ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min translational_elongation GO:0006414 12133 121 19 11 3388 15 2 false 9.27704134476635E-14 9.27704134476635E-14 5.332026529203484E-226 ribosomal_subunit GO:0044391 12133 132 19 10 7199 18 4 false 1.1776953161165233E-13 1.1776953161165233E-13 2.5906239763169356E-285 translational_initiation GO:0006413 12133 160 19 10 7667 18 2 false 4.4821917595201E-13 4.4821917595201E-13 0.0 multi-organism_cellular_process GO:0044764 12133 634 19 13 9702 18 2 false 2.2252231250247438E-12 2.2252231250247438E-12 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 19 14 6457 17 3 false 7.79286313095615E-12 7.79286313095615E-12 0.0 ribosome GO:0005840 12133 210 19 10 6755 17 3 false 1.0968867283953602E-11 1.0968867283953602E-11 0.0 cytosolic_part GO:0044445 12133 178 19 10 5117 17 2 false 3.181726339884425E-11 3.181726339884425E-11 0.0 viral_transcription GO:0019083 12133 145 19 10 2964 14 3 false 4.902290147632469E-11 4.902290147632469E-11 1.0927707330622845E-250 macromolecule_catabolic_process GO:0009057 12133 820 19 14 6846 17 2 false 5.4347268717069946E-11 5.4347268717069946E-11 0.0 cellular_process_involved_in_reproduction GO:0048610 12133 469 19 11 9699 18 2 false 7.050496075956318E-11 7.050496075956318E-11 0.0 ribonucleoprotein_complex GO:0030529 12133 569 19 12 9264 19 2 false 8.72543993541958E-11 8.72543993541958E-11 0.0 catabolic_process GO:0009056 12133 2164 19 17 8027 17 1 false 2.0043222591435838E-10 2.0043222591435838E-10 0.0 cellular_catabolic_process GO:0044248 12133 1972 19 17 7289 17 2 false 2.1190265268772504E-10 2.1190265268772504E-10 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 19 17 7502 17 2 false 2.601617251167525E-10 2.601617251167525E-10 0.0 structural_molecule_activity GO:0005198 12133 526 19 11 10257 19 1 false 3.026311398169709E-10 3.026311398169709E-10 0.0 multi-organism_process GO:0051704 12133 1180 19 14 10446 19 1 false 3.4490763323772677E-10 3.4490763323772677E-10 0.0 cellular_component_disassembly GO:0022411 12133 351 19 10 7663 17 2 false 5.232448247275655E-10 5.232448247275655E-10 0.0 RNA_catabolic_process GO:0006401 12133 203 19 10 4368 17 3 false 5.531025399042012E-10 5.531025399042012E-10 0.0 translation GO:0006412 12133 457 19 11 5433 17 3 false 1.0324816609547263E-8 1.0324816609547263E-8 0.0 reproductive_process GO:0022414 12133 1275 19 13 10446 19 2 false 1.680184970301412E-8 1.680184970301412E-8 0.0 protein_targeting_to_ER GO:0045047 12133 104 19 10 721 11 3 false 2.5708388764826777E-8 2.5708388764826777E-8 1.514347826459292E-128 reproduction GO:0000003 12133 1345 19 13 10446 19 1 false 3.237574592030706E-8 3.237574592030706E-8 0.0 translational_termination GO:0006415 12133 92 19 10 513 11 2 false 2.121424513663077E-7 2.121424513663077E-7 3.4634519853301643E-104 macromolecular_complex GO:0032991 12133 3462 19 17 10701 19 1 false 3.75468169352411E-7 3.75468169352411E-7 0.0 protein_targeting GO:0006605 12133 443 19 11 2378 13 2 false 4.581211282502931E-7 4.581211282502931E-7 0.0 macromolecular_complex_disassembly GO:0032984 12133 199 19 10 1380 13 2 false 6.109421486672061E-7 6.109421486672061E-7 1.9082717261040364E-246 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 19 10 1239 12 2 false 7.822272334457606E-7 7.822272334457606E-7 4.427655683668096E-244 protein_complex_disassembly GO:0043241 12133 154 19 10 1031 13 2 false 8.122627861650437E-7 8.122627861650437E-7 4.7545827865276796E-188 mRNA_metabolic_process GO:0016071 12133 573 19 11 3294 15 1 false 2.8130269931812773E-6 2.8130269931812773E-6 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 19 13 5462 17 2 false 4.006518223818089E-6 4.006518223818089E-6 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 19 13 5528 17 2 false 4.161374376136301E-6 4.161374376136301E-6 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 19 13 5392 17 2 false 4.540849025625124E-6 4.540849025625124E-6 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 19 13 5388 17 2 false 4.853189910972187E-6 4.853189910972187E-6 0.0 cytosolic_ribosome GO:0022626 12133 92 19 10 296 10 2 false 5.90967601820618E-6 5.90967601820618E-6 4.2784789004852985E-79 cellular_localization GO:0051641 12133 1845 19 13 7707 17 2 false 7.210327594573932E-6 7.210327594573932E-6 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 19 10 516 12 1 false 1.0446673837318537E-5 1.0446673837318537E-5 8.917305549619806E-119 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 19 13 4878 17 5 false 1.1950613877046478E-5 1.1950613877046478E-5 0.0 cytosol GO:0005829 12133 2226 19 16 5117 17 1 false 1.6063072638792444E-5 1.6063072638792444E-5 0.0 structural_constituent_of_ribosome GO:0003735 12133 152 19 10 526 11 1 false 2.6975603159916874E-5 2.6975603159916874E-5 1.18011379183299E-136 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 19 16 10446 19 1 false 2.964792896378147E-5 2.964792896378147E-5 0.0 establishment_of_localization GO:0051234 12133 2833 19 14 10446 19 2 false 3.108292114544832E-5 3.108292114544832E-5 0.0 protein_metabolic_process GO:0019538 12133 3431 19 16 7395 17 2 false 4.341248195458257E-5 4.341248195458257E-5 0.0 mRNA_catabolic_process GO:0006402 12133 181 19 10 592 11 2 false 4.822587408647449E-5 4.822587408647449E-5 1.4563864024176219E-157 localization GO:0051179 12133 3467 19 15 10446 19 1 false 5.641871667477899E-5 5.641871667477899E-5 0.0 viral_genome_expression GO:0019080 12133 153 19 10 557 12 2 false 7.536342874944388E-5 7.536342874944388E-5 1.6461772406083414E-141 protein_targeting_to_membrane GO:0006612 12133 145 19 10 443 11 1 false 8.972241891485836E-5 8.972241891485836E-5 5.648405296311656E-121 macromolecular_complex_subunit_organization GO:0043933 12133 1256 19 13 3745 16 1 false 1.2058985618357919E-4 1.2058985618357919E-4 0.0 single-organism_transport GO:0044765 12133 2323 19 13 8134 18 2 false 1.5273582998319207E-4 1.5273582998319207E-4 0.0 viral_infectious_cycle GO:0019058 12133 213 19 11 557 12 1 false 1.7226151407651093E-4 1.7226151407651093E-4 3.455075709157513E-160 cellular_macromolecule_localization GO:0070727 12133 918 19 12 2206 13 2 false 2.0797695184750036E-4 2.0797695184750036E-4 0.0 cellular_protein_metabolic_process GO:0044267 12133 3038 19 16 5899 17 2 false 2.1093844291117977E-4 2.1093844291117977E-4 0.0 multi-organism_reproductive_process GO:0044703 12133 707 19 13 1275 13 1 false 4.4594085410634736E-4 4.4594085410634736E-4 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 19 10 220 10 2 false 4.8506363726857806E-4 4.8506363726857806E-4 1.3850176335002185E-65 ligase_activity GO:0016874 12133 504 19 5 4901 8 1 false 4.85088586383058E-4 4.85088586383058E-4 0.0 RNA_binding GO:0003723 12133 763 19 8 2849 10 1 false 6.76958372668782E-4 6.76958372668782E-4 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 19 17 8027 17 1 false 7.127682747118303E-4 7.127682747118303E-4 0.0 intracellular_transport GO:0046907 12133 1148 19 12 2815 14 2 false 7.304525670809889E-4 7.304525670809889E-4 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 19 17 7341 17 5 false 8.324668408494612E-4 8.324668408494612E-4 0.0 regulation_of_ligase_activity GO:0051340 12133 98 19 3 2061 5 2 false 9.729587718131064E-4 9.729587718131064E-4 1.6310105681359867E-170 protein_localization_to_organelle GO:0033365 12133 516 19 12 914 12 1 false 9.907594959568905E-4 9.907594959568905E-4 5.634955900168089E-271 intracellular_protein_transport GO:0006886 12133 658 19 11 1672 13 3 false 0.0010763280242800702 0.0010763280242800702 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 19 17 7451 17 1 false 0.001318669250686897 0.001318669250686897 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 19 17 7256 17 1 false 0.0014034433488587597 0.0014034433488587597 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 19 17 7256 17 1 false 0.0014377423304761396 0.0014377423304761396 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 19 5 2370 5 1 false 0.0014761874524005028 0.0014761874524005028 0.0 positive_regulation_of_ligase_activity GO:0051351 12133 84 19 3 1424 5 3 false 0.0018182476739122449 0.0018182476739122449 5.130084211911676E-138 negative_regulation_of_RNA_splicing GO:0033119 12133 15 19 2 1037 5 3 false 0.0019060255523795197 0.0019060255523795197 8.39457188486895E-34 biosynthetic_process GO:0009058 12133 4179 19 15 8027 17 1 false 0.0019833848399950266 0.0019833848399950266 0.0 cytoplasmic_part GO:0044444 12133 5117 19 17 9083 19 2 false 0.002161712033053181 0.002161712033053181 0.0 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 19 17 7275 17 2 false 0.0021617782635203124 0.0021617782635203124 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 19 2 3208 6 2 false 0.002314584509738753 0.002314584509738753 7.591030632914061E-95 organelle_part GO:0044422 12133 5401 19 16 10701 19 2 false 0.0024897148566298305 0.0024897148566298305 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 19 2 1199 3 2 false 0.0025817431698325513 0.0025817431698325513 9.194442294553035E-70 macromolecule_biosynthetic_process GO:0009059 12133 3475 19 15 6537 17 2 false 0.0026010757133681068 0.0026010757133681068 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 19 13 8962 15 1 false 0.0026831357167396534 0.0026831357167396534 0.0 gene_expression GO:0010467 12133 3708 19 16 6052 17 1 false 0.002808899810824315 0.002808899810824315 0.0 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 19 2 705 2 3 false 0.0029859767891684606 0.0029859767891684606 4.9570646354646075E-65 organic_cyclic_compound_binding GO:0097159 12133 4407 19 13 8962 15 1 false 0.00303880843751333 0.00303880843751333 0.0 negative_regulation_of_ligase_activity GO:0051352 12133 71 19 3 1003 5 3 false 0.003070438692791069 0.003070438692791069 8.698138776450475E-111 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 19 3 1056 5 3 false 0.003228797341859606 0.003228797341859606 4.764817151311381E-118 pore_complex GO:0046930 12133 84 19 2 5051 6 3 false 0.003925576006413398 0.003925576006413398 5.4712090537168384E-185 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 19 15 6146 17 3 false 0.004165943741614328 0.004165943741614328 0.0 cellular_protein_localization GO:0034613 12133 914 19 12 1438 12 2 false 0.004233905124839387 0.004233905124839387 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 19 15 7470 17 2 false 0.0043891920735990185 0.0043891920735990185 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 19 15 6846 17 2 false 0.0045425639522025 0.0045425639522025 0.0 cellular_biosynthetic_process GO:0044249 12133 4077 19 15 7290 17 2 false 0.00502344159306487 0.00502344159306487 0.0 sperm_entry GO:0035037 12133 1 19 1 2708 14 4 false 0.005169867060565125 0.005169867060565125 3.692762186116122E-4 regulation_of_RNA_splicing GO:0043484 12133 52 19 2 3151 7 3 false 0.0053207985497117985 0.0053207985497117985 1.4828410310444421E-114 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 19 3 1097 4 3 false 0.0058209995778429864 0.0058209995778429864 8.208279871491876E-172 cytoplasm GO:0005737 12133 6938 19 19 9083 19 1 false 0.005950628896476796 0.005950628896476796 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 19 17 7569 17 2 false 0.00616505805213913 0.00616505805213913 0.0 establishment_of_protein_localization GO:0045184 12133 1153 19 11 3010 15 2 false 0.0062720605103684 0.0062720605103684 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 19 13 7980 18 1 false 0.006347844920037731 0.006347844920037731 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 19 13 7958 18 2 false 0.006526757228595088 0.006526757228595088 0.0 intracellular_receptor_signaling_pathway GO:0030522 12133 217 19 3 3547 7 1 false 0.00657748747702391 0.00657748747702391 0.0 multi-organism_transport GO:0044766 12133 29 19 2 3441 15 2 false 0.006729040971593426 0.006729040971593426 2.716860412473803E-72 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 19 3 759 4 3 false 0.006931424216224925 0.006931424216224925 1.1458874617943115E-123 proteasome_complex GO:0000502 12133 62 19 2 9248 19 2 false 0.007027143188543303 0.007027143188543303 4.919625587422917E-161 transcription_factor_binding GO:0008134 12133 715 19 4 6397 8 1 false 0.007487162556502179 0.007487162556502179 0.0 cellular_response_to_oxygen_levels GO:0071453 12133 85 19 2 1663 3 2 false 0.007491727237311064 0.007491727237311064 4.192529980934564E-145 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 19 2 1663 4 2 false 0.0075739113317769766 0.0075739113317769766 5.186655572840897E-113 protein_polyubiquitination GO:0000209 12133 163 19 4 548 4 1 false 0.007625906002701355 0.007625906002701355 3.681189236491621E-144 regulation_of_protein_ubiquitination GO:0031396 12133 176 19 3 1344 4 2 false 0.0079935035302647 0.0079935035302647 8.0617715234352E-226 protein_localization_to_nuclear_pore GO:0090204 12133 1 19 1 233 2 1 