9866562524695012 0.0 nucleocytoplasmic_transport GO:0006913 12133 327 35 1 331 1 1 false 0.9879154078549209 0.9879154078549209 2.036102168267257E-9 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 35 2 1546 12 3 false 0.9881874498124923 0.9881874498124923 0.0 extracellular_space GO:0005615 12133 574 35 1 740 3 1 false 0.9888697899526836 0.9888697899526836 2.3774559423833748E-170 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 35 4 1225 6 2 false 0.9898876664638337 0.9898876664638337 5.928244845001387E-155 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 35 1 1053 5 1 false 0.9901676761910536 0.9901676761910536 1.6418245301060377E-306 'de_novo'_posttranslational_protein_folding GO:0051084 12133 46 35 1 51 2 1 false 0.9921568627450973 0.9921568627450973 4.2570219577192243E-7 nucleotide_metabolic_process GO:0009117 12133 1317 35 5 1319 5 1 false 0.9924300034164193 0.9924300034164193 1.1504554077729292E-6 plasma_membrane_part GO:0044459 12133 1329 35 1 10213 35 3 false 0.9924640422235009 0.9924640422235009 0.0 GTP_catabolic_process GO:0006184 12133 614 35 1 957 5 4 false 0.994195848452219 0.994195848452219 2.3934835856107606E-270 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 35 1 956 5 2 false 0.9944996427718976 0.9944996427718976 3.936677708897206E-269 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 35 1 803 4 1 false 0.9947741937784299 0.9947741937784299 1.0286714317927864E-202 pyrophosphatase_activity GO:0016462 12133 1080 35 5 1081 5 1 false 0.995374653099011 0.995374653099011 9.250693802031629E-4 transition_metal_ion_binding GO:0046914 12133 1457 35 1 2699 7 1 false 0.9956703099769245 0.9956703099769245 0.0 protein_complex GO:0043234 12133 2976 35 18 3462 27 1 false 0.9975756564731109 0.9975756564731109 0.0 apoptotic_process GO:0006915 12133 1373 35 8 1385 9 1 false 0.9976033553269569 0.9976033553269569 1.0085392941984968E-29 cell_periphery GO:0071944 12133 2667 35 3 9983 35 1 false 0.9982733567206488 0.9982733567206488 0.0 nervous_system_development GO:0007399 12133 1371 35 1 2686 9 1 false 0.998406729573284 0.998406729573284 0.0 membrane_part GO:0044425 12133 2995 35 3 10701 35 2 false 0.9989476240868761 0.9989476240868761 0.0 plasma_membrane GO:0005886 12133 2594 35 2 10252 35 3 false 0.999534359807361 0.999534359807361 0.0 membrane GO:0016020 12133 4398 35 5 10701 35 1 false 0.9998681490225877 0.9998681490225877 0.0 GO:0000000 12133 11221 35 35 0 0 0 true 1.0 1.0 1.0 RNA_ligase_(ATP)_activity GO:0003972 12133 1 35 1 1 1 1 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 35 1 307 1 1 true 1.0 1.0 1.0 cullin_deneddylation GO:0010388 12133 9 35 1 9 1 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 35 2 304 2 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 35 2 147 2 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 35 4 1169 4 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 35 9 417 9 1 true 1.0 1.0 1.0