false 0.00858369098712472 0.00858369098712472 0.004291845493562596 RNA_metabolic_process GO:0016070 12133 3294 19 15 5627 17 2 false 0.008966509281714503 0.008966509281714503 0.0 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 19 2 2474 6 3 false 0.009242232115186119 0.009242232115186119 1.917782059478808E-128 macromolecule_localization GO:0033036 12133 1642 19 12 3467 15 1 false 0.010311589343739828 0.010311589343739828 0.0 intracellular_transport_of_viral_material GO:0075733 12133 23 19 2 355 3 2 false 0.011600191246871767 0.011600191246871767 1.1844258992565298E-36 protein_transport GO:0015031 12133 1099 19 11 1627 11 2 false 0.01314075488906077 0.01314075488906077 0.0 cytoplasmic_transport GO:0016482 12133 666 19 11 1148 12 1 false 0.013700268964515764 0.013700268964515764 0.0 nuclear_pore GO:0005643 12133 69 19 2 2781 8 3 false 0.015425447775654367 0.015425447775654367 8.971129873692015E-140 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 19 10 174 10 1 false 0.016559057201016233 0.016559057201016233 2.5039480990851377E-47 intracellular_organelle_part GO:0044446 12133 5320 19 16 9083 19 3 false 0.01698337731497372 0.01698337731497372 0.0 regulation_of_innate_immune_response GO:0045088 12133 226 19 3 868 3 3 false 0.01747761872342346 0.01747761872342346 2.196344369914344E-215 Notch_signaling_pathway GO:0007219 12133 113 19 2 1975 4 1 false 0.01804701352420469 0.01804701352420469 2.33429872590278E-187 regulation_of_cell_cycle GO:0051726 12133 659 19 4 6583 11 2 false 0.01850588963294477 0.01850588963294477 0.0 GTP_binding GO:0005525 12133 292 19 3 1635 4 3 false 0.019592544636628892 0.019592544636628892 0.0 negative_regulation_of_protein_modification_process GO:0031400 12133 328 19 3 2431 5 3 false 0.019736621620159885 0.019736621620159885 0.0 prostate_gland_growth GO:0060736 12133 10 19 1 498 1 3 false 0.020080321285142907 0.020080321285142907 4.236088489692508E-21 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 19 5 201 10 3 false 0.020347060665896793 0.020347060665896793 2.854176062301069E-41 cellular_response_to_hypoxia GO:0071456 12133 79 19 2 1210 4 3 false 0.023176030193653403 0.023176030193653403 3.484581288071841E-126 cellular_metabolic_process GO:0044237 12133 7256 19 17 10007 18 2 false 0.023927681559787813 0.023927681559787813 0.0 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 19 2 2180 5 2 false 0.02443489034237547 0.02443489034237547 1.341003616993524E-193 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 19 2 1130 2 2 false 0.02525533599318895 0.02525533599318895 1.9819409219356823E-214 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 19 2 1813 4 1 false 0.02660543367134932 0.02660543367134932 4.219154160176784E-199 organelle GO:0043226 12133 7980 19 18 10701 19 1 false 0.02826772200960673 0.02826772200960673 0.0 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 19 10 145 10 1 false 0.028619304804221788 0.028619304804221788 1.7288474062512548E-37 macromolecule_metabolic_process GO:0043170 12133 6052 19 17 7451 17 1 false 0.029026762361485763 0.029026762361485763 0.0 regulation_of_defense_response GO:0031347 12133 387 19 3 1253 3 2 false 0.02930530796239383 0.02930530796239383 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 19 3 341 4 4 false 0.029634504701118582 0.029634504701118582 3.257446469032824E-75 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 19 14 5597 17 2 false 0.032281102270339555 0.032281102270339555 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 19 14 5588 17 2 false 0.03315629902653903 0.03315629902653903 0.0 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 19 3 2943 9 3 false 0.033182421626708064 0.033182421626708064 0.0 response_to_hypoxia GO:0001666 12133 200 19 2 2540 4 2 false 0.033289129320657126 0.033289129320657126 2.6634431659671552E-303 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 19 14 5686 17 2 false 0.033696809589598684 0.033696809589598684 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 19 14 5629 17 2 false 0.03503724855594395 0.03503724855594395 0.0 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 19 3 362 4 4 false 0.035171104431108824 0.035171104431108824 1.827388630734988E-82 regulation_of_binding GO:0051098 12133 172 19 2 9142 16 2 false 0.03552669721104814 0.03552669721104814 0.0 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 19 2 197 2 3 false 0.03838185020200678 0.03838185020200678 3.777320475653026E-42 telomeric_DNA_binding GO:0042162 12133 16 19 1 1189 3 1 false 0.039862339873044016 0.039862339873044016 1.4512187070438412E-36 establishment_of_localization_in_cell GO:0051649 12133 1633 19 12 2978 15 2 false 0.04091496241014812 0.04091496241014812 0.0 negative_regulation_of_molecular_function GO:0044092 12133 735 19 4 10257 19 2 false 0.042726988744464664 0.042726988744464664 0.0 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 19 2 859 2 3 false 0.0432307312400881 0.0432307312400881 3.480270935062193E-190 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 19 5 742 5 2 false 0.043332817452828416 0.043332817452828416 9.121396596563632E-222 protein_complex_subunit_organization GO:0071822 12133 989 19 13 1256 13 1 false 0.04398959424726216 0.04398959424726216 2.2763776011987297E-281 cellular_protein_catabolic_process GO:0044257 12133 409 19 5 3174 16 3 false 0.045147145175875224 0.045147145175875224 0.0 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 19 3 389 4 3 false 0.045338232310740384 0.045338232310740384 8.074632425282073E-93 positive_regulation_of_protein_binding GO:0032092 12133 37 19 1 6397 8 3 false 0.045370058001698 0.045370058001698 2.3062856812384995E-98 proteasome_accessory_complex GO:0022624 12133 23 19 1 9248 19 3 false 0.04625456298521875 0.04625456298521875 1.6042989552874397E-69 single-organism_process GO:0044699 12133 8052 19 18 10446 19 1 false 0.04716163141143383 0.04716163141143383 0.0 negative_regulation_of_DNA_binding GO:0043392 12133 35 19 1 2119 3 3 false 0.0487603613858628 0.0487603613858628 5.275494739019896E-77 RNA_biosynthetic_process GO:0032774 12133 2751 19 14 4191 16 3 false 0.049879316981805796 0.049879316981805796 0.0 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 19 2 3297 8 3 false 0.05162121774797602 0.05162121774797602 4.623981712175632E-272 regulation_of_protein_catabolic_process GO:0042176 12133 150 19 2 1912 5 3 false 0.05222541554427276 0.05222541554427276 1.3832082048306078E-227 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 19 2 953 5 3 false 0.05360143631203902 0.05360143631203902 1.5807807987211998E-114 cell_cycle_process GO:0022402 12133 953 19 5 7541 17 2 false 0.05376385552497344 0.05376385552497344 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 19 2 1384 3 2 false 0.053772208379296624 0.053772208379296624 1.3395090025049634E-243 cell_cycle GO:0007049 12133 1295 19 6 7541 17 1 false 0.0569647509919116 0.0569647509919116 0.0 negative_regulation_of_catalytic_activity GO:0043086 12133 588 19 3 4970 8 3 false 0.05850359145310777 0.05850359145310777 0.0 negative_regulation_of_metabolic_process GO:0009892 12133 1354 19 6 8327 18 3 false 0.058741274823292194 0.058741274823292194 0.0 cellular_response_to_stress GO:0033554 12133 1124 19 4 4743 7 2 false 0.05902572453854088 0.05902572453854088 0.0 protein_catabolic_process GO:0030163 12133 498 19 5 3569 16 2 false 0.06065359431342651 0.06065359431342651 0.0 negative_regulation_of_cell_cycle GO:0045786 12133 298 19 3 3131 10 3 false 0.06183697902568592 0.06183697902568592 0.0 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 19 6 7606 18 4 false 0.0626040057372059 0.0626040057372059 0.0 cellular_protein_complex_localization GO:0034629 12133 5 19 1 930 12 2 false 0.06300468211634117 0.06300468211634117 1.7435880605018067E-13 guanyl_nucleotide_binding GO:0019001 12133 450 19 3 1650 4 1 false 0.06431207566089374 0.06431207566089374 0.0 guanyl_ribonucleotide_binding GO:0032561 12133 450 19 3 1641 4 2 false 0.06528488776787891 0.06528488776787891 0.0 nucleus GO:0005634 12133 4764 19 10 7259 11 1 false 0.06562998349640342 0.06562998349640342 0.0 antigen_processing_and_presentation GO:0019882 12133 185 19 2 1618 4 1 false 0.06677544873295935 0.06677544873295935 5.091289488805967E-249 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 19 1 243 1 2 false 0.06995884773662231 0.06995884773662231 1.7559807727942103E-26 regulation_of_immune_response GO:0050776 12133 533 19 3 2461 5 3 false 0.07124597074162688 0.07124597074162688 0.0 virion_assembly GO:0019068 12133 11 19 1 2070 14 4 false 0.07209915246591625 0.07209915246591625 1.3710102562261885E-29 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 19 2 278 2 3 false 0.07402020621770027 0.07402020621770027 2.8121052478162137E-70 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 19 3 2556 3 1 false 0.0763686001761799 0.0763686001761799 0.0 palate_development GO:0060021 12133 62 19 1 3099 4 1 false 0.07769261948937362 0.07769261948937362 2.0367343521071395E-131 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 19 5 200 10 3 false 0.07877439930119473 0.07877439930119473 7.491323649368413E-49 organic_substance_transport GO:0071702 12133 1580 19 11 2783 14 1 false 0.08081909992560689 0.08081909992560689 0.0 Notch_receptor_processing GO:0007220 12133 17 19 1 3038 16 1 false 0.08607527156454385 0.08607527156454385 2.325698863690895E-45 female_sex_differentiation GO:0046660 12133 93 19 1 3074 3 2 false 0.0880708283660161 0.0880708283660161 2.0765356282751238E-180 prostate_gland_development GO:0030850 12133 45 19 1 508 1 3 false 0.0885826771653691 0.0885826771653691 1.535189924421617E-65 regulation_of_cell_cycle_arrest GO:0071156 12133 89 19 2 481 3 2 false 0.08944461564503181 0.08944461564503181 1.91357850692127E-99 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 19 14 4989 17 5 false 0.09007793435809246 0.09007793435809246 0.0 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 19 2 198 2 2 false 0.09075526842023063 0.09075526842023063 2.9049351003528108E-52 regulation_of_response_to_stress GO:0080134 12133 674 19 3 3466 6 2 false 0.09201537695918578 0.09201537695918578 0.0 coated_pit GO:0005905 12133 52 19 1 10213 19 3 false 0.0925096582412156 0.0925096582412156 3.070128605674566E-141 mitotic_cell_cycle GO:0000278 12133 625 19 5 1295 6 1 false 0.093405313679331 0.093405313679331 0.0 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 19 1 1977 5 3 false 0.09491109239340043 0.09491109239340043 8.49513097758148E-83 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 19 2 86 2 2 false 0.09603283173734763 0.09603283173734763 6.233113581740502E-23 nuclear_body_organization GO:0030575 12133 6 19 1 62 1 1 false 0.09677419354838807 0.09677419354838807 1.626690238926508E-8 microtubule_cytoskeleton_organization GO:0000226 12133 259 19 2 831 2 2 false 0.09688138836934784 0.09688138836934784 4.0880234187670296E-223 positive_regulation_of_defense_response GO:0031349 12133 229 19 2 1621 4 3 false 0.09816164913832477 0.09816164913832477 6.85443065618377E-286 response_to_oxygen_levels GO:0070482 12133 214 19 2 676 2 1 false 0.09989480604870983 0.09989480604870983 1.6255941364061853E-182 regulation_of_cellular_amino_acid_metabolic_process GO:0006521 12133 55 19 1 4147 8 4 false 0.10138584179914771 0.10138584179914771 1.925356420452305E-126 regulation_of_immune_system_process GO:0002682 12133 794 19 3 6789 10 2 false 0.10217071883870331 0.10217071883870331 0.0 positive_regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014068 12133 45 19 1 798 2 3 false 0.10966877670963003 0.10966877670963003 1.088358768929943E-74 basal_transcription_machinery_binding GO:0001098 12133 464 19 2 6397 8 1 false 0.10985558845327052 0.10985558845327052 0.0 nuclear_envelope GO:0005635 12133 258 19 2 3962 9 3 false 0.1123259815443998 0.1123259815443998 0.0 regulation_of_protein_binding GO:0043393 12133 95 19 1 6398 8 2 false 0.11285235961751816 0.11285235961751816 5.5524328548337306E-214 immune_response-regulating_signaling_pathway GO:0002764 12133 310 19 2 3626 7 2 false 0.11483509458913754 0.11483509458913754 0.0 ERBB_signaling_pathway GO:0038127 12133 199 19 2 586 2 1 false 0.1149383040168364 0.1149383040168364 2.435227003721618E-162 cell_cycle_phase_transition GO:0044770 12133 415 19 4 953 5 1 false 0.11654597731950708 0.11654597731950708 1.4433288987581492E-282 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 19 6 6103 17 3 false 0.11655563659182687 0.11655563659182687 0.0 nucleus_organization GO:0006997 12133 62 19 1 2031 4 1 false 0.11671119803082616 0.11671119803082616 6.73570952581451E-120 regulation_of_DNA_binding GO:0051101 12133 67 19 1 2162 4 2 false 0.11839354128497535 0.11839354128497535 3.7616659824415835E-129 fertilization GO:0009566 12133 65 19 1 546 1 2 false 0.11904761904764036 0.11904761904764036 5.279047514007133E-86 cytokine-mediated_signaling_pathway GO:0019221 12133 318 19 2 2013 4 2 false 0.11988709984588 0.11988709984588 0.0 negative_regulation_of_binding GO:0051100 12133 72 19 1 9054 16 3 false 0.12001600083215704 0.12001600083215704 1.0408990583833388E-181 innate_immune_response GO:0045087 12133 626 19 3 1268 3 2 false 0.12003540610840648 0.12003540610840648 0.0 ovulation_cycle GO:0042698 12133 77 19 1 640 1 3 false 0.12031250000000027 0.12031250000000027 1.431548427183746E-101 positive_regulation_of_binding GO:0051099 12133 73 19 1 9050 16 3 false 0.12163412758737337 0.12163412758737337 8.738239425278628E-184 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 19 5 5447 17 3 false 0.12226054166905839 0.12226054166905839 0.0 DNA_damage_checkpoint GO:0000077 12133 126 19 2 574 3 2 false 0.12289778922392475 0.12289778922392475 1.5833464450994651E-130 regulation_of_response_to_stimulus GO:0048583 12133 2074 19 5 7292 10 2 false 0.12469695634105825 0.12469695634105825 0.0 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 19 3 506 4 3 false 0.12539200155645489 0.12539200155645489 1.5079927652081954E-141 cytoplasmic_microtubule GO:0005881 12133 41 19 1 5210 17 2 false 0.12586272799554563 0.12586272799554563 1.5944596258703277E-103 regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014066 12133 54 19 1 1607 4 2 false 0.12790087602775943 0.12790087602775943 4.2614304493416375E-102 SUMO_ligase_activity GO:0019789 12133 9 19 1 335 5 1 false 0.12802751617703595 0.12802751617703595 7.610794818623194E-18 regulation_of_cellular_amine_metabolic_process GO:0033238 12133 69 19 1 4026 8 3 false 0.1292659997161102 0.1292659997161102 5.643300821418702E-151 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 19 3 415 4 3 false 0.13179441334607428 0.13179441334607428 9.462933237946419E-117 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 19 2 3842 6 3 false 0.13240197650184804 0.13240197650184804 0.0 hormone_receptor_binding GO:0051427 12133 122 19 1 918 1 1 false 0.1328976034858756 0.1328976034858756 1.5301276126382055E-155 membrane-enclosed_lumen GO:0031974 12133 3005 19 8 10701 19 1 false 0.1353781563682315 0.1353781563682315 0.0 single-organism_cellular_process GO:0044763 12133 7541 19 17 9888 19 2 false 0.13612964270225975 0.13612964270225975 0.0 nuclear_lumen GO:0031981 12133 2490 19 8 3186 8 2 false 0.13885446046483793 0.13885446046483793 0.0 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 19 2 170 2 3 false 0.14034110685692527 0.14034110685692527 2.004129732487635E-48 organelle_fission GO:0048285 12133 351 19 2 2031 4 1 false 0.1404172853858459 0.1404172853858459 0.0 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 19 3 220 4 1 false 0.14239945656794112 0.14239945656794112 2.4407604211478482E-62 GTP_metabolic_process GO:0046039 12133 625 19 3 1193 3 3 false 0.14345780882292297 0.14345780882292297 0.0 proteasomal_protein_catabolic_process GO:0010498 12133 231 19 4 498 5 2 false 0.14434163452827595 0.14434163452827595 1.2543475178088858E-148 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 19 2 207 2 2 false 0.1445054171943169 0.1445054171943169 2.976076769798144E-59 positive_regulation_of_innate_immune_response GO:0045089 12133 178 19 2 740 3 4 false 0.1453584975450633 0.1453584975450633 1.4450011889246649E-176 small_conjugating_protein_ligase_binding GO:0044389 12133 147 19 1 1005 1 1 false 0.1462686567164614 0.1462686567164614 6.302468729220369E-181 ovulation_cycle_process GO:0022602 12133 71 19 1 8057 18 3 false 0.14742315894595273 0.14742315894595273 5.317350826514013E-176 regulation_of_cytokine-mediated_signaling_pathway GO:0001959 12133 70 19 1 1785 4 3 false 0.14799145210624923 0.14799145210624923 1.145730192869727E-127 gonad_development GO:0008406 12133 150 19 1 2876 3 4 false 0.14849742268369953 0.14849742268369953 4.529833702866928E-255 metabolic_process GO:0008152 12133 8027 19 17 10446 19 1 false 0.14900503246064456 0.14900503246064456 0.0 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 19 5 5032 17 4 false 0.14976573191168613 0.14976573191168613 0.0 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 19 1 1672 4 5 false 0.15103476958542517 0.15103476958542517 1.5388096674355026E-121 positive_regulation_of_protein_modification_process GO:0031401 12133 708 19 3 2417 5 3 false 0.15362614842622546 0.15362614842622546 0.0 regulation_of_response_to_cytokine_stimulus GO:0060759 12133 76 19 1 2275 5 2 false 0.1563679384364703 0.1563679384364703 4.9547358949088833E-144 development_of_primary_sexual_characteristics GO:0045137 12133 174 19 1 3105 3 3 false 0.15891920256160552 0.15891920256160552 2.1612319791507408E-290 positive_regulation_of_metabolic_process GO:0009893 12133 1872 19 6 8366 17 3 false 0.16034013411400683 0.16034013411400683 0.0 negative_regulation_of_cellular_process GO:0048523 12133 2515 19 7 9689 18 3 false 0.1617400649060005 0.1617400649060005 0.0 response_to_cytokine_stimulus GO:0034097 12133 461 19 2 1783 3 1 false 0.16582464253271392 0.16582464253271392 0.0 intracellular_part GO:0044424 12133 9083 19 19 9983 19 2 false 0.16582826268833445 0.16582826268833445 0.0 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 19 1 1054 2 3 false 0.17049146650674626 0.17049146650674626 5.573854633657796E-137 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 19 1 953 5 4 false 0.17096169605528005 0.17096169605528005 1.0482452124052062E-64 nucleoplasm GO:0005654 12133 1443 19 6 2767 8 2 false 0.17422738002650273 0.17422738002650273 0.0 immune_response GO:0006955 12133 1006 19 3 5335 8 2 false 0.17833409904091613 0.17833409904091613 0.0 defense_response GO:0006952 12133 1018 19 3 2540 4 1 false 0.17992675648875778 0.17992675648875778 0.0 protein_C-terminus_binding GO:0008022 12133 157 19 1 6397 8 1 false 0.1803696226510076 0.1803696226510076 2.34014E-319 ribose_phosphate_metabolic_process GO:0019693 12133 1207 19 3 3007 4 3 false 0.18065952312646538 0.18065952312646538 0.0 molecular_function GO:0003674 12133 10257 19 19 11221 19 1 false 0.18120256097847834 0.18120256097847834 0.0 viral_reproductive_process GO:0022415 12133 557 19 12 783 14 2 false 0.18165624226077542 0.18165624226077542 1.4346997744229993E-203 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 19 2 1398 3 2 false 0.1821435079548099 0.1821435079548099 0.0 activation_of_innate_immune_response GO:0002218 12133 155 19 2 362 2 2 false 0.18265713717270493 0.18265713717270493 1.0665156090103768E-106 BMP_signaling_pathway GO:0030509 12133 83 19 1 1276 3 2 false 0.18285679547917866 0.18285679547917866 9.874891335860256E-133 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 19 1 2735 7 4 false 0.18352758571449057 0.18352758571449057 2.836340851870023E-153 sequence-specific_DNA_binding GO:0043565 12133 1189 19 3 2091 3 1 false 0.18365817113669242 0.18365817113669242 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 19 3 5778 8 3 false 0.18621741720456242 0.18621741720456242 0.0 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 19 3 1975 4 1 false 0.18663293600425357 0.18663293600425357 0.0 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 19 6 7638 17 4 false 0.18722497482249034 0.18722497482249034 0.0 negative_regulation_of_nuclear_division GO:0051784 12133 43 19 1 436 2 3 false 0.18772540335334276 0.18772540335334276 1.634686522119006E-60 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 19 5 3631 15 4 false 0.18865609274984702 0.18865609274984702 0.0 GTPase_activity GO:0003924 12133 612 19 3 1061 3 2 false 0.19151608627176514 0.19151608627176514 4.702100395E-313 endomembrane_system GO:0012505 12133 1211 19 4 9983 19 1 false 0.1916779171200736 0.1916779171200736 0.0 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 19 1 6380 10 3 false 0.19266950887718637 0.19266950887718637 2.5067679665083333E-283 regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060334 12133 22 19 1 114 1 3 false 0.1929824561403555 0.1929824561403555 5.496543393824805E-24 primary_metabolic_process GO:0044238 12133 7288 19 17 8027 17 1 false 0.19328116084836702 0.19328116084836702 0.0 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 19 3 2877 5 6 false 0.19549528215049625 0.19549528215049625 0.0 protein_localization GO:0008104 12133 1434 19 12 1642 12 1 false 0.1956893535178934 0.1956893535178934 3.426309620265761E-270 type_I_interferon_production GO:0032606 12133 71 19 1 362 1 1 false 0.19613259668509953 0.19613259668509953 2.8677775679244762E-77 activation_of_immune_response GO:0002253 12133 341 19 2 1618 4 2 false 0.19735384915459886 0.19735384915459886 0.0 intracellular GO:0005622 12133 9171 19 19 9983 19 1 false 0.199203661717375 0.199203661717375 0.0 regulation_of_response_to_interferon-gamma GO:0060330 12133 23 19 1 319 3 3 false 0.2016671645347126 0.2016671645347126 1.507111625705858E-35 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 19 2 803 3 1 false 0.20186003105731287 0.20186003105731287 7.141936114023743E-209 anion_binding GO:0043168 12133 2280 19 4 4448 5 1 false 0.20349331588132794 0.20349331588132794 0.0 positive_regulation_of_cell_cycle GO:0045787 12133 98 19 1 3492 8 3 false 0.2038404163348195 0.2038404163348195 2.23767062140918E-193 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 19 1 201 1 3 false 0.20398009950248341 0.20398009950248341 9.949481941404742E-44 regulation_of_type_I_interferon_production GO:0032479 12133 67 19 1 325 1 2 false 0.2061538461538324 0.2061538461538324 2.788484219003069E-71 regulation_of_cytokine_production GO:0001817 12133 323 19 1 1562 1 2 false 0.20678617157496743 0.20678617157496743 0.0 negative_regulation_of_biological_process GO:0048519 12133 2732 19 7 10446 19 2 false 0.20756924327621912 0.20756924327621912 0.0 microtubule-based_process GO:0007017 12133 378 19 2 7541 17 1 false 0.20848290526277083 0.20848290526277083 0.0 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 19 3 5051 8 3 false 0.20856043429178772 0.20856043429178772 0.0 developmental_growth GO:0048589 12133 223 19 1 2952 3 2 false 0.2100029656228817 0.2100029656228817 0.0 endocytosis GO:0006897 12133 411 19 2 895 2 2 false 0.2106032769674332 0.2106032769674332 2.7872223899360555E-267 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 19 2 158 2 2 false 0.21188422155928965 0.21188422155928965 6.794891168245598E-47 positive_regulation_of_molecular_function GO:0044093 12133 1303 19 4 10257 19 2 false 0.21496530931262342 0.21496530931262342 0.0 negative_regulation_of_cytokine_production GO:0001818 12133 114 19 1 529 1 3 false 0.21550094517957671 0.21550094517957671 4.407958658606205E-119 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 19 1 148 1 3 false 0.21621621621620796 0.21621621621620796 3.492638478654734E-33 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 19 3 1053 3 1 false 0.21785283660815685 0.21785283660815685 1.6418245301060377E-306 protein_complex_localization GO:0031503 12133 29 19 1 1434 12 1 false 0.21817192829055448 0.21817192829055448 3.39152835029198E-61 protein_export_from_nucleus GO:0006611 12133 46 19 1 2428 13 3 false 0.22063732270531156 0.22063732270531156 1.6048237175829586E-98 protein_K48-linked_ubiquitination GO:0070936 12133 37 19 2 163 4 1 false 0.22192214220087453 0.22192214220087453 1.6289154422281443E-37 reproductive_system_development GO:0061458 12133 216 19 1 2686 3 1 false 0.22244630648149705 0.22244630648149705 0.0 response_to_growth_factor_stimulus GO:0070848 12133 545 19 2 1783 3 1 false 0.22303657626692783 0.22303657626692783 0.0 signal_transduction GO:0007165 12133 3547 19 7 6702 10 4 false 0.22386693155269516 0.22386693155269516 0.0 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 19 1 1679 4 3 false 0.22389498027376542 0.22389498027376542 1.5952227787322578E-167 protein_binding_transcription_factor_activity GO:0000988 12133 488 19 2 10311 19 3 false 0.22620126261409138 0.22620126261409138 0.0 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 19 3 217 3 2 false 0.22821538718009737 0.22821538718009737 2.2668758893633536E-62 pigment_granule GO:0048770 12133 87 19 1 712 2 1 false 0.2296022377093135 0.2296022377093135 3.4546414966613156E-114 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 19 1 835 1 2 false 0.23233532934123596 0.23233532934123596 8.0742416973675315E-196 positive_regulation_of_proteolysis GO:0045862 12133 69 19 1 1334 5 3 false 0.23352941725407966 0.23352941725407966 2.369917275782091E-117 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 19 3 541 4 2 false 0.2346513220949496 0.2346513220949496 1.01164377942614E-160 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 19 4 673 5 2 false 0.2353973193320656 0.2353973193320656 4.9348138289436974E-201 urogenital_system_development GO:0001655 12133 231 19 1 2686 3 1 false 0.23653208009694324 0.23653208009694324 0.0 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 19 1 522 1 3 false 0.23754789272030183 0.23754789272030183 1.2617392241842968E-123 regulation_of_cellular_ketone_metabolic_process GO:0010565 12133 133 19 1 3992 8 2 false 0.23762464542420628 0.23762464542420628 1.512735013638228E-252 rhythmic_process GO:0048511 12133 148 19 1 10446 19 1 false 0.23765394293284872 0.23765394293284872 0.0 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 19 2 305 2 2 false 0.2378343399482245 0.2378343399482245 3.640759676212702E-91 negative_regulation_of_mitosis GO:0045839 12133 43 19 1 656 4 5 false 0.2380142090566087 0.2380142090566087 1.8426541499010044E-68 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 19 5 504 5 1 false 0.23888094246269134 0.23888094246269134 6.011520399617331E-122 gland_development GO:0048732 12133 251 19 1 2873 3 2 false 0.2399402306147205 0.2399402306147205 0.0 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 19 2 130 2 2 false 0.2404293381037601 0.2404293381037601 1.0680656075518395E-38 proteolysis GO:0006508 12133 732 19 5 3431 16 1 false 0.2430203386430084 0.2430203386430084 0.0 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 19 2 260 3 3 false 0.2447904075811306 0.2447904075811306 1.712440969539876E-70 mRNA_binding GO:0003729 12133 91 19 2 763 8 1 false 0.24540496942882442 0.24540496942882442 1.7788235024198917E-120 positive_regulation_of_cellular_process GO:0048522 12133 2811 19 7 9694 18 3 false 0.24666580799238996 0.24666580799238996 0.0 protein_sumoylation GO:0016925 12133 32 19 1 578 5 1 false 0.24858252862991687 0.24858252862991687 2.618927943730716E-53 reproductive_structure_development GO:0048608 12133 216 19 1 3110 4 3 false 0.2502957613165412 0.2502957613165412 0.0 positive_regulation_of_immune_response GO:0050778 12133 394 19 2 1600 4 4 false 0.2552693106637079 0.2552693106637079 0.0 mitotic_spindle_organization GO:0007052 12133 37 19 1 648 5 2 false 0.25539967454864687 0.25539967454864687 3.6765869552528886E-61 biological_process GO:0008150 12133 10446 19 19 11221 19 1 false 0.2564242780991747 0.2564242780991747 0.0 cellular_membrane_organization GO:0016044 12133 784 19 3 7541 17 2 false 0.25675431880113714 0.25675431880113714 0.0 cell_division GO:0051301 12133 438 19 2 7541 17 1 false 0.25932447803733355 0.25932447803733355 0.0 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 19 3 929 6 2 false 0.2597975574918555 0.2597975574918555 1.7613668775256747E-246 embryonic_organ_development GO:0048568 12133 275 19 1 2873 3 3 false 0.26062879912190723 0.26062879912190723 0.0 regulation_of_nuclear_division GO:0051783 12133 100 19 1 712 2 2 false 0.26134262551571663 0.26134262551571663 7.811073934054147E-125 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 19 1 650 1 2 false 0.26307692307691666 0.26307692307691666 6.010278185218431E-162 small_molecule_binding GO:0036094 12133 2102 19 5 8962 15 1 false 0.26354647243973695 0.26354647243973695 0.0 GTP_catabolic_process GO:0006184 12133 614 19 3 957 3 4 false 0.26363742804817175 0.26363742804817175 2.3934835856107606E-270 regulation_of_signaling GO:0023051 12133 1793 19 4 6715 10 2 false 0.2650275226895853 0.2650275226895853 0.0 cell_part GO:0044464 12133 9983 19 19 10701 19 2 false 0.26693019313787225 0.26693019313787225 0.0 cell GO:0005623 12133 9984 19 19 10701 19 1 false 0.26743914182357975 0.26743914182357975 0.0 cell_cycle_arrest GO:0007050 12133 202 19 2 998 5 2 false 0.2674552341164177 0.2674552341164177 1.5077994882682823E-217 rRNA_binding GO:0019843 12133 29 19 1 763 8 1 false 0.2676169977028419 0.2676169977028419 3.8668021308986908E-53 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 19 3 956 3 2 false 0.2683683854557507 0.2683683854557507 3.936677708897206E-269 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 19 3 2807 4 3 false 0.26860861972518557 0.26860861972518557 0.0 nucleic_acid_binding GO:0003676 12133 2849 19 10 4407 13 2 false 0.2690453247906801 0.2690453247906801 0.0 nuclear_membrane GO:0031965 12133 157 19 1 4084 8 3 false 0.2693958188161229 0.2693958188161229 2.8056123615014062E-288 amine_metabolic_process GO:0009308 12133 139 19 1 1841 4 1 false 0.26968987487167834 0.26968987487167834 2.897401461446105E-213 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 19 3 2771 7 5 false 0.27491849580637473 0.27491849580637473 0.0 endocytic_vesicle_membrane GO:0030666 12133 97 19 1 352 1 2 false 0.27556818181817483 0.27556818181817483 2.1109282121886535E-89 'de_novo'_protein_folding GO:0006458 12133 51 19 1 183 1 1 false 0.27868852459015203 0.27868852459015203 1.4322240237766098E-46 response_to_abiotic_stimulus GO:0009628 12133 676 19 2 5200 8 1 false 0.27941593820975064 0.27941593820975064 0.0 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 19 1 1198 5 4 false 0.27983169805835933 0.27983169805835933 2.335035261625238E-122 negative_regulation_of_organelle_organization GO:0010639 12133 168 19 1 2125 4 3 false 0.2808455424445956 0.2808455424445956 2.2467097914760192E-254 organic_substance_metabolic_process GO:0071704 12133 7451 19 17 8027 17 1 false 0.2816258219606641 0.2816258219606641 0.0 endosome_membrane GO:0010008 12133 248 19 1 1627 2 2 false 0.2817007887352579 0.2817007887352579 8.244139595488818E-301 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 19 1 1130 2 2 false 0.28287073688855463 0.28287073688855463 2.620015602340521E-209 PML_body GO:0016605 12133 77 19 1 272 1 1 false 0.28308823529409977 0.28308823529409977 7.662735942565743E-70 positive_regulation_of_immune_system_process GO:0002684 12133 540 19 2 3595 7 3 false 0.2839606067921069 0.2839606067921069 0.0 positive_regulation_of_cytokine_production GO:0001819 12133 175 19 1 614 1 3 false 0.2850162866449984 0.2850162866449984 1.2195240299259301E-158 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 19 1 856 1 3 false 0.285046728972063 0.285046728972063 2.175375701359491E-221 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 19 3 3605 16 4 false 0.286254795394004 0.286254795394004 0.0 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 19 2 163 2 1 false 0.2899341058849978 0.2899341058849978 2.2957799692832176E-48 response_to_interferon-gamma GO:0034341 12133 97 19 1 900 3 2 false 0.29002363427798555 0.29002363427798555 5.665951698458868E-133 angiogenesis GO:0001525 12133 300 19 1 2776 3 3 false 0.29052575760380017 0.29052575760380017 0.0 regulation_of_cell_communication GO:0010646 12133 1796 19 4 6469 10 2 false 0.29177512107072917 0.29177512107072917 0.0 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 19 2 7293 11 3 false 0.292528031192741 0.292528031192741 0.0 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 19 2 116 2 3 false 0.2928035982009022 0.2928035982009022 2.4978330889301296E-34 intracellular_organelle GO:0043229 12133 7958 19 18 9096 19 2 false 0.29299503432816315 0.29299503432816315 0.0 cellular_ketone_metabolic_process GO:0042180 12133 155 19 1 7667 17 3 false 0.29359659108206326 0.29359659108206326 0.0 ubiquitin-protein_ligase_activity GO:0004842 12133 321 19 4 558 5 2 false 0.29456138480564464 0.29456138480564464 1.7708856343357755E-164 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 19 4 381 5 2 false 0.29759650937765725 0.29759650937765725 4.820433761728018E-112 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 19 1 557 12 2 false 0.29763751250115195 0.29763751250115195 3.0295698614548545E-31 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 19 4 2560 5 2 false 0.29808980725965106 0.29808980725965106 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 19 3 442 4 3 false 0.2981666598174631 0.2981666598174631 2.4953498472018727E-132 regulation_of_protein_modification_process GO:0031399 12133 1001 19 3 2566 5 2 false 0.30033474995216264 0.30033474995216264 0.0 cytoskeleton-dependent_intracellular_transport GO:0030705 12133 67 19 1 2454 13 2 false 0.3028545636531934 0.3028545636531934 6.842684271212845E-133 negative_regulation_of_signaling GO:0023057 12133 597 19 2 4884 9 3 false 0.30300584655309015 0.30300584655309015 0.0 transcription_coactivator_activity GO:0003713 12133 264 19 2 478 2 2 false 0.30451830215001674 0.30451830215001674 4.798051856605128E-142 negative_regulation_of_cell_communication GO:0010648 12133 599 19 2 4860 9 3 false 0.3065959059017451 0.3065959059017451 0.0 G1_DNA_damage_checkpoint GO:0044783 12133 70 19 2 126 2 1 false 0.30666666666666786 0.30666666666666786 3.590272155218709E-37 regulation_of_protein_complex_assembly GO:0043254 12133 185 19 1 1610 3 3 false 0.3067948361984307 0.3067948361984307 1.34790682725651E-248 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 19 1 695 3 3 false 0.30748935789060194 0.30748935789060194 3.5521820546065696E-107 negative_regulation_of_signal_transduction GO:0009968 12133 571 19 2 3588 7 5 false 0.3090259185209423 0.3090259185209423 0.0 cytokine_production GO:0001816 12133 362 19 1 4095 4 1 false 0.3095144542223321 0.3095144542223321 0.0 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 19 3 3910 16 3 false 0.3101257385124291 0.3101257385124291 0.0 cellular_response_to_organic_substance GO:0071310 12133 1347 19 3 1979 3 2 false 0.3151056491357644 0.3151056491357644 0.0 positive_regulation_of_biological_process GO:0048518 12133 3081 19 7 10446 19 2 false 0.3165293988541315 0.3165293988541315 0.0 receptor_signaling_protein_activity GO:0005057 12133 339 19 1 1070 1 1 false 0.3168224299066703 0.3168224299066703 2.5248591221043436E-289 protein_maturation GO:0051604 12133 123 19 1 5551 17 2 false 0.317150803495099 0.317150803495099 1.3126924681575497E-255 regulation_of_molecular_function GO:0065009 12133 2079 19 5 10494 19 2 false 0.31892694822025935 0.31892694822025935 0.0 DNA-dependent_transcription,_initiation GO:0006352 12133 225 19 2 2751 14 2 false 0.3195932155962858 0.3195932155962858 0.0 response_to_DNA_damage_stimulus GO:0006974 12133 570 19 3 1124 4 1 false 0.32292682831574127 0.32292682831574127 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 19 1 2025 4 2 false 0.32297506625757255 0.32297506625757255 5.184659787643375E-271 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 19 2 269 3 2 false 0.3269383627785909 0.3269383627785909 3.613555574654199E-77 regulation_of_signal_transduction GO:0009966 12133 1603 19 4 3826 7 4 false 0.3272117368711861 0.3272117368711861 0.0 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 19 1 591 5 3 false 0.3279262295619928 0.3279262295619928 1.267222544612779E-68 inositol_lipid-mediated_signaling GO:0048017 12133 173 19 1 1813 4 1 false 0.33068222936699226 0.33068222936699226 3.525454591975737E-247 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 19 2 5830 10 3 false 0.33334442620935034 0.33334442620935034 0.0 viral_protein_processing GO:0019082 12133 10 19 1 256 10 2 false 0.333550095553339 0.333550095553339 3.5864633505920636E-18 nuclear_body GO:0016604 12133 272 19 1 805 1 1 false 0.3378881987577754 0.3378881987577754 8.12188174084084E-223 immune_system_process GO:0002376 12133 1618 19 4 10446 19 1 false 0.33827909642290777 0.33827909642290777 0.0 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 19 2 1356 3 2 false 0.3408781719616921 0.3408781719616921 0.0 regulation_of_proteolysis GO:0030162 12133 146 19 1 1822 5 2 false 0.3417055266573131 0.3417055266573131 4.197674460173735E-220 blood_vessel_morphogenesis GO:0048514 12133 368 19 1 2812 3 3 false 0.34357086843986256 0.34357086843986256 0.0 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 19 1 676 5 2 false 0.3466394995543749 0.3466394995543749 2.737610529852072E-82 nucleoside_metabolic_process GO:0009116 12133 1083 19 3 2072 4 4 false 0.34710945740457555 0.34710945740457555 0.0 envelope GO:0031975 12133 641 19 2 9983 19 1 false 0.34719608504458105 0.34719608504458105 0.0 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 19 6 6129 17 3 false 0.3473628612574556 0.3473628612574556 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 19 3 1096 6 2 false 0.3497328382049659 0.3497328382049659 7.137372224746455E-307 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 19 1 1663 5 2 false 0.35401125767979397 0.35401125767979397 7.181952736648417E-207 interferon-gamma-mediated_signaling_pathway GO:0060333 12133 66 19 1 330 2 2 false 0.36048632218842164 0.36048632218842164 3.5052495329479947E-71 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 19 1 859 2 3 false 0.3605591149250145 0.3605591149250145 4.662302019201105E-186 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 19 2 129 2 1 false 0.36373546511628674 0.36373546511628674 3.5310664374642874E-37 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 19 2 1541 4 3 false 0.3639703934506761 0.3639703934506761 0.0 androgen_receptor_signaling_pathway GO:0030521 12133 62 19 2 102 2 1 false 0.3671131819064124 0.3671131819064124 2.6706454874295595E-29 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 19 1 415 4 1 false 0.36926596345186424 0.36926596345186424 2.1919403735850567E-61 microtubule GO:0005874 12133 288 19 1 3267 5 3 false 0.36980028293057204 0.36980028293057204 0.0 cellular_amine_metabolic_process GO:0044106 12133 136 19 1 5073 17 2 false 0.3704226857207048 0.3704226857207048 2.7563154132003715E-271 positive_regulation_of_kinase_activity GO:0033674 12133 438 19 1 1181 1 3 false 0.37087214225224796 0.37087214225224796 0.0 brain_development GO:0007420 12133 420 19 1 2904 3 3 false 0.3742670392026678 0.3742670392026678 0.0 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 19 1 1112 1 4 false 0.37500000000008227 0.37500000000008227 1.302733E-318 positive_regulation_of_phosphorylation GO:0042327 12133 563 19 1 1487 1 3 false 0.37861466039011715 0.37861466039011715 0.0 cellular_response_to_interferon-gamma GO:0071346 12133 83 19 1 392 2 2 false 0.37906466934595223 0.37906466934595223 2.629901965674187E-87 polysome GO:0005844 12133 22 19 1 569 12 1 false 0.37992192045991324 0.37992192045991324 4.138788255326549E-40 endocytic_vesicle GO:0030139 12133 152 19 1 712 2 1 false 0.3816273961348403 0.3816273961348403 1.2528026489004738E-159 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 19 2 252 2 2 false 0.38721305255167254 0.38721305255167254 5.925442745937436E-72 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 19 2 183 3 2 false 0.3895480481840517 0.3895480481840517 1.0111677973178846E-53 ribonucleotide_catabolic_process GO:0009261 12133 946 19 3 1294 3 3 false 0.39039084482127334 0.39039084482127334 0.0 multi-multicellular_organism_process GO:0044706 12133 155 19 1 4752 15 2 false 0.3923593129027606 0.3923593129027606 7.365305875596643E-296 cell_cortex GO:0005938 12133 175 19 1 6402 18 2 false 0.3932003832414969 0.3932003832414969 0.0 nucleotide_catabolic_process GO:0009166 12133 969 19 3 1318 3 2 false 0.39707133310484327 0.39707133310484327 0.0 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 19 1 750 1 3 false 0.39866666666682765 0.39866666666682765 3.090255244762607E-218 positive_regulation_of_signaling GO:0023056 12133 817 19 2 4861 8 3 false 0.3997699622819677 0.3997699622819677 0.0 cell_cycle_phase GO:0022403 12133 253 19 2 953 5 1 false 0.39987623329620303 0.39987623329620303 1.0384727319913012E-238 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 19 2 129 2 1 false 0.40225290697674887 0.40225290697674887 2.4714073881998435E-36 cellular_component GO:0005575 12133 10701 19 19 11221 19 1 false 0.4056404546519968 0.4056404546519968 0.0 positive_regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032436 12133 35 19 1 288 4 4 false 0.4061872551922686 0.4061872551922686 7.428075320192054E-46 positive_regulation_of_cell_communication GO:0010647 12133 820 19 2 4819 8 3 false 0.40627948652397516 0.40627948652397516 0.0 chromatin_binding GO:0003682 12133 309 19 1 8962 15 1 false 0.4094664720382979 0.4094664720382979 0.0 stress-activated_MAPK_cascade GO:0051403 12133 207 19 1 504 1 2 false 0.41071428571427093 0.41071428571427093 1.7060805667457382E-147 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 19 1 912 1 2 false 0.4111842105262834 0.4111842105262834 2.059888800891414E-267 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 19 1 222 3 3 false 0.41341011929244453 0.41341011929244453 2.5456303013282065E-42 rRNA_metabolic_process GO:0016072 12133 107 19 1 258 1 1 false 0.4147286821705359 0.4147286821705359 1.860360860420455E-75 neurotrophin_signaling_pathway GO:0038179 12133 253 19 1 2018 4 2 false 0.41506330285341814 0.41506330285341814 0.0 vasculature_development GO:0001944 12133 441 19 1 2686 3 2 false 0.4162382144237807 0.4162382144237807 0.0 positive_regulation_of_proteasomal_protein_catabolic_process GO:1901800 12133 36 19 1 287 4 4 false 0.41675150321113863 0.41675150321113863 1.2079535246838254E-46 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 19 1 1631 4 2 false 0.4241306049152994 0.4241306049152994 3.3133814045702313E-271 positive_regulation_of_cellular_catabolic_process GO:0031331 12133 106 19 1 3311 17 4 false 0.42564749913349964 0.42564749913349964 4.802217577498734E-203 response_to_organic_substance GO:0010033 12133 1783 19 3 2369 3 1 false 0.426165163335362 0.426165163335362 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 19 3 2595 5 2 false 0.4276189323712644 0.4276189323712644 0.0 apoptotic_signaling_pathway GO:0097190 12133 305 19 1 3954 7 2 false 0.4301410486414844 0.4301410486414844 0.0 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 19 1 5033 9 3 false 0.4316357923849749 0.4316357923849749 0.0 nuclear_part GO:0044428 12133 2767 19 8 6936 18 2 false 0.4328062314901909 0.4328062314901909 0.0 signal_transduction_by_phosphorylation GO:0023014 12133 307 19 1 3947 7 2 false 0.432919524656724 0.432919524656724 0.0 phosphatidylinositol_3-kinase_cascade GO:0014065 12133 75 19 1 173 1 1 false 0.4335260115606976 0.4335260115606976 6.333263082873936E-51 DNA_metabolic_process GO:0006259 12133 791 19 3 5627 17 2 false 0.43528807655573937 0.43528807655573937 0.0 organelle_envelope GO:0031967 12133 629 19 2 7756 18 3 false 0.4353402677186733 0.4353402677186733 0.0 blood_vessel_development GO:0001568 12133 420 19 1 3152 4 3 false 0.43577704459785493 0.43577704459785493 0.0 RNA_export_from_nucleus GO:0006405 12133 72 19 1 165 1 2 false 0.43636363636365744 0.43636363636365744 1.3059643179360761E-48 rRNA_processing GO:0006364 12133 102 19 1 231 1 3 false 0.4415584415584419 0.4415584415584419 2.6685808966337758E-68 cytoskeleton_organization GO:0007010 12133 719 19 2 2031 4 1 false 0.444163162630808 0.444163162630808 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 19 1 6813 12 2 false 0.44504925959640446 0.44504925959640446 0.0 female_gonad_development GO:0008585 12133 73 19 1 163 1 2 false 0.44785276073619185 0.44785276073619185 3.313368928641239E-48 glycosyl_compound_metabolic_process GO:1901657 12133 1093 19 3 7599 17 2 false 0.4509926856748365 0.4509926856748365 0.0 vesicle_membrane GO:0012506 12133 312 19 1 9991 19 4 false 0.4530228537603572 0.4530228537603572 0.0 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 19 1 599 2 2 false 0.4533643028234985 0.4533643028234985 1.7219296535416308E-148 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 19 1 242 3 2 false 0.45380988306300024 0.45380988306300024 2.220259827778367E-49 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 19 3 1319 3 1 false 0.454027263365971 0.454027263365971 6.536050345296563E-309 regulation_of_catalytic_activity GO:0050790 12133 1692 19 3 6953 10 3 false 0.45438844785523225 0.45438844785523225 0.0 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 19 2 217 3 1 false 0.45491432381900665 0.45491432381900665 1.2933579260360868E-64 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 19 2 134 3 2 false 0.4549382275226906 0.4549382275226906 8.460684206886756E-40 positive_regulation_of_signal_transduction GO:0009967 12133 782 19 2 3650 7 5 false 0.46221357692433285 0.46221357692433285 0.0 response_to_endogenous_stimulus GO:0009719 12133 982 19 2 5200 8 1 false 0.46359241785683586 0.46359241785683586 0.0 regulation_of_phosphorylation GO:0042325 12133 845 19 1 1820 1 2 false 0.4642857142855993 0.4642857142855993 0.0 ovarian_follicle_development GO:0001541 12133 39 19 1 84 1 2 false 0.4642857142857246 0.4642857142857246 7.362290770837602E-25 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 19 3 4597 7 2 false 0.4652671351558378 0.4652671351558378 0.0 establishment_of_RNA_localization GO:0051236 12133 124 19 1 2839 14 2 false 0.4656518345012353 0.4656518345012353 1.4765023034812589E-220 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 19 1 230 3 4 false 0.47276488163630914 0.47276488163630914 2.6271911283291635E-48 purine_nucleotide_catabolic_process GO:0006195 12133 956 19 3 1223 3 3 false 0.4773053603106511 0.4773053603106511 6.80299167777575E-278 positive_regulation_of_transferase_activity GO:0051347 12133 445 19 1 2275 3 3 false 0.4796809944581198 0.4796809944581198 0.0 endosomal_part GO:0044440 12133 257 19 1 7185 18 3 false 0.48129995460106767 0.48129995460106767 0.0 RNA_processing GO:0006396 12133 601 19 3 3762 16 2 false 0.48294455401810915 0.48294455401810915 0.0 response_to_virus GO:0009615 12133 230 19 1 475 1 1 false 0.4842105263158639 0.4842105263158639 3.548520767075247E-142 DNA_repair GO:0006281 12133 368 19 2 977 4 2 false 0.48424059968543565 0.48424059968543565 3.284245924949814E-280 synapse GO:0045202 12133 368 19 1 10701 19 1 false 0.48596606428151123 0.48596606428151123 0.0 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 19 3 1202 3 3 false 0.48715393855096295 0.48715393855096295 1.616697592155103E-269 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 19 4 3771 17 4 false 0.48967975536077074 0.48967975536077074 0.0 regulation_of_kinase_activity GO:0043549 12133 654 19 1 1335 1 3 false 0.4898876404494377 0.4898876404494377 0.0 spindle_organization GO:0007051 12133 78 19 1 1776 15 3 false 0.49156576403646407 0.49156576403646407 2.2015050227101385E-138 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 19 1 417 1 4 false 0.4916067146282839 0.4916067146282839 8.022991700655629E-125 positive_regulation_of_catabolic_process GO:0009896 12133 137 19 1 3517 17 3 false 0.4918747636065762 0.4918747636065762 1.0965595914697655E-250 development_of_primary_female_sexual_characteristics GO:0046545 12133 88 19 1 178 1 2 false 0.49438202247194724 0.49438202247194724 4.419703906638309E-53 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 19 1 217 3 1 false 0.49508448540702144 0.49508448540702144 4.514459380304185E-47 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 19 4 4044 17 3 false 0.49668152548434924 0.49668152548434924 0.0 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 19 1 639 1 3 false 0.49765258215962105 0.49765258215962105 1.399157780258238E-191 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 19 1 195 2 4 false 0.5002379064234905 0.5002379064234905 1.081664723883568E-50 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 19 1 1525 4 1 false 0.5009451246996103 0.5009451246996103 1.2095302863090285E-289 regulation_of_MAP_kinase_activity GO:0043405 12133 268 19 1 533 1 3 false 0.5028142589118941 0.5028142589118941 1.0382438249699724E-159 small_molecule_metabolic_process GO:0044281 12133 2423 19 4 2877 4 1 false 0.502903145430424 0.502903145430424 0.0 cellular_protein_complex_assembly GO:0043623 12133 284 19 1 958 2 2 false 0.5052366585734948 0.5052366585734948 4.57678794545446E-252 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 19 1 7778 17 4 false 0.5074258531508116 0.5074258531508116 0.0 small_ribosomal_subunit GO:0015935 12133 60 19 5 132 10 1 false 0.5083440305371476 0.5083440305371476 4.556510204279982E-39 regulation_of_cell_death GO:0010941 12133 1062 19 2 6437 10 2 false 0.509726733814746 0.509726733814746 0.0 protein_polymerization GO:0051258 12133 145 19 1 284 1 1 false 0.5105633802817375 0.5105633802817375 7.244587792673789E-85 regulation_of_mitosis GO:0007088 12133 100 19 1 611 4 4 false 0.5117068254339328 0.5117068254339328 1.2375244614825155E-117 central_nervous_system_development GO:0007417 12133 571 19 1 2686 3 2 false 0.5119300809212266 0.5119300809212266 0.0 neuron_projection GO:0043005 12133 534 19 1 1043 1 2 false 0.5119846596357591 0.5119846596357591 5.7946905775E-313 microtubule_cytoskeleton GO:0015630 12133 734 19 1 1430 1 1 false 0.5132867132864838 0.5132867132864838 0.0 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 19 2 982 2 1 false 0.513744859042883 0.513744859042883 2.6984349291053464E-253 RNA_splicing GO:0008380 12133 307 19 2 601 3 1 false 0.5162475173540857 0.5162475173540857 4.262015823312228E-180 endosomal_transport GO:0016197 12133 133 19 1 2454 13 2 false 0.5162580121684007 0.5162580121684007 7.966947585336105E-224 dendrite GO:0030425 12133 276 19 1 534 1 1 false 0.516853932584358 0.516853932584358 6.975042602902724E-160 cytoplasmic_vesicle GO:0031410 12133 764 19 2 8540 19 3 false 0.5170946801181678 0.5170946801181678 0.0 intracellular_signal_transduction GO:0035556 12133 1813 19 4 3547 7 1 false 0.5243688983776107 0.5243688983776107 0.0 regulation_of_catabolic_process GO:0009894 12133 554 19 2 5455 17 2 false 0.5272134159150996 0.5272134159150996 0.0 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 19 3 2643 5 1 false 0.5308608691318923 0.5308608691318923 0.0 regulation_of_protein_kinase_activity GO:0045859 12133 621 19 1 1169 1 3 false 0.5312232677504198 0.5312232677504198 0.0 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 19 1 162 3 5 false 0.5320048309178562 0.5320048309178562 7.1760328941400225E-37 spindle_checkpoint GO:0031577 12133 45 19 1 202 3 1 false 0.5325033249593265 0.5325033249593265 4.3818533729449334E-46 MAP_kinase_activity GO:0004707 12133 277 19 1 520 1 2 false 0.5326923076922037 0.5326923076922037 2.5282679507054518E-155 regulation_of_programmed_cell_death GO:0043067 12133 1031 19 2 1410 2 2 false 0.5345222455445995 0.5345222455445995 0.0 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 19 3 86 3 2 false 0.5348837209302556 0.5348837209302556 1.0344828145516245E-17 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 19 3 81 3 2 false 0.536333802156596 0.536333802156596 1.2278945146862784E-16 membrane_invagination GO:0010324 12133 411 19 2 784 3 1 false 0.5363699702770965 0.5363699702770965 8.658368437912315E-235 nuclear_speck GO:0016607 12133 147 19 1 272 1 1 false 0.5404411764705604 0.5404411764705604 6.6218564870724965E-81 regulation_of_apoptotic_process GO:0042981 12133 1019 19 2 1381 2 2 false 0.5443136143732132 0.5443136143732132 0.0 activating_transcription_factor_binding GO:0033613 12133 294 19 2 715 4 1 false 0.5443200193340662 0.5443200193340662 1.6086726333731214E-209 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 19 1 254 2 3 false 0.5476331268866782 0.5476331268866782 3.7262148804586973E-69 response_to_biotic_stimulus GO:0009607 12133 494 19 1 5200 8 1 false 0.5502792708631045 0.5502792708631045 0.0 cellular_amino_acid_metabolic_process GO:0006520 12133 337 19 1 7342 17 3 false 0.5505242162095334 0.5505242162095334 0.0 activation_of_MAPK_activity GO:0000187 12133 158 19 1 286 1 2 false 0.5524475524475345 0.5524475524475345 8.207976102051858E-85 mitosis GO:0007067 12133 326 19 2 953 5 2 false 0.5566287899690404 0.5566287899690404 4.8424843971573165E-265 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 19 1 5157 9 3 false 0.5589424407336394 0.5589424407336394 0.0 chromatin GO:0000785 12133 287 19 1 512 1 1 false 0.5605468749999285 0.5605468749999285 9.050120143931621E-152 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 19 1 2035 5 3 false 0.5652723628467906 0.5652723628467906 0.0 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 19 1 53 1 2 false 0.5660377358490526 0.5660377358490526 1.6040955778771873E-15 cardiovascular_system_development GO:0072358 12133 655 19 1 2686 3 2 false 0.5678294204810143 0.5678294204810143 0.0 circulatory_system_development GO:0072359 12133 655 19 1 2686 3 1 false 0.5678294204810143 0.5678294204810143 0.0 regulation_of_transferase_activity GO:0051338 12133 667 19 1 2708 3 2 false 0.572017816735531 0.572017816735531 0.0 ion_transmembrane_transport GO:0034220 12133 556 19 1 970 1 2 false 0.5731958762885236 0.5731958762885236 1.3121997139332702E-286 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 19 2 1546 4 3 false 0.5741323054626983 0.5741323054626983 0.0 vesicle GO:0031982 12133 834 19 2 7980 18 1 false 0.5751090484727994 0.5751090484727994 0.0 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 19 5 645 5 1 false 0.5768411839841754 0.5768411839841754 7.3138241320053254E-93 cellular_process GO:0009987 12133 9675 19 18 10446 19 1 false 0.5856283776616834 0.5856283776616834 0.0 regulatory_region_DNA_binding GO:0000975 12133 1169 19 2 2091 3 2 false 0.588223730942481 0.588223730942481 0.0 purine_nucleoside_metabolic_process GO:0042278 12133 1054 19 3 1257 3 2 false 0.589272371014592 0.589272371014592 1.399683863089717E-240 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 19 2 630 5 2 false 0.5918985760587971 0.5918985760587971 4.4826406352842784E-178 activation_of_protein_kinase_activity GO:0032147 12133 247 19 1 417 1 1 false 0.5923261390887407 0.5923261390887407 9.475379918718814E-122 ribosome_biogenesis GO:0042254 12133 144 19 1 243 1 1 false 0.5925925925925675 0.5925925925925675 8.984879194471426E-71 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 19 1 3447 4 2 false 0.5927132874822924 0.5927132874822924 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 19 4 5303 17 3 false 0.5927902280733772 0.5927902280733772 0.0 sex_differentiation GO:0007548 12133 202 19 1 340 1 1 false 0.5941176470587681 0.5941176470587681 4.342696063294865E-99 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 19 2 136 2 2 false 0.5947712418300675 0.5947712418300675 2.4301849830786213E-31 signaling GO:0023052 12133 3878 19 7 10446 19 1 false 0.5957668059404856 0.5957668059404856 0.0 steroid_hormone_receptor_binding GO:0035258 12133 62 19 1 104 1 1 false 0.5961538461538246 0.5961538461538246 4.2931773052216616E-30 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 19 2 90 2 3 false 0.6029962546816539 0.6029962546816539 1.9615250672171495E-20 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 19 10 106 10 2 false 0.6031531047748091 0.6031531047748091 9.867686559172291E-9 regulation_of_organelle_organization GO:0033043 12133 519 19 1 2487 4 2 false 0.6081492989638653 0.6081492989638653 0.0 cytoplasmic_vesicle_part GO:0044433 12133 366 19 1 7185 18 3 false 0.6102435419109922 0.6102435419109922 0.0 response_to_stress GO:0006950 12133 2540 19 4 5200 8 1 false 0.611290965976061 0.611290965976061 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 19 1 701 1 2 false 0.6119828815976278 0.6119828815976278 1.5434745144062482E-202 androgen_receptor_binding GO:0050681 12133 38 19 1 62 1 1 false 0.6129032258064553 0.6129032258064553 1.0311688046013243E-17 mitotic_spindle_checkpoint GO:0071174 12133 38 19 1 140 3 2 false 0.6163814290182628 0.6163814290182628 3.73538767395573E-35 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 19 1 768 1 1 false 0.6210937499998362 0.6210937499998362 1.6461815804374103E-220 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 19 4 3547 7 1 false 0.622778203734673 0.622778203734673 0.0 MAPK_cascade GO:0000165 12133 502 19 1 806 1 1 false 0.6228287841190995 0.6228287841190995 3.7900857366173457E-231 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 19 2 10311 19 3 false 0.6236656295008882 0.6236656295008882 0.0 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 19 2 129 2 1 false 0.6239098837209381 0.6239098837209381 2.104544859412626E-28 nucleobase-containing_compound_transport GO:0015931 12133 135 19 1 1584 11 2 false 0.6258602769911533 0.6258602769911533 1.0378441909200412E-199 in_utero_embryonic_development GO:0001701 12133 295 19 1 471 1 1 false 0.6263269639064891 0.6263269639064891 1.719393530200133E-134 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 19 1 1399 2 3 false 0.6266646623730255 0.6266646623730255 0.0 lipid_binding GO:0008289 12133 571 19 1 8962 15 1 false 0.6277925299152654 0.6277925299152654 0.0 negative_regulation_of_apoptotic_process GO:0043066 12133 537 19 1 1377 2 3 false 0.6280463089635778 0.6280463089635778 0.0 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 19 1 178 1 1 false 0.629213483146089 0.629213483146089 1.7238002808689451E-50 protein_folding GO:0006457 12133 183 19 1 3038 16 1 false 0.6308609042870069 0.6308609042870069 1.582632936584301E-299 RNA_localization GO:0006403 12133 131 19 1 1642 12 1 false 0.6325697596698227 0.6325697596698227 1.0675246049472868E-197 actin_filament-based_process GO:0030029 12133 431 19 1 7541 17 1 false 0.6327044101017125 0.6327044101017125 0.0 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 19 8 8688 18 3 false 0.6329770895324851 0.6329770895324851 0.0 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 19 4 7461 17 2 false 0.6356259068470227 0.6356259068470227 0.0 ncRNA_processing GO:0034470 12133 186 19 1 649 3 2 false 0.6375902203515856 0.6375902203515856 4.048832162241149E-168 egress_of_virus_within_host_cell GO:0046788 12133 11 19 1 28 2 2 false 0.640211640211643 0.640211640211643 4.656755228837597E-8 regulation_of_protein_metabolic_process GO:0051246 12133 1388 19 4 5563 17 3 false 0.6455491708240496 0.6455491708240496 0.0 embryo_development GO:0009790 12133 768 19 1 3347 4 3 false 0.6476692952336565 0.6476692952336565 0.0 purine_nucleoside_catabolic_process GO:0006152 12133 939 19 3 1085 3 3 false 0.6479187446689437 0.6479187446689437 2.1746006434797338E-185 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 19 1 2776 4 3 false 0.6496955754864564 0.6496955754864564 0.0 anatomical_structure_development GO:0048856 12133 3099 19 4 3447 4 1 false 0.6531850279989884 0.6531850279989884 0.0 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 19 1 971 12 2 false 0.655297178481701 0.655297178481701 1.7939571902377886E-121 endosome GO:0005768 12133 455 19 1 8213 19 2 false 0.6617950556283101 0.6617950556283101 0.0 cytoplasmic_vesicle_membrane GO:0030659 12133 302 19 1 719 2 3 false 0.6639715482278123 0.6639715482278123 1.2351303462379864E-211 PML_body_organization GO:0030578 12133 4 19 1 6 1 1 false 0.6666666666666662 0.6666666666666662 0.06666666666666664 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 19 10 181 10 1 false 0.6671161053196255 0.6671161053196255 8.905994863592909E-13 protein_complex_biogenesis GO:0070271 12133 746 19 2 1525 4 1 false 0.6713326585001054 0.6713326585001054 0.0 cellular_component_organization GO:0016043 12133 3745 19 16 3839 16 1 false 0.6720439672196483 0.6720439672196483 4.153510440731863E-191 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 19 1 1079 2 3 false 0.6721815189972706 0.6721815189972706 5.98264E-319 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 19 1 587 2 2 false 0.6727735753615924 0.6727735753615924 2.854325455984618E-173 acid-amino_acid_ligase_activity GO:0016881 12133 351 19 5 379 5 1 false 0.6798574075111385 0.6798574075111385 5.324332733169013E-43 negative_regulation_of_gene_expression GO:0010629 12133 817 19 3 3906 16 3 false 0.6815411054593491 0.6815411054593491 0.0 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 19 2 185 2 1 false 0.6831962397181021 0.6831962397181021 1.2806047113744547E-36 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 19 3 4429 16 3 false 0.6843079658726056 0.6843079658726056 0.0 membrane_organization GO:0061024 12133 787 19 3 3745 16 1 false 0.6849688178764648 0.6849688178764648 0.0 ribonucleoside_catabolic_process GO:0042454 12133 946 19 3 1073 3 2 false 0.6850321606152967 0.6850321606152967 9.25790942536024E-169 nuclear_import GO:0051170 12133 203 19 1 2389 13 3 false 0.6857172751291764 0.6857172751291764 7.452348105569065E-301 regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032434 12133 57 19 1 227 4 2 false 0.6882571179811336 0.6882571179811336 4.5524072103258975E-55 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 19 3 1054 3 2 false 0.6911364851424968 0.6911364851424968 2.3625686453162704E-163 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 19 3 1060 3 3 false 0.6948971467392391 0.6948971467392391 8.715047292960447E-163 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 19 3 4298 16 4 false 0.6950823341096071 0.6950823341096071 0.0 organelle_organization GO:0006996 12133 2031 19 4 7663 17 2 false 0.6981857997391462 0.6981857997391462 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 19 1 1014 1 1 false 0.6992110453650483 0.6992110453650483 1.8231541307779663E-268 neuron_part GO:0097458 12133 612 19 1 9983 19 1 false 0.6997479250744474 0.6997479250744474 0.0 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 19 3 5558 17 3 false 0.6999787517570852 0.6999787517570852 0.0 growth GO:0040007 12133 646 19 1 10446 19 1 false 0.7029867527151572 0.7029867527151572 0.0 protein_import GO:0017038 12133 225 19 1 2509 13 2 false 0.7060956567154071 0.7060956567154071 0.0 ncRNA_metabolic_process GO:0034660 12133 258 19 1 3294 15 1 false 0.7065780903265679 0.7065780903265679 0.0 DNA_integrity_checkpoint GO:0031570 12133 130 19 2 202 3 1 false 0.7104182059996653 0.7104182059996653 1.23666756413938E-56 single_organism_reproductive_process GO:0044702 12133 539 19 1 8107 18 2 false 0.71053737893862 0.71053737893862 0.0 receptor_binding GO:0005102 12133 918 19 1 6397 8 1 false 0.7106117928731726 0.7106117928731726 0.0 cellular_protein_complex_disassembly GO:0043624 12133 149 19 10 154 10 1 false 0.7115576240952446 0.7115576240952446 1.4793035521715585E-9 organophosphate_metabolic_process GO:0019637 12133 1549 19 3 7521 17 2 false 0.7115711255420335 0.7115711255420335 0.0 immune_response-activating_signal_transduction GO:0002757 12133 299 19 2 352 2 2 false 0.721170033669993 0.721170033669993 2.8561568566531905E-64 regulation_of_metabolic_process GO:0019222 12133 4469 19 8 9189 18 2 false 0.7219267487077425 0.7219267487077425 0.0 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 19 2 2528 5 3 false 0.7286047438260719 0.7286047438260719 0.0 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 19 2 381 4 2 false 0.7287467416803275 0.7287467416803275 8.855041133991382E-114 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 19 1 1779 1 1 false 0.7329960652055553 0.7329960652055553 0.0 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 19 3 7451 17 1 false 0.7337168602024519 0.7337168602024519 0.0 actin_cytoskeleton_organization GO:0030036 12133 373 19 1 768 2 2 false 0.7357976151671828 0.7357976151671828 3.0657297438498186E-230 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 19 3 3453 15 4 false 0.7366166768649272 0.7366166768649272 0.0 catalytic_activity GO:0003824 12133 4901 19 8 10478 19 2 false 0.7367742331932193 0.7367742331932193 0.0 purine_nucleotide_metabolic_process GO:0006163 12133 1208 19 3 1337 3 2 false 0.7373987228449017 0.7373987228449017 1.5771526523631757E-183 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 19 1 129 2 1 false 0.7401889534883652 0.7401889534883652 2.169508265339551E-38 developmental_process_involved_in_reproduction GO:0003006 12133 340 19 1 3959 15 2 false 0.7406051684501891 0.7406051684501891 0.0 intracellular_organelle_lumen GO:0070013 12133 2919 19 8 5320 16 2 false 0.7409362907405672 0.7409362907405672 0.0 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 19 3 5151 17 4 false 0.7419377627028372 0.7419377627028372 0.0 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 19 3 3780 16 4 false 0.7429553695619581 0.7429553695619581 0.0 organelle_lumen GO:0043233 12133 2968 19 8 5401 16 2 false 0.7431671819906223 0.7431671819906223 0.0 positive_regulation_of_cell_proliferation GO:0008284 12133 558 19 1 3155 7 3 false 0.7443263044204581 0.7443263044204581 0.0 enzyme_binding GO:0019899 12133 1005 19 1 6397 8 1 false 0.745414508318562 0.745414508318562 0.0 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 19 1 129 2 1 false 0.7480620155038853 0.7480620155038853 2.1037655906323275E-38 regulation_of_primary_metabolic_process GO:0080090 12133 3921 19 8 7507 17 2 false 0.7487281432515276 0.7487281432515276 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 19 5 400 5 2 false 0.7525272191527608 0.7525272191527608 1.150456419433401E-36 protein_kinase_activity GO:0004672 12133 1014 19 1 1347 1 3 false 0.7527839643658618 0.7527839643658618 0.0 large_ribosomal_subunit GO:0015934 12133 73 19 5 132 10 1 false 0.75303469082711 0.75303469082711 5.5437540818743186E-39 single_fertilization GO:0007338 12133 49 19 1 65 1 1 false 0.753846153846139 0.753846153846139 1.543100485620412E-15 ribonucleotide_metabolic_process GO:0009259 12133 1202 19 3 1318 3 2 false 0.7583534146640842 0.7583534146640842 7.680938106405399E-170 kinase_activity GO:0016301 12133 1174 19 1 1546 1 2 false 0.7593790426910867 0.7593790426910867 0.0 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 19 8 6094 17 2 false 0.7604944060801577 0.7604944060801577 0.0 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 19 1 1813 4 1 false 0.7625776315393573 0.7625776315393573 0.0 negative_regulation_of_cell_death GO:0060548 12133 567 19 1 3054 7 3 false 0.7628815459555723 0.7628815459555723 0.0 nucleoside_binding GO:0001882 12133 1639 19 4 4455 13 3 false 0.7653713768633407 0.7653713768633407 0.0 JNK_cascade GO:0007254 12133 159 19 1 207 1 1 false 0.7681159420289673 0.7681159420289673 3.1556682987155503E-48 carboxylic_acid_metabolic_process GO:0019752 12133 614 19 1 7453 17 2 false 0.7685097974411547 0.7685097974411547 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 19 2 147 2 1 false 0.7693597987139774 0.7693597987139774 1.843896992838607E-23 nucleotide_binding GO:0000166 12133 1997 19 5 2103 5 2 false 0.7719411355355333 0.7719411355355333 1.0169073992212018E-181 translation_elongation_factor_activity GO:0003746 12133 22 19 1 180 11 2 false 0.7719938222090688 0.7719938222090688 1.0368938565383413E-28 regulation_of_cellular_component_organization GO:0051128 12133 1152 19 2 7336 17 2 false 0.7719988806677414 0.7719988806677414 0.0 enzyme_regulator_activity GO:0030234 12133 771 19 1 10257 19 3 false 0.773742327978961 0.773742327978961 0.0 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 19 2 185 2 1 false 0.7757344300823621 0.7757344300823621 5.464989090238489E-29 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 19 3 3847 15 4 false 0.7763431021584491 0.7763431021584491 0.0 transport GO:0006810 12133 2783 19 14 2833 14 1 false 0.7788994684404359 0.7788994684404359 1.147202604491021E-108 nucleoside_phosphate_binding GO:1901265 12133 1998 19 5 4407 13 2 false 0.779780708577561 0.779780708577561 0.0 cellular_macromolecular_complex_assembly GO:0034622 12133 517 19 1 973 2 1 false 0.7806199484857734 0.7806199484857734 3.312522477266262E-291 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 19 1 3702 8 3 false 0.7812930489867882 0.7812930489867882 0.0 multicellular_organism_reproduction GO:0032504 12133 482 19 1 4643 14 2 false 0.7849207940389316 0.7849207940389316 0.0 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 19 3 1007 3 2 false 0.7849643103887629 0.7849643103887629 1.4040993054667365E-118 T_cell_receptor_signaling_pathway GO:0050852 12133 88 19 1 112 1 1 false 0.7857142857143178 0.7857142857143178 5.828412725788921E-25 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 19 2 71 2 3 false 0.785915492957749 0.785915492957749 9.399268641403064E-11 response_to_chemical_stimulus GO:0042221 12133 2369 19 3 5200 8 1 false 0.7894852492798239 0.7894852492798239 0.0 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 19 3 1006 3 2 false 0.789857749500738 0.789857749500738 2.1893990019353197E-116 purine_nucleotide_binding GO:0017076 12133 1650 19 4 1997 5 1 false 0.7901082974492065 0.7901082974492065 0.0 purine-containing_compound_metabolic_process GO:0072521 12133 1232 19 3 5323 17 5 false 0.7902942195978413 0.7902942195978413 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 19 5 351 5 1 false 0.7908466482074769 0.7908466482074769 5.577217121688537E-28 ribonucleotide_binding GO:0032553 12133 1651 19 4 1997 5 1 false 0.7910901673505866 0.7910901673505866 0.0 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 19 1 312 1 1 false 0.7916666666666485 0.7916666666666485 8.216510305576978E-69 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 19 1 1350 3 4 false 0.7922198539083825 0.7922198539083825 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 19 3 4103 16 3 false 0.7924125172485753 0.7924125172485753 0.0 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 19 1 129 2 1 false 0.7927567829457374 0.7927567829457374 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 19 1 129 2 1 false 0.7927567829457374 0.7927567829457374 3.3394798770258706E-38 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 19 3 1002 3 3 false 0.7967858728093028 0.7967858728093028 5.68242981185093E-113 interaction_with_host GO:0051701 12133 387 19 3 417 3 2 false 0.7988799414594865 0.7988799414594865 1.9217516081652173E-46 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 19 1 129 2 1 false 0.7997819767441774 0.7997819767441774 4.0186961232005657E-38 spindle_assembly_checkpoint GO:0071173 12133 36 19 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 chromosomal_part GO:0044427 12133 512 19 1 5337 16 2 false 0.8013157109507044 0.8013157109507044 0.0 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 19 1 361 4 1 false 0.8030227978829908 0.8030227978829908 4.560830022372086E-99 cell_cycle_checkpoint GO:0000075 12133 202 19 3 217 3 1 false 0.8057966872670375 0.8057966872670375 1.925703524045096E-23 organic_acid_metabolic_process GO:0006082 12133 676 19 1 7326 17 2 false 0.8075093805860201 0.8075093805860201 0.0 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 19 3 5657 17 2 false 0.8097646213383504 0.8097646213383504 0.0 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 19 1 5027 17 3 false 0.8134345900242378 0.8134345900242378 0.0 response_to_stimulus GO:0050896 12133 5200 19 8 10446 19 1 false 0.8154554131353001 0.8154554131353001 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 19 1 6358 10 2 false 0.8192581574177316 0.8192581574177316 0.0 transmembrane_transport GO:0055085 12133 728 19 1 7606 17 2 false 0.8195419455689681 0.8195419455689681 0.0 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 19 2 803 3 1 false 0.8207256565794947 0.8207256565794947 1.0286714317927864E-202 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 19 1 309 2 2 false 0.8210608162062534 0.8210608162062534 7.558729588417702E-91 programmed_cell_death GO:0012501 12133 1385 19 2 1525 2 1 false 0.8247665763094012 0.8247665763094012 2.142172117700311E-202 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 19 1 129 2 1 false 0.82667151162791 0.82667151162791 1.1512773005265922E-37 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 19 3 4582 16 3 false 0.8274905659271853 0.8274905659271853 0.0 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 19 8 6638 17 2 false 0.8275412761116895 0.8275412761116895 0.0 regulation_of_cellular_catabolic_process GO:0031329 12133 494 19 1 5000 17 3 false 0.8299165559223739 0.8299165559223739 0.0 membrane-bounded_vesicle GO:0031988 12133 762 19 2 834 2 1 false 0.8346964685154482 0.8346964685154482 6.820230733401612E-106 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 19 3 4456 16 4 false 0.8348825085944829 0.8348825085944829 0.0 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 19 1 1304 1 1 false 0.8351226993861972 0.8351226993861972 1.004636319027547E-252 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 19 2 165 2 2 false 0.8370288248337823 0.8370288248337823 1.3866478491946915E-20 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 19 1 1730 4 2 false 0.8380591297076303 0.8380591297076303 0.0 system_development GO:0048731 12133 2686 19 3 3304 4 2 false 0.8388615216619272 0.8388615216619272 0.0 multicellular_organismal_development GO:0007275 12133 3069 19 3 4373 5 2 false 0.8394231707898431 0.8394231707898431 0.0 organ_development GO:0048513 12133 1929 19 2 3099 4 2 false 0.8458449591160604 0.8458449591160604 0.0 organelle_membrane GO:0031090 12133 1619 19 2 9319 18 3 false 0.8460796378652704 0.8460796378652704 0.0 single_organism_signaling GO:0044700 12133 3878 19 7 8052 18 2 false 0.8471740135684309 0.8471740135684309 0.0 interphase GO:0051325 12133 233 19 2 253 2 1 false 0.8478574565529252 0.8478574565529252 4.555981744751407E-30 nuclear_hormone_receptor_binding GO:0035257 12133 104 19 1 122 1 1 false 0.8524590163934733 0.8524590163934733 6.677251530520905E-22 regulation_of_cellular_process GO:0050794 12133 6304 19 10 9757 18 2 false 0.8530531646544686 0.8530531646544686 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 19 1 129 2 1 false 0.8575581395348872 0.8575581395348872 8.751505837166389E-37 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 19 3 3972 16 4 false 0.8581011493972437 0.8581011493972437 0.0 cell_projection GO:0042995 12133 976 19 1 9983 19 1 false 0.858663090880346 0.858663090880346 0.0 nuclear_division GO:0000280 12133 326 19 2 351 2 1 false 0.8624338624341342 0.8624338624341342 8.671827254018066E-39 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 19 7 4544 15 3 false 0.8662015280186413 0.8662015280186413 0.0 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 19 5 3120 7 4 false 0.868852956464471 0.868852956464471 0.0 structural_constituent_of_cytoskeleton GO:0005200 12133 88 19 1 526 11 1 false 0.8693490723513413 0.8693490723513413 1.4915391741340796E-102 nuclear_export GO:0051168 12133 116 19 1 688 11 2 false 0.8709485728102574 0.8709485728102574 6.892155989004194E-135 molecular_transducer_activity GO:0060089 12133 1070 19 1 10257 19 1 false 0.8769534319659029 0.8769534319659029 0.0 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 19 2 723 4 2 false 0.8794341834933148 0.8794341834933148 2.0953844092707462E-201 cell_communication GO:0007154 12133 3962 19 7 7541 17 1 false 0.8815381487992417 0.8815381487992417 0.0 regulation_of_protein_localization GO:0032880 12133 349 19 1 2148 12 2 false 0.8815967246951557 0.8815967246951557 0.0 hydrolase_activity GO:0016787 12133 2556 19 3 4901 8 1 false 0.8821106340130023 0.8821106340130023 0.0 death GO:0016265 12133 1528 19 2 8052 18 1 false 0.8821618173693886 0.8821618173693886 0.0 nervous_system_development GO:0007399 12133 1371 19 1 2686 3 1 false 0.8827931391823057 0.8827931391823057 0.0 macromolecule_modification GO:0043412 12133 2461 19 5 6052 17 1 false 0.8854106223758944 0.8854106223758944 0.0 regulation_of_biological_process GO:0050789 12133 6622 19 10 10446 19 2 false 0.8861423490929228 0.8861423490929228 0.0 cell_death GO:0008219 12133 1525 19 2 7542 17 2 false 0.886205312301958 0.886205312301958 0.0 intrinsic_to_membrane GO:0031224 12133 2375 19 2 2995 3 1 false 0.8892774043792759 0.8892774043792759 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 19 2 214 2 1 false 0.8907463472423881 0.8907463472423881 7.108512362452622E-20 transcription_cofactor_activity GO:0003712 12133 456 19 2 482 2 2 false 0.8949198160815699 0.8949198160815699 1.3948726648763881E-43 cellular_response_to_stimulus GO:0051716 12133 4236 19 7 7871 17 2 false 0.9014492064431283 0.9014492064431283 0.0 'de_novo'_posttranslational_protein_folding GO:0051084 12133 46 19 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 nitrogen_compound_transport GO:0071705 12133 428 19 1 2783 14 1 false 0.9040383149631686 0.9040383149631686 0.0 intracellular_protein_kinase_cascade GO:0007243 12133 806 19 1 1813 4 1 false 0.9050763994234384 0.9050763994234384 0.0 regulation_of_protein_phosphorylation GO:0001932 12133 787 19 1 1444 3 3 false 0.9060467680545976 0.9060467680545976 0.0 single-organism_metabolic_process GO:0044710 12133 2877 19 4 8027 17 1 false 0.9095432047291644 0.9095432047291644 0.0 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 19 1 2780 4 2 false 0.9119584330715285 0.9119584330715285 0.0 developmental_process GO:0032502 12133 3447 19 4 10446 19 1 false 0.9170396590553079 0.9170396590553079 0.0 binding GO:0005488 12133 8962 19 15 10257 19 1 false 0.9183626570991421 0.9183626570991421 0.0 nucleic_acid_transport GO:0050657 12133 124 19 1 135 1 1 false 0.9185185185185545 0.9185185185185545 2.2345648964967124E-16 protein_processing GO:0016485 12133 113 19 1 123 1 1 false 0.918699186991829 0.918699186991829 6.665856545071852E-15 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 19 2 73 2 1 false 0.9189497716895059 0.9189497716895059 1.607820438613435E-5 signal_transducer_activity GO:0004871 12133 1070 19 1 3547 7 2 false 0.9192130215358888 0.9192130215358888 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 19 3 1180 14 1 false 0.9212077419940692 0.9212077419940692 0.0 female_pregnancy GO:0007565 12133 126 19 1 712 13 2 false 0.9223637395487243 0.9223637395487243 1.1918411623730802E-143 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 19 5 378 5 1 false 0.9227177891663332 0.9227177891663332 2.5686196448553377E-13 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 19 2 78 2 1 false 0.9240759240759076 0.9240759240759076 1.3144749986854762E-5 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 19 1 6622 10 1 false 0.9281549579764399 0.9281549579764399 0.0 anatomical_structure_morphogenesis GO:0009653 12133 1664 19 1 3447 4 2 false 0.9285283120251386 0.9285283120251386 0.0 biological_regulation GO:0065007 12133 6908 19 10 10446 19 1 false 0.9286319795123902 0.9286319795123902 0.0 chromosome GO:0005694 12133 592 19 1 3226 13 1 false 0.9287144591790313 0.9287144591790313 0.0 nucleolus GO:0005730 12133 1357 19 3 4208 16 3 false 0.9297991574227742 0.9297991574227742 0.0 cellular_component_biogenesis GO:0044085 12133 1525 19 4 3839 16 1 false 0.9324088870713945 0.9324088870713945 0.0 membrane_part GO:0044425 12133 2995 19 3 10701 19 2 false 0.9333494439690996 0.9333494439690996 0.0 nucleoplasm_part GO:0044451 12133 805 19 1 2767 8 2 false 0.9363627106794351 0.9363627106794351 0.0 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 19 3 1218 3 2 false 0.9372674542586665 0.9372674542586665 3.12960829510125E-54 ion_binding GO:0043167 12133 4448 19 5 8962 15 1 false 0.9374731615047296 0.9374731615047296 0.0 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 19 7 5532 17 4 false 0.9379263634177457 0.9379263634177457 0.0 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 19 1 5183 10 2 false 0.94107822821005 0.94107822821005 0.0 mitochondrion GO:0005739 12133 1138 19 1 8213 19 2 false 0.9414116851477297 0.9414116851477297 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 19 4 7256 17 1 false 0.9420425424592596 0.9420425424592596 0.0 nucleoside-triphosphatase_activity GO:0017111 12133 1059 19 3 1080 3 1 false 0.9427415623200115 0.9427415623200115 1.2343281293318376E-44 phosphorylation GO:0016310 12133 1421 19 1 2776 4 1 false 0.943363856661895 0.943363856661895 0.0 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 19 3 1072 3 2 false 0.947717266568648 0.947717266568648 3.811291228230986E-41 regulation_of_localization GO:0032879 12133 1242 19 1 7621 17 2 false 0.9515738965213312 0.9515738965213312 0.0 integral_to_membrane GO:0016021 12133 2318 19 2 2375 2 1 false 0.952566133110128 0.952566133110128 3.0839384482043954E-116 purine_ribonucleotide_binding GO:0032555 12133 1641 19 4 1660 4 2 false 0.9549569007756471 0.9549569007756471 8.870449707822982E-45 protein_phosphorylation GO:0006468 12133 1195 19 1 2577 5 2 false 0.9557912279146975 0.9557912279146975 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 19 4 2805 4 1 false 0.959260743642875 0.959260743642875 1.0460685646312495E-69 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 19 2 2849 10 1 false 0.959798404695139 0.959798404695139 0.0 cell_proliferation GO:0008283 12133 1316 19 1 8052 18 1 false 0.9598805632853602 0.9598805632853602 0.0 protein_binding GO:0005515 12133 6397 19 8 8962 15 1 false 0.9617627882566053 0.9617627882566053 0.0 cytoskeletal_part GO:0044430 12133 1031 19 1 5573 16 2 false 0.9622947087919016 0.9622947087919016 0.0 cellular_component_assembly GO:0022607 12133 1392 19 3 3836 16 2 false 0.9641321896463474 0.9641321896463474 0.0 vesicle-mediated_transport GO:0016192 12133 895 19 2 2783 14 1 false 0.966917671356314 0.966917671356314 0.0 ribonucleoside_metabolic_process GO:0009119 12133 1071 19 3 1083 3 1 false 0.9670959006082696 0.9670959006082696 1.9559437642804265E-28 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 19 5 672 14 1 false 0.9693137412280293 0.9693137412280293 6.935915883902889E-199 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 19 3 1014 3 1 false 0.9706763636218662 0.9706763636218662 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 19 3 1014 3 1 false 0.9706763636218662 0.9706763636218662 3.301546202575714E-24 transferase_activity GO:0016740 12133 1779 19 1 4901 8 1 false 0.9729747405403703 0.9729747405403703 0.0 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 19 2 149 2 1 false 0.9732450571376651 0.9732450571376651 9.06947215672054E-5 single-organism_developmental_process GO:0044767 12133 2776 19 3 8064 18 2 false 0.9736727915273163 0.9736727915273163 0.0 protein_ubiquitination GO:0016567 12133 548 19 4 578 5 1 false 0.9763614600610195 0.9763614600610195 7.913703273197485E-51 cell_periphery GO:0071944 12133 2667 19 2 9983 19 1 false 0.978495418982811 0.978495418982811 0.0 metal_ion_binding GO:0046872 12133 2699 19 1 2758 1 1 false 0.9786076867315662 0.9786076867315662 2.6200760259069314E-123 multicellular_organismal_process GO:0032501 12133 4223 19 4 10446 19 1 false 0.979048217506849 0.979048217506849 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 19 2 1225 3 2 false 0.9793779817736419 0.9793779817736419 5.928244845001387E-155 viral_reproduction GO:0016032 12133 633 19 13 634 13 1 false 0.9794952681389355 0.9794952681389355 0.0015772870662463625 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 19 2 199 2 1 false 0.9799502563321717 0.9799502563321717 5.075884472869322E-5 purine_nucleoside_binding GO:0001883 12133 1631 19 4 1639 4 1 false 0.9806007488464052 0.9806007488464052 7.876250956196666E-22 membrane GO:0016020 12133 4398 19 4 10701 19 1 false 0.9817782955231243 0.9817782955231243 0.0 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 19 3 1007 3 2 false 0.9822138475969335 0.9822138475969335 7.008686204750717E-16 apoptotic_process GO:0006915 12133 1373 19 2 1385 2 1 false 0.9827403434810396 0.9827403434810396 1.0085392941984968E-29 nuclear_transport GO:0051169 12133 331 19 1 1148 12 1 false 0.98351213510373 0.98351213510373 1.3196682196913852E-298 protein_import_into_nucleus GO:0006606 12133 200 19 1 690 12 5 false 0.9841883230033114 0.9841883230033114 1.1794689955817937E-179 regulation_of_biosynthetic_process GO:0009889 12133 3012 19 5 5483 16 2 false 0.9849752457332772 0.9849752457332772 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 19 4 1635 4 2 false 0.9853883665513075 0.9853883665513075 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 19 4 1639 4 1 false 0.9854238628325719 0.9854238628325719 3.7483303336303164E-17 regulation_of_gene_expression GO:0010468 12133 2935 19 7 4361 16 2 false 0.9863436653426502 0.9863436653426502 0.0 oxoacid_metabolic_process GO:0043436 12133 667 19 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 chordate_embryonic_development GO:0043009 12133 471 19 1 477 1 1 false 0.9874213836479633 0.9874213836479633 6.308586670641318E-14 nucleocytoplasmic_transport GO:0006913 12133 327 19 1 331 1 1 false 0.9879154078549209 0.9879154078549209 2.036102168267257E-9 organophosphate_catabolic_process GO:0046434 12133 1000 19 3 2495 17 2 false 0.9881068467135398 0.9881068467135398 0.0 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 19 3 1085 3 1 false 0.9889706819254394 0.9889706819254394 1.7413918354446858E-11 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 19 3 2517 17 2 false 0.9905382278990115 0.9905382278990115 0.0 sexual_reproduction GO:0019953 12133 407 19 1 1345 13 1 false 0.9910001368982111 0.9910001368982111 0.0 cation_binding GO:0043169 12133 2758 19 1 4448 5 1 false 0.9921111396749229 0.9921111396749229 0.0 protein_localization_to_nucleus GO:0034504 12133 233 19 2 516 12 1 false 0.9924974447292716 0.9924974447292716 1.4955266190313754E-153 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 19 3 2643 17 2 false 0.9934864227112654 0.9934864227112654 0.0 glycosyl_compound_catabolic_process GO:1901658 12133 956 19 3 2175 17 2 false 0.9949321312032857 0.9949321312032857 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 19 5 4972 16 3 false 0.9952762460738226 0.9952762460738226 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 19 3 1319 3 1 false 0.9954545506831779 0.9954545506831779 1.1504554077729292E-6 ATP_binding GO:0005524 12133 1212 19 1 1638 4 3 false 0.9954726807529751 0.9954726807529751 0.0 adenyl_ribonucleotide_binding GO:0032559 12133 1231 19 1 1645 4 2 false 0.996031640588845 0.996031640588845 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 19 1 1650 4 1 false 0.9960414120449983 0.9960414120449983 0.0 plasma_membrane GO:0005886 12133 2594 19 1 10252 19 3 false 0.9961062206213881 0.9961062206213881 0.0 ion_transport GO:0006811 12133 833 19 1 2323 13 1 false 0.9969479496803716 0.9969479496803716 0.0 single-multicellular_organism_process GO:0044707 12133 4095 19 4 8057 18 2 false 0.9969625232990504 0.9969625232990504 0.0 pyrophosphatase_activity GO:0016462 12133 1080 19 3 1081 3 1 false 0.997224791858996 0.997224791858996 9.250693802031629E-4 virus-host_interaction GO:0019048 12133 355 19 3 588 12 2 false 0.9976381724917719 0.9976381724917719 1.0104535019427035E-170 multicellular_organismal_reproductive_process GO:0048609 12133 477 19 1 1275 13 2 false 0.9978203447449614 0.9978203447449614 0.0 purine-containing_compound_catabolic_process GO:0072523 12133 959 19 3 1651 13 6 false 0.9979921154649212 0.9979921154649212 0.0 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 19 5 4395 16 3 false 0.9985171594046146 0.9985171594046146 0.0 transcription,_DNA-dependent GO:0006351 12133 2643 19 5 4063 16 3 false 0.9987427652232893 0.9987427652232893 0.0 protein_targeting_to_nucleus GO:0044744 12133 200 19 1 443 11 1 false 0.9987814760478192 0.9987814760478192 9.352491047681514E-132 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 19 3 1587 13 3 false 0.9990790659789197 0.9990790659789197 0.0 response_to_other_organism GO:0051707 12133 475 19 1 1194 14 2 false 0.999216470733574 0.999216470733574 0.0 DNA_binding GO:0003677 12133 2091 19 3 2849 10 1 false 0.9993552636837665 0.9993552636837665 0.0 protein_modification_process GO:0036211 12133 2370 19 5 3518 16 2 false 0.9993802600941692 0.9993802600941692 0.0 nucleoside_catabolic_process GO:0009164 12133 952 19 3 1516 13 5 false 0.9993896712936335 0.9993896712936335 0.0 cytoskeleton GO:0005856 12133 1430 19 1 3226 13 1 false 0.999515878302544 0.999515878302544 0.0 macromolecular_complex_assembly GO:0065003 12133 973 19 2 1603 13 2 false 0.9998937976807473 0.9998937976807473 0.0 protein_complex_assembly GO:0006461 12133 743 19 2 1214 13 3 false 0.999910227250549 0.999910227250549 0.0 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 19 11 7976 18 2 false 0.9999207003775485 0.9999207003775485 0.0 membrane-bounded_organelle GO:0043227 12133 7284 19 11 7980 18 1 false 0.9999361982103367 0.9999361982103367 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 19 5 3611 15 3 false 0.9999365846763677 0.9999365846763677 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 19 5 3220 14 4 false 0.9999464068853882 0.9999464068853882 0.0 cellular_protein_modification_process GO:0006464 12133 2370 19 5 3038 16 2 false 0.9999911786056773 0.9999911786056773 0.0 protein_complex GO:0043234 12133 2976 19 5 3462 17 1 false 0.9999999901237516 0.9999999901237516 0.0 GO:0000000 12133 11221 19 19 0 0 0 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 19 1 147 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 19 1 87 1 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 19 2 1169 2 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 19 3 417 3 1 true 1.0 1.0 1.0 phosphatidylinositol-mediated_signaling GO:0048015 12133 173 19 1 173 1 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 19 1 124 1 2 true 1.0 1.0 1.